19 Results for "

human plasma albumin

" in MedChemExpress (MCE) Product Catalog:
Products (19)

19 Results for "human plasma albumin" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-P1956
CAS No.: 70024-90-7
Synonyms: human serum albumin
HSA Protein (Human serum albumin) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. HSA Protein exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. HSA Protein can block the inhibitory effect of GML on human T cells, providing protective function for T cells. HSA Protein is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, NF-κB, and peroxynitrite (ONOO -) in the vascular wall, contributing to the reduction of blood pressure .
This product is recombinant HSA Protein expressed in a microbial expression system.
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1 Cited Publications
Cat. No.: HY-P1956A
CAS No.: 70024-90-7
Synonyms: human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg)
HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) (Human serum albumin (Cell culture grade, Endotoxin<0.125 EU/mg)) is the most abundant protein in plasma and is a major determinant of plasma oncotic pressure. HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) exhibits antioxidant, anticoagulant, anti-inflammatory, anti-platelet aggregation activities as well as colloid osmotic action. HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) can block the inhibitory effect of GML on human T cells, providing protective function for T cells. HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) is also associated with cardiovascular diseases and can partially prevent the LPS (HY-D1056) induced oxidative stress, as well as the upregulation of NF-κB, iNOS, and peroxynitrite (ONOO -) in the vascular wall, contributing to the reduction of blood pressure. HSA Protein (Cell culture grade, Endotoxin<0.125 EU/mg) can be used for in vitro cell culture .
This product is human serum albumin recombinantly expressed in an Escherichia coli expression system.
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Cat. No.: HY-P4070
CAS No.: 1188379-43-2
Target:  

Insulin Receptor

Research Areas:  

Metabolic Disease

Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec modulates insulin receptor activity, controls blood glucose levels, reduces HbA1c levels, and binds reversibly to human serum albumin. Insulin icodec can be used for the research of type 2 diabetes mellitus .
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Cat. No.: HY-150097
Purity:  ≥99.0%
Recombinant Human Serum Albumin (rHSA) is a non-glycosylated monomeric plasma protein that acts as a core factor for maintaining plasma colloid osmotic pressure. Recombinant Human Serum Albumin (rHSA) possesses multiple physiological functions including carrier, metabolic regulation, detoxification, antioxidation and enzyme mimicking. Recombinant Human Serum Albumin (rHSA) not only scavenges reactive oxygen and nitrogen species via specific residues and binds a variety of endogenous and exogenous compounds to maintain redox homeostasis, but also serves as a biomarker for multiple diseases such as cancer and inflammation. Recombinant Human Serum Albumin (rHSA) broadly supports the development of implantable materials, surgical adhesives and ligand capture, and can be used for research on critical illnesses including hypovolemia, liver failure, severe sepsis and various types of trauma resuscitation .
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Cat. No.: HY-P99397
CAS No.: 1414386-05-2
Synonyms: ALX 0761; M 1095

Target:  

Interleukin Related MMP

Research Areas:  

Inflammation/Immunology

Sonelokimab (ALX 0761) is a trivalent bispecific nanobody composed of camel derived humanized IL-17F antibodies, IL-17A/F antibodies, and serum albumin VHH antibodies. Sonelokimab can prolong the plasma half-life by binding to human serum albumin. Sonelokimab can be used for research on rheumatoid arthritis and psoriasis .
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Cat. No.: HY-NP002L
Synonyms: Canine Serum albumin
CSA Protein (Canine) (Canine Serum Albumin) is a plasma protein derived from dogs. CSA Protein (Canine) exhibits greater flexibility than human serum albumin and bovine serum albumin. Serum albumin is a multifunctional protein with exceptional ligand-binding capacity, which enables it to act as a transport molecule for various metabolites, drugs, nutrients, metals and other molecules .
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Cat. No.: HY-NP002J
CAS No.: 9048-46-8
Horse Serum Albumin is an abundant, multifunctional mammalian plasma protein and transport molecule. Horse Serum Albumin acts as an allergen, exhibits high cross-reactivity with serum albumins from other mammals, and contains epitope regions recognizable by antibodies. Horse Serum Albumin binds a variety of metabolites, drugs, nutrients, metals and other molecules .
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Cat. No.: HY-B0890
CAS No.: 64092-48-4
Synonyms: McN-2783-21-98
Zomepirac sodium salt (McN-2783-21-98) is an orally active prostaglandin synthetase inhibitor. Zomepirac sodium salt blocks prostaglandin synthesis and inhibits Collagen (HY-P72147)- or Epinephrine (HY-B0447)-induced platelet aggregation. Zomepirac sodium salt can be used for the research of postoperative pain and osteoarthritis .
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Cat. No.: HY-NP180
Progesterone/BSA is a conjugate of Progesterone (HY-N0437) and bovine serum albumin (BSA). Progesterone/BSA cannot penetrate the plasma membrane of human sperm, but still rapidly elevates intracellular free calcium and induces the acrosome reaction. Progesterone/BSA can also act as a probe to specifically bind to progesterone-binding proteins on the membrane of rat brain synaptosomes .
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Cat. No.: HY-159563
CAS No.: 2778229-31-3
Research Areas:  

