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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
gamma delta T cell
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "gamma delta T cell" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P86804
Synonyms: 4930549J05Rik antibody;
A430104F18Rik antibody;
AW552088 antibody;
Cd247 antibody;
CD3 antibody;
CD3 delta antibody;
CD3 epsilon antibody;
CD3 eta antibody;
CD3 gamma antibody;
CD3 zeta antibody;
CD3H antibody;
CD3Q antibody;
CD3Z antibody;
CD3zeta antibody;
Ctg3 antibody;
FLJ17620 antibody;
FLJ17664 antibody;
FLJ18683 antibody;
FLJ79544 antibody
FLJ94613 antibody;
IMD19 antibody;
Leu-4 antibody;
MGC138597 antibody;
OKT3, delta chain antibody;
OTTHUMP00000032544 antibody;
T cell receptor antibody;
T3 antibody;
T3d antibody;
T3e antibody;
T3g antibody;
T3z antibody;
TCRE antibody;
TCRk antibody;
Tcrz antibody;
TCRzeta antibody
Synonyms: (E)-4-Hydroxy-3-methyl-but-2-enyl diphosphate lithium
Category:
Cat. No.: HY-P99146
Target:
Research Areas:
Infection Neurological Disease Inflammation/Immunology Cancer
CHMFL-PI3KD-317 is a highly potent, selective and orally active PI3Kδ inhibitor, with an IC50 of 6 nM, and exhibits over 10-1500 fold selectivity over other class I, II and III PIKK family isoforms, such as PI3Kα (IC50, 62.6 nM), PI3Kβ (IC50, 284 nM), PI3Kγ (IC50, 202.7 nM), PIK3C2A (IC50, >10000 nM), PIK3C2B (IC50, 882.3 nM), VPS34 (IC50, 1801.7 nM), PI4KIIIA (IC50, 574.1 nM) and PI4KIIIB (IC50, 300.2 nM). CHMFL-PI3KD-317 inhibits PI3Kδ-mediated Akt T308 phosphorylation in Raji cells, with an EC50 of 4.3 nM. CHMFL-PI3KD-317 has antiproliferative effects on cancer cells .
Cat. No.: HY-165398
CAS No.: 13022-42-9
Target:
Research Areas:
Leucylleucine methyl ester is a lysosomotropic agent that can be used to eliminate gamma delta T cells in human peripheral blood .
Cat. No.: HY-P990113
Target:
Research Areas:
Cat. No.: HY-177277
CAS No.: 1549766-06-4
Target:
Research Areas:
HM5023507 is an orally active and selective PI3Kδ/γ inhibitor with IC50s of 4 and 5 μM for PI3Kδ and PI3Kγ over PI3Kβ and PI3Kα. HM5023507 attenuates the PI3Kδ/γ signaling in human basophils. HM5023507 also attenuates the activation and function of human B and T cells and cytokine and IgG production during cocultures, and Th17 differentiation of CD4 T cells. HM5023507 inhibited semiestablished collagen-induced arthritic inflammation in the rat models. HM5023507 can be used for inflammatory diseases like rheumatoid arthritis research .
Cat. No.: HY-P99147
Target:
Research Areas:
Cat. No.: HY-149493
CAS No.: 3047746-40-4
Target:
Research Areas:
IHMT-PI3K-455 (Compound 15u) is a potent, selective, orally active PI3Kγ/δ dual inhibitor with IC50s of 7.1 nM and 0.57 nM for PI3Kγ and PI3Kδ, respectively. IHMT-PI3K-455 suppresses the AKT phosphorylation. IHMT-PI3K-455 inhibits tumor growth by recruiting and activating more CD8 + killing T cells.IHMT-PI3K-455 is used in cancer research .
Cat. No.: HY-184323
Target:
Research Areas:
PPARγ agonist-24 is a peroxisome proliferator-activated receptor gamma agonist with oral effectiveness, a PPARγ IC50 of 1.752 μM, and a PPARγ Ki of 54.81 nM. PPARγ agonist-24 shows higher selectivity toward PPARγ than PPARα and weak activity toward PPARδ. PPARγ agonist-24 enhances PPARγ protein expression in hepatic cells. PPARγ agonist-24 can be used for the research of type 2 diabetes (t2dm) .
Cat. No.: HY-186052
Research Areas:
4-M-HMBPP is a weak agonist for Vγ9Vδ2 T cell activation and a potent competitive inhibitor of HMBPP. 4-M-HMBPP binds to BTN3A1 with high affinity (KD: 26.2 μM), but fails to induce its complex formation with BTN2A1. 4-M-HMBPP can be used in studies on γδ T cell activation .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
