2553-17-5
Chemical Structure
9-Oxononanoic acid
Synonym(s): 9-ONA
- CAS No.: 2553-17-5
- Formula:C9H16O3
- Molecular Weight:172.22
IUPAC Name: 9-oxononanoic acid
InChIKey: WLGDDELKYAWBBL-UHFFFAOYSA-N
SMILES: O=CCCCCCCCC(O)=O
Biological Activity: 9-Oxononanoic acid (9-ONA) is an orally active acetyl-CoA carboxylase inhibitor. 9-Oxononanoic acid inhibits acetyl-CoA carboxylase via accumulation of long-chain acyl-CoA. 9-Oxononanoic acid increases carnitine palmitoyltransferase, isocitrate dehydrogenase and glucose 6-phosphate dehydrogenase activity to elevate β-oxidation and support NADPH (HY-113324) supplyactivity. 9-Oxononanoic acid stimulates phospholipase A2 activity via post-translational, non-transcriptional mechanisms. 9-Oxononanoic acid can be used for the research of atherothrombosis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
9-Oxononanoic acid | 98.29% | 9-Oxononanoic acid (9-ONA) is an orally active acetyl-CoA carboxylase inhibitor. 9-Oxononanoic acid inhibits acetyl-CoA carboxylase via accumulation of long-chain acyl-CoA. 9-Oxononanoic acid increases carnitine palmitoyltransferase, isocitrate dehydrogenase and glucose 6-phosphate dehydrogenase activity to elevate β-oxidation and support NADPH (HY-113324) supplyactivity. 9-Oxononanoic acid stimulates phospholipase A2 activity via post-translational, non-transcriptional mechanisms. 9-Oxononanoic acid can be used for the research of atherothrombosis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.95
HY-W612387Suberaldehydic acid -
Similarity Score 0.91
HY-W2656447-Oxoheptanoic acid -
Similarity Score 0.89
HY-16585412-Oxo-9(Z)-dodecenoic acid -
Similarity Score 0.89
HY-W1604079-Decenoic acid -
Similarity Score 0.86
HY-W1291478-Hydroxyoctanoic acid -
Similarity Score 0.86
HY-B091410-Undecenoic acid,98% (stabilized with TBC) -
Similarity Score 0.86
HY-W018678R8-Aminooctanoic acid (Standard) -
Similarity Score 0.86
HY-W0077008-Bromooctanoic acid -
Similarity Score 0.86
HY-N7057ANonanoic acid ammonium -
Explore the MedChemAI to find more analogs
References
- [1]. Minamoto S, et al. Effect of orally administered 9-oxononanoic acid on lipogenesis in rat liver. Biochim Biophys Acta. 1988;958(2):199-204. [Content Brief]
- [2]. Ren R, et al. A lipid peroxidation product 9-oxononanoic acid induces phospholipase A2 activity and thromboxane A2 production in human blood. J Clin Biochem Nutr. 2013 May;52(3):228-33. [Content Brief]
