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  4. Leucylleucine methyl ester

Leucylleucine methyl ester is a lysosomotropic agent that can be used to eliminate gamma delta T cells in human peripheral blood.

For research use only. We do not sell to patients.

CAS No. : 13022-42-9

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Other In-stock Forms of Leucylleucine methyl ester:

Leucylleucine methyl ester Related Antibodies

Top Publications Citing Use of Products

    Leucylleucine methyl ester purchased from MedChemExpress. Usage Cited in: EMBO J. 2025 May;44(9):2596-2619.  [Abstract]

    S-palmitoylation of HA-ATG2A detected by ABE assay in HEK293T cells treated with 1 mM LLOMe for indicated times.

    Leucylleucine methyl ester purchased from MedChemExpress. Usage Cited in: J Cell Biol. 2025 Nov 3;224(11):e202404018.  [Abstract]

    U2OS cells were transfected with HaloTag-LRRK2 for 36 h. Cells were then treated with DMSO, LLOME (1 mM), or LLOME+MLi2 for 2 h before fixation. Cells were then stained for RILPL1 and LAMP2.

    Leucylleucine methyl ester purchased from MedChemExpress. Usage Cited in: J Cell Biol. 2025 Nov 3;224(11):e202404018.  [Abstract]

    Quantification of the RILPL1 lysosomes per cell. Cells were treated with DMSO, LLOME (1 mM), or LLOME+MLi2 for 2 h.

    Leucylleucine methyl ester purchased from MedChemExpress. Usage Cited in: J Cell Biol. 2025 Nov 3;224(11):e202404018.  [Abstract]

    HEK293FT cells were transfected with 3xflag-LRRK2 and mCherry-RILPL1 for 24 h. Cells were treated or not with LLOME (1 mM) for 2 h, and lysates were subjected to immunoprecipitation with anti-RFP antibodies. RFP, LRRK2, and pT73-RAB10 were blotted.

    Leucylleucine methyl ester purchased from MedChemExpress. Usage Cited in: J Cell Biol. 2025 Nov 3;224(11):e202404018.  [Abstract]

    HEK293T cells stably expressing GFP-LRRK2 and TMEM192-3xHA were seeded and treated with DMSO, LLOME (1 mM), or LLOME + MLi2 24 h later. Lysosomes were purified with anti-HA beads following the LYSO-IP technique. Lysosomes were then lysed, and their content was analyzed via immunoblotting.

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    Description

    Leucylleucine methyl ester is a lysosomotropic agent that can be used to eliminate gamma delta T cells in human peripheral blood[1].

    Molecular Weight

    258.36

    Formula

    C13H26N2O3
    CAS No.
    SMILES

    CC(C)C[C@H](N)C(N[C@@H](CC(C)C)C(OC)=O)=O
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.
    Purity & Documentation
    References
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    Leucylleucine methyl ester Related Classifications

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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Leucylleucine methyl ester13022-42-9Biochemical Assay ReagentsPBMCLysosomotropic Agentgamma delta T cellInhibitorinhibitorinhibit

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