Search Result
Results for "
maleimides
" in MedChemExpress (MCE) Product Catalog:
175
Biochemical Assay Reagents
5
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-144004
-
|
DSPE-PEG2000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] ammonium
|
Liposome
|
Others
|
|
DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents .
|
-
-
- HY-140739
-
|
|
Liposome
|
Neurological Disease
Cancer
|
|
DSPE-PEG2000-Maleimide sodium (purity>95%) is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide sodium (purity>95%) can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration .
|
-
-
- HY-138200
-
|
Cyanine5 maleimide
|
DNA Stain
Fluorescent Dye
|
Others
|
|
Cy5 maleimide (Cyanine5 maleimide) is a single-reactive dye containing a maleimide group and a CY5 fluorescent group, which can selectively couple with a thiol group. Cy5 maleimide can be used to label antibodies, peptides, or proteins (Ex/Em = 646/664 nm).
|
-
-
- HY-120770
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-PEG4-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
-
- HY-D0098
-
|
N-(5-Fluoresceinyl)maleimide
|
Fluorescent Dye
|
Others
|
Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .
|
-
-
- HY-D0069
-
|
|
Fluorescent Dye
|
Others
Cancer
|
|
CPM is a maleimide derivative, acting as a blue fluorescent thiol-reactive dye (excitation/emission maxima of 387/463 nm) .
|
-
-
- HY-166648
-
|
|
Liposome
|
Cancer
|
|
DSPE-PEG2000-Maleimide sodium (purity>99%) is a functional lipid component and a thiol-reactive crosslinker. DSPE-PEG2000-Maleimide sodium (purity>99%) undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG2000-RGD. DSPE-PEG2000-Maleimide sodium (purity>99%) is applicable to research on drug delivery .
|
-
-
- HY-140740
-
|
|
Liposome
|
Others
|
|
DSPE-PEG5000-Maleimide, is a linker lipid containing DSPE phospholipid and Maleimide. DSPE-PEG-Maleimide is used in the synthesis of liposomes, including HELDC liposomes, sterically stabilized liposomes, and immunoliposomes .
|
-
-
- HY-144004A
-
|
DSPE-PEG5000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-5000] ammonium
|
Liposome
|
Others
|
|
DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents . DSPE-PEG5000-Mal ammonium contains PEG5000.
|
-
-
- HY-151696
-
|
|
ADC Linker
|
Others
|
|
TCO-PEG3-maleimide (TCO-PEG3-NEM) is a click chemistry reagent. TCO-PEG3-maleimide efficiently binds TCO (trans-cyclooctene) moiety to thiol-containing molecules (such as antibodies, cysteine-containing peptides) .
|
-
-
- HY-168940B
-
|
|
Drug Intermediate
|
Cancer
|
|
NH2-PEG2000-COOH is a heterofunctional polyethylene glycol with one amino terminal group and one carboxyl terminal group. NH2-PEG2000-COOH reacts with N-succinimidyl-6-maleimidohexanoate to introduce a maleimide terminal group, followed by conjugation with thiolated RGD peptide via a thiol-maleimide coupling reaction to synthesize RGD-PEG-COOH. NH2-PEG2000-COOH can be used in cancer research .
|
-
-
- HY-156311
-
|
|
ADC Linker
|
Cancer
|
|
BCN-endo-PEG2-maleimide is an ADC Linker containing 4 PEG units. BCN-endo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
-
- HY-157977
-
|
|
Biochemical Assay Reagents
Radionuclide-Drug Conjugates (RDCs)
MMP
|
Cancer
|
|
DOTA-GA-maleimide is a bifunctional chelator with protein conjugation and radiometal chelation capabilities. DOTA-GA-maleimide forms stable complexes with 111In and conjugates with proteins via maleimide chemistry. DOTA-GA-maleimide conjugates with LFn, enabling 111In radiolabeling of LFn through direct or pre-labeling strategies. Radiolabeled LFn is applicable to MMP activity imaging studies. DOTA-GA-maleimide is used in cancer research .
|
-
-
- HY-141278
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG4-maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
-
- HY-W011618
-
|
|
Fluorescent Dye
|
Others
|
|
N-(9-Acridinyl)maleimide is a maleimide type fluorescent thiol reagent. N-(9-Acridinyl)maleimide shows no substantial fluorescence but its coupling products with thiol compounds exhibit strong blue fluorescence. N-(9-Acridinyl)maleimide is used for fluorometrical analysis of cysteine and glutathione .
|
-
-
- HY-W441004
-
|
|
Liposome
|
Others
|
|
DSPE-Thiol is a phophalipid capped with thiol group. The thiol capped head can selectively react with maleimide. DSPE-Thiol can also be used for the preparation of phospholipid dimers .
|
-
-
- HY-155640
-
|
|
Fluorescent Dye
|
Others
|
|
Maleimide-5’FAM is a fluorescein. Maleimide-5’FAM can be used for labeling non-transduced cells .
|
-
-
- HY-134734
-
|
|
ADC Linker
|
Cancer
|
|
BCN-exo-PEG7-maleimide is an ADC Linker containing 7 PEG units. BCN-exo-PEG7-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
-
- HY-133399
-
|
|
PROTAC Linkers
|
Cancer
|
|
Alkyne-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Alkyne-PEG4-maleimide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
-
- HY-140307
-
|
|
PROTAC Linkers
|
Cancer
|
|
Sulfo DBCO-PEG4-Maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Sulfo DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
-
- HY-137098
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy3 maleimide potassium is a fluorescent dye with a maleimide functionality at the end a short alkyl linker. Sulfo-Cy3 maleimide potassium can be used for the labeling of antibodies and other labile proteins .
|
-
-
- HY-W879048
-
|
|
ADC Linker
|
Others
|
|
DBCO-PEG24-Maleimide contains a maleimide and a DBCO group. DBCO-PEG24-Maleimide can be used for thiol-containing biomolecule conjugations. DBCO-PEG24-Maleimide can be used in click chemistry with azide-bearing biomolecules .
|
-
-
- HY-W441009A
-
|
|
Liposome
|
Others
|
|
DSPE-PEG3400-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG3400-Maleimide ammonium can be used in drug delivery research .
|
-
-
- HY-W190932
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA-PEG2-Maleimide is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG2-Maleimide contains a maleimide group that can react with a thiol group to form a covalent bond.
|
-
-
- HY-W1048661E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG2000-maleimide is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG2000-maleimide anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
-
- HY-156377
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Biotin-PEG7-Maleimide is a biotinylation reagent that reacts with thiol groups (SH). Biotin-PEG7-Maleimide can be used as Drug-Linker Conjugates for ADCs .
|
-
-
- HY-D1364
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Pyrene maleimide is a polyaromatic fluorescent hydrocarbon with a termininal maleimide group. The maleimide group will react with a thiol group to form a covalent bond.
|
-
-
- HY-D1566
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
-
- HY-W872575
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO4-PEG3-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG3-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
|
-
-
- HY-156322
-
|
|
ADC Linker
|
Cancer
|
|
BCN-exo-PEG3-maleimide is an ADC Linker containing 3 PEG units. BCN-exo-PEG3-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which enables the further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
-
- HY-D2498
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7 maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides .
|
-
-
- HY-133374
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-PEG12-Maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG12-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
-
- HY-D2187
-
|
|
Fluorescent Dye
|
Others
|
|
6-TAMRA maleimide is a fluorescent dye composed of the fluorescent group of an avidin derivative and a maleimide group.
|
-
-
- HY-W441009B
-
|
|
Liposome
|
Others
|
|
DSPE-PEG1000-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG1000-Maleimide ammonium can be used in drug delivery research .
|
-
-
- HY-N16290
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Chol-PEG2000-maleimide is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
-
- HY-156320
-
|
|
ADC Linker
|
Cancer
|
|
BCN-exo-PEG2-maleimide is an ADC Linker containing 2 PEG units. BCN-exo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
-
- HY-W1048851B
-
|
4-Arm-PEG10000-Mal
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG10000-Maleimide (4-Arm-PEG10000-Mal) is a four-arm star-shaped multifunctional PEG crosslinker with an average molecular weight of 10 kDa and maleimide terminal groups. 4-Arm-PEG10000-Maleimide efficiently conjugates biomolecules via thiol-Michael reaction, and is widely used in protein modification, antibody-drug conjugation and biomaterial preparation .
|
-
-
- HY-D2488
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy5.5-maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides.
|
-
-
- HY-156308
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG4-Maleimide is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
-
- HY-156392
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO4-PEG7-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG7-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
|
-
-
- HY-164785
-
|
|
Drug Intermediate
|
Others
|
|
TCO-PEG5-maleimide is a PEG linker with TCO and maleimide groups, specifically enabling tetrazine click chemistry and thiol conjugation for bioconjugation, probe design, and drug delivery.
|
-
-
- HY-W879049
-
|
DBCO-NHCO-PEG3-maleimide
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG3-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG3-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
|
-
-
- HY-N15976
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-pSar25 Maleimide is a lipid conjugated to DMG, Maleimide and pSar25 polymer. DMG-pSar25 Maleimide can be used to prepare lipid nanoparticles for drug delivery.
|
-
-
- HY-115756
-
|
|
Others
|
Others
|
|
4-Maleimidosalicylic acid is a polar maleimide, and does not suppress IL-2 production in JURKAT T cells .
|
-
-
- HY-D2182
-
|
|
Fluorescent Dye
|
Others
|
|
Preactivated PE-Cy5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.
|
-
-
- HY-D2180
-
|
|
Fluorescent Dye
|
Others
|
|
Preactivated APC-Cy5.5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.
|
-
-
- HY-140739A
-
|
|
Liposome
|
Neurological Disease
Cancer
|
|
DSPE-PEG2000-Maleimide free acid is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide free acid utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide free acid covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide free acid can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration .
|
-
-
- HY-W1048661A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG5000-maleimide is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG5000-maleimide anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
-
- HY-W1048661
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG1000-maleimide is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG1000-maleimide anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
-
- HY-D1592
-
|
|
Fluorescent Dye
|
Others
|
|
BODIPY TMR C5-maleimide is a fluorescent dye. BODIPY TMR C5-maleimide is a high quantum yield fluorophore which can be coupled with peptides .
|
-
- HY-N16291
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSG-pSar25-Maleimide is a lipid that is composed of a DSG unit conjugated to a pSar25 polymer. DSG-pSar25-Maleimide can be used to prepare lipid nanoparticles for drug delivery.
|
-
- HY-156307
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG3-Maleimide is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-156312
-
|
|
ADC Linker
|
Cancer
|
|
Me-Tet-PEG8-Maleimide is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-174927E
-
|
DBCO-PEG3400-Mal
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG3400-Maleimide (DBCO-PEG3400-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG3400-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927B
-
|
DBCO-PEG600-Mal
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG600-Maleimide (DBCO-PEG600-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG600-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927A
-
|
DBCO-PEG400-Mal
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG400-Maleimide (DBCO-PEG400-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG400-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927D
-
|
DBCO-PEG2000-Mal
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG2000-Maleimide (DBCO-PEG2000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG2000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927H
-
|
DBCO-PEG10000-Mal
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG10000-Maleimide (DBCO-PEG10000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG10000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174885B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Acrylate-PEG3400-Maleimide is a PEG derivative containing an acrylate functional group, a PEG chain, and a maleimide group, which can be used for drug delivery .
|
-
- HY-D0152
-
|
|
Fluorescent Dye
|
Others
|
|
Tetramethylrhodamine-6-maleimide is a fluorescent dye with a reactive sulfhydryl-specific moiety is covalently coupled to this cysteine. Tetramethylrhodamine-6-maleimide can be used as labels to detect local protein motions of the fully active Na+/K+-ATPase in real time .
|
-
- HY-W879036
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG8-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG8-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
|
-
- HY-W016550
-
|
CHMI; NCMI; NSC 524431
|
Biochemical Assay Reagents
|
Others
|
|
N-Cyclohexylmaleimide is a compound containing a maleimide group, and this maleimide group can react with NHS ester.
|
-
- HY-133475
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG5-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG5-maleimide is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-151940
-
|
|
Reactive Oxygen Species (ROS)
|
Cancer
|
|
Mal-Pc is a versatile molecular photosensitizer designed based phthalocyanine and maleimides. Mal-Pc can react with GSH to deplete GSH and reduce aggregation, thereby improving ROS (Reactive Oxygen Species)-mediated effect of photodynamic therapy (PDT) in cancer cells .
|
-
- HY-159674
-
|
N-Tetamine-polySarcosine45-Maleimide
|
Biochemical Assay Reagents
|
Others
|
|
N-Tetamine-pSar45-Maleimide (N-Tetamine-polySarcosine45-Maleimide) is a pSar-lipid derivative. As a hydrophilic alternative to PEG, N-Tetamine-pSar45-Maleimide can be used in drug delivery research .
|
-
- HY-W441009C
-
|
|
Liposome
|
Others
|
|
DSPE-PEG4000-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG4000-Maleimide ammonium can be used in drug delivery research .
|
-
- HY-W441009H
-
|
|
Liposome
|
Others
|
|
DSPE-PEG40000-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG40000-Maleimide ammonium can be used in drug delivery research .
|
-
- HY-W441009D
-
|
|
Liposome
|
Others
|
|
DSPE-PEG10000-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG10000-Maleimide ammonium can be used in drug delivery research .
|
-
- HY-D2103
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA-PEG3-Maleimide is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Maleimide contains maleimide groups that react with thiol groups to form covalent bonds.
|
-
- HY-D2104
-
|
|
Fluorescent Dye
|
Others
|
|
TAMRA-PEG7-Maleimide is a dye derivative of TAMRA (HY-135640) containing 7 PEG units. TAMRA-PEG7-Maleimide contains a maleimide group that can react with a thiol group to form a covalent bond.
|
-
- HY-W540192
-
|
|
ADC Linker
|
Cancer
|
|
SCO-PEG2-Maleimide is an ADC Linker containing 3 PEG units. SCO-PEG2-Maleimide can be used as a copper-free click chemical reagent for catalyst-free click reactions. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-156318
-
|
|
ADC Linker
|
Cancer
|
|
SCO-PEG3-Maleimide is a cleavable ADC Linker containing 3 PEG units. SCO-PEG3-Maleimide can be used as a copper-free click chemical reagent for catalyst-free click reactions. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-156321
-
|
|
ADC Linker
|
Cancer
|
|
SCO-PEG7-Maleimide is a cleavable ADC Linker containing 3 PEG units. SCO-PEG7-Maleimide can be used as a copper-free click chemical reagent for catalyst-free click reactions. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-W1048661H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG3400-maleimide is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG3400-maleimide anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
- HY-157919
-
|
N-6-(Biotinylamino)hexanoyl-N'-[2-(N-maleimido)ethyl]piperazine, hydrochloride
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEAC5-maleimide hydrochloride is a biochemical assay reagent, and can be used in biotin-PEAC5-maleimide (BPM)-labeling assay to assess modification of protein thiols by electrophiles .
|
-
- HY-N16237
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Chol-PEG1000-maleimide is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-W739513
-
-
- HY-156391
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO4-PEG2-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG2-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
|
-
- HY-W872575A
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO4-PEG3-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG3-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
|
-
- HY-156391A
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO4-PEG2-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG2-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
|
-
- HY-174927
-
|
DBCO-PEG5000-Mal
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG5000-Maleimide (DBCO-PEG5000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG5000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927C
-
|
DBCO-PEG1000-Mal
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG1000-Maleimide (DBCO-PEG1000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG1000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-W800817
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TCO-PEG4-maleimide is a click chemistry building block containing a TCO moiety and a maleimide group. The maleimide group will react with a thiol group to form a covalent bond. TCO moiety is very reactive with tetrazine (3rd generation click chemistry).
|
-
- HY-174885C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Acrylate-PEG5000-Maleimide is a PEG derivative containing an acrylate functional group, a PEG chain, and a maleimide group, which can be used for drug delivery .
|
-
- HY-174885
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Acrylate-PEG1000-Maleimide is a PEG derivative containing an acrylate functional group, a PEG chain, and a maleimide group, which can be used for drug delivery .
|
-
- HY-174885A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Acrylate-PEG2000-Maleimide is a PEG derivative containing an acrylate functional group, a PEG chain, and a maleimide group, which can be used for drug delivery .
|
-
- HY-168938
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Poly(ethylene glycol) methyl ether maleimide (Mn 2000) is a polyethylene glycol containing Maleimide (HY-W007324). Due to the Maleimide functional group, Poly(ethylene glycol) methyl ether maleimide (Mn 2000) can be used to conjugate biomolecules containing thiol groups.
|
-
- HY-157008
-
|
|
ADC Linker
|
Cancer
|
|
(S)-TCO-PEG2-Maleimide is an ADC linker containing 2 PEG units. (S)-TCO-PEG2-Maleimide can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-D0151
-
|
|
Fluorescent Dye
|
Others
|
|
Tetramethylrhodamine-5-maleimide is a fluorescent probe with high specificity for cysteine thiol (SH) groups. Tetramethylrhodamine-5-maleimide has high sensitivity, responds rapidly to negatively charged nanoparticles, and shows a concentration-dependent decrease in fluorescence intensity, but it is susceptible to interference from humic acids .
|
-
- HY-D0103
-
|
|
Fluorescent Dye
|
|
|
Fluorescein diacetate 5-maleimide is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.
|
-
- HY-171561
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOTAM-Maleimide triTFA is a bifunctional chelator, combining the DOTAM structure with a maleimide group for efficient thiol coupling. DOTAM-Maleimide triTFA forms stable complexes with radiometals, promising for applications in molecular imaging and radiotherapy .
|
-
- HY-133372
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-NHCO-PEG2-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG2-maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133373
-
|
|
PROTAC Linkers
|
Cancer
|
|
DBCO-NHCO-PEG6-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG6-maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133468
-
|
|
PROTAC Linkers
|
Cancer
|
|
Methyltetrazine-PEG6-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG6-maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-W441009E
-
|
|
Liposome
|
Others
|
|
DSPE-PEG20000-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG20000-Maleimide ammonium can be used in drug delivery research .
|
-
- HY-DY1088
-
|
N-(5-Fluoresceinyl)maleimide (solution)
|
Fluorescent Dye
|
Others
|
Fluorescein-5-maleimide (solution) (N-(5-Fluoresceinyl)maleimide (solution)) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .
