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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
61 Results for "
glucagon-like peptide-1 receptor (GLP-1-R)
" in MedChemExpress (MCE) Product Catalog:
Products (61)
61 Results for "glucagon-like peptide-1 receptor (GLP-1-R)" in MCE Product Catalog:
7
7 Publications Verification
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GLP-1R Antagonist 1 (compound 5d) is an orally active, CNS penetrant and non-competitive antagonist of glucagon-like peptide 1 receptor (GLP-1R), with an IC50 of 650 nM .
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Danuglipron (PF-06882961) is an orally active glucagon-like peptide-1 receptor (GLP-1R) agonist. Danuglipron has the potential for type 2 diabetes research .
3
3 Cited Publications
Synonyms: LY3502970; GLP-1 receptor agonist 1
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Orforglipron (LY3502970) (Compound 67) is an orally active agonist for Glucagon-like peptide-1 receptor (GLP-1R), which exhibits potency in ameliorates the type 2 diabete .
3
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3
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3
3 Cited Publications
Synonyms: LY3502970 hemicalcium hydrate; GLP-1 receptor agonist 1 hemicalcium hydrate
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Orforglipron hemicalcium hydrate (LY3502970 hemicalcium hydrate; GLP-1 receptor agonist 1 hemicalcium hydrate) is the calcium salt hydrate form of Orforglipron (HY-112185). Orforglipron is an orally active agonist for Glucagon-like peptide-1 receptor (GLP-1R), which exhibits potency in ameliorating the type 2 diabete .
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2
2 Cited Publications
Cat. No.: HY-P81160
Synonyms: glucagon like peptide-1 receptor; GLP 1 R; GLP 1 receptor; GLP 1R; Glp1r; GLP; glp1r; glucagon like peptide 1 receptor; RATGL1RCP; Glip; MGC138331; GLP-1-R; GLP1R_HUMAN; glucagon-like peptide 1 receptor; GLP-1 receptor; GLP-1-R; GLP-1R; Precursor.
2
2 Cited Publications
Cat. No.: HY-P700468
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GLP1R; GLP-1-R; glucagon like peptide 1 receptor; Seven Transmembrane Helix receptor; glucagon-like peptide 1 receptor; GLP1 receptor; GLP-1R; GLP-1; GLP-1 receptor
Species:
Human
Source:
HEK293
1
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1
1 Cited Publications
Cat. No.: HY-P72206
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: GLP1R; GLP-1-R; glucagon like peptide 1 receptor; Seven Transmembrane Helix receptor; glucagon-like peptide 1 receptor; GLP1 receptor; GLP-1R; GLP-1; GLP-1 receptor
Species:
Mouse
Source:
E. coli
Cat. No.: HY-160734
CAS No.: 2685823-26-9
Synonyms: GSBR-1290
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Aleniglipron (GSBR-1290) is an orally active glucagon-like peptide-1 receptor (GLP-1R) agonist, with an EC50 value of less than 0.1 nM in HDB cell lines in cAMP stimulation assays. Aleniglipron selectively activates the Gαs-cAMP signaling pathway of GLP-1R without β-arrestin recruitment. Aleniglipron induces insulin release, promotes glucose clearance, reduces food intake and decreases body weight. Aleniglipron is applicable to research related to type 2 diabetes and obesity .
Cat. No.: HY-177295
CAS No.: 2572566-11-9
Synonyms: LY3549492
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Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
Naperiglipron (LY3549492) is an orally active Glucagon-like peptide 1 receptor (GLP-1R) agonist with an EC50 of 1.14 nM for hGLP-1R. Naperiglipron significantly decreases the level of blood glucose in GLP-1R knock-in mouse models. Naperiglipron inhibits PDE10A1 enzyme activity (IC50: 7.43 μM) with a weak hERG inhibitory activity. Naperiglipron can be used for type II diabetes mellitus (T2DM) and obesity research .
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GLP-1 receptor agonist 2 is a glucagon-like peptide-1 receptor (GLP-1R) agonist .
Synonyms: GLP-1 receptor agonist 9
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PF-06954522 is a glucagon-like peptide-1 receptor (GLP-1R) agonist. PF-06954522 is applicable to research related to type 2 diabetes .
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LSN3318839 is an orally active positive modulator of the glucagon-like peptide-1 receptor (GLP-1R). LSN3318839 can increase the secretion of insulin and has the effect of lowering blood sugar .
Cat. No.: HY-P10929
CAS No.: 2460751-66-8
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Cat. No.: HY-45894
CAS No.: 1118767-16-0
Synonyms: Semaglutide side chain
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Cat. No.: HY-P10018
CAS No.: 1596343-09-7
Synonyms: SAR425899
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V-0219 is an orally active glucagon-like peptide-1 receptor (GLP-1R) positive allosteric modulator. V-0219 potentiates GLP-1R stimulation, and enhances GLP-1-induced cAMP production and insulin secretion. V-0219 potentiates glucose-dependent insulin secretion. V-0219 improves glucose handling in normal and diabetic rodents. V-0219 can be used for the research of obesity-associated diabetes .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
