2 Results for "

healthy gastric epithelial cells

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "healthy gastric epithelial cells" in MCE Product Catalog:

Cat. No.: HY-183714
CAS No.: 2922798-57-8
Research Areas:  

Cancer

Anticancer agent 325 is an apoptosis/autophagy inducer and anticancer agent. Anticancer agent 325 exhibits cytotoxic activity against gastric cancer cells, with no significant effect on healthy gastric epithelial cells. Anticancer agent 325 enhances the expression of activated/cleaved Caspase-3 to promote apoptosis. Anticancer agent 325 also enhances the cleavage of PARP, a downstream marker of apoptosis, promotes LC3B lipidation, and activates autophagy. Anticancer agent 325 can be used in the research of gastric cancer .
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Cat. No.: HY-P992508
Synonyms: SX001

Target:  

Claudin

Research Areas:  

Cancer

SPX-101 (SX001) is a humanized monoclonal antibody targeting CLDN18.2. CLDN18.2 is only transiently expressed in the differentiated epithelial cells of the gastric mucosa and is hardly found in healthy tissues, thus having an extremely wide therapeutic window. SPX-101 can be used for the study of solid tumors.
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