Solvent and concentration: DMSO: 10 mM
|
-
- HY-186000
-
|
|
Drug Derivative
|
Cancer
|
|
Paclitaxel-maleimide is Paclitaxel (HY-B0015) modified with a maleimide linker. Paclitaxel-maleimide shows strong BSA binding ability. Paclitaxel-maleimide can be used in tumor research .
|
-
- HY-D3270
-
|
|
Fluorescent Dye
|
Others
|
|
IR 750 Maleimide is a near-infrared fluorescent dye composed of IRDye 750 near-infrared fluorophore and maleimide reactive group. IR 750 Maleimide can be applied to fluorescent labeling, imaging and detection.
|
-
- HY-D2932
-
|
SNAP-Maleimide
|
Biochemical Assay Reagents
|
Others
|
|
BG-maleimide is a building block. BG-maleimide allows the attachment of Benzylguanine to thiolcontaining precursors .
|
-
- HY-W007324R
-
|
|
Reference Standards
ADC Linker
Biochemical Assay Reagents
|
Cancer
|
|
Maleimide (Standard) is the analytical standard of Maleimide (HY-W007324). This product is intended for research and analytical applications. Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes .
|
-
- HY-W998680
-
|
5-FITC-Maleimide
|
Fluorescent Dye
|
Others
|
|
Fluorescein-maleimide (5-FITC-Maleimide) is a thiol-reactive fluorescent derivatization reagent and non-specific protein labeling reagent. Fluorescein-maleimide covalently binds to protein thiol groups for protein labeling. Fluorescein-maleimide covalently binds to protein amino and imidazole groups under neutral pH conditions. Fluorescein-maleimide is used for fluorescent labeling of proteins, nucleic acids or other molecules containing one or more thiol groups (Ex/Em = 494/519 nm) .
|
-
- HY-140307A
-
|
|
PROTAC Linkers
|
Others
|
|
Sulfo DBCO-PEG4-Maleimide TEA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Sulfo DBCO-PEG4-Maleimide (TEA) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133477
-
|
|
PROTAC Linkers
|
Cancer
|
|
(S)-TCO-PEG3-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . (S)-TCO-PEG3-maleimide is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-P11697
-
|
|
Drug Intermediate
|
Others
|
|
Fmoc-PNA-maleimide-OH is a Fmoc-protected functionalized peptide nucleic acid monomer featuring a maleimide group for thiol-reactive conjugation. Fmoc-PNA-maleimide-OH can be used in constructing PNA conjugates for molecular assembly applications.
|
-
- HY-D3252
-
|
|
Fluorescent Dye
|
Others
|
|
IR 650 maleimide is a near-infrared fluorescent dye. It should be noted that IR 650 maleimide‘s fluorescence stability is poor, with less than 16% of the fluorescence signal retained after the expansion microscopy experimental procedure .
|
-
- HY-D1340
-
|
|
Fluorescent Dye
|
|
|
Sulfo-Cyanine7 maleimide potassium is an analogue of Cy7 maleimide and a hydrophilic near-infrared fluorescent dye.
|
-
- HY-141184
-
|
|
PROTAC Linkers
|
Cancer
|
|
TCO-PEG9-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-171561G
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOTAM-Maleimide triTFA (GMP) is DOTAM-Maleimide triTFA (HY-171561) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOTAM-Maleimide triTFA is a bifunctional chelator .
|
-
- HY-131029
-
|
JF646, Maleimide
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor® 646, Maleimide (JF646, Maleimide) is a red fluorescent dye that contains a maleimide group. JF646, Maleimide can be used in cellular imaging . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-W800786
-
|
N-MCC-PE
|
Liposome
|
Cancer
|
|
16:0 PE MCC is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two palmitic acid tails and a maleimide group.
|
-
- HY-156488
-
-
- HY-W800787
-
|
|
Liposome
|
Cancer
|
|
18:1 PE MCC is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two oleic acid tails and a maleimide group.
|
-
- HY-156317
-
|
|
ADC Linker
|
Cancer
|
|
BCN-endo-PEG7-maleimide is an ADC Linker containing 7 PEG units. BCN-endo-PEG7-maleimide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
-
- HY-D2091
-
|
|
Fluorescent Dye
|
Others
|
|
PE-VF647 Maleimide is a double-dye dye that can undergo thiol reaction. It contains maleimide groups that can react with thiol groups to form covalent bonds. PE-VF647 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 665 nm.
|
-
- HY-A0023AS2
-
-
- HY-W800789
-
|
|
Liposome
|
Cancer
|
|
16:0 MPB PE is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two palmitic acid tails and a phenyl maleimide group.
|
-
- HY-W097734
-
-
- HY-W800788
-
|
|
Liposome
|
Cancer
|
|
18:1 MPB PE is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two oleic acid tails and a phenyl maleimide group.
|
-
- HY-175614
-
|
|
Drug-Linker Conjugates for ADC
Glutathione Peroxidase
Ferroptosis
|
Cancer
|
|
RSL3-NH2-Ala-Val-DBCO-PEG4-Maleimide is a drug-linker conjugate for ADC. RSL3-NH2-Ala-Val-DBCO-PEG4-Maleimide consists of a GPX4 inhibitor and ferroptosis inducer (RSL3-NH2) (HY-175615) and a linker (H-Ala-Val-OH) (HY-P4955). RSL3-NH2-Ala-Val-DBCO-PEG4-Maleimide can be used for synthesis of ADCs .
|
-
- HY-W017588
-
-
- HY-N16289
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG8 Maleimide sodium is a PEG lipid containing DSPE, a polyethylene glycol chain consisting of eight ethylene glycol units (PEG8), and a maleimide group (Mal). DSPE-PEG8 Maleimide sodium can be used to prepare lipid nanoparticles for drug delivery .
|
-
- HY-D2093
-
|
|
Fluorescent Dye
|
Others
|
|
PE-VF750 Maleimide is a thiol-reactive double-dye dye that contains maleimide groups that can react with thiol groups to form covalent bonds. Ex/Em=495-566/777 nm. PE-VF750 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 777 nm.
|
-
- HY-D1925
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 425 Maleimide is a maleimide ester derivative of ATTO 425, which can be used to label proteins or antibodies. The maximum excitation emission wavelength: 439/489 nm.
|
-
- HY-D1918
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 390 maleimide is a maleimide ester derivative of ATTO 390, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 390/476 nm.
|
-
- HY-D3052
-
|
|
Fluorescent Dye
|
Others
|
|
5(6)-carbonylated rhodamine 110 maleimide is a maleimide-based fluorescent reagent based on 5(6)-carbonylated rhodamine 110. Maleimide can be labeled by forming a stable thioester structure through an affinity addition reaction with a thiol group (-SH) (Ex/Em = 502/527 nm).
|
-
- HY-D2092
-
|
|
Fluorescent Dye
|
Others
|
|
PE-VF680 Maleimide is a double-dye dye that can undergo thiol reaction. It contains maleimide groups that can react with thiol groups to form covalent bonds. Ex/Em=495-566/701 nm. PE-VF680 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 701 nm.
|
-
- HY-D3291
-
|
|
Fluorescent Dye
|
Others
|
|
IR 680LT Maleimide is a near-infrared low-band fluorescence dye, composed of the IR 680LT dye core and maleimide groups. IR 680LT Maleimide is used for specifically labeling biologically active molecules containing sulfhydryl groups (Ex/Em = 679 nm/694 nm).
|
-
- HY-D2150
-
|
|
Fluorescent Dye
|
Others
|
|
AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 maleimide contains maleimide groups that react with thiol groups to form covalent bonds. To achieve specific coupling of dye labels and biomolecules .
|
-
- HY-D3056
-
|
|
Fluorescent Dye
|
Others
|
|
5(6)-Rhodamine 6G maleimide is a maleimide-based fluorescent reagent based on Rhodamine 6G (HY-D0309). Maleimide can be labeled by forming a stable thioester structure through an affinity addition reaction with a thiol group (-SH) (Ex/Em = 526/547 nm).
|
-
- HY-W1048851A
-
|
4-Arm-PEG5000-Mal
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG5000-Maleimide can be used for site-specific protein and peptide modification and can be used for drug delivery .
|
-
- HY-W1048851D
-
|
4-Arm-PEG40000-Mal
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG40000-Maleimide can be used for site-specific protein and peptide modification and can be used for drug delivery .
|
-
- HY-W1048851C
-
|
4-Arm-PEG20000-Mal
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG20000-Maleimide can be used for site-specific protein and peptide modification and can be used for drug delivery .
|
-
- HY-174921B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Maleimide-PEG3400-COOH is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
|
-
- HY-174921C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Maleimide-PEG5000-COOH is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
|
-
- HY-174921
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Maleimide-PEG1000-COOH is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
|
-
- HY-174921A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Maleimide-PEG2000-COOH is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
|
-
- HY-W738256
-
|
MDTPA
|
Radionuclide-Drug Conjugates (RDCs)
|
Cancer
|
|
Maleimide-DTPA (MDTPA) is a monoreactive DTPA derivative (MDTPA) with maleimide group as peptide binding site, which can be combined with radionuclides to prepare radionuclide conjugates (RDC). Maleimide-DTPA can chelate indium-111 (111In) and label peptides and peptides with indium-111. For example, it has high stability when combined with OST7 incubated in human serum, which is better than cyclic cDTPA. Maleimide-DTPA is a good material for medical imaging or treatment.
|
-
- HY-W808757
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-maleimide is a biotinylated biochemical detection reagent that acts as a thiol-specific probe. Biotin-maleimide can also be used to prepare biotin-conjugated polychelators .
|
-
- HY-133540G
-
|
Maleimido-mono-amide-DOTA
|
ADC Linker
|
Inflammation/Immunology
Cancer
|
|
Maleimide-DOTA (Maleimido-mono-amide-DOTA) (GMP) is Maleimide-DOTA (HY-133540) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-D2002
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 488 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 maleimide is a maleimide derivative of ATTO 488, which can be used to label proteins or antibodies.
|
-
- HY-D2047
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 532 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 maleimide is a maleimide derivative of ATTO 532, which can be used to label proteins or antibodies.
|
-
- HY-D2063
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 740 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 740 maleimide is a maleimide derivative of ATTO 740, which can be used to label proteins or antibodies.
|
-
- HY-D1933
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 590 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 maleimide is a maleimide derivative of ATTO 590, which can be used to label proteins or antibodies.
|
-
- HY-D2059
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 700 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 700 maleimide is a maleimide derivative of ATTO 700, which can be used to label proteins or antibodies.
|
-
- HY-D2074
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 680 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 680 maleimide is a maleimide derivative of ATTO 680, which can be used to label proteins or antibodies.
|
-
- HY-D2021
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 550 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 maleimide is a maleimide derivative of ATTO 550, which can be used to label proteins or antibodies.
|
-
- HY-D1961
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 565 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 maleimide is a maleimide derivative of ATTO 565, which can be used to label proteins or antibodies.
|
-
- HY-D1546
-
|
|
Fluorescent Dye
|
Cancer
|
|
Biotin-C2-maleimide is an antibody conjugate reagent, can bind to many biomolecules without significantly changing the biological activity of the target molecule .
|
-
- HY-174961B
-
|
Fmoc-NH-PEG3400-Mal
|
Biochemical Assay Reagents
|
Others
|
|
Fmoc-PEG3400-Maleimide (Fmoc-NH-PEG3400-Mal) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-D1871
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3 maleimide chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing maleimide functional groups. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The alkyne functional group of Cy3 maleimide chloride can undergo a "thiol-acrylamide" reaction with molecules containing sulfur-oxygen functional groups to form covalent bonds. Cy3 maleimide chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-174961
-
|
Fmoc-NH-PEG1000-Mal
|
Biochemical Assay Reagents
|
Others
|
|
Fmoc-PEG1000-Maleimide (Fmoc-NH-PEG1000-Mal) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-W087027
-
|
|
Radionuclide-Drug Conjugates (RDCs)
Biochemical Assay Reagents
Integrin
|
Cancer
|
|
Maleimide-NOTA is a chelate. Maleimide-NOTA can be site-specifically coupled to the hPD-L1 nanobody bearing the Cys-tag. Maleimide-NOTA can specifically conjugate to A20FMDV2 (HY-P1654). The [ 68Ga]Ac-CG6 formed by the conjugation of 68Ga radiolabeled Maleimide-NOTA with A20FMDV2 can be used for PET imaging of αvβ6 integrin-positive pancreatic ductal adenocarcinoma .
|
-
- HY-174961C
-
|
Fmoc-NH-PEG5000-Mal
|
Biochemical Assay Reagents
|
Others
|
|
Fmoc-PEG5000-Maleimide (Fmoc-NH-PEG5000-Mal) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-174961A
-
|
Fmoc-NH-PEG2000-Mal
|
Biochemical Assay Reagents
|
Others
|
|
Fmoc-PEG2000-Maleimide (Fmoc-NH-PEG2000-Mal) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-W087027A
-
-
- HY-W591618D
-
|
4-Arm-PEG3400-Mal
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG3400-Maleimide (4-Arm-PEG3400-Mal) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-W591465
-
|
4-Arm-PEG2000-Mal
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG2000-Maleimide (4-Arm-PEG2000-Mal) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-W591618A
-
|
4-Arm-PEG400-Mal
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG400-Maleimide (4-Arm-PEG400-Mal) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-W591618B
-
|
4-Arm-PEG600-Mal
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG600-Maleimide (4-Arm-PEG600-Mal) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-W591618C
-
|
4-Arm-PEG1000-Mal
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm-PEG1000-Maleimide (4-Arm-PEG1000-Mal) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-D1618
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine3 maleimide tetrafluoroborate is a specific labeling reagent for sulfhydryl groups with the λex of 550 nm and λem of 580 nm. Cyanine3 maleimide tetrafluoroborate can be used for protein and peptide labeling .
|
-
- HY-148549
-
-
- HY-174941
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG18-acid is a PEG derivative modified with maleimide groups. Maleimide is a functional group that can undergo Michael addition reaction with sulfhydryl (–SH) groups and can be used for bioconjugation.
|
-
- HY-D2231
-
|
|
ADC Payload
|
Others
|
|
Cy3.5 maleimide is a relatively water-soluble fluorescent dye. Cy3.5 maleimide is soluble in organic solvents, including DMF, DMSO and acetonitrile and so on .
|
-
- HY-D1351
-
|
Sulfo-Cy5.5 maleimide potassium
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cyanine5.5 maleimide (Sulfo-Cy5.5 maleimide) potassium is a fluorescent dye. Sulfo-Cyanine5.5 is a nearinfrared (NIR) fluorophore with excitation maximum 675 nm and emission maximum 694 nm. Sulfo-Cyanine5.5 maleimide potassium can be used for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers .
|
-
- HY-D1869
-
|
|
Fluorescent Dye
|
Others
|
|
800CW maleimide is an infrared dye that can be used for labeling molecules that contain free sulfhydryl (–SH) groups (Ex: 778 nm; Em: 796 nm). 800CW maleimide binds to plasma proteins .
|
-
- HY-W440718C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Cholesterol-PEG10000-Mal is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-46225
-
|
|
Drug Intermediate
|
Inflammation/Immunology
|
|
DEX-maleimide is a coupling agent that can be used to synthesize conjugates containing single-domain antibodies (VHH) conjugated with antigens and anti-inflammatory agents. DEX-maleimide can be used for research on autoimmune diseases .
|
-
- HY-D2249
-
-
- HY-174953D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TPP-PEG10000-Mal is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-W007324
-
|
|
ADC Linker
Biochemical Assay Reagents
|
Cancer
|
|
Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes .
|
-
- HY-D2181
-
|
|
Fluorescent Dye
|
Others
|
|
Preactivated PE-Cy5.5 Maleimide is a Preactivated PE-Cy5.5 Maleimide, which is a dye that can be used to label molecules such as dye that can be used to label molecules such as antibodies .
|
-
- HY-174953
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TPP-PEG1000-Mal is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-W190746
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG1-Mal is a PEG derivative with maleimide groups at both ends. Maleimide is a functional group that can undergo Michael addition reactions with sulfhydryl groups (–SH) and can be used for bioconjugation .
|
-
- HY-174953B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TPP-PEG3400-Mal is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-174953A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TPP-PEG2000-Mal is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-174953C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
TPP-PEG5000-Mal is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-W190755
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG4-Mal is a PEG derivative with maleimide groups at both ends. Maleimide is a functional group that can undergo Michael addition reactions with sulfhydryl groups (–SH) and can be used for bioconjugation .
|
-
- HY-161780
-
|
|
Drug-Linker Conjugates for ADC
CDK
|
Cancer
|
|
Maleimide-Val-Ala-PAB-SNS032 is a conjugate of ADC toxin and linker. SNS032 is an inhibitor for CDK, inhibiting the cell cycle at G1/S phase and cell viability of cancer cells. Maleimide-Val-Ala-PAB is a cleavable ADC linker. Maleimide-Val-Ala-PAB-SNS032 can be utilized for the synthesis of ADC molecules .
|
-
- HY-166648A
-
|
|
Liposome
|
Others
|
|
DSPE-PEG-Maleimide ammonium (MW 2000) is a functional lipid component and a thiol-reactive crosslinker. DSPE-PEG-Maleimide ammonium (MW 2000) undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG (2000)-RGD. DSPE-PEG-Maleimide ammonium (MW 2000) is applicable to research on drug delivery .
|
-
- HY-W1048555B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG3400-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG3400-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-W1048555D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG10000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG10000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-W1048555H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG40000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG40000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-W1048555C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG5000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG5000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-W1048555E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG20000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG20000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-W1048555
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG1000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG1000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-D2906
-
|
|
Fluorescent Dye
|
Others
|
|
Alexa fluor 647 maleimide is a bright, far-red-emitting fluorescent dye for labeling of protein SH groups (Ex/Em = 656/670 nm). Alexa fluor 647 maleimide can be used to attach AF 647 fluorophore to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides). Alexa Fluor 647 maleimide is promising for research of cell biology, neuroscience, and disease diagnostics .
