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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
24 Results for "
glucose-6-phosphate dehydrogenase
" in MedChemExpress (MCE) Product Catalog:
Products (24)
24 Results for "glucose-6-phosphate dehydrogenase" in MCE Product Catalog:
22
22 Publications Verification
Cat. No.: HY-W010342
CAS No.: 329-89-5
Target:
Research Areas:
6-Aminonicotinamide, a potent antimetabolite of nicotinamide, is competitive NADP +-dependent enzyme glucose-6-phosphate dehydrogenase (G6PD) inhibitor (Ki=0.46 μM). 6-Aminonicotinamide resultis ATP depletion and synergizes with DNA-crosslinking chemotherapy agents, such as Cisplatin (HY-17394), in killing cancer cells .
10
10 Cited Publications
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Research Areas:
G6PD activator AG1 is a potent and selective glucose-6-phosphate dehydrogenase (G6PD) agonist with an EC50 of 3 μM. G6PD is an oxidoreductase that catalyzes the oxidation of glucose-6-phosphate to 6-phosphogluconolactone and the simultaneous reduction of NAD phosphate (NADP) to reduced NADP (NADPH). G6PD activator AG1 can reduce hemolysis of human erythrocytes .
9
9 Cited Publications
Cat. No.: HY-W107464
CAS No.: 2457232-14-1
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G6PDi-1 is a reversible and non-competitive glucose-6-phosphate dehydrogenase (G6PD) inhibitor with an IC50 of 0.07 μM for human G6PD. G6PDi-1 depletes NADPH most strongly in lymphocytes. G6PDi-1 markedly decreases inflammatory cytokine production in T cells .
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Category:
Alkaloids Leguminosae Other Alkaloids Metabolic Disease Plants Vicia faba L. Disease Research Fields
Target:
Cat. No.: HY-W012530
CAS No.: 156-06-9
Category:
Microorganisms Ketones, Aldehydes, Acids Other Diseases Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields
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Target:
Cat. No.: HY-125863C
CAS No.: 9001-40-5
Synonyms: G6PD, Bacillus sp.
Target:
Research Areas:
Glucose-6-phosphate dehydrogenase, Bacillus sp. (G6PD, Bacillus sp.) (EC 1.1.1.49) is an NADP-dependent antioxidant metabolic enzyme. Glucose-6-phosphate dehydrogenase, Bacillus sp. is induced by sublethal doses of Menadione (HY-B0332) and increasing concentrations of NaCl in Bacillus sp. F26. Glucose-6-phosphate dehydrogenase, Bacillus sp. catalyzes the oxidation of glucose-6-phosphate (G6P) to 6-phosphoglucono-δ-lactone, while reducing NADP + to NADPH, providing reducing power for the antioxidant defense system and cellular redox balance of Bacillus sp. F26. Glucose-6-phosphate dehydrogenase, Bacillus sp. is used in research related to diabetic complications .
Cat. No.: HY-W017960
CAS No.: 1149-23-1
Synonyms: Et-HE; 1,4-DHP
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Research Areas:
Diludine (BNP-7787) is an orally effective feed additive. Diludine reduces the activity of G6PD and increases the level of superoxide dismutase (SOD). Diludine reduces the mutagenic effect of environmental pollutants, protects parental reproductive systems and improves offspring quality. Diludine is mainly applied during the transition period of dairy cows to increase milk yield and milk fat content, and improve health status during parturition. Diludine can be used in animal feeding research .
Cat. No.: HY-W587796
CAS No.: 2641-81-8
Synonyms: 6-PGδL; 6-Phosphonoglucono-D-lactone
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Research Areas:
6-Phosphoglucono-δ-lactone (6-PGδL), a reversal substrate of glucose-6-phosphate dehydrogenase (G6PD), is an intermediate compound in the oxidative branch of the pentose phosphate pathway (PPP). 6-Phosphoglucono-δ-lactone produced from D-glucose-6-phosphate by glucose-6-phosphate dehydrogenase (G6PDH) and is converted to 6-phosphoglutonate by lactonase. 6-Phosphoglucono-δ-lactone can be used for heart failure, type 2 diabetes and cancers research .
Cat. No.: HY-W016203
CAS No.: 114-76-1
Synonyms: Sodium phenylpyruvate
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Research Areas:
Phenylpyruvic acid sodium is a endogenous metabolite that participates in the synthesis of 3-phenyllactic acid (PLA) by lactate dehydrogenase. Phenylpyruvic acid is a precursor of the antifungal compound phenyllactic acid. Phenylpyruvic acid can improve the antifungal activity of eight lactic acid bacterial strains through the addition into a dedined growth medium. Phenylpyruvic acid demonstrates improved inhibitory activity against fungal bread contaminants Aspergillus niger and Penicillium roqueforti. Phenylpyruvic acid affects enzyme activity of the pentose phosphate pathway involved in the oxidative phase in rat brain homogenates. Phenylpyruvic acid can reduce glucose-6-phosphate dehydrogenase activity .
