2553-17-5
Chemical Structure
9-Oxononanoic acid
Synonym(s): 9-ONA
- CAS No.: 2553-17-5
- Formula:C9H16O3
- Molecular Weight:172.22
IUPAC Name: 9-oxononanoic acid
InChIKey: WLGDDELKYAWBBL-UHFFFAOYSA-N
SMILES: O=CCCCCCCCC(O)=O
Biological Activity: 9-Oxononanoic acid (9-ONA) is an orally active acetyl-CoA carboxylase inhibitor. 9-Oxononanoic acid inhibits acetyl-CoA carboxylase via accumulation of long-chain acyl-CoA. 9-Oxononanoic acid increases carnitine palmitoyltransferase, isocitrate dehydrogenase and glucose 6-phosphate dehydrogenase activity to elevate β-oxidation and support NADPH (HY-113324) supplyactivity. 9-Oxononanoic acid stimulates phospholipase A2 activity via post-translational, non-transcriptional mechanisms. 9-Oxononanoic acid can be used for the research of atherothrombosis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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9-Oxononanoic acid | 98.29% | 9-Oxononanoic acid (9-ONA) is an orally active acetyl-CoA carboxylase inhibitor. 9-Oxononanoic acid inhibits acetyl-CoA carboxylase via accumulation of long-chain acyl-CoA. 9-Oxononanoic acid increases carnitine palmitoyltransferase, isocitrate dehydrogenase and glucose 6-phosphate dehydrogenase activity to elevate β-oxidation and support NADPH (HY-113324) supplyactivity. 9-Oxononanoic acid stimulates phospholipase A2 activity via post-translational, non-transcriptional mechanisms. 9-Oxononanoic acid can be used for the research of atherothrombosis. | ||||||||||||||||||||
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References
- [1]. Minamoto S, et al. Effect of orally administered 9-oxononanoic acid on lipogenesis in rat liver. Biochim Biophys Acta. 1988;958(2):199-204. [Content Brief]
- [2]. Ren R, et al. A lipid peroxidation product 9-oxononanoic acid induces phospholipase A2 activity and thromboxane A2 production in human blood. J Clin Biochem Nutr. 2013 May;52(3):228-33. [Content Brief]