|
-
- HY-D2094
-
|
|
Fluorescent Dye
|
Inflammation/Immunology
Cancer
|
|
PerCP Maleimide is a fluorescent dye that reacts with free sulfhydryl groups on proteins. PerCP is a red fluorescence albuminous dye for immunostaining and Maleimide can be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes .
|
-
- HY-W011692
-
-
- HY-D2090
-
-
- HY-D1527
-
|
|
Fluorescent Dye
|
Others
|
|
N-(3-Fluoranthyl)maleimide is a thiol fluorescent probe with a lifetime of 20 nsec. N-(3-Fluoranthyl)maleimide has a maximum excitation wavelength of 370 nm and can be used to study the time-dependent processes of biopolymers .
|
-
- HY-W278706
-
|
|
Fluorescent Dye
|
Others
|
|
N-[4-(2-Benzimidazolyl)phenyl]maleimide is a potent fluorescent probe with excitation maximum of 315 nm and emission maximum of 360 nm. N-[4-(2-Benzimidazolyl)phenyl]maleimide can be used for fluorometry of thiol compounds .
|
-
![N-[4-(2-Benzimidazolyl)phenyl]maleimide](//file.medchemexpress.com/product_pic/hy-w278706.gif)
- HY-W591975
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Alkyne maleimide is a bifunctional linker reagent with a terminal malimide group and a propargyl group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The propargyl group can be linked to azide-containing biomolecules via Click Chemistry.
|
-
- HY-165929
-
-
- HY-116270
-
|
|
ADC Linker
|
Cancer
|
|
DBCO-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-136104
-
|
|
ADC Linker
|
Cancer
|
|
Methyltetrazine-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-Maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-W1048555A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG2000-SCM is a heterobifunctional PEG crosslinker bearing maleimide and succinimidyl carboxymethyl ester functional groups. MMal-PEG2000-SCM conjugates the F3 peptide to nanoparticles: the SCM group reacts with amino groups on the nanoparticle surface to form amide groups, while the MAL group reacts with thiol groups of the F3 peptide to form carbon-sulfur bonds. Mal-PEG-SCM enables unidirectional addition of linkers, ensuring that appropriate functional groups are available for RGD incorporation. Mal-PEG2000-SCM can be used in the development of nanoparticles targeting specific tumor cells .
|
-
- HY-W1048553H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG40000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG2000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG3400-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG20000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG1000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG5000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG10000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-166990
-
-
- HY-182132
-
-
- HY-175216
-
|
|
Drug-Linker Conjugates for ADC
Topoisomerase
|
Cancer
|
|
Maleimide-Ph(3,5-F)-PEG4-Val-Ala-MF-6 is a drug-linker conjugate for ADC. Maleimide-Ph(3,5-F)-PEG4-Val-Ala-MF-6 consists of a topoisomerase 1 inhibitor (Topi MF-6) (HY-175203) and a cleavable linker (Maleimide-Ph(3,5-F)-PEG4-Val-Ala) (HY-175218). Maleimide-Ph(3,5-F)-PEG4-Val-Ala-MF-6 can be used for synthesis of ADCs .
|
-
- HY-157920
-
|
N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PE-maleimide (N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine) is a bulky, membrane-impermeable, sulfhydryl-containing reagent with a relatively large molecular size. Biotin-PE-maleimide can be used for biotin labeling (such as thiol groups) and detection of proteins or other biomolecules .
|
-
- HY-W590586
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG4-NH-Boc is a PEG linker containing a maleimide group and a Boc protected amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The protected amine can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond.
|
-
- HY-W800803
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG5-NH-Boc is a PEG linker containing a maleimide group and a Boc protected amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The protected amine can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond.
|
-
- HY-133540
-
-
- HY-130908
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
11-Maleimidoundecanoic acid is a maleimide-containing hydrophobic core former. 11-Maleimidoundecanoic acid forms a hydrophobic core via maleimide-thiol coupling with cysteine residues on polypeptides, enabling stable loading and controllable release of Doxorubicin (HY-15142A). 11-Maleimidoundecanoic acid can be used for the research of breast cancer .
|
-
- HY-167036C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-PEG5000-Mal is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG5000-Mal can be used for drug delivery .
|
-
- HY-W1052492
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DPPE-PEG2000-Mal is a conjugate composed of DPPE, PEG chains, and maleimide (Mal). The maleimide group in DPPE-PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-W1052227A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMPE-PEG3400-Mal is a conjugate composed of DMPE, PEG chains, and maleimide (Mal). The maleimide group in DMPE-PEG3400-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-183126A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSG-PEG2000-Mal is a conjugate composed of DSG, PEG chains, and maleimide (Mal). The maleimide group in DSG-PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-167036A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-PEG1000-Mal is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG1000-Mal can be used for drug delivery .
|
-
- HY-183126B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSG-PEG3400-Mal is a conjugate composed of DSG, PEG chains, and maleimide (Mal). The maleimide group in DSG-PEG3400-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-183126D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSG-PEG10000-Mal is a conjugate composed of DSG, PEG chains, and maleimide (Mal). The maleimide group in DSG-PEG10000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-W1052227C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMPE-PEG1000-Mal is a conjugate composed of DMPE, PEG chains, and maleimide (Mal). The maleimide group in DMPE-PEG1000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-W1052227B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMPE-PEG5000-Mal is a conjugate composed of DMPE, PEG chains, and maleimide (Mal). The maleimide group in DMPE-PEG5000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-W1052492C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DPPE-PEG1000-Mal is a conjugate composed of DPPE, PEG chains, and maleimide (Mal). The maleimide group in DPPE-PEG1000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-W1052492B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DPPE-PEG5000-Mal is a conjugate composed of DPPE, PEG chains, and maleimide (Mal). The maleimide group in DPPE-PEG5000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-W1052227D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMPE-PEG10000-Mal is a conjugate composed of DMPE, PEG chains, and maleimide (Mal). The maleimide group in DMPE-PEG10000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-W1052492A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DPPE-PEG3400-Mal is a conjugate composed of DPPE, PEG chains, and maleimide (Mal). The maleimide group in DPPE-PEG3400-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-167036D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-PEG10000-Mal is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG10000-Mal can be used for drug delivery .
|
-
- HY-W1052492D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DPPE-PEG10000-Mal is a conjugate composed of DPPE, PEG chains, and maleimide (Mal). The maleimide group in DPPE-PEG10000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-183126C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSG-PEG5000-Mal is a conjugate composed of DSG, PEG chains, and maleimide (Mal). The maleimide group in DSG-PEG5000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-167036B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-PEG3400-Mal is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG3400-Mal can be used for drug delivery .
|
-
- HY-W1052227
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMPE-PEG2000-Mal is a conjugate composed of DMPE, PEG chains, and maleimide (Mal). The maleimide group in DMPE-PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-183126
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSG-PEG1000-Mal is a conjugate composed of DSG, PEG chains, and maleimide (Mal). The maleimide group in DSG-PEG1000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
-
- HY-D2309
-
|
|
Fluorescent Dye
Photosensitizer
|
Cancer
|
|
IRDye700Dx Maleimide is a Photosensitizer. When conjugated with HER2 Affibody and activated by near-infrared light, IRDye700Dx Maleimide induces death in HER2-positive breast cancer cells without causing damage to HER2-negative breast cancer cells .
|
-
- HY-165935
-
-
- HY-166990C
-
-
- HY-166990A
-
|
MeO-PEG10000-Mal
|
Biochemical Assay Reagents
|
|
|
Methoxypolyethylene glycol maleimide 10000 (MeO-PEG10000-Mal) is a biochemical reagent .
|
-
- HY-136562
-
|
|
MAGL
|
Metabolic Disease
|
|
N-Arachidonyl maleimide is a potent, irreversible inhibitor of monoacylglycerol lipase (MAGL) with an IC50 value of 140 nM .
|
-
- HY-W190924
-
|
|
ADC Linker
|
Cancer
|
|
Mal-amido-PEG8-Val-Gly is an ADC linker containing a maleimide group.
|
-
- HY-D1526
-
|
|
Fluorescent Dye
|
Others
|
|
N-(4-Anilino-1-naphthyl)maleimide is a fluorescent probe that can be used to detect thiol groups in proteins. N-(4-Anilino-1-naphthyl)maleimide reacts with thiol groups and immediately produces a stable fluorescent compound with the λex=355 nm, λem=448 nm .
|
-
- HY-167834
-
|
|
Fungal
Antibiotic
|
Infection
|
|
Farinomalein A is a maleimide that can be isolated from Paecilomyces farinosus. Farinomalein A has potent inhibition of Phytophtora sojae .
|
-
- HY-166990B
-
-
- HY-128925
-
AMAS
1 Publications Verification
|
ADC Linker
|
Cancer
|
|
AMAS is a nonclaevable heterobifunctional crosslinker with NHS ester and maleimide groups that allows covalent conjugation of amine- and sulfhydryl-containing molecules.
|
-
- HY-163790
-
|
|
PROTAC Linkers
|
Others
|
|
Desthiobiotin-PEG3-sulfo-Maleimide is a PEG linker can be used in the synthesis of PROTACs .
|
-
- HY-W800654
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG5-amine is a PEG linker containing a maleimide group and an amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
- HY-163789
-
|
|
ADC Linker
|
Cancer
|
|
Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
- HY-W190922
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG4-amine is a PEG linker containing a maleimide group and an amine group. The hydrophilic PEG spacer increases solubility in aqueous media. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
- HY-172505
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG12-t-butyl ester is a PEG linker containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
- HY-W068119A
-
|
2-Maleimidoethylamine hydrochloride
|
Biochemical Assay Reagents
|
Cancer
|
|
N-(2-Aminoethyl)maleimide (2-Maleimidoethylamine) hydrochloride is a selective covalent binding agent for thiol groups (RSGs), covalently binding to thiols via an irreversible thioether bond to prepare MMP-2-sensitive nanosystems. Under near-neutral conditions, the maleimide group in N-(2-Aminoethyl)maleimide hydrochloride binds to thiol groups via a nucleophilic addition reaction, and can be used to modify polymers or biological interfaces, enhancing mucosal adhesion and regulating the surface charge of biological interfaces. N-(2-Aminoethyl)maleimide hydrochloride can optimize the adhesion performance of drug delivery carriers and cell interactions with biological interfaces, and is applied in transmucosal drug delivery systems (such as drug carriers for oral and bladder sites) and biomaterial surface engineering research, providing support for tissue implantation, regeneration, and related drug delivery .
|
-
- HY-131023
-
|
JF549, Maleimide TFA
|
Fluorescent Dye
|
Others
|
|
Janelia Fluor® 549, Maleimide TFA (JF549, Maleimide TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-172721
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3B maleimide is a mono-reactive dye containing maleimide group, which can selectively and efficiently attach Cyanine3 fluorophore (an analog of Cy3) to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides). Cy3B is an improved version of Cy3 dyes with significantly increased fluorescence quantum yield and photostability.
|
-
- HY-W009037
-
|
|
PROTAC Linkers
|
Cancer
|
|
Maleimide-C10-NHS ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-159783
-
-
- HY-42359
-
|
|
PROTAC Linkers
|
Cancer
|
|
N-(4-Carboxycyclohexylmethyl)maleimide is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-152919
-
|
|
ADC Linker
|
Cancer
|
|
Mal-amide-PEG8-Val-Cit-PAB-OH is a cleavable ADC linker featuring a maleimide, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB functional group. Maleimide is used to covalently bind free thiols on the cysteine residues of proteins. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery with the help of the PAB structure.
|
-
- HY-D2381
-
|
|
Fluorescent Dye
|
Others
|
|
AF 488 maleimide is a thiol-reactive dye used to label SH groups of proteins, which can attach the AF 488 fluorophore to cysteine residue-containing proteins and peptides as well as other thiolated molecules. AF 488 maleimide enables real-time visualization of dynamic pilus extension and retraction in live bacterial cells via epifluorescence microscopy (Ex/Em = 470/520 nm) .
|
-
- HY-172291
-
|
|
ADC Linker
|
Cancer
|
|
Mal-amide-PEG8-Val-Cit-PAB-PNP is a cleavable ADC linker featuring a maleimide, a PEG spacer, a Val-Cit dipeptide, a PAB. and a PNP carbonate. Maleimide is a thiol-specific covalent linker which is used to label cysteine residues in proteins while the PNP group acts as a highly activated leaving group. Val-Cit linkers are cleaved by cytoplasmic peptidases.
|
-
- HY-130085
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG6-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 6-unit PEG and a NHS ester.
|
-
- HY-126506
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-PFP ester is a nonclaevable ADC linker containing a Maleimide group, 4-unit PEG and a PFP ester.
|
-
- HY-126504
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG2-NHS ester is a nonclaevable ADC linker containing a Maleimide group, 2-unit PEG and an NHS ester.
|
-
- HY-W800670
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-amido-PEG5-alkyne is a PEG linker containing a maleimide group and an alkyne. The hydrophilic PEG spacer increases solubility in aqueous media. The alkyne group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
- HY-W011433
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-(1-Pyrenyl)maleimide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-186175
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DMG-PEG2000-Mal-Cys-penetratin is a conjugate composed of dimyristoylglycerol (DMG), a PEG chain, and terminal maleimide (Mal). DMG-PEG2000-Mal-Cys-penetratin combines the membrane compatibility of lipids, the specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers) by maleimide, and cell-penetrating peptides, making it suitable for research on biomaterial construction and drug delivery to cells.
|
-
- HY-D1744
-
|
|
Fluorescent Dye
|
Others
|
|
ICG Maleimide is thiol reactive near infrared (NIR) fluorescent dye and used to generate a stable fluorescence signal in bioimaging (Ex/Em = 789/813 nm).
|
-
- HY-D1948
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 594 Maleimid is a maleimide ester derivative of ATTO 594, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 603/626 nm.
|
-
- HY-46398
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-Val-Phe-Boc is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Val-Phe-Boc can be used in the synthesis of the Deruxtecan .
|
-
- HY-130084
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG2-VCP-NB is a claevable ADC linker containing a Maleimide group, 2-unit PEG and a VCP NB.
|
-
- HY-D1936
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 465 Maleimid is a maleimide ester derivative of ATTO 465, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 453/506 nm.
|
-
- HY-D2020
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 665 maleimid is a maleimide ester derivative of ATTO 665, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 663/680 nm.
|
-
- HY-D2028
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 514 maleimid is a maleimide ester derivative of ATTO 514, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 511/531 nm.
|
-
- HY-D1986
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 620 Maleimid is a maleimide ester derivative of ATTO 620, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 620/642 nm.
|
-
- HY-D1960
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 633 Maleimid is a maleimide ester derivative of ATTO 633, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 630/651 nm.
|
-
- HY-D1976
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 610 Maleimid is a maleimide ester derivative of ATTO 610, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 616/633 nm.
|
-
- HY-D1982
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 725 Maleimid is a maleimide ester derivative of ATTO 725, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 728/751 nm.
|
-
- HY-D1994
-
|
|
Fluorescent Dye
|
Others
|
|
ATTO 647 Maleimid is a maleimide ester derivative of ATTO 647, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 630/651 nm.
|
-
- HY-N15951
-
|
|
Biochemical Assay Reagents
|
Others
|
|
C16 Ceramide-suc-PEG2K-maleimide is functionalized PEG lipid that can be used to synthesize lipid nanoparticles for drug delivery.
|
-
- HY-D0975
-
|
|
ADC Linker
|
Cancer
|
|
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.
|
-
- HY-W800719
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-Boc-N'-(PEG1-t-butyl ester)-L-Lysine-amido-Mal is the amino acid, lysine, with a maleimide at its C-terminus, a Boc-protecting group on its α-amine, and an amido-PEG1-t-butyl ester on its ε-amine. Maleimide is a thiol-reactive covalent group used to conjugate cysteine residues, while the Boc and the t-butyl ester can be later deprotected to perform further reactions.
|
-
- HY-155902E
-
|
Maleimide-PEG20000-Hydroxy
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG20000-OH (Maleimide-PEG20000-Hydroxy) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG20000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .
|
-
- HY-W144703
-
|
9-Aminoheptadecane
|
Biochemical Assay Reagents
|
Others
|
|
Heptadecan-9-amine (9-Aminoheptadecane) is PEG linker containing a maleimide and TFP ester end group. Maleimide groups are reactive with thiols between pH 6.5 and 7.5. The TFP ester can react with primary amine groups and is also less susceptible to undergo hydrolysis compared to NHS ester. The hydrophilic PEG chains increase the water solubility of a compound in aqueous media. Longer PEG chains have improved water solubility relative to shorter PEG chains.
|
-
- HY-155902H
-
|
Maleimide-PEG40000-Hydroxy
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG40000-OH (Maleimide-PEG40000-Hydroxy) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG40000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .
|
-
- HY-155902D
-
|
Maleimide-PEG10000-Hydroxy
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG10000-OH (Maleimide-PEG10000-Hydroxy) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG10000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .
|
-
- HY-155902C
-
|
Maleimide-PEG3400-Hydroxy
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG3400-OH (Maleimide-PEG3400-Hydroxy) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG3400-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .
|
-
- HY-160981
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-VCP-NB (Compound 17) is a degradable ADC linker containing a maleimide group, 4 PEG units and VCP NB .
|
-
- HY-174914
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Biotin-PEG4-mal is a PEG derivative composed of Biotin, 4 PEG units and Maleimide. Biotin can form a stable non-covalent bond with streptavidin.
|
-
- HY-W800648
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG2-Amide is a PEG linker with a maleimide group which can react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
- HY-D2239
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy3.5 maleimide is sulfonated modified Cy3.5 with good water solubility. λex=591 nm, λem=604 nm .
|
-
- HY-D2763
-
|
|
Fluorescent Dye
|
Others
|
|
BP Fluor 532 maleimide is a photostable, bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 dye can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.