Cancer

Mal-va-mac-SN38 is a drug-linker conjugate for ADC. Mal-va-mac-SN38 contains a ADC cytotoxin SN-38 (HY-13704) and a linker (HY-126364). Mal-va-mac-SN38 can rapidly and covalently bind with endogenous albumin in vivo, resulting in the formation of HSA-va-mac-SN38. Mal-va-mac-SN38 demonstrates exceptional stability in human plasma, and has anti-tumor and anti-metastasis effect .
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Cat. No.: HY-113553
CAS No.: 102185-28-4
Synonyms: (p-Aminophenyl)phosphocholine; p-Aminophenylphosphorylcholine; 4-APPC
Research Areas:  

Others

4-Aminophenylphosphorylcholine ((p-Aminophenyl) phosphocholine; p-Aminophenylphosphorylcholine; 4-APPC) is a phosphatidylcholine derivative that serves as a coupling ligand and antigen probe. When conjugated with gold nanoclusters, the phosphocholine head epitope of 4-Aminophenylphosphorylcholine is specifically recognized by anti-Pc IgM and CRP. It can be covalently coupled to human serum albumin (HSA) or glutathione-protected gold nanoclusters (Au-GSH) via covalent chemistry, respectively. The 4-Aminophenylphosphorylcholine-HSA complex acts as an ELISA coating antigen for detecting endogenous anti-Pc IgM antibodies in plasma; 4-Aminophenylphosphorylcholine-modified Au-GSH can be used to construct an ultra-stealthy NIR-II fluorescent gold nanocluster probe for imaging-related studies in mouse breast cancer and colon cancer models .
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Cat. No.: HY-B0890A
CAS No.: 33369-31-2
Synonyms: McN-2783-21-98 free acid
Zomepirac (McN-2783-21-98 free acid) is an orally active prostaglandin synthetase inhibitor. Zomepirac blocks prostaglandin synthesis and inhibits Collagen (HY-P72147)- or Epinephrine (HY-B0447)-induced platelet aggregation. Zomepirac can be used for the research of postoperative pain and osteoarthritis .
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Cat. No.: HY-B0890R
CAS No.: 64092-48-4
Synonyms: McN-2783-21-98 (Standard)
Zomepirac sodium salt (Standard) is the analytical standard of Zomepirac sodium salt (HY-B0890). This product is intended for research and analytical applications. Zomepirac sodium salt (McN-2783-21-98) is an orally active prostaglandin synthetase inhibitor. Zomepirac sodium salt blocks prostaglandin synthesis and inhibits Collagen (HY-P72147)- or Epinephrine (HY-B0447)-induced platelet aggregation. Zomepirac sodium salt can be used for the research of postoperative pain and osteoarthritis .
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Cat. No.: HY-P11924
Research Areas:  

Cancer

TATE-DA-I is a somatostatin receptor 2 (SSTR2) ligand with an IC50 of 25.3 nM. TATE-DA-I binds to albumin to prolong its circulation retention time and also exhibits enhanced tumor accumulation capacity. TATE-DA-I enables clear visualization of SSTR2-positive tumors in SPECT/CT imaging. TATE-DA-I can be used in cancer-related research .
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Cat. No.: HY-W344337
CAS No.: 72967-59-0
Synonyms: Furosemide acyl-β-D-glucuronide
Target:  

Drug Metabolite

Research Areas:  

Cardiovascular Disease Cancer

Furosemide AG (Furosemide acyl-β-D-glucuronide) is an acyl-β-D-glucuronide metabolite of Furosemide (HY-B0135). Furosemide AG can be used in the research of neutropenia and thrombocytopenia .
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Cat. No.: HY-W713877
CAS No.: 188717-17-1
Synonyms: Montelukast AG
Target:  

Drug Metabolite

Research Areas:  

Others

Montelukast acyl-b-D-glucuronide (Montelukast AG) is a acyl glucuronide metabolite of Montelukast (HY-13315A) .
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Cat. No.: HY-181741
Target:  

Cathepsin

Research Areas:  

Inflammation/Immunology

PI3K-001 is a cathepsin B-responsive prodrug and antifibrotic agent. PI3K-001 undergoes cathepsin B-mediated cleavage of the Val-Ala linker in fibrotic lung lesions to release an active PI3K inhibitor payload, while it remains stable in healthy tissues. PI3K-001 improves collagen deposition, tissue collapse and alveolar injury in fibrotic lung tissues. PI3K-001 is applicable for the research of pulmonary fibrosis .
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Cat. No.: HY-184292
COX-2-IN-67 is an orally active, blood-brain barrier permeable multi-target inhibitor that potently targets COX-2 (IC50=0.07 μM), hCA IX (Ki=62.7 nM) and hBuChE (IC50=0.47 μM). COX-2-IN-67 alleviates oxidative stress and liver stress, improves glucose homeostasis and insulin sensitivity, and optimizes lipid profiles. Meanwhile, COX-2-IN-67 effectively reduces the levels of neuroinflammatory markers and improves hippocampus-dependent cognitive function in a high-fat diet-induced rat model. COX-2-IN-67 can be used for the research of metabolic dysfunction-associated mild cognitive impairment .
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Cat. No.: HY-D3570
Target:  

Fluorescent Dye

Research Areas:  

Others

AF405 DBCO is a blue fluorescent dye derivative containing a dibenzocyclooctyne (DBCO) group. AF405 DBCO reacts rapidly with azide-labeled biomolecules at room temperature without the need for a metal catalyst, enabling copper-free click chemistry (SPAAC) for applications in live-cell imaging, flow cytometry, super-resolution microscopy, and other research fields .
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