2. Anti-infection Vitamin D Related/Nuclear Receptor
  3. Fungal Androgen Receptor Parasite
  4. Dimethomorph

Dimethomorph 

Cat. No.: HY-B0846 Purity: 99.13%
COA Handling Instructions

Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 µM.

For research use only. We do not sell to patients.

Dimethomorph Chemical Structure

Dimethomorph Chemical Structure

CAS No. : 110488-70-5

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Based on 1 publication(s) in Google Scholar

Dimethomorph Related Antibodies

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  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Dimethomorph is a fungicide belongs to the fungicide group of sterol biosynthesis inhibitor. Dimethomorph can inhibit fungal cell wall formation. Dimethomorph also inhibits androgen receptor (AR) activity in MDA-kb2 cells with an IC20 of 0.263 µM[1][2][3].

In Vitro

Dimethomorph inhibits mycelial growth of the oomycete fungi Phytophthora capsici, P. citrophthora, and P. parasitica with EC50s of <0.1 µg/mL, 0.14 µg/mL, and 0.38 µg/mL, respectively[1].
Dimethomorph inhibits AR activity in a reporter assay in MDA-kb2 human breast cancer cells but not in a yeast antiandrogen screen (IC50s = 0.263 and 38.5 µM, respectively)[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Dimethomorph Related Antibodies
Molecular Weight

387.86

Appearance

Solid

Formula

C21H22ClNO4
CAS No.
SMILES

O=C(N1CCOCC1)/C=C(C2=CC=C(Cl)C=C2)\C3=CC=C(OC)C(OC)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 6.67 mg/mL (17.20 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5782 mL 12.8912 mL 25.7825 mL
5 mM 0.5156 mL 2.5782 mL 5.1565 mL
10 mM 0.2578 mL 1.2891 mL 2.5782 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 0.67 mg/mL (1.73 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 0.67 mg/mL (1.73 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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Dimethomorph Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Dimethomorph110488-70-5FungalAndrogen ReceptorParasitemorpholinefungicidemycelialInhibitorinhibitorinhibit

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