Cat. No.: HY-W012530R
CAS No.: 156-06-9
Cat. No.: HY-125863A
CAS No.: 9001-40-5
Synonyms: G6PD (Leuconostoc sp., recombinant)
Target:
Research Areas:
Glucose-6-phosphate dehydrogenase (Leuconostoc sp., recombinant) (G6PD (Leuconostoc sp., recombinant)) (EC 1.1.1.49) is an NADP-dependent antioxidant metabolic enzyme. Glucose-6-phosphate dehydrogenase (Leuconostoc sp., recombinant) can be induced by sublethal doses of Menadione (HY-B0332) and increasing concentrations of NaCl. Glucose-6-phosphate dehydrogenase (Leuconostoc sp., recombinant) catalyzes the oxidation of glucose-6-phosphate (G6P) to 6-phosphoglucono-δ-lactone, while reducing NADP + to NADPH, providing reducing power for the antioxidant defense system and cellular redox balance of bacteria. Glucose-6-phosphate dehydrogenase (Leuconostoc sp., recombinant) is used in research related to diabetic complications .
Cat. No.: HY-125863B
CAS No.: 9001-40-5
Synonyms: G6PD (yeast, recombinant)
Research Areas:
Glucose 6-phosphate dehydrogenase (yeast, recombinant) (G6PD (yeast, recombinant)) is a recombinant enzyme requiring NADP + as a coenzyme. Glucose 6-phosphate dehydrogenase (yeast, recombinant) catalyzes the oxidative dehydrogenation of glucose-6-phosphate to form 6-phosphoglucono-δ-lactone, as well as the reduction of NADP + to NADPH. Glucose 6-phosphate dehydrogenase (yeast, recombinant) relies on the amino acid Arg-52 to bind NADP +. Glucose 6-phosphate dehydrogenase (yeast, recombinant) undergoes competitive inhibition by NADPH and strong inhibition by zinc ions (Zn 2+). Glucose 6-phosphate dehydrogenase (yeast, recombinant) is an enzyme in the pentose phosphate pathway, which is one of the glucose metabolic pathways. Glucose 6-phosphate dehydrogenase (yeast, recombinant) can be used for the quantitative detection of ATP, glucose and creatine kinase .
Cat. No.: HY-W010342R
CAS No.: 329-89-5
Target:
Research Areas:
6-Aminonicotinamide, a potent antimetabolite of nicotinamide, is competitive NADP+-dependent enzyme glucose-6-phosphate dehydrogenase (G6PD) inhibitor (Ki=0.46 μM). 6-Aminonicotinamide resultis ATP depletion and synergizes with DNA-crosslinking chemotherapy agents, such as Cisplatin (HY-17394), in killing cancer cells .
Cat. No.: HY-E71039
Target:
Research Areas:
Chemically modified Glucose-6-phosphate Dehydrogenase, Leuconostoc mesenteroides is a cytosolic enzyme. Chemically modified Glucose-6-phosphate Dehydrogenase, Leuconostoc mesenteroides is in the pentose phosphate pathway, a metabolic pathway that supplies reducing energy to cells (such as erythrocytes) by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH) .
Cat. No.: HY-125863D
Synonyms: G6PD, Torula yeast
Target:
Research Areas:
Glucose-6-phosphate dehydrogenase, Torula yeast (G6PD, Torula yeast) (EC 1.1.1.49) is an NADP-dependent antioxidant metabolic enzyme. Glucose-6-phosphate dehydrogenase, Torula yeast can be induced by sublethal doses of Menadione (HY-B0332) and increasing concentrations of NaCl. Glucose-6-phosphate dehydrogenase, Torula yeast catalyzes the oxidation of glucose-6-phosphate (G6P) to 6-phosphoglucono-δ-lactone, while reducing NADP + to NADPH, providing reducing power for the antioxidant defense system and cellular redox balance of bacteria. Glucose-6-phosphate dehydrogenase, Torula yeast is used in research related to diabetic complications .
Cat. No.: HY-P70283
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: G6PD; glucose-6-phosphate dehydrogenase (NADP(+)); glucose-6-phosphate dehydrogenase; Epididymis Secretory Sperm Binding Protein; glucose-6-phosphate 1-dehydrogenase; CNSHA1; G6PD1
Species:
Human
Source:
HEK293
Cat. No.: HY-136783
CAS No.: 333311-00-5
G6PD-IN-2 is a Plasmodium falciparum glucose-6-phosphate dehydrogenase (G6PD) inhibitor with an IC50 value of 0.2 μM. G6PD-IN-2 exerts weak inhibitory activity on Plasmodium falciparum glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (PfGluPho) with an IC50 value of 22.0 μM. G6PD-IN-2 inhibits growth of Plasmodium falciparum 3D7 strain and exhibits low cytotoxicity in hepatocytes. G6PD-IN-2 can be used for the research of malaria .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