Maleimide is the most popular sulfhydryl-reactive group for conjugating the dye to a thiol group on a protein, oligonucleotide thiophosphate, or low molecular weight ligand. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form a stable thioether bond. The resulting conjugates exhibit brighter fluorescence and greater photostability than the conjugates of many other spectrally similar fluorophores.
|
-
- HY-W800679
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-Cyclohexyl-PEG3-Biotin is a PEG linker containing a maleimide moiety and a biotin group. Maleimides react specifically with sulfhydryl groups to form a stable thioether linkage when the pH is between 6.5 and 7.5. The biotinylation can react with amine molecules in the presence of activator EDC or HATU. PEG attached to the biotin gives an extended spacer arm that permits the biotin to reach into the binding pocket of the protein. The PEG moiety also increases solubility of Biotin-PEG conjugates considerably.
|
-
- HY-W106411
-
|
Dithio-bis-maleimidoethane
|
Biochemical Assay Reagents
|
Others
|
|
DTME (dithio-bis-maleimidoethane) is a homobifunctional, maleimide crosslinker specifically designed for conjugation between sulfhydryl groups (-SH). DTME, whose molecular structure consists of two maleimide groups connected by an ethylene disulfide bridge, can specifically react with thiol - containing molecules (such as cysteine residues) to form stable covalent bonds. DTME allows crosslinks that can be cleaved with reducing agents such as DTT (HY-15917). DTME is commonly utilized to explore and characterize protein structure, particularly oligomerization, or protein interactions .
|
-
- HY-129655
-
|
|
ADC Linker
|
Cancer
|
|
Sulfo-SMPB sodium is a non-cleavable, heterobifunctional chemical cross-linking reagent which contains N-hydroxysuccinimide (NHS) ester and maleimide groups, allowing covalent conjugation of amine- and sulfhydryl-containing molecules .
|
-
- HY-160982
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG3-VCP-NB (Compund 25c) is a degradable ADC linker containing a maleimide group, 3-unit PEG and VCP NB .
|
-
- HY-126669
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-VA is a cleavable ADC linker containing a Maleimide group. Mal-PEG4-VA is used for making antibody-drug conjugate.
|
-
- HY-W1049129D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG40000-mal is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG40000-mal can be used for drug delivery .
|
-
- HY-W020780C
-
|
mPEG3400-Maleimide
|
Biochemical Assay Reagents
|
Others
|
|
mPEG3400-Mal is a PEG derivative used for thiol pegylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
-
- HY-W1049129C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG20000-mal is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG20000-mal can be used for drug delivery .
|
-
- HY-W020780A
-
|
mPEG350-Maleimide
|
Biochemical Assay Reagents
|
Others
|
|
mPEG350-Mal is a PEG derivative used for thiol PEGylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
-
- HY-W1049129B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG10000-mal is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG10000-mal can be used for drug delivery .
|
-
- HY-129526
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG3-NHS ester is a noncleavable ADC linker containing a Maleimide group. Mal-PEG3-NHS ester is used for making antibody-drug conjugate .
|
-
- HY-126668A
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-VC-PAB-DMEA TFA is a degradable ADC linker containing a maleimide group and can be used to synthesize antibody conjugate active molecules (ADCs) .
|
-
- HY-W020780B
-
|
mPEG750-Maleimide
|
Biochemical Assay Reagents
|
Others
|
|
mPEG750-Mal is a PEG derivative used for thiol pegylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
-
- HY-W190927
-
|
MC-Val-Cit-PAB-Doxorubicin
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
MC-Val-Cit-Doxorubicin (MC-Val-Cit-PAB-Doxorubicin) is drug-linker conjugate for ADC. The maleimide can conjugate with thiol containing molecules. Doxorubicin is an anthracycline antibiotic with antineoplastic activity
|
-
- HY-W1048552
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG1000-mal is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG1000-mal can be used for drug delivery .
|
-
- HY-137251
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Sulfo-MBS sodium is a heterobifunctional crosslinker with a maleimide group and an N-hydroxysuccinimide (NHS) ester group, which can react with cysteine residues and lysine residues on proteins. Sulfo-MBS sodium be used for protein cross-linking studies .
|
-
- HY-W017831
-
|
|
Biochemical Assay Reagents
Drug Intermediate
|
Others
|
|
2-Maleimido acetic acid is a maleimide-containing carboxylic acid ligand used to prepare Pt(IV) complexes capable of undergoing Diels-Alder reaction with furan derivatives for drug targeting and delivery applications .
|
-
- HY-171508
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Mal-PNU-159682 is a Drug-Linker Conjugates for ADC, composes of ADC linker (maleimide) and ADC cytotoxin PNU-159682 (HY-16700), and has anti-tumor activity .
|
-
- HY-156518
-
|
|
Biochemical Assay Reagents
|
Metabolic Disease
|
|
Glucose-malemide is a glycoconjugate consisting of a glucose molecule and a maleimide group of a linker molecule. Glucose-malemide can be used in the preparation of glucose-responsive insulin delivery compositions, thereby conjugating glucose to insulin .
|
-
- HY-W395122
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-PEG1-PNP-carbonate is a amine-reactive compound. PNP is a good leaving group. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
|
-
- HY-W440897
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG3400-SH is a maleimide reactive PEG lipid. The amphiphilic polymer forms lipid bilayer in water and can be used to prepare liposomes for drug nanocarriers to deliver mRNA, DNA or siRNA.
|
-
- HY-121030
-
|
N-(7-Dimethylamino-4-methyl-3-coumarinyl)maleimide
|
Fluorescent Dye
|
Others
|
|
DACM (N-(7-Dimethylamino-4-methyl-3-coumarinyl)maleimide) is a thiol-directed fluorescent dye (Ex=396 nm, Em=468 nm) .
|
-
- HY-175218
-
|
|
ADC Linker
|
Cancer
|
|
Maleimide-Ph(3,5-F)-PEG4-Val-Ala is a cleavable PEG-based ADC linker that can be used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W190796
-
|
|
PROTAC Linkers
|
Others
|
|
Mal-PEG3-NH2 is a linear heterobifunctional PEG reagent with a maleimide and an amine. Mal-PEG3-NH2 is a crosslinking reagent with a PEG spacer .
|
-
- HY-130818
-
|
|
ADC Linker
|
Cancer
|
|
N-(5-Hydroxypentyl)maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as Gemcitabine-O-Si(di-iso)-O-Mc (HY-130812) ) .
|
-
- HY-174279
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
MCC-AAQ-Exa is a drug-linker conjugates for ADC, obtained by condensing the linker with Exatecan (HY-13631) and can be used to prepare antibody-drug conjugates (ADCs). MCC is an ADC linker containing a maleimide fragment .
|
-
- HY-179205B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLA5000-PEG3400-MAL is a PEG derivative with a maleimide group at the end. PLA5000-PEG3400-MAL can be used for drug delivery .
|
-
- HY-179198C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLA2000-PEG5000-MAL is a PEG derivative with a maleimide group at the end. PLA2000-PEG5000-MAL can be used for drug delivery .
|
-
- HY-W440722
-
|
|
Liposome
|
Others
|
|
Cholesterol-PEG1000-Thiol is a PEGylated lipid that forms micelles in water and can be used to prepare liposomes or nanoparticles as drug delivery systems. The thiol moiety reacts with maleimide to form a stable thioether bond .
|
-
- HY-179198A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLA2000-PEG2000-MAL is a PEG derivative with a maleimide group at the end. PLA2000-PEG2000-MAL can be used for drug delivery .
|
-
- HY-185492
-
-
- HY-179205
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLA5000-PEG1000-MAL is a PEG derivative with a maleimide group at the end. PLA5000-PEG1000-MAL can be used for drug delivery .
|
-
- HY-179205C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLA5000-PEG5000-MAL is a PEG derivative with a maleimide group at the end. PLA5000-PEG5000-MAL can be used for drug delivery .
|
-
- HY-179198
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLA2000-PEG1000-MAL is a PEG derivative with a maleimide group at the end. PLA2000-PEG1000-MAL can be used for drug delivery .
|
-
- HY-W440719
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG2000-MAL is a PEG derivative and can be used to prepare liposome or nanoparticle due to its ability to self-assemble in water. The maleimide moiety is reactive with thiol molecule to form a covalent thioether bond.
|
-
- HY-179206B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLA10000-PEG3400-MAL is a PEG derivative with a maleimide group at the end. PLA10000-PEG3400-MAL can be used for drug delivery .
|
-
- HY-179206
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLA10000-PEG1000-MAL is a PEG derivative with a maleimide group at the end. PLA10000-PEG1000-MAL can be used for drug delivery .
|
-
- HY-179206A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLA10000-PEG2000-MAL is a PEG derivative with a maleimide group at the end. PLA10000-PEG2000-MAL can be used for drug delivery .
|
-
- HY-179205A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLA5000-PEG2000-MAL is a PEG derivative with a maleimide group at the end. PLA5000-PEG2000-MAL can be used for drug delivery .
|
-
- HY-W615173
-
|
|
Biochemical Assay Reagents
|
Others
|
|
NHS ester-C2-NHCO-C2-NHS is a heterobifunctional PEG linker, featuring a terminal NHS ester that can be used to label amine compounds and maleimide group for reactions with thiol groups.
|
-
- HY-W590555
-
|
|
Liposome
|
Cancer
|
|
Thiol-PEG2000-DMG is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc.
|
-
- HY-179206C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLA10000-PEG5000-MAL is a PEG derivative with a maleimide group at the end. PLA10000-PEG5000-MAL can be used for drug delivery .
|
-
- HY-179198B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
PLA2000-PEG3400-MAL is a PEG derivative with a maleimide group at the end. PLA2000-PEG3400-MAL can be used for drug delivery .
|
-
- HY-42360
-
SMCC
1 Publications Verification
|
ADC Linker
|
Cancer
|
|
SMCC is a protein crosslinker. SMCC contains an amine-reactive N-hydroxysuccinimide ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses .
|
-
- HY-126671
-
|
|
ADC Linker
|
Cancer
|
|
Mal-Phe-C4-Val-Cit-PAB is a cleavable ADC linker containing a Maleimide group. Mal-Phe-C4-Val-Cit-PAB is used for making antibody-drug conjugate.
|
-
- HY-W190796A
-
|
|
PROTAC Linkers
|
Others
|
|
Mal-PEG3-NH2 TFA is a linear heterobifunctional PEG reagent with a maleimide and an amine. Mal-PEG3-NH2 TFA is a crosslinking reagent with a PEG spacer .
|
-
- HY-126668
-
|
|
ADC Linker
|
Cancer
|
|
Mal-PEG4-VC-PAB-DMEA is a cleavable ADC linker containing a Maleimide group. Mal-PEG4-VC-PAB-DMEA is used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W440724
-
|
|
Liposome
|
Cancer
|
|
Cholesterol-PEG3400-Thiol is an amphiphatic PEG derivative which forms micelles in water and can be used to prepare liposomes or nanoparticles for drug delivery system. The thiol moiety is reactive with maleimide to form a stable thioether bond.
|
-
- HY-164340
-
|
|
Drug Metabolite
|
Cancer
|
|
Boc-NH-PAB(triacetyl-β-D-glucopyranuronate)-PNP (Compound 16) is a β-glucuronide-type linker precursor that couples with NeoDegrader P1 to synthesize the NeoDegrader P1-β-Glucuronide Linker Complex. Boc-NH-PAB(triacetyl-β-D-glucopyranuronate)-PNP and its derived linker-payload complexes can be used for the research of acute myeloid leukemia .
|
-
- HY-13631E
-
Deruxtecan
Maximum Cited Publications
25 Publications Verification
MC-GGFG-DXD
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing Trastuzumab deruxtecan (HY-138298A) and Patritumab deruxtecan (HY-P99813) .
|
-
- HY-126674
-
|
|
ADC Linker
|
Cancer
|
|
Mal-Phe-C4-Val-Cit-PAB-DMEA is a cleavable ADC linker containing a Maleimide group. Mal-Phe-C4-Val-Cit-PAB-DMEA is used for making antibody-drug conjugate.
|
-
- HY-W1048510B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-Arm PEG20000-Mal is a multi-arm PEG derivative with maleimide groups at each end of the 2 arms. 2-Arm PEG20000-Mal can be used for drug delivery .
|
-
- HY-W1048605C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG40000-Mal is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG40000-Mal can be used for drug delivery .
|
-
- HY-W1048510C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-Arm PEG40000-Mal is a multi-arm PEG derivative with maleimide groups at each end of the 2 arms. 2-Arm PEG40000-Mal can be used for drug delivery .
|
-
- HY-126673
-
|
|
ADC Linker
|
Cancer
|
|
Mal-C2-Gly3-EDA is a cleavable ADC linker containing a Maleimide group. Mal-C2-Gly3-EDA is used for making antibody-drug conjugate.
|
-
- HY-W441007
-
|
|
Liposome
|
Inflammation/Immunology
Cancer
|
|
DSPE-MAL is a phospholipid compound with a maleimide reactive group. DSPE-MAL contains two saturated fatty acids and can self-assemble in water to form a lipid bilayer. DSPE-MAL can be used to prepare liposomes as nanocarriers for active molecules .
|
-
- HY-W1048510D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-Arm PEG5000-Mal is a multi-arm PEG derivative with maleimide groups at each end of the two arms. 2-Arm PEG5000-Mal can be used for drug delivery .
|
-
- HY-W1048605B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG10000-Mal is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG10000-Mal can be used for drug delivery .
|
-
- HY-W1048605A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG20000-Mal is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG20000-Mal can be used for drug delivery .
|
-
- HY-W1048510A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
2-Arm PEG10000-Mal is a multi-arm PEG derivative with maleimide groups at each end of the 2 arms. 2-Arm PEG10000-Mal can be used for drug delivery .
|
-
- HY-108639
-
MIRA-1
2 Publications Verification
NSC 19630
|
MDM-2/p53
Apoptosis
|
Cancer
|
|
MIRA-1 is a maleimide analogue. MIRA-1 can induce apoptosis in mutant p53 cells via restoration of p53-dependent transcriptional transactivation. MIRA-1 has anticancer activity .
|
-
- HY-W1048605
-
|
|
Biochemical Assay Reagents
|
Others
|
|
8-Arm PEG5000-Mal is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG5000-Mal can be used for drug delivery .
|
-
- HY-D3242
-
|
FD-1080-MAL
|
Fluorescent Dye
|
Others
|
|
FD-1080 Maleimide (FD-1080-MAL) is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 can be used for in vivo imaging .
|
-
- HY-155901
-
|
Maleimide-NH-PEG2000-amine TFA
|
Biochemical Assay Reagents
|
Others
|
|
Mal-NH-PEG2000-NH2TFA is a PEG derivative that may be used for thiol PEGylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
-
- HY-W040289
-
|
|
ADC Linker
|
Cancer
|
|
Mal-amido-PEG2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
|
-
- HY-D2373
-
|
|
Fluorescent Dye
|
Others
|
|
CY5.5-PEG2000-Mal is used for preparing fluorescently labeled molecules. It is formed by condensing maleimide groups (Mal), PEG2000, and fluorescent dye CY5.5 (HY-D0924) .
|
-
- HY-D2374
-
|
|
Fluorescent Dye
|
Others
|
|
CY5.5-PEG5000-Mal is used for preparing fluorescently labeled molecules. It is formed by condensing maleimide groups (Mal), PEG5000, and fluorescent dye CY5.5 (HY-D0924) .
|
-
- HY-126672
-
|
|
ADC Linker
|
Cancer
|
|
Mal-amide-PEG4-Val-Cit-PAB-OH is a cleavable ADC linker containing a Maleimide group. Mal-amide-PEG4-Val-Cit-PAB-OH is used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-174809A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG600-Mal is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-D2800
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG400-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG400-MAL can be used for fluorescent labeling and imaging .
|
-
- HY-174809E
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG5000-Mal is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-D2800B
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG3400-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG3400-MAL can be used for fluorescent labeling and imaging .
|
-
- HY-174809H
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG10000-Mal is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-D2800C
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG5000-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG5000-MAL can be used for fluorescent labeling and imaging .
|
-
- HY-D2800A
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG1000-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG1000-MAL can be used for fluorescent labeling and imaging .
|
-
- HY-174809
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG400-Mal is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-174809C
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG2000-Mal is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-174809D
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG3400-Mal is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-D2800D
-
|
|
Fluorescent Dye
|
Others
|
|
FITC-PEG10000-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG10000-MAL can be used for fluorescent labeling and imaging .
|
-
- HY-174809B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
6-Arm-PEG1000-Mal is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-W001851
-
|
N-Benzylmaleimide
|
Drug Intermediate
|
Others
|
|
1-Benzylpyrrole-2,5-dione (N-Benzylmaleimide) is a heterocyclic compound containing a maleimide ring and a benzyl group. 1-Benzylpyrrole-2,5-dione can be used as a key reactant for the green chemical modification of cellulose nanocrystals (CNC).
|
-
- HY-D2497
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo Cy7 bis-SH is a fluorescent dye that contains sulfonated Cyanine7 (Sulfo-CY7) fluorescent dye and thiol (-SH) functional group. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
-
- HY-126509
-
|
|
ADC Linker
|
Cancer
|
|
Mal-amido-PEG10-C2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules .
|
-
- HY-126508
-
|
|
ADC Linker
|
Cancer
|
|
Mal-amido-PEG10-C2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules
|
-
- HY-13631ES4
-
-
- HY-W588728
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG8-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
-
- HY-W588736
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DBCO-PEG23-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
-
- HY-148459
-
|
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
ATAC21, a linker-immune-stimulatory compound that can be formed by conjugating a noncleavable maleimide-PEG4 linker containing a succinimide group with an immune- stimulatory compound. ATAC21 can be combined with SBT-040 (anti-CD40 antibody) to form a conjugate .
|
-
- HY-126507
-
|
|
ADC Linker
|
Cancer
|
|
Mal-amido-PEG1-C2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules
|
-
- HY-13631ES
-
-
- HY-13631ES3
-
|
MC-GGFG-DXD-d2
|
Drug-Linker Conjugates for ADC
Isotope-Labeled Compounds
|
Others
|
|
Deruxtecan-d2 is the deuterium labeled Deruxtecan (HY-13631E) . Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
|
-
- HY-W800805
-
|
|
Liposome
|
Cancer
|
|
DOPE-Mal is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions with a terminal maliemide group. The maleimide group will react with a thiol group to form a covalent bond. The hydrophilic PEG spacer increases solubility in aqueous media.
