16 Results for "

leukotriene C/D

" in MedChemExpress (MCE) Product Catalog:
Products (16)

16 Results for "leukotriene C/D" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P700729
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GGT1; GGT 1; Prev. GGT; Gamma-Glutamyltranspeptidase; D22S732; Gamma-Glutamyltransferase; D22S672; Glutathione Hydrolase; CD224; CD224 Antigen; Glutathione Hydrolase 1 Proenzyme; GGT1 Protein; Gamma-Glutamyltranspeptidase 1; GGTD; leukotriene-C4 Hydrolase
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-13448
CAS No.: 69049-73-6
Purity:  98.19%
Synonyms: FPL 59002
Nedocromil suppresses the action or formation of multiple mediators, including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2).
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Cat. No.: HY-113446S
CAS No.: 1441421-73-3
Purity:  97.9%
Leukotriene C4-d5 is the deuterium labeled Leukotriene C4. Leukotriene C4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4.
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Cat. No.: HY-126716S
Leukotriene C4-d5 methyl ester is the deuterium labeled Leukotriene C4 methyl ester .
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Cat. No.: HY-U00364
CAS No.: 104961-19-5
CI-949 is an allergic mediator release inhibitor, which inhibits histamine, leukotriene C4/D4 (LTC4/LTD4), and thromboxane B2 (TXB2) release with IC50s of 11.4 μM, 0.5 μM and 0.1 μM, respectively.
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Cat. No.: HY-106064A
CAS No.: 88851-62-1
Synonyms: U 60257B
Piriprost potassium (U 60257B) is an inhibitor of Glutathione-S-transferase and leukotriene biosynthesis inhibitor. Piriprost potassium inhibits the biosynthesis of leukotriene C/D without affecting cyclooxygenase-mediated arachidonic acid metabolites. Piriprost potassium increases the activity of alkaline phosphatase (ALP). Piriprost potassium antagonizes contractions induced by leukotriene C/D in vitro. Piriprost potassium is used in asthma research .
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Cat. No.: HY-16344
CAS No.: 69049-74-7
Synonyms: FPL 59002KP; Nedocromil disodium salt
Nedocromil sodium suppresses the action or formation of multiple mediators, including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2).
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Cat. No.: HY-17492S1
CAS No.: 2140305-18-4
Synonyms: ICI 204219-13C,d3
Zafirlukast- 13C,d3 is the 13C- and deuterium labeled Zafirlukast. Zafirlukast (ICI 204219) is a potent orally active leukotriene D4 (LTD4) receptor antagonist. Zafirlukast shows anti-asthmatic, anti-inflammatory and anti-bacterial effects.
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Cat. No.: HY-17492S2
Synonyms: ICI 204219-13C,d6
Zafirlukast- 13C,d6 is the 13C- and deuterium labeled Zafirlukast. Zafirlukast (ICI 204219) is a potent orally active leukotriene D4 (LTD4) receptor antagonist. Zafirlukast shows anti-asthmatic, anti-inflammatory and anti-bacterial effects.
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Cat. No.: HY-13448R
CAS No.: 69049-73-6
Synonyms: FPL 59002 (Standard)
Nedocromil (Standard) is the analytical standard of Nedocromil. This product is intended for research and analytical applications. Nedocromil suppresses the action or formation of multiple mediators, including histamine, leukotriene C4 (LTC4), and prostaglandin D2 (PGD2).
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Cat. No.: HY-135336AS1
CAS No.: 1329611-24-6
Synonyms: (S)-(-)-Verapamil-d6 (hydrochloride)
(S)-Verapamil-d6 ((S)-(-)-Verapamil-d6) hydrochloride is the deuterium labeled (S)-Verapamil hydrochloride. (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells .
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Cat. No.: HY-135336AS
CAS No.: 2967473-85-2
Synonyms: (S)-(-)-Verapamil-d7 (hydrochloride)
(S)-Verapamil-d7 (hydrochloride) is a deuterium labeled (S)-Verapamil hydrochloride. (S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells .
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Cat. No.: HY-113693
CAS No.: 103176-67-6
Target:  

Leukotriene Receptor

Research Areas:  

Others

ONO-RS-347 is an orally active and potent antagonist of leukotriene C4 and D4. ONO-RS-347 inhibits LTD4-induced bronchoconstriction in guinea pigs. ONO-RS-347 is promising for research of allergic asthma and other immediate hypersensitivty diseases .
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Cat. No.: HY-W747563
CAS No.: 79768-40-4
Synonyms: 11-trans LTD4
Target:  

Drug Isomer

Research Areas:  

Others

11-trans Leukotriene D4 (11-trans LTD4) is a C-11 double bond isomer of LTD4. LTD4 undergoes slow temperature-dependent isomerization to 11-trans LTD4 during storage. 11-trans LTD4 retains about 10-25 % of the potency for contraction of guinea pig ileum, trachea and parenchyma compared to LTD4. It exhibits an ED50 ranging between 12-60 nM for contraction of guinea pig trachea.
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Cat. No.: HY-W778179
CAS No.: 1329840-53-0
Synonyms: LRCL 3794-13C,d3
Benoxaprofen- 13C, d3 is the 13C-labeled Benoxaprofen (HY-13568). Benoxaprofen (LRCL 3794) is a nonsteroidal anti-inflammatory agent that blocks the biosynthesis of inflammatory mediators such as leukotrienes and prostaglandins by inhibiting 5-LOX, PGH2 synthase and cytochrome P-450. Benoxaprofen exhibits significant toxicity: it not only alters cellular redox status, uncouples oxidative phosphorylation and disrupts calcium ion homeostasis, but also causes liver injury through the formation of covalent adducts between its active metabolites and hepatic proteins. Benoxaprofen shows strong phototoxicity under ultraviolet irradiation, and induces erythrocyte lysis, mast cell degranulation and histamine release. Benoxaprofen is widely used in studies of urticaria and related phototoxic mechanisms .
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Cat. No.: HY-106064
CAS No.: 79672-88-1
Synonyms: U-60257
Piriprost (U-60257) is an inhibitor of Glutathione-S-transferase and leukotriene biosynthesis inhibitor. Piriprost inhibits the biosynthesis of leukotriene C/D without affecting cyclooxygenase-mediated arachidonic acid metabolites. Piriprost increases the activity of alkaline phosphatase (ALP). Piriprost antagonizes contractions induced by leukotriene C/D in vitro. Piriprost is used in asthma research .
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