7 Results for "

long-chain acyl dehydrogenase

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "long-chain acyl dehydrogenase" in MCE Product Catalog:

1
Dodecanoylcarnitine
Dodecanoylcarnitine
0 Images
1 Cited Publications
Cat. No.: HY-113166
CAS No.: 25518-54-1
Purity:  99.75%
Synonyms: (-)-Lauroylcarnitine
Category:  

Immune System Disorder Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

Dodecanoylcarnitine ((-)-Lauroylcarnitine) is a medium long-chain acylcarnitine, an intermediate product in key energy metabolic pathways of fatty acid β-oxidation and amino acids catabolism. The abnormal decrease in the Dodecanoylcarnitine levels indicats that mitochondrial fuel metabolism, including fatty acid oxidation is significantly disturbed. Changes in plasma concentrations of Dodecanoylcarnitine are not only associated with type II diabetes, but also with pre-diabetes status. Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. Dodecanoylcarnitine deomonstrates high sensitivities and specificities in predicting asthma. Combined model of Decanoylcarnitine (HY-113069), Dodecanoylcarnitine, PC (16:0/0:0), and Asp Arg Pro can be used as a potential biomarker for the diagnosis of Yin-deficiency-heat syndrome .
loading...
    loading...
View All Sizes
Tetradecanoylcarnitine
Tetradecanoylcarnitine
0 Images
Cat. No.: HY-113201
CAS No.: 25597-07-3
Purity:  ≥98.0%
Category:  

Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

Tetradecanoylcarnitine is an acylcarnitine involved in mitochondrial β-oxidation of long-chain saturated fatty acids and fatty acid metabolism. Tetradecanoylcarnitine serves as a biomarker for very long-chain acyl-CoA dehydrogenase deficiency and MPTP (HY-15608)-induced Parkinson's disease. Tetradecanoylcarnitine exhibits a characteristic significant elevation in plasma levels in patients with sarcopenia, including those complicated with hypertension, and this elevation is closely associated with an increased risk of death. Tetradecanoylcarnitine is widely used in research on the pathological mechanisms of diseases such as Parkinson's disease and sarcopenia .
loading...
    loading...
View All Sizes
9-Oxononanoic acid
9-Oxononanoic acid
0 Images
Cat. No.: HY-W612338
CAS No.: 2553-17-5
Synonyms: 9-ONA
Category:  

Arachis hypogaea L. Leguminosae Ketones, Aldehydes, Acids Plants

Target:  

Acetyl-CoA Carboxylase

9-Oxononanoic acid (9-ONA) is an orally active acetyl-CoA carboxylase inhibitor. 9-Oxononanoic acid inhibits acetyl-CoA carboxylase via accumulation of long-chain acyl-CoA. 9-Oxononanoic acid increases carnitine palmitoyltransferase, isocitrate dehydrogenase and glucose 6-phosphate dehydrogenase activity to elevate β-oxidation and support NADPH (HY-113324) supplyactivity. 9-Oxononanoic acid stimulates phospholipase A2 activity via post-translational, non-transcriptional mechanisms. 9-Oxononanoic acid can be used for the research of atherothrombosis .
loading...
    loading...
View All Sizes
Heneicosanoyl-CoA
Heneicosanoyl-CoA
0 Images
Cat. No.: HY-E70276
CAS No.: 103404-53-1
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Heneicosanoyl-CoA is a substrate of Very long-chain acyl-CoA dehydrogenase (VLCAD) in the anaerobic electron transfer flavoprotein (ETF) assay .
loading...
    loading...
View All Sizes
Dodecanoylcarnitine (Standard)
Dodecanoylcarnitine (Standard)
0 Images
Cat. No.: HY-113166R
CAS No.: 25518-54-1
Synonyms: (-)-Lauroylcarnitine (Standard)
Category:  

Microorganisms Immune System Disorder Ketones, Aldehydes, Acids Disease markers Endocrine diseases Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite

Dodecanoylcarnitine (Standard) is the analytical standard of Dodecanoylcarnitine (HY-113166). This product is intended for research and analytical applications. Dodecanoylcarnitine ((-)-Lauroylcarnitine) is a medium long-chain acylcarnitine, an intermediate product in key energy metabolic pathways of fatty acid β-oxidation and amino acids catabolism. The abnormal decrease in the Dodecanoylcarnitine levels indicats that mitochondrial fuel metabolism, including fatty acid oxidation is significantly disturbed. Changes in plasma concentrations of Dodecanoylcarnitine are not only associated with type II diabetes, but also with pre-diabetes status. Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. Dodecanoylcarnitine deomonstrates high sensitivities and specificities in predicting asthma. Combined model of Decanoylcarnitine (HY-113069), Dodecanoylcarnitine, PC (16:0/0:0), and Asp Arg Pro can be used as a potential biomarker for the diagnosis of Yin-deficiency-heat syndrome .
loading...
    loading...
View All Sizes
ACADVL/VLCAD Antibody (YA6454)
ACADVL/VLCAD Antibody (YA6454)
0 Images
Cat. No.: HY-P86761
Synonyms: ACAD 6 antibody; ACAD6 antibody; ACADV_HUMAN antibody; Acadvl antibody; acyl CoA dehydrogenase very long chain antibody; acyl Coenzyme A dehydrogenase very long chain antibody; LCACD antibody; mitochondrial antibody; Very long chain specific acyl CoA dehydrogenase antibody; Very long chain specific acyl CoA dehydrogenase mitochondrial antibody; ACAD 6 antibody; ACAD6 antibody; ACADV_HUMAN antibody; Acadvl antibody; acyl CoA dehydrogenase very long chain antibody; acyl Coenzyme A dehydrogenase very long chain antibody; LCACD antibody; mitochondrial antibody; Very long chain specific acyl CoA dehydrogenase antibody; Very long chain specific acyl CoA dehydrogenase mitochondrial antibody; Very long-chain specific acyl-CoA dehydrogenase antibody; VLCAD antibody;

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IF-Tissue, IP

Reactivity:  

Human

loading...
    loading...
View All Sizes
SDZ 51641
SDZ 51641
0 Images
Cat. No.: HY-182438
CAS No.: 91456-99-4
Target:  

Drug Intermediate

Research Areas:  

Metabolic Disease

SDZ 51641 is an orally active fatty acid oxidation inhibitor. By reducing fatty acid oxidation, SDZ 51641 deprives the gluconeogenesis process of required energy and cofactors, thereby lowering blood glucose levels in diabetic models. SDZ 51641 can be used in diabetes research .
loading...
    loading...
View All Sizes
Assay Types