|
-
- HY-46346
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-Gly-NH-CH2-O-CH2-Cbz is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Gly-NH-CH2-O-CH2-Cbz can be used in the synthesis of the Deruxtecan .
|
-
- HY-13631ES2
-
|
MC-GGFG-DXD-d4-1
|
Drug-Linker Conjugates for ADC
Isotope-Labeled Compounds
|
Others
|
|
Deruxtecan-d4-1 is the deuterium labeled Adenosine Deruxtecan (HY-13631E) . Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
|
-
- HY-149117
-
|
|
Fluorescent Dye
|
Others
|
|
AF430 NHS ester is an AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF430 NHS ester can be uesd for the labeling of amino-groups in peptides, proteins, and oligonucleotides. To achieve specific coupling of dye labels and biomolecules .
|
-
- HY-164088
-
-
- HY-W1048849B
-
|
4-Arm PEG-thiol (MW 10000)
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm PEG-SH (MW 10000) (4-Arm PEG-thiol (MW 10000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
|
-
- HY-45669
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Cbz is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Cbz can be used in the synthesis of the Deruxtecan .
|
-
- HY-W020780
-
|
mPEG5000-Maleimide
|
Biochemical Assay Reagents
|
Cancer
|
|
mPEG5000-Mal (mPEG5000-Maleimide) is a PEG-derived selective covalent binding agent for sulfhydryl groups (RSGs), which can form irreversible thioether bonds with sulfhydryl groups under near-neutral conditions via the maleimide group. The mechanism of action of mPEG5000-Mal can be divided into two categories: firstly, as an enzyme modifier, it binds to target proteins through hydrophobic interactions, hydrogen bonds, and van der Waals forces, altering the protein's secondary structure; secondly, as a nanoparticle surface modifier, it covalently binds to sulfhydryl groups on the surface of red blood cells, changing the surface properties and morphology of the red blood cells, leading to their phagocytosis by macrophages of the reticuloendothelial system. mPEG5000-Mal can react with free cysteine in proteins, increasing the apparent molecular weight of the modified protein by 10-15 kDa for detection purposes. mPEG5000-Mal can enhance the thermal stability and catalytic activity of enzymes, and improve the macrophage targeting of nanoparticles, enabling targeted drug delivery. mPEG5000-Mal can be applied in enzyme engineering research in the food industry and in oncology, assisting radiotherapy by inhibiting tumor-associated macrophage infiltration and enhancing anti-tumor immune responses .
|
-
- HY-P1801
-
|
Cys-[HIV-Tat (47-57)]
|
HIV
Drug Derivative
|
Others
|
|
Cys-TAT(47-57) (Cys-[HIV-Tat (47-57)]), TAT (HY-P0281) derivative, is a Cysteine (HY-Y0337)-tagged cell-penetrating peptide (CPP) derived from the HIV TAT protein. Cys-TAT(47-57) can be used for the research for the research of drug delivery .
|
-
- HY-W1048849D
-
|
4-Arm PEG40000-thiol
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm PEG40000-SH (4-Arm PEG40000-thiol) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
|
-
- HY-49453
-
|
|
PROTAC Linkers
|
Cancer
|
|
Fmoc-Gly-Gly-(D-Phe)-Gly-CH2-O-CH2-Cbz is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Gly-Gly-(D-Phe)-Gly-CH2-O-CH2-Cbz can be used in the synthesis of the Deruxtecan .
|
-
- HY-D2530
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG3400-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2529
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG2000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-W1048849A
-
|
4-Arm PEG5000-thiol
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm PEG5000-SH (4-Arm PEG5000-thiol) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
|
-
- HY-W1048849C
-
|
4-Arm PEG20000-thiol
|
Biochemical Assay Reagents
|
Others
|
|
4-Arm PEG20000-SH (4-Arm PEG20000-thiol) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
|
-
- HY-D2531
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG5000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2532
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5-PEG10000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2509
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG1000-SH is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
-
- HY-D2883A
-
|
Rhodamine B-PEG600-SH
|
Fluorescent Dye
|
Others
|
|
RB-PEG600-SH (Rhodamine B-PEG600-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .
|
-
- HY-D2883E
-
|
Rhodamine B-PEG5000-SH
|
Fluorescent Dye
|
Others
|
|
RB-PEG5000-SH (Rhodamine B-PEG5000-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .
|
-
- HY-D2883B
-
|
Rhodamine B-PEG1000-SH
|
Fluorescent Dye
|
Others
|
|
RB-PEG1000-SH (Rhodamine B-PEG1000-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .
|
-
- HY-D2883C
-
|
Rhodamine B-PEG2000-SH
|
Fluorescent Dye
|
Others
|
|
RB-PEG2000-SH (Rhodamine B-PEG2000-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .
|
-
- HY-D2883H
-
|
Rhodamine B-PEG10000-SH
|
Fluorescent Dye
|
Others
|
|
RB-PEG10000-SH (Rhodamine B-PEG10000-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .
|
-
- HY-D2883D
-
|
Rhodamine B-PEG3400-SH
|
Fluorescent Dye
|
Others
|
|
RB-PEG3400-SH (Rhodamine B-PEG3400-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .
|
-
- HY-D2883
-
|
Rhodamine B-PEG400-SH
|
Fluorescent Dye
|
Others
|
|
RB-PEG400-SH (Rhodamine B-PEG400-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .
|
-
- HY-D2512
-
|
|
Fluorescent Dye
|
Others
|
|
Cy3-PEG5000-SH is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
-
- HY-D2589
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 PEG-SH is a fluorescent labeling reagent that combines CY7.5 (HY-D0926) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 770/820 nm).
|
-
- HY-D2556
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG1000-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2557
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG3400-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2885H
-
|
Rhodamine B-PEG10000-Mal
|
Fluorescent Dye
|
Others
|
|
RB-PEG10000-Mal (Rhodamine B-PEG10000-Mal) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG10000-Mal can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
-
- HY-D2885E
-
|
Rhodamine B-PEG5000-Mal
|
Fluorescent Dye
|
Others
|
|
RB-PEG5000-Mal (Rhodamine B-PEG5000-Mal) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG5000-Mal can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
-
- HY-D2559
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG10000-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2558
-
|
|
Fluorescent Dye
|
Others
|
|
Cy5.5-PEG5000-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2885
-
|
Rhodamine B-PEG400-Mal
|
Fluorescent Dye
|
Others
|
|
RB-PEG400-Mal (Rhodamine B-PEG400-Mal) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG400-Mal can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
-
- HY-D2885A
-
|
Rhodamine B-PEG600-Mal
|
Fluorescent Dye
|
Others
|
|
RB-PEG600-Mal (Rhodamine B-PEG600-Mal) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG600-Mal can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
-
- HY-D2885C
-
|
Rhodamine B-PEG2000-Mal
|
Fluorescent Dye
|
Others
|
|
RB-PEG2000-Mal (Rhodamine B-PEG2000-Mal) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG2000-Mal can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
-
- HY-D2885B
-
|
Rhodamine B-PEG1000-Mal
|
Fluorescent Dye
|
Others
|
|
RB-PEG1000-Mal (Rhodamine B-PEG1000-Mal) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG1000-Mal can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
-
- HY-D2885D
-
|
Rhodamine B-PEG3400-Mal
|
Fluorescent Dye
|
Others
|
|
RB-PEG3400-Mal (Rhodamine B-PEG3400-Mal) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG3400-Mal can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
-
- HY-108639R
-
|
NSC 19630 (Standard)
|
Reference Standards
MDM-2/p53
Apoptosis
|
Cancer
|
|
MIRA-1 (Standard) is the analytical standard of MIRA-1 (HY-108639). This product is intended for research and analytical applications. MIRA-1 is a maleimide analogue. MIRA-1 can induce apoptosis in mutant p53 cells via restoration of p53-dependent transcriptional transactivation. MIRA-1 has anticancer activity .
|
-
- HY-W800722
-
|
|
Biochemical Assay Reagents
|
Others
|
|
N-(PEG1-acid)-L-Lysine-amido-Mal is a PEG based linker with terminal malimide and carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
|
-
- HY-171337B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
C18-PEG5000-Mal is a conjugate composed of a octadecyl (C18 aliphatic chain), a PEG chain, and maleimide (Mal). C18-PEG5000-Mal combines the membrane compatibility of lipids with the specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), making it suitable for research in biomaterial construction and drug delivery.
|
-
- HY-183135
-
|
|
Biochemical Assay Reagents
|
Others
|
|
C16-PEG2000-Mal is a conjugate composed of a hexadecyl (C16 aliphatic chain), a PEG chain, and maleimide (Mal). C16-PEG2000-Mal combines the membrane compatibility of lipids with the specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), making it suitable for research in biomaterial construction and drug delivery.
|
-
- HY-W591479
-
|
|
ADC Linker
|
Cancer
|
|
MC-Val-Ala-NHS ester is a cleavable ADC linker with a malimide group and an NHS ester group. The Val-Ala linkers can be cleaved by Cathepsin B. Maleimide group is reactive toward thiol groups. MC is reactive with thiol moieties. The NHS ester is able to react specifically and efficiently with amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic condition to form a covalent bond.
|
-
- HY-147262
-
|
|
Antibody-Oligonucleotide Conjugates (AOCs)
Small Interfering RNA (siRNA)
|
Neurological Disease
|
|
Etedesiran is a component of the AOC drug Delpacibart etedesiran (HY-177565), formed by the reaction of an siRNA that induces cleavage of mRNA encoding myotonic dystrophy protein kinase (MTPK or DMPK) with SMCC linker (HY-42360). Etedesiran carries a maleimide group at its terminus, which can react with cysteine or lysine and is used for the synthesis of AOC drugs. Etedesiran is applicable to research related to myotonic dystrophy type 1 .
|
-
- HY-171337
-
|
|
Biochemical Assay Reagents
|
Others
|
|
C18-PEG2000-Mal is a conjugate composed of a octadecyl (C18 aliphatic chain), a PEG chain, and maleimide (Mal). C18-PEG2000-Mal combines the membrane compatibility of lipids with the specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), making it suitable for research in biomaterial construction and drug delivery.
|
-
- HY-183135A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
C16-PEG3400-Mal is a conjugate composed of a hexadecyl (C16 aliphatic chain), a PEG chain, and maleimide (Mal). C16-PEG3400-Mal combines the membrane compatibility of lipids with the specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), making it suitable for research in biomaterial construction and drug delivery.
|
-
- HY-183135B
-
|
|
Biochemical Assay Reagents
|
Others
|
|
C16-PEG5000-Mal is a conjugate composed of a hexadecyl (C16 aliphatic chain), a PEG chain, and maleimide (Mal). C16-PEG5000-Mal combines the membrane compatibility of lipids with the specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), making it suitable for research in biomaterial construction and drug delivery.
|
-
- HY-186176
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DSPE-PEG2000-Mal-Cys-penetratin is a conjugate composed of DSPE, a PEG chain, and terminal maleimide (Mal). DSPE-PEG2000-Mal-Cys-penetratin combines the membrane compatibility of lipids, the ability to undergo specific Michael addition reactions with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), and the ability to penetrate cell membranes, making it suitable for research on biomaterial construction and drug delivery to cells.
|
-
- HY-D1390A
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy5-Mal is a fluorescent dye derivative composed of a CY5 dye and a maleimide functional group. Sulfo-Cy5-Mal specifically covalently binds to thiol-containing (-SH) biomolecules. Sulfo-Cy5-Mal can be used for protein labeling, antibody conjugation, molecular imaging, and drug delivery studies (Ex/Em = 633 nm/670 nm) .
|
-
- HY-D1390
-
|
|
Fluorescent Dye
|
Others
|
|
Sulfo-Cy5-Mal potassium is a fluorescent dye derivative composed of a CY5 dye and a maleimide functional group. Sulfo-Cy5-Mal potassium specifically covalently binds to thiol-containing (-SH) biomolecules. Sulfo-Cy5-Mal potassium can be used for protein labeling, antibody conjugation, molecular imaging, and drug delivery studies (Ex/Em = 633 nm/670 nm) .
|
-
- HY-173639
-
|
|
Antibody-Drug Conjugates (ADCs)
Topoisomerase
Apoptosis
|
Cancer
|
|
AZD0516 is a first-in-class antibody-drug conjugate (ADC) targeting six-transmembrane epithelial antigen of the prostate-2 (STEAP2). The anti-STEAP2 monoclonal antibody (mAb) is conjugated via interchain cysteines to a maleimide-reactive, β-glucuronidase-cleavable linker (HY-173635) bearing the topoisomerase 1 inhibitor, Exatecan (HY-13631). AZD0516 can be used for the study of prostate cancer .
|
-
- HY-13631EG
-
|
MC-GGFG-DXD
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Deruxtecan (GMP) (MC-GGFG-DXD (GMP)) is Deruxtecan (HY-13631E) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing Trastuzumab deruxtecan (HY-138298A) and Patritumab deruxtecan (HY-P99813) .
|
-
- HY-143218
-
TPE-MI
Maximum Cited Publications
14 Publications Verification
Tetraphenylethene maleimide
|
Huntingtin
Parasite
|
Infection
Neurological Disease
|
|
TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasites Plasmodium falciparum .
|
-
- HY-W1048545H
-
|
Amine-PEG1000-Thiol hydrochloride
|
Biochemical Assay Reagents
|
Others
|
|
H2N-PEG1000-SH (Amine-PEG1000-Thiol) hydrochloride is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG1000-SH hydrochloride is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
-
- HY-W1048545I
-
|
Amine-PEG3400-Thiol hydrochloride
|
Biochemical Assay Reagents
|
Others
|
|
H2N-PEG3400-SH (Amine-PEG3400-Thiol) hydrochloride is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG3400-SH hydrochloride is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
-
- HY-W1048545E
-
|
Amine-PEG20000-Thiol hydrochloride
|
Biochemical Assay Reagents
|
Others
|
|
H2N-PEG20000-SH (Amine-PEG20000-Thiol) hydrochloride is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG20000-SH hydrochloride is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
-
- HY-W1048545D
-
|
Amine-PEG10000-Thiol hydrochloride
|
Biochemical Assay Reagents
|
Others
|
|
H2N-PEG10000-SH (Amine-PEG10000-Thiol) hydrochloride is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG10000-SH hydrochloride is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
-
- HY-118112
-
|
|
Biochemical Assay Reagents
|
Others
|
|
4-N-Maleimidobenzoicacid-NHS is a PEG linker that finds utility in bioconjugation endeavors and protein labeling ventures. Specifically designed for selective reaction with thiol groups, the maleimide group establishes covalent linkages, thereby facilitating the coupling of proteins, peptides, or diverse molecules to thiol-bearing biomolecules. The NHS ester is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic conditions to form a covalent bond.
|
-
- HY-W1048545A
-
|
Amine-PEG2000-Thiol hydrochloride
|
Biochemical Assay Reagents
|
Others
|
|
H2N-PEG2000-SH (Amine-PEG2000-Thiol) hydrochloride is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG2000-SH hydrochloride is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
-
- HY-173635
-
|
|
ADC Linker
|
Cancer
|
|
Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB is an interchain cysteines to a Maleimide-reactive, β-glucuronidase-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as AZD0516 (HY-173639) .
|
-
![Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB](//file.medchemexpress.com/product_pic/hy-173635.gif)
- HY-W1048545J
-
|
Amine-PEG40000-Thiol hydrochloride
|
Biochemical Assay Reagents
|
Others
|
|
H2N-PEG40000-SH (Amine-PEG40000-Thiol) hydrochloride is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG40000-SH hydrochloride is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
-
- HY-42360G
-
|
|
ADC Linker
|
Inflammation/Immunology
Cancer
|
|
SMCC (GMP) is the GMP level of SMCC (HY-42360). GMP guidelines are used to produce SMCC (HY-42360) (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. SMCC (GMP) is a protein crosslinker. SMCC (GMP) contains an amine-reactive N-hydroxysuccinimide ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses.
|
-
- HY-W1048545C
-
|
Amine-PEG5000-Thiol hydrochloride
|
Biochemical Assay Reagents
|
Others
|
|
H2N-PEG5000-SH (Amine-PEG5000-Thiol) hydrochloride is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG5000-SH hydrochloride is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
-
- HY-DY1024
-
|
|
Huntingtin
Parasite
|
Infection
Neurological Disease
|
TPE-MI (Tetraphenylethene maleimide) (solution) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum .
