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Results for "

glycosylation sites

" in MedChemExpress (MCE) Product Catalog:

17

Inhibitors & Agonists

1

Fluorescent Dyes

8

Biochemical Assay Reagents

2

Peptides

1

MCE Kits

1

Natural
Products

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N7110
    6-Hydroxyflavone
    2 Publications Verification

    		 Akt ERK JNK GABA Receptor Neurological Disease Metabolic Disease Inflammation/Immunology
    6-Hydroxyflavone is an orally effective flavonoid compound. 6-Hydroxyflavone can inhibit LPS (HY-D1056) -induced NO production and has anti-inflammatory effects. 6-Hydroxyflavone promotes osteoblast differentiation by activating AKT, ERK 1/2 and JNK signaling pathways. 6-Hydroxyflavone has an inhibitory effect on bovine hemoglobin (BHb) glycosylation. 6-Hydroxyflavone has a kidney protective effect. In addition, 6-Hydroxyflavone enhances GABA-induced current through the Benzodiazepine sites of γ-aminobutyric acid (GABAA) receptors. 6-Hydroxyflavone shows a clear preference for α2 - and α3 - subtypes, which play an anti-anxiety role .
    6-Hydroxyflavone
  • HY-NP163D
    Wheat germ agglutinin-AF594

    WGA-AF594

    		 Fluorescent Dye Cancer
    Wheat germ agglutinin-AF594 (WGA-AF594) is a plant lectin that contains the fluorescent dye AF594, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF594 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA .
    Wheat germ agglutinin-AF594
  • HY-NP163E
    Wheat germ agglutinin-AF647

    WGA-AF647

    		 Fluorescent Dye Cancer
    Wheat germ agglutinin-AF647 (WGA-AF647) is a plant lectin that contains the fluorescent dye AF647, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF647 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA .
    Wheat germ agglutinin-AF647
  • HY-124890
    Thr101

    		Phosphomannose Isomerase (PMI) Glucose-6-Phosphate Isomerase (GPI) Metabolic Disease
    Thr101 is an inhibitor (IC50=2.9 μM) of phosphomannose isomerase (PMI).PMI can compete with phosphomannose mutase 2 (PMM2) for the binding site of Man-6-P and convert mannose-6-phosphate (Man-6-P) into fructose-6-phosphate (Fru-6-P) .Thr101 only specifically inhibits PMI and not PMM2. Thr101 can be used for research of congenital disorder of glycosylation type Ia (CDG-Ia) .
    Thr101
  • HY-P2929B
    PNGase F (Immobilized, Microspin)

    		Glycosidase Others
    PNGase F (Immobilized, Microspin) is a resin in which PNGase F (peptide N-glycosidase F) is covalently coupled to agarose beads, and it is used to remove N-glycans from antibodies, fusion proteins and other N-glycosylated proteins. The enzyme is recombinantly expressed in Escherichia coli, with its sequence derived from Flavobacterium meningsepticum .
    PNGase F (Immobilized, Microspin)
  • HY-NP163
    Wheat germ agglutinin-AF350

    WGA-AF350

    		 Fluorescent Dye Cancer
    Wheat germ agglutinin-AF350 (WGA-AF350) is a plant lectin that contains the fluorescent dye AF350, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF350 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA .
    Wheat germ agglutinin-AF350
  • HY-176559
    LacNAc-VC-PAB-MMAE

    		Drug-Linker Conjugates for ADC Cancer
    LacNAc-VC-PAB-MMAE is a component of an Antibody-Drug Conjugate (ADC). LacNAc-VC-PAB-MMAE is assembled onto the N-glycosylation site of Trastuzumab (HY-P9907) by WT Endo-S2 .
    LacNAc-VC-PAB-MMAE
  • HY-NP163I
    Wheat germ agglutinin-AF680

    WGA-AF 680

    		 Fluorescent Dye Cancer
    Wheat germ agglutinin-AF680 (WGA-AF 680) is a plant lectin that contains the fluorescent dye AF680, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF680 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA .
    Wheat germ agglutinin-AF680
  • HY-NP163J
    Wheat germ agglutinin-AF405

    WGA-AF 405

    		 Fluorescent Dye Cancer
    Wheat germ agglutinin-AF405 (WGA-AF 405) is a plant lectin that contains the fluorescent dye AF405, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF405 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA .
    Wheat germ agglutinin-AF405
  • HY-177787A
    2'-Deoxy-N-methyl-AMP ammonium