Solvent and concentration: DMSO: 10 mM
|
-
- HY-113914
-
|
Elraglusib
|
GSK-3
Apoptosis
Autophagy
|
Cancer
|
|
9-ING-41 (Elraglusib) is a maleimide-based ATP-competitive and selective glycogen synthase kinase-3β (GSK-3β) inhibitor with an IC50 of 0.71 μM. 9-ING-41 significantly leads to cell cycle arrest, autophagy and apoptosis in cancer cells. 9-ING-41 has anticancer activity and has the potential for enhancing the antitumor effects of chemotherapeutic agents .
|
-
- HY-181777
-
|
|
EGFR
|
Cancer
|
|
Mal-Pip-ValCit-PAB-AZ7550 is a prodrug of EGFR inhibitor. Mal-Pip-ValCit-PAB-AZ7550 selectively binds covalently to albumin via its maleimide moiety. Mal-Pip-ValCit-PAB-AZ7550 exhibits potent in vivo anticancer activity in non-small cell lung cancer xenograft models. Mal-Pip-ValCit-PAB-AZ7550 can be used in research related to non-small cell lung cancer .
|
-
- HY-186171
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Mal-(1R,2S,3R,4S)-himic acid-alkyne is a trifunctional click chemistry scaffold containing complementary functionalities for copper catalyzed azide-alkyne (CuAAC), thiol-Michael addition, and inverse electron demand Diels-Alder (iEDDA) click reactions .
|
-
- HY-183022
-
|
|
Biochemical Assay Reagents
|
Others
|
|
1-(3-Azidopropyl)-1H-pyrrole-2,5-dione is a maleimide derivative with a 3-azidopropyl substituent, used to introduce an azide functional group to bovine serum albumin (BSA). 1-(3-Azidopropyl)-1H-pyrrole-2,5-dione reacts with the free, solvent-accessible thiol group of BSA to produce azide-functionalized BSA, which is used in click chemistry to form a TLL-BSA hetero-dimer .
|
-
- HY-132989
-
|
|
Biochemical Assay Reagents
Bacterial
|
Cardiovascular Disease
Infection
Inflammation/Immunology
|
|
Mal-Deferoxamine is a maleimide-functionalized trihydroxamate siderophore derivative that can be isolated from Streptomyces pilosus. Mal-Deferoxamine possesses highly specific Fe (III) chelating ability, and the stability of complexes formed between it and non-Fe (III) metal ions is significantly lower. Mal-Deferoxamine exhibits growth inhibitory effects against Gram-positive bacteria, but shows no obvious inhibitory activity against Gram-negative bacteria (MIC>50 μM). Mal-Deferoxamine is mainly suitable for scientific research in hematology and related fields .
|
-
- HY-N16328
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 maleimide chloride is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-D1565
-
|
|
Fluorescent Dye
|
Others
|
|
Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-N15791
-
|
|
Fluorescent Dye
|
Others
|
|
Cyanine3.5 maleimide chloride is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-D1323
-
|
Cy5.5 maleimide chloride
|
Fluorescent Dye
|
Others
|
|
Cyanine5.5 maleimide chloride is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-183675
-
|
|
Insecticide
|
Infection
|
|
SfUAP-IN-1 is an inhibitor of SfUAP (UDP-N-acetylglucosamine pyrophosphorylase from Spodoptera frugiperda) with an IC50 value of 108 nM. As a growth and development inhibitor, SfUAP-IN-1 impairs larval growth and development of Plutella xylostella (diamondback moth), Spodoptera frugiperda (fall armyworm) and Spodoptera litura (tobacco cutworm). SfUAP-IN-1 can be used in research on green pesticides targeting insect UAP .
|
-
- HY-DY1067
-
|
|
Fluorescent Dye
DNA Stain
|
Others
|
Cy5 maleimide (solution) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
Solvent and concentration: DMSO: 10 mM
|
-
- HY-171946
-
|
|
Drug-Linker Conjugates for ADC
Topoisomerase
|
Cancer
|
|
TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT is a drug-linker conjugate for ADC. TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT consists of a topoisomerase 1 inhibitor (Topi MF-6) (HY-175203) and a cleavable linker (Maleimide-Ph(3,5-F)-PEG4-Val-Ala) (HY-175218). TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT can be used for synthesis of ADCs .
|
-
![TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT](//file.medchemexpress.com/product_pic/hy-171946.gif)
- HY-183866
-
|
Maleimide-KGDEVD-doxorubicin
|
Peptide-Drug Conjugates (PDCs)
HSP
IFNAR
|
Cancer
|
|
MPD-1 (Maleimide-KGDEVD-doxorubicin) is a peptide drug conjugate (PDC). MPD-1 releases Doxorubicin (HY-15142) via radiation-activated caspase-3 cleavage, triggering a cytotoxic amplification cascade at the tumor site. MPD-1 enhances CD8 + T cell tumor infiltration, and activates antigen-presenting cells. MPD-1 enables dual-trigger payload release, amplifies cytotoxicity via in situ feedback, and selectively delivers payload to tumor microenvironments via enhanced albumin metabolism and macropinocytosis. MPD-1 exhibits antitumor efficacy in mouse colorectal cancer models. MPD-1 can be used for the research of colorectal cancer .
|
-
- HY-153360
-
|
|
Drug-Linker Conjugates for ADC
Topoisomerase
|
Cancer
|
|
MC-GGFG-AM-(10Me-11F-Camptothecin) is a linker-payload conjugate used to synthesize ZW251. ZW251 an antibody-drug conjugate (ADC) targeting human GPC3. ZW251 consists of a humanized IgG1 antibody conjugated to a novel camptothecin-based topoisomerase 1 inhibitor, ZD06519, via a linker. The linker is the maleimide anchor and a glycyl glycyl phenylalanyl glycine (GGFG)-aminomethyl (AM) cleavable linker. ZW251 has high affinity with human and cynomolgus monkey GPC3. ZW251 displays rapid internalization in GPC3-expressing HCC cell lines, and bystander-mediated killing of GPC3 negative cancer cells .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-138200
-
|
Cyanine5 maleimide
|
Fluorescent Dyes
|
|
Cy5 maleimide (Cyanine5 maleimide) is a single-reactive dye containing a maleimide group and a CY5 fluorescent group, which can selectively couple with a thiol group. Cy5 maleimide can be used to label antibodies, peptides, or proteins (Ex/Em = 646/664 nm).
|
-
- HY-D0098
-
|
N-(5-Fluoresceinyl)maleimide
|
Fluorescent Dyes
|
Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .
|
-
- HY-D0069
-
|
|
Fluorescent Dyes
|
|
CPM is a maleimide derivative, acting as a blue fluorescent thiol-reactive dye (excitation/emission maxima of 387/463 nm) .
|
-
- HY-D2906
-
|
|
Fluorescent Dyes
|
|
Alexa fluor 647 maleimide is a bright, far-red-emitting fluorescent dye for labeling of protein SH groups (Ex/Em = 656/670 nm). Alexa fluor 647 maleimide can be used to attach AF 647 fluorophore to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides). Alexa Fluor 647 maleimide is promising for research of cell biology, neuroscience, and disease diagnostics .
|
-
- HY-D1744
-
|
|
Fluorescent Dyes
|
|
ICG Maleimide is thiol reactive near infrared (NIR) fluorescent dye and used to generate a stable fluorescence signal in bioimaging (Ex/Em = 789/813 nm).
|
-
- HY-W998680
-
|
5-FITC-Maleimide
|
Fluorescent Dyes
|
|
Fluorescein-maleimide (5-FITC-Maleimide) is a thiol-reactive fluorescent derivatization reagent and non-specific protein labeling reagent. Fluorescein-maleimide covalently binds to protein thiol groups for protein labeling. Fluorescein-maleimide covalently binds to protein amino and imidazole groups under neutral pH conditions. Fluorescein-maleimide is used for fluorescent labeling of proteins, nucleic acids or other molecules containing one or more thiol groups (Ex/Em = 494/519 nm) .
|
-
- HY-D2381
-
|
|
Fluorescent Dyes
|
|
AF 488 maleimide is a thiol-reactive dye used to label SH groups of proteins, which can attach the AF 488 fluorophore to cysteine residue-containing proteins and peptides as well as other thiolated molecules. AF 488 maleimide enables real-time visualization of dynamic pilus extension and retraction in live bacterial cells via epifluorescence microscopy (Ex/Em = 470/520 nm) .
|
-
- HY-131029
-
|
JF646, Maleimide
|
Fluorescent Dyes
|
|
Janelia Fluor® 646, Maleimide (JF646, Maleimide) is a red fluorescent dye that contains a maleimide group. JF646, Maleimide can be used in cellular imaging . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-D1871
-
|
|
Fluorescent Dyes
|
|
Cy3 maleimide chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing maleimide functional groups. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The alkyne functional group of Cy3 maleimide chloride can undergo a "thiol-acrylamide" reaction with molecules containing sulfur-oxygen functional groups to form covalent bonds. Cy3 maleimide chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.
|
-
- HY-D2309
-
|
|
Fluorescent Dyes
|
|
IRDye700Dx Maleimide is a Photosensitizer. When conjugated with HER2 Affibody and activated by near-infrared light, IRDye700Dx Maleimide induces death in HER2-positive breast cancer cells without causing damage to HER2-negative breast cancer cells .
|
-
- HY-121030
-
|
N-(7-Dimethylamino-4-methyl-3-coumarinyl)maleimide
|
Fluorescent Dyes
|
|
DACM (N-(7-Dimethylamino-4-methyl-3-coumarinyl)maleimide) is a thiol-directed fluorescent dye (Ex=396 nm, Em=468 nm) .
|
-
- HY-W011618
-
|
|
Fluorescent Dyes
|
|
N-(9-Acridinyl)maleimide is a maleimide type fluorescent thiol reagent. N-(9-Acridinyl)maleimide shows no substantial fluorescence but its coupling products with thiol compounds exhibit strong blue fluorescence. N-(9-Acridinyl)maleimide is used for fluorometrical analysis of cysteine and glutathione .
|
-
- HY-137098
-
|
|
Fluorescent Dyes
|
|
Sulfo-Cy3 maleimide potassium is a fluorescent dye with a maleimide functionality at the end a short alkyl linker. Sulfo-Cy3 maleimide potassium can be used for the labeling of antibodies and other labile proteins .
|
-
- HY-W190932
-
|
|
Fluorescent Dyes
|
|
TAMRA-PEG2-Maleimide is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG2-Maleimide contains a maleimide group that can react with a thiol group to form a covalent bond.
|
-
- HY-D1566
-
|
|
Fluorescent Dyes
|
|
Sulfo-Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
- HY-D2498
-
|
|
Fluorescent Dyes
|
|
Cy7 maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides .
|
-
- HY-D2187
-
|
|
Fluorescent Dyes
|
|
6-TAMRA maleimide is a fluorescent dye composed of the fluorescent group of an avidin derivative and a maleimide group.
|
-
- HY-D2002
-
|
|
Fluorescent Dyes
|
|
ATTO 488 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 488 maleimide is a maleimide derivative of ATTO 488, which can be used to label proteins or antibodies.
|
-
- HY-D2529
-
|
|
Fluorescent Dyes
|
|
Cy5-PEG2000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2488
-
|
|
Fluorescent Dyes
|
|
Sulfo Cy5.5-maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides.
|
-
- HY-D1546
-
|
|
Fluorescent Dyes
|
|
Biotin-C2-maleimide is an antibody conjugate reagent, can bind to many biomolecules without significantly changing the biological activity of the target molecule .
|
-
- HY-D1869
-
|
|
Fluorescent Dyes
|
|
800CW maleimide is an infrared dye that can be used for labeling molecules that contain free sulfhydryl (–SH) groups (Ex: 778 nm; Em: 796 nm). 800CW maleimide binds to plasma proteins .
|
-
- HY-172721
-
|
|
Fluorescent Dyes
|
|
Cy3B maleimide is a mono-reactive dye containing maleimide group, which can selectively and efficiently attach Cyanine3 fluorophore (an analog of Cy3) to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides). Cy3B is an improved version of Cy3 dyes with significantly increased fluorescence quantum yield and photostability.
|
-
- HY-D2373
-
|
|
Fluorescent Dyes
|
|
CY5.5-PEG2000-Mal is used for preparing fluorescently labeled molecules. It is formed by condensing maleimide groups (Mal), PEG2000, and fluorescent dye CY5.5 (HY-D0924) .
|
-
- HY-D2497
-
|
|
Fluorescent Dyes
|
|
Sulfo Cy7 bis-SH is a fluorescent dye that contains sulfonated Cyanine7 (Sulfo-CY7) fluorescent dye and thiol (-SH) functional group. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
-
- HY-D2531
-
|
|
Fluorescent Dyes
|
|
Cy5-PEG5000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2556
-
|
|
Fluorescent Dyes
|
|
Cy5.5-PEG1000-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2182
-
|
|
Fluorescent Dyes
|
|
Preactivated PE-Cy5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.
|
-
- HY-D2180
-
|
|
Fluorescent Dyes
|
|
Preactivated APC-Cy5.5 Maleimide is a sulfhydryl reactive dye that reacts with free sulfhydryl groups on proteins. Preactivated APC-Cy5.5 Maleimide binds easily to proteins or antibodies, and does not change the spectral characteristics of APC-Cy/YF after activation.
|
-
- HY-D1592
-
|
|
Fluorescent Dyes
|
|
BODIPY TMR C5-maleimide is a fluorescent dye. BODIPY TMR C5-maleimide is a high quantum yield fluorophore which can be coupled with peptides .
|
-
- HY-D0152
-
|
|
Fluorescent Dyes
|
|
Tetramethylrhodamine-6-maleimide is a fluorescent dye with a reactive sulfhydryl-specific moiety is covalently coupled to this cysteine. Tetramethylrhodamine-6-maleimide can be used as labels to detect local protein motions of the fully active Na+/K+-ATPase in real time .
|
-
- HY-D1340
-
|
|
Fluorescent Dyes
|
|
Sulfo-Cyanine7 maleimide potassium is an analogue of Cy7 maleimide and a hydrophilic near-infrared fluorescent dye.
|
-
- HY-133540G
-
|
Maleimido-mono-amide-DOTA
|
Fluorescent Dyes
|
|
Maleimide-DOTA (Maleimido-mono-amide-DOTA) (GMP) is Maleimide-DOTA (HY-133540) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-D2021
-
|
|
Fluorescent Dyes
|
|
ATTO 550 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 maleimide is a maleimide derivative of ATTO 550, which can be used to label proteins or antibodies.
|
-
- HY-D1351
-
|
Sulfo-Cy5.5 maleimide potassium
|
Fluorescent Dyes
|
|
Sulfo-Cyanine5.5 maleimide (Sulfo-Cy5.5 maleimide) potassium is a fluorescent dye. Sulfo-Cyanine5.5 is a nearinfrared (NIR) fluorophore with excitation maximum 675 nm and emission maximum 694 nm. Sulfo-Cyanine5.5 maleimide potassium can be used for the labeling of sensitive proteins, nanoparticles, and highly hydrophylic biopolymers .
|
-
- HY-131023
-
|
JF549, Maleimide TFA
|
Fluorescent Dyes
|
|
Janelia Fluor® 549, Maleimide TFA (JF549, Maleimide TFA) is a fluorescent dye with the absorption maximum (λab (max)) of 549 nm and emission maximum (λem (max)) of 571 nm . Janelia Fluor® products are licensed under U.S. Pat. Nos. 9,933,417, 10,018,624 and 10,161,932 and other patents from Howard Hughes Medical Institute.
|
-
- HY-D1948
-
|
|
Fluorescent Dyes
|
|
ATTO 594 Maleimid is a maleimide ester derivative of ATTO 594, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 603/626 nm.
|
-
- HY-D2800
-
|
|
Fluorescent Dyes
|
|
FITC-PEG400-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG400-MAL can be used for fluorescent labeling and imaging .
|
-
- HY-D2800B
-
|
|
Fluorescent Dyes
|
|
FITC-PEG3400-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG3400-MAL can be used for fluorescent labeling and imaging .
|
-
- HY-D2800A
-
|
|
Fluorescent Dyes
|
|
FITC-PEG1000-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG1000-MAL can be used for fluorescent labeling and imaging .
|
-
- HY-D2532
-
|
|
Fluorescent Dyes
|
|
Cy5-PEG10000-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
-
- HY-D2589
-
|
|
Fluorescent Dyes
|
|
Cy7.5 PEG-SH is a fluorescent labeling reagent that combines CY7.5 (HY-D0926) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em = 770/820 nm).
|
-
- HY-D2103
-
|
|
Fluorescent Dyes
|
|
TAMRA-PEG3-Maleimide is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-Maleimide contains maleimide groups that react with thiol groups to form covalent bonds.
|
-
- HY-D2104
-
|
|
Fluorescent Dyes
|
|
TAMRA-PEG7-Maleimide is a dye derivative of TAMRA (HY-135640) containing 7 PEG units. TAMRA-PEG7-Maleimide contains a maleimide group that can react with a thiol group to form a covalent bond.
|
-
- HY-D0151
-
|
|
Fluorescent Dyes
|
|
Tetramethylrhodamine-5-maleimide is a fluorescent probe with high specificity for cysteine thiol (SH) groups. Tetramethylrhodamine-5-maleimide has high sensitivity, responds rapidly to negatively charged nanoparticles, and shows a concentration-dependent decrease in fluorescence intensity, but it is susceptible to interference from humic acids .
|
-
- HY-D0103
-
|
|
Fluorescent Dyes
|
|
Fluorescein diacetate 5-maleimide is a colorimetric probe formed by the reaction of adipic acid dihydrazide and fluorescein isothiocyanate.
|
-
- HY-171561G
-
|
|
Fluorescent Dyes
|
|
DOTAM-Maleimide triTFA (GMP) is DOTAM-Maleimide triTFA (HY-171561) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOTAM-Maleimide triTFA is a bifunctional chelator .
|
-
- HY-D2091
-
|
|
Fluorescent Dyes
|
|
PE-VF647 Maleimide is a double-dye dye that can undergo thiol reaction. It contains maleimide groups that can react with thiol groups to form covalent bonds. PE-VF647 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 665 nm.
|
-
- HY-D2093
-
|
|
Fluorescent Dyes
|
|
PE-VF750 Maleimide is a thiol-reactive double-dye dye that contains maleimide groups that can react with thiol groups to form covalent bonds. Ex/Em=495-566/777 nm. PE-VF750 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 777 nm.
|
-
- HY-D1925
-
|
|
Fluorescent Dyes
|
|
ATTO 425 Maleimide is a maleimide ester derivative of ATTO 425, which can be used to label proteins or antibodies. The maximum excitation emission wavelength: 439/489 nm.
|
- HY-D1918
-
|
|
Fluorescent Dyes
|
|
ATTO 390 maleimide is a maleimide ester derivative of ATTO 390, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 390/476 nm.
|
- HY-D2092
-
|
|
Fluorescent Dyes
|
|
PE-VF680 Maleimide is a double-dye dye that can undergo thiol reaction. It contains maleimide groups that can react with thiol groups to form covalent bonds. Ex/Em=495-566/701 nm. PE-VF680 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 701 nm.
|
- HY-D2150
-
|
|
Fluorescent Dyes
|
|
AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 maleimide contains maleimide groups that react with thiol groups to form covalent bonds. To achieve specific coupling of dye labels and biomolecules .
|
- HY-D2047
-
|
|
Fluorescent Dyes
|
|
ATTO 532 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 532 maleimide is a maleimide derivative of ATTO 532, which can be used to label proteins or antibodies.
|
- HY-D2063
-
|
|
Fluorescent Dyes
|
|
ATTO 740 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 740 maleimide is a maleimide derivative of ATTO 740, which can be used to label proteins or antibodies.
|
- HY-D1933
-
|
|
Fluorescent Dyes
|
|
ATTO 590 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 590 maleimide is a maleimide derivative of ATTO 590, which can be used to label proteins or antibodies.
|
- HY-D2059
-
|
|
Fluorescent Dyes
|
|
ATTO 700 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 700 maleimide is a maleimide derivative of ATTO 700, which can be used to label proteins or antibodies.
|
- HY-D2074
-
|
|
Fluorescent Dyes
|
|
ATTO 680 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 680 maleimide is a maleimide derivative of ATTO 680, which can be used to label proteins or antibodies.
|
- HY-D1961
-
|
|
Fluorescent Dyes
|
|
ATTO 565 maleimide is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 565 maleimide is a maleimide derivative of ATTO 565, which can be used to label proteins or antibodies.
|
- HY-D1618
-
|
|
Fluorescent Dyes
|
|
Cyanine3 maleimide tetrafluoroborate is a specific labeling reagent for sulfhydryl groups with the λex of 550 nm and λem of 580 nm. Cyanine3 maleimide tetrafluoroborate can be used for protein and peptide labeling .
|
- HY-D2231
-
|
|
Fluorescent Dyes
|
|
Cy3.5 maleimide is a relatively water-soluble fluorescent dye. Cy3.5 maleimide is soluble in organic solvents, including DMF, DMSO and acetonitrile and so on .
|
- HY-D2249
-
- HY-D2181
-
|
|
Fluorescent Dyes
|
|
Preactivated PE-Cy5.5 Maleimide is a Preactivated PE-Cy5.5 Maleimide, which is a dye that can be used to label molecules such as dye that can be used to label molecules such as antibodies .
|
- HY-D2094
-
|
|
Fluorescent Dyes
|
|
PerCP Maleimide is a fluorescent dye that reacts with free sulfhydryl groups on proteins. PerCP is a red fluorescence albuminous dye for immunostaining and Maleimide can be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes .
|
- HY-D2090
-
- HY-D1527
-
|
|
Fluorescent Dyes
|
|
N-(3-Fluoranthyl)maleimide is a thiol fluorescent probe with a lifetime of 20 nsec. N-(3-Fluoranthyl)maleimide has a maximum excitation wavelength of 370 nm and can be used to study the time-dependent processes of biopolymers .
|
- HY-D1526
-
|
|
Fluorescent Dyes
|
|
N-(4-Anilino-1-naphthyl)maleimide is a fluorescent probe that can be used to detect thiol groups in proteins. N-(4-Anilino-1-naphthyl)maleimide reacts with thiol groups and immediately produces a stable fluorescent compound with the λex=355 nm, λem=448 nm .
|
- HY-D1936
-
|
|
Fluorescent Dyes
|
|
ATTO 465 Maleimid is a maleimide ester derivative of ATTO 465, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 453/506 nm.
|
- HY-D2020
-
|
|
Fluorescent Dyes
|
|
ATTO 665 maleimid is a maleimide ester derivative of ATTO 665, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 663/680 nm.
|
- HY-D2028
-
|
|
Fluorescent Dyes
|
|
ATTO 514 maleimid is a maleimide ester derivative of ATTO 514, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 511/531 nm.
|
- HY-D1986
-
|
|
Fluorescent Dyes
|
|
ATTO 620 Maleimid is a maleimide ester derivative of ATTO 620, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 620/642 nm.
|
- HY-D1960
-
|
|
Fluorescent Dyes
|
|
ATTO 633 Maleimid is a maleimide ester derivative of ATTO 633, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 630/651 nm.
|
- HY-D1976
-
|
|
Fluorescent Dyes
|
|
ATTO 610 Maleimid is a maleimide ester derivative of ATTO 610, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 616/633 nm.
|
- HY-D1982
-
|
|
Fluorescent Dyes
|
|
ATTO 725 Maleimid is a maleimide ester derivative of ATTO 725, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 728/751 nm.
|
- HY-D1994
-
|
|
Fluorescent Dyes
|
|
ATTO 647 Maleimid is a maleimide ester derivative of ATTO 647, which can be used to label proteins or antibodies, with maximum excitation/emission wavelengths: 630/651 nm.
|
- HY-D2239
-
|
|
Fluorescent Dyes
|
|
Sulfo-Cy3.5 maleimide is sulfonated modified Cy3.5 with good water solubility. λex=591 nm, λem=604 nm .
|
- HY-D2374
-
|
|
Fluorescent Dyes
|
|
CY5.5-PEG5000-Mal is used for preparing fluorescently labeled molecules. It is formed by condensing maleimide groups (Mal), PEG5000, and fluorescent dye CY5.5 (HY-D0924) .
|
- HY-D2800C
-
|
|
Fluorescent Dyes
|
|
FITC-PEG5000-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG5000-MAL can be used for fluorescent labeling and imaging .
|
- HY-D2800D
-
|
|
Fluorescent Dyes
|
|
FITC-PEG10000-MAL is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and Maleimide (HY-W007324) (MAL). FITC-PEG10000-MAL can be used for fluorescent labeling and imaging .
|
- HY-149117
-
|
|
Fluorescent Dyes
|
|
AF430 NHS ester is an AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF430 NHS ester can be uesd for the labeling of amino-groups in peptides, proteins, and oligonucleotides. To achieve specific coupling of dye labels and biomolecules .
|
- HY-D2509
-
|
|
Fluorescent Dyes
|
|
Cy3-PEG1000-SH is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
- HY-D2883E
-
|
Rhodamine B-PEG5000-SH
|
Fluorescent Dyes
|
|
RB-PEG5000-SH (Rhodamine B-PEG5000-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .
|
- HY-D2883D
-
|
Rhodamine B-PEG3400-SH
|
Fluorescent Dyes
|
|
RB-PEG3400-SH (Rhodamine B-PEG3400-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .
|
- HY-D2883
-
|
Rhodamine B-PEG400-SH
|
Fluorescent Dyes
|
|
RB-PEG400-SH (Rhodamine B-PEG400-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .
|
- HY-DY1088
-
|
N-(5-Fluoresceinyl)maleimide (solution)
|
Fluorescent Dyes
|
Fluorescein-5-maleimide (solution) (N-(5-Fluoresceinyl)maleimide (solution)) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .
Solvent and concentration: DMSO: 10 mM
|
- HY-D3270
-
|
|
Fluorescent Dyes
|
|
IR 750 Maleimide is a near-infrared fluorescent dye composed of IRDye 750 near-infrared fluorophore and maleimide reactive group. IR 750 Maleimide can be applied to fluorescent labeling, imaging and detection.
|
- HY-D2932
-
|
SNAP-Maleimide
|
Fluorescent Dyes
|
|
BG-maleimide is a building block. BG-maleimide allows the attachment of Benzylguanine to thiolcontaining precursors .
|
- HY-D3252
-
|
|
Fluorescent Dyes
|
|
IR 650 maleimide is a near-infrared fluorescent dye. It should be noted that IR 650 maleimide‘s fluorescence stability is poor, with less than 16% of the fluorescence signal retained after the expansion microscopy experimental procedure .
|
- HY-D3052
-
|
|
Fluorescent Dyes
|
|
5(6)-carbonylated rhodamine 110 maleimide is a maleimide-based fluorescent reagent based on 5(6)-carbonylated rhodamine 110. Maleimide can be labeled by forming a stable thioester structure through an affinity addition reaction with a thiol group (-SH) (Ex/Em = 502/527 nm).
|
- HY-D3291
-
|
|
Fluorescent Dyes
|
|
IR 680LT Maleimide is a near-infrared low-band fluorescence dye, composed of the IR 680LT dye core and maleimide groups. IR 680LT Maleimide is used for specifically labeling biologically active molecules containing sulfhydryl groups (Ex/Em = 679 nm/694 nm).
|
- HY-D3056
-
|
|
Fluorescent Dyes
|
|
5(6)-Rhodamine 6G maleimide is a maleimide-based fluorescent reagent based on Rhodamine 6G (HY-D0309). Maleimide can be labeled by forming a stable thioester structure through an affinity addition reaction with a thiol group (-SH) (Ex/Em = 526/547 nm).
|
- HY-D2763
-
|
|
Fluorescent Dyes
|
|
BP Fluor 532 maleimide is a photostable, bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 dye can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry.
Maleimide is the most popular sulfhydryl-reactive group for conjugating the dye to a thiol group on a protein, oligonucleotide thiophosphate, or low molecular weight ligand. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form a stable thioether bond. The resulting conjugates exhibit brighter fluorescence and greater photostability than the conjugates of many other spectrally similar fluorophores.
|
- HY-D3242
-
|
FD-1080-MAL
|
Fluorescent Dyes
|
|
FD-1080 Maleimide (FD-1080-MAL) is a fluorophore with both excitation and emission in the NIR-II region (Ex=1064 nm, Em=1080 nm). FD-1080 can be used for in vivo imaging .
|
- HY-D2530
-
|
|
Fluorescent Dyes
|
|
Cy5-PEG3400-SH is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
- HY-D2883A
-
|
Rhodamine B-PEG600-SH
|
Fluorescent Dyes
|
|
RB-PEG600-SH (Rhodamine B-PEG600-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .
|
- HY-D2883B
-
|
Rhodamine B-PEG1000-SH
|
Fluorescent Dyes
|
|
RB-PEG1000-SH (Rhodamine B-PEG1000-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .
|
- HY-D2883C
-
|
Rhodamine B-PEG2000-SH
|
Fluorescent Dyes
|
|
RB-PEG2000-SH (Rhodamine B-PEG2000-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .
|
- HY-D2883H
-
|
Rhodamine B-PEG10000-SH
|
Fluorescent Dyes
|
|
RB-PEG10000-SH (Rhodamine B-PEG10000-SH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and sulfhydryl (SH). SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds (Ex/Em=546/610 nm) .
|
- HY-D2512
-
|
|
Fluorescent Dyes
|
|
Cy3-PEG5000-SH is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
|
- HY-D2557
-
|
|
Fluorescent Dyes
|
|
Cy5.5-PEG3400-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
- HY-D2885H
-
|
Rhodamine B-PEG10000-Mal
|
Fluorescent Dyes
|
|
RB-PEG10000-Mal (Rhodamine B-PEG10000-Mal) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG10000-Mal can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
- HY-D2885E
-
|
Rhodamine B-PEG5000-Mal
|
Fluorescent Dyes
|
|
RB-PEG5000-Mal (Rhodamine B-PEG5000-Mal) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG5000-Mal can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
- HY-D2559
-
|
|
Fluorescent Dyes
|
|
Cy5.5-PEG10000-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
- HY-D2558
-
|
|
Fluorescent Dyes
|
|
Cy5.5-PEG5000-SH is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
|
- HY-D2885
-
|
Rhodamine B-PEG400-Mal
|
Fluorescent Dyes
|
|
RB-PEG400-Mal (Rhodamine B-PEG400-Mal) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG400-Mal can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
- HY-D2885A
-
|
Rhodamine B-PEG600-Mal
|
Fluorescent Dyes
|
|
RB-PEG600-Mal (Rhodamine B-PEG600-Mal) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG600-Mal can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
- HY-D2885C
-
|
Rhodamine B-PEG2000-Mal
|
Fluorescent Dyes
|
|
RB-PEG2000-Mal (Rhodamine B-PEG2000-Mal) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG2000-Mal can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
- HY-D2885B
-
|
Rhodamine B-PEG1000-Mal
|
Fluorescent Dyes
|
|
RB-PEG1000-Mal (Rhodamine B-PEG1000-Mal) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG1000-Mal can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
- HY-D2885D
-
|
Rhodamine B-PEG3400-Mal
|
Fluorescent Dyes
|
|
RB-PEG3400-Mal (Rhodamine B-PEG3400-Mal) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and Maleimide (HY-W007324) (Mal). RB-PEG3400-Mal can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm) .
|
- HY-D1390A
-
|
|
Fluorescent Dyes
|
|
Sulfo-Cy5-Mal is a fluorescent dye derivative composed of a CY5 dye and a maleimide functional group. Sulfo-Cy5-Mal specifically covalently binds to thiol-containing (-SH) biomolecules. Sulfo-Cy5-Mal can be used for protein labeling, antibody conjugation, molecular imaging, and drug delivery studies (Ex/Em = 633 nm/670 nm) .
|
- HY-D1390
-
|
|
Fluorescent Dyes
|
|
Sulfo-Cy5-Mal potassium is a fluorescent dye derivative composed of a CY5 dye and a maleimide functional group. Sulfo-Cy5-Mal potassium specifically covalently binds to thiol-containing (-SH) biomolecules. Sulfo-Cy5-Mal potassium can be used for protein labeling, antibody conjugation, molecular imaging, and drug delivery studies (Ex/Em = 633 nm/670 nm) .
|
- HY-173639
-
|
|
Fluorescent Dyes
|
|
AZD0516 is a first-in-class antibody-drug conjugate (ADC) targeting six-transmembrane epithelial antigen of the prostate-2 (STEAP2). The anti-STEAP2 monoclonal antibody (mAb) is conjugated via interchain cysteines to a maleimide-reactive, β-glucuronidase-cleavable linker (HY-173635) bearing the topoisomerase 1 inhibitor, Exatecan (HY-13631). AZD0516 can be used for the study of prostate cancer .
|
- HY-13631EG
-
|
MC-GGFG-DXD
|
Fluorescent Dyes
|
|
Deruxtecan (GMP) (MC-GGFG-DXD (GMP)) is Deruxtecan (HY-13631E) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing Trastuzumab deruxtecan (HY-138298A) and Patritumab deruxtecan (HY-P99813) .
|
- HY-143218
-
TPE-MI
Maximum Cited Publications
14 Publications Verification
Tetraphenylethene maleimide
|
Fluorescent Dyes
|
|
TPE-MI (Tetraphenylethene maleimide) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasites Plasmodium falciparum .
|
- HY-42360G
-
|
|
Fluorescent Dyes
|
|
SMCC (GMP) is the GMP level of SMCC (HY-42360). GMP guidelines are used to produce SMCC (HY-42360) (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. SMCC (GMP) is a protein crosslinker. SMCC (GMP) contains an amine-reactive N-hydroxysuccinimide ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses.
|
- HY-DY1024
-
|
|
Fluorescent Dyes
|
TPE-MI (Tetraphenylethene maleimide) (solution) is a thiol probe for measuring unfolded protein load and proteostasis in cells (the excitation wavelength is 350 nm and the emission wavelength is 470 nm). TPE-MI can report imbalances in proteostasis in induced pluripotent stem cell models of Huntington disease, as well as cells transfected with mutant Huntington exon 1 before the formation of visible aggregates. TPE-MI also detects protein damage following dihydroartemisinin research of the malaria parasitesPlasmodium falciparum .
Solvent and concentration: DMSO: 10 mM
|
- HY-D1565
-
|
|
Fluorescent Dyes
|
|
Cy7.5 maleimide is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
- HY-D1323
-
|
Cy5.5 maleimide chloride
|
Fluorescent Dyes
|
|
Cyanine5.5 maleimide chloride is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
- HY-DY1067
-
|
|
Fluorescent Dyes
|
Cy5 maleimide (solution) is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
Solvent and concentration: DMSO: 10 mM
|
| Cat. No. |
Product Name |
Type |
-
- HY-144004
-
|
DSPE-PEG2000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] ammonium
|
Biochemical Assay Reagents
|
|
DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents .
|
-
- HY-140739
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-Maleimide sodium (purity>95%) is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide sodium (purity>95%) can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration .
|
-
- HY-166648
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG2000-Maleimide sodium (purity>99%) is a functional lipid component and a thiol-reactive crosslinker. DSPE-PEG2000-Maleimide sodium (purity>99%) undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG2000-RGD. DSPE-PEG2000-Maleimide sodium (purity>99%) is applicable to research on drug delivery .
|
-
- HY-140740
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG5000-Maleimide, is a linker lipid containing DSPE phospholipid and Maleimide. DSPE-PEG-Maleimide is used in the synthesis of liposomes, including HELDC liposomes, sterically stabilized liposomes, and immunoliposomes .
|
-
- HY-W808757
-
|
|
Biochemical Assay Reagents
|
|
Biotin-maleimide is a biotinylated biochemical detection reagent that acts as a thiol-specific probe. Biotin-maleimide can also be used to prepare biotin-conjugated polychelators .
|
-
- HY-144004A
-
|
DSPE-PEG5000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-5000] ammonium
|
Biochemical Assay Reagents
|
|
DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents . DSPE-PEG5000-Mal ammonium contains PEG5000.
|
-
- HY-168940B
-
|
|
Biochemical Assay Reagents
|
|
NH2-PEG2000-COOH is a heterofunctional polyethylene glycol with one amino terminal group and one carboxyl terminal group. NH2-PEG2000-COOH reacts with N-succinimidyl-6-maleimidohexanoate to introduce a maleimide terminal group, followed by conjugation with thiolated RGD peptide via a thiol-maleimide coupling reaction to synthesize RGD-PEG-COOH. NH2-PEG2000-COOH can be used in cancer research .
|
-
- HY-166990
-
|
MeO-PEG5000-Mal
|
Biochemical Assay Reagents
|
|
Methoxypolyethylene glycol maleimide 5000 (MeO-PEG-Mal) is a protein PEGylation reagent.
|
-
- HY-W441004
-
|
|
Biochemical Assay Reagents
|
|
DSPE-Thiol is a phophalipid capped with thiol group. The thiol capped head can selectively react with maleimide. DSPE-Thiol can also be used for the preparation of phospholipid dimers .
|
-
- HY-174921A
-
|
|
Biochemical Assay Reagents
|
|
Maleimide-PEG2000-COOH is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
|
-
- HY-W441009A
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG3400-Maleimide ammonium can be used in drug delivery research .
|
-
- HY-W1048661E
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG2000-maleimide is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG2000-maleimide anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
- HY-D1364
-
|
|
Biochemical Assay Reagents
|
|
Pyrene maleimide is a polyaromatic fluorescent hydrocarbon with a termininal maleimide group. The maleimide group will react with a thiol group to form a covalent bond.
|
-
- HY-W017588
-
|
|
Biochemical Assay Reagents
|
|
N-(2-Hydroxyethyl)maleimide is a cross-linker. N-(2-Hydroxyethyl)maleimide is used for chemical synthesis .
|
-
- HY-W1048555A
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG2000-SCM is a heterobifunctional PEG crosslinker bearing maleimide and succinimidyl carboxymethyl ester functional groups. MMal-PEG2000-SCM conjugates the F3 peptide to nanoparticles: the SCM group reacts with amino groups on the nanoparticle surface to form amide groups, while the MAL group reacts with thiol groups of the F3 peptide to form carbon-sulfur bonds. Mal-PEG-SCM enables unidirectional addition of linkers, ensuring that appropriate functional groups are available for RGD incorporation. Mal-PEG2000-SCM can be used in the development of nanoparticles targeting specific tumor cells .
|
-
- HY-W441009B
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG1000-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG1000-Maleimide ammonium can be used in drug delivery research .
|
-
- HY-W1048851B
-
|
4-Arm-PEG10000-Mal
|
Biochemical Assay Reagents
|
|
4-Arm-PEG10000-Maleimide (4-Arm-PEG10000-Mal) is a four-arm star-shaped multifunctional PEG crosslinker with an average molecular weight of 10 kDa and maleimide terminal groups. 4-Arm-PEG10000-Maleimide efficiently conjugates biomolecules via thiol-Michael reaction, and is widely used in protein modification, antibody-drug conjugation and biomaterial preparation .
|
-
- HY-W1048553A
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG2000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W879049
-
|
DBCO-NHCO-PEG3-maleimide
|
Biochemical Assay Reagents
|
|
DBCO-PEG3-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG3-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
|
-
- HY-174953B
-
|
|
Biochemical Assay Reagents
|
|
TPP-PEG3400-Mal is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-174953A
-
|
|
Biochemical Assay Reagents
|
|
TPP-PEG2000-Mal is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-W190755
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG4-Mal is a PEG derivative with maleimide groups at both ends. Maleimide is a functional group that can undergo Michael addition reactions with sulfhydryl groups (–SH) and can be used for bioconjugation .
|
-
- HY-W011692
-
-
- HY-W1048553B
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG3400-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048553C
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG5000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-W1048661A
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG5000-maleimide is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG5000-maleimide anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
- HY-W1048661
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG1000-maleimide is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG1000-maleimide anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
- HY-174927E
-
|
DBCO-PEG3400-Mal
|
Biochemical Assay Reagents
|
|
DBCO-PEG3400-Maleimide (DBCO-PEG3400-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG3400-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927B
-
|
DBCO-PEG600-Mal
|
Biochemical Assay Reagents
|
|
DBCO-PEG600-Maleimide (DBCO-PEG600-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG600-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927A
-
|
DBCO-PEG400-Mal
|
Biochemical Assay Reagents
|
|
DBCO-PEG400-Maleimide (DBCO-PEG400-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG400-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927D
-
|
DBCO-PEG2000-Mal
|
Biochemical Assay Reagents
|
|
DBCO-PEG2000-Maleimide (DBCO-PEG2000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG2000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927H
-
|
DBCO-PEG10000-Mal
|
Biochemical Assay Reagents
|
|
DBCO-PEG10000-Maleimide (DBCO-PEG10000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG10000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174885B
-
|
|
Biochemical Assay Reagents
|
|
Acrylate-PEG3400-Maleimide is a PEG derivative containing an acrylate functional group, a PEG chain, and a maleimide group, which can be used for drug delivery .
|
-
- HY-W879036
-
|
|
Biochemical Assay Reagents
|
|
DBCO-PEG8-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG8-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
|
-
- HY-W1048851C
-
|
4-Arm-PEG20000-Mal
|
Biochemical Assay Reagents
|
|
4-Arm-PEG20000-Maleimide can be used for site-specific protein and peptide modification and can be used for drug delivery .
|
-
- HY-133540G
-
|
Maleimido-mono-amide-DOTA
|
Biochemical Assay Reagents
|
|
Maleimide-DOTA (Maleimido-mono-amide-DOTA) (GMP) is Maleimide-DOTA (HY-133540) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
- HY-W591465
-
|
4-Arm-PEG2000-Mal
|
Biochemical Assay Reagents
|
|
4-Arm-PEG2000-Maleimide (4-Arm-PEG2000-Mal) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
-
- HY-W440718C
-
|
|
Biochemical Assay Reagents
|
|
Cholesterol-PEG10000-Mal is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-174953
-
|
|
Biochemical Assay Reagents
|
|
TPP-PEG1000-Mal is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-W1048555B
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG3400-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG3400-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
-
- HY-W1048553
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG1000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
-
- HY-157920
-
|
N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine
|
Biochemical Assay Reagents
|
|
Biotin-PE-maleimide (N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine) is a bulky, membrane-impermeable, sulfhydryl-containing reagent with a relatively large molecular size. Biotin-PE-maleimide can be used for biotin labeling (such as thiol groups) and detection of proteins or other biomolecules .
|
-
- HY-167036C
-
|
|
Biochemical Assay Reagents
|
|
DMG-PEG5000-Mal is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG5000-Mal can be used for drug delivery .
|
-
- HY-159674
-
|
N-Tetamine-polySarcosine45-Maleimide
|
Biochemical Assay Reagents
|
|
N-Tetamine-pSar45-Maleimide (N-Tetamine-polySarcosine45-Maleimide) is a pSar-lipid derivative. As a hydrophilic alternative to PEG, N-Tetamine-pSar45-Maleimide can be used in drug delivery research .
|
-
- HY-W441009C
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG4000-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG4000-Maleimide ammonium can be used in drug delivery research .
|
-
- HY-W441009H
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG40000-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG40000-Maleimide ammonium can be used in drug delivery research .
|
-
- HY-W441009D
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG10000-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG10000-Maleimide ammonium can be used in drug delivery research .
|
-
- HY-W1048661H
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG3400-maleimide is a PEG derivative consisting of a linear PEG chain with biotin attached to one end and maleimide modified to the other end. Biotin-PEG3400-maleimide anchors drugs or targeting ligands to liposomes or polymer nanocarriers through the maleimide end, and the biotin end is used for in vitro purification or in vivo targeted release .
|
-
- HY-157919
-
|
N-6-(Biotinylamino)hexanoyl-N'-[2-(N-maleimido)ethyl]piperazine, hydrochloride
|
Biochemical Assay Reagents
|
|
Biotin-PEAC5-maleimide hydrochloride is a biochemical assay reagent, and can be used in biotin-PEAC5-maleimide (BPM)-labeling assay to assess modification of protein thiols by electrophiles .
|
-
- HY-W739513
-
- HY-174927
-
|
DBCO-PEG5000-Mal
|
Biochemical Assay Reagents
|
|
DBCO-PEG5000-Maleimide (DBCO-PEG5000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG5000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
- HY-174927C
-
|
DBCO-PEG1000-Mal
|
Biochemical Assay Reagents
|
|
DBCO-PEG1000-Maleimide (DBCO-PEG1000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG1000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
- HY-174885C
-
|
|
Biochemical Assay Reagents
|
|
Acrylate-PEG5000-Maleimide is a PEG derivative containing an acrylate functional group, a PEG chain, and a maleimide group, which can be used for drug delivery .
|
- HY-174885
-
|
|
Biochemical Assay Reagents
|
|
Acrylate-PEG1000-Maleimide is a PEG derivative containing an acrylate functional group, a PEG chain, and a maleimide group, which can be used for drug delivery .
|
- HY-174885A
-
|
|
Biochemical Assay Reagents
|
|
Acrylate-PEG2000-Maleimide is a PEG derivative containing an acrylate functional group, a PEG chain, and a maleimide group, which can be used for drug delivery .
|
- HY-168938
-
|
|
Biochemical Assay Reagents
|
|
Poly(ethylene glycol) methyl ether maleimide (Mn 2000) is a polyethylene glycol containing Maleimide (HY-W007324). Due to the Maleimide functional group, Poly(ethylene glycol) methyl ether maleimide (Mn 2000) can be used to conjugate biomolecules containing thiol groups.
|
- HY-171561G
-
|
|
Biochemical Assay Reagents
|
|
DOTAM-Maleimide triTFA (GMP) is DOTAM-Maleimide triTFA (HY-171561) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOTAM-Maleimide triTFA is a bifunctional chelator .
|
- HY-W1048851A
-
|
4-Arm-PEG5000-Mal
|
Biochemical Assay Reagents
|
|
4-Arm-PEG5000-Maleimide can be used for site-specific protein and peptide modification and can be used for drug delivery .
|
- HY-W1048851D
-
|
4-Arm-PEG40000-Mal
|
Biochemical Assay Reagents
|
|
4-Arm-PEG40000-Maleimide can be used for site-specific protein and peptide modification and can be used for drug delivery .
|
- HY-174921B
-
|
|
Biochemical Assay Reagents
|
|
Maleimide-PEG3400-COOH is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
|
- HY-174921C
-
|
|
Biochemical Assay Reagents
|
|
Maleimide-PEG5000-COOH is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
|
- HY-174921
-
|
|
Biochemical Assay Reagents
|
|
Maleimide-PEG1000-COOH is a PEG derivative composed of Maleimide (HY-W007324), PEG units and carboxyl (-COOH). Carboxyl can easily form a stable amide bond with amino groups or an ester bond with hydroxyl groups. Maleimide forms a stable thioether bond with sulfhydryl (-SH) .
|
- HY-174961
-
|
Fmoc-NH-PEG1000-Mal
|
Biochemical Assay Reagents
|
|
Fmoc-PEG1000-Maleimide (Fmoc-NH-PEG1000-Mal) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-174961C
-
|
Fmoc-NH-PEG5000-Mal
|
Biochemical Assay Reagents
|
|
Fmoc-PEG5000-Maleimide (Fmoc-NH-PEG5000-Mal) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-W087027A
-
|
|
Biochemical Assay Reagents
|
|
Maleimide-NOTA (TFA)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic NOTA derivative used for tumor pre-targeting. Maleimide-NOTA (TFA) can be used for conjugation of peptides and radionuclides.
|
- HY-W591618D
-
|
4-Arm-PEG3400-Mal
|
Biochemical Assay Reagents
|
|
4-Arm-PEG3400-Maleimide (4-Arm-PEG3400-Mal) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-W591618A
-
|
4-Arm-PEG400-Mal
|
Biochemical Assay Reagents
|
|
4-Arm-PEG400-Maleimide (4-Arm-PEG400-Mal) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-W591618C
-
|
4-Arm-PEG1000-Mal
|
Biochemical Assay Reagents
|
|
4-Arm-PEG1000-Maleimide (4-Arm-PEG1000-Mal) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-W190746
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG1-Mal is a PEG derivative with maleimide groups at both ends. Maleimide is a functional group that can undergo Michael addition reactions with sulfhydryl groups (–SH) and can be used for bioconjugation .
|
- HY-W1048555D
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG10000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG10000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
- HY-W1048555
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG1000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG1000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
- HY-W1048553H
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG40000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
- HY-W1048553E
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG20000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
- HY-W1048553D
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG10000-NH2TFA is a linear heterobifunctional PEG product with maleimide and NH2 groups. The maleimide can react with thiols, SH, sulfhydryls or sulfhydryls, and the amine can react with carboxylic acids or activated NHS esters .
|
- HY-167036A
-
|
|
Biochemical Assay Reagents
|
|
DMG-PEG1000-Mal is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG1000-Mal can be used for drug delivery .
|
- HY-W441009E
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG20000-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG20000-Maleimide ammonium can be used in drug delivery research .
|
- HY-174961B
-
|
Fmoc-NH-PEG3400-Mal
|
Biochemical Assay Reagents
|
|
Fmoc-PEG3400-Maleimide (Fmoc-NH-PEG3400-Mal) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-174961A
-
|
Fmoc-NH-PEG2000-Mal
|
Biochemical Assay Reagents
|
|
Fmoc-PEG2000-Maleimide (Fmoc-NH-PEG2000-Mal) is a PEG derivative with an Fmoc protecting group and a Maleimide (HY-W007324) reactive group. Fmoc is a commonly used amino protecting group that protects the amino group from unwanted reactions until it is removed for a specific coupling reaction. Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-W591618B
-
|
4-Arm-PEG600-Mal
|
Biochemical Assay Reagents
|
|
4-Arm-PEG600-Maleimide (4-Arm-PEG600-Mal) is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-174941
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG18-acid is a PEG derivative modified with maleimide groups. Maleimide is a functional group that can undergo Michael addition reaction with sulfhydryl (–SH) groups and can be used for bioconjugation.
|
- HY-174953D
-
|
|
Biochemical Assay Reagents
|
|
TPP-PEG10000-Mal is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
- HY-174953C
-
|
|
Biochemical Assay Reagents
|
|
TPP-PEG5000-Mal is a PEG derivative composed of triphenyl phosphate (TPP), PEG units, and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
- HY-W1048555H
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG40000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG40000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
- HY-W1048555C
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG5000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG5000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
- HY-W1048555E
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG20000-SCM is a linear hetero-bifunctional PEG product with maleimide and succinimidyl NHS ester groups. Mal-PEG20000-SCM is an important cross-linker with PEG chains. Maleimide reacts with thiols, SH, sulfhydryls or sulfhydryls, and SCM stands for succinimidyl carboxymethyl ester, which reacts with primary amines. Maleimide contains a reactive C=C double bond and is sensitive to light or oxygen .
|
- HY-W1052492
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG2000-Mal is a conjugate composed of DPPE, PEG chains, and maleimide (Mal). The maleimide group in DPPE-PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
- HY-W1052227A
-
|
|
Biochemical Assay Reagents
|
|
DMPE-PEG3400-Mal is a conjugate composed of DMPE, PEG chains, and maleimide (Mal). The maleimide group in DMPE-PEG3400-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
- HY-183126A
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG2000-Mal is a conjugate composed of DSG, PEG chains, and maleimide (Mal). The maleimide group in DSG-PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
- HY-183126B
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG3400-Mal is a conjugate composed of DSG, PEG chains, and maleimide (Mal). The maleimide group in DSG-PEG3400-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
- HY-183126D
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG10000-Mal is a conjugate composed of DSG, PEG chains, and maleimide (Mal). The maleimide group in DSG-PEG10000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
- HY-W1052227C
-
|
|
Biochemical Assay Reagents
|
|
DMPE-PEG1000-Mal is a conjugate composed of DMPE, PEG chains, and maleimide (Mal). The maleimide group in DMPE-PEG1000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
- HY-W1052227B
-
|
|
Biochemical Assay Reagents
|
|
DMPE-PEG5000-Mal is a conjugate composed of DMPE, PEG chains, and maleimide (Mal). The maleimide group in DMPE-PEG5000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
- HY-W1052492C
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG1000-Mal is a conjugate composed of DPPE, PEG chains, and maleimide (Mal). The maleimide group in DPPE-PEG1000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
- HY-W1052492B
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG5000-Mal is a conjugate composed of DPPE, PEG chains, and maleimide (Mal). The maleimide group in DPPE-PEG5000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
- HY-W1052227D
-
|
|
Biochemical Assay Reagents
|
|
DMPE-PEG10000-Mal is a conjugate composed of DMPE, PEG chains, and maleimide (Mal). The maleimide group in DMPE-PEG10000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
- HY-W1052492A
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG3400-Mal is a conjugate composed of DPPE, PEG chains, and maleimide (Mal). The maleimide group in DPPE-PEG3400-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
- HY-167036D
-
|
|
Biochemical Assay Reagents
|
|
DMG-PEG10000-Mal is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG10000-Mal can be used for drug delivery .
|
- HY-W1052492D
-
|
|
Biochemical Assay Reagents
|
|
DPPE-PEG10000-Mal is a conjugate composed of DPPE, PEG chains, and maleimide (Mal). The maleimide group in DPPE-PEG10000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
- HY-183126C
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG5000-Mal is a conjugate composed of DSG, PEG chains, and maleimide (Mal). The maleimide group in DSG-PEG5000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
- HY-167036B
-
|
|
Biochemical Assay Reagents
|
|
DMG-PEG3400-Mal is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG3400-Mal can be used for drug delivery .
|
- HY-W1052227
-
|
|
Biochemical Assay Reagents
|
|
DMPE-PEG2000-Mal is a conjugate composed of DMPE, PEG chains, and maleimide (Mal). The maleimide group in DMPE-PEG2000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
- HY-183126
-
|
|
Biochemical Assay Reagents
|
|
DSG-PEG1000-Mal is a conjugate composed of DSG, PEG chains, and maleimide (Mal). The maleimide group in DSG-PEG1000-Mal can undergo a specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), enabling targeted modification of liposomes/nanoparticles.
|
- HY-166990C
-
- HY-166990A
-
|
MeO-PEG10000-Mal
|
Biochemical Assay Reagents
|
|
Methoxypolyethylene glycol maleimide 10000 (MeO-PEG10000-Mal) is a biochemical reagent .
|
- HY-166990B
-
|
MeO-PEG2000-Mal
|
Biochemical Assay Reagents
|
|
Methoxypolyethylene glycol maleimide 2000 (MeO-PEG2000-Mal) is a protein PEGylation reagent .
|
- HY-163790
-
- HY-163789
-
|
|
Biochemical Assay Reagents
|
|
Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
- HY-W068119A
-
|
2-Maleimidoethylamine hydrochloride
|
Biochemical Assay Reagents
|
|
N-(2-Aminoethyl)maleimide (2-Maleimidoethylamine) hydrochloride is a selective covalent binding agent for thiol groups (RSGs), covalently binding to thiols via an irreversible thioether bond to prepare MMP-2-sensitive nanosystems. Under near-neutral conditions, the maleimide group in N-(2-Aminoethyl)maleimide hydrochloride binds to thiol groups via a nucleophilic addition reaction, and can be used to modify polymers or biological interfaces, enhancing mucosal adhesion and regulating the surface charge of biological interfaces. N-(2-Aminoethyl)maleimide hydrochloride can optimize the adhesion performance of drug delivery carriers and cell interactions with biological interfaces, and is applied in transmucosal drug delivery systems (such as drug carriers for oral and bladder sites) and biomaterial surface engineering research, providing support for tissue implantation, regeneration, and related drug delivery .
|
- HY-W011433
-
|
|
Biochemical Assay Reagents
|
|
N-(1-Pyrenyl)maleimide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
- HY-D0975
-
|
|
Biochemical Assay