    		Nucleoside Antimetabolite/Analog Others
    2'-Deoxy-N-methyl-AMP ammonium is an N6-substituted adenine nucleotide derivative and a glycosyl donor. On one hand, 2'-Deoxy-N-methyl-AMP ammonium acts as a specific substrate for N6-methyl-AMP aminohydrolase, and it is catalytically converted to dIMP to participate in the nucleotide metabolic cycle. On the other hand, 2'-Deoxy-N-methyl-AMP ammonium also serves as a guanosine diphosphate (GDP)-linked fucose derivative donor, driving site-specific glycoconjugation of proteins under the mediation of α-1,3-fucosyltransferase. 2'-Deoxy-N-methyl-AMP ammonium is an important molecular tool for investigating the mechanisms of nucleotide modification and protein glycosylation .
    2'-Deoxy-N-methyl-AMP ammonium
  • HY-NP163H
    Wheat germ agglutinin-AF750

    WGA-AF750

    		 Fluorescent Dye Cancer
    Wheat germ agglutinin-AF750 (WGA-AF750) is a plant lectin that contains the fluorescent dye AF750, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF750 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA .
    Wheat germ agglutinin-AF750
  • HY-P4027
    HCV-1 e2 Protein (554-569)

    		HCV Infection
    HCV-1 e2 Protein (554-569) is one of the main antigenic regions of HCV envelope 2 (e2) protein. The HCV-1 e2 Protein (554-569) contains a putative n-glycosylation site, which was previously thought to influence the immune recognition of e2 .
    HCV-1 e2 Protein (554-569)
  • HY-P4027A
    HCV-1 e2 Protein (554-569) TFA

    		HCV Infection
    HCV-1 e2 Protein (554-569) TFA is one of the main antigenic regions of HCV envelope 2 (e2) protein. The HCV-1 e2 Protein (554-569) TFA contains a putative N-glycosylation site, which was previously thought to influence the immune recognition of e2 .
    HCV-1 e2 Protein (554-569) TFA
  • HY-E70568
    Protease (O-glycan Cleaving)

    		Ser/Thr Protease Others
    Protease (O-glycan Cleaving) is recombinantly expressed from E.coli and contains a His tag. Protease (O-glycan Cleaving) is an O-glycan-dependent protease that digests proteins carrying mucin-type O-glycans, including sialylated substrates, glycosylated Ser and Thr residues at the N terminus. Protease (O-glycan Cleaving) digests a variety of O-glycan structures, including sialylated glycosylated core 1 and core 2 structures and Tn antigen. Protease (O-glycan Cleaving) does not digest terminally modified serine or threonine residues, nor does it digest N-glycosylation sites on glycoproteins.
    Protease (O-glycan Cleaving)
  • HY-NP163B
    Wheat germ agglutinin-AF532

    WGA-AF532

    		 Fluorescent Dye Cancer
    Wheat germ agglutinin-AF532 (WGA-AF532) is a plant lectin that contains the fluorescent dye AF532, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF532 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA .
    Wheat germ agglutinin-AF532
  • HY-NP163K
    Wheat germ agglutinin-AF430

    WGA-AF 430

    		 Fluorescent Dye Cancer
    Wheat germ agglutinin-AF430 (WGA-AF 430) is a plant lectin that contains the fluorescent dye AF430, which can be used to identify carbohydrate chains. Wheat germ agglutinin-AF430 can be used to assess abnormal glycosylation levels in the body. The specific glycosylation detection sites of Wheat germ agglutinin is bis-GlcNAc, SA .
    Wheat germ agglutinin-AF430
  • HY-180467
    Neu5Ac-2Galβ1-3Glc-oxazoline-(2)Me

    		ADC Linker Cancer
    Neu5Ac-2Galβ1-3Glc-oxazoline-(2)Me (Compound G12) is a disaccharide linker. Neu5Ac-2Galβ1-3Glc-oxazoline-(2)Me can be efficiently recognized by the endo-glycosidase Endo-S2 and can be directedly transferred to the conserved N-glycosylation site (Asn297 position) of the antibody's Fc domain through enzymatic catalytic reactions, thereby achieving site-specific modification of the antibody. Neu5Ac-2Galβ1-3Glc-oxazoline-(2)Me can be used for for the synthesis of antibody-conjugated drugs (ADCs) .
    Neu5Ac-2Galβ1-3Glc-oxazoline-(2)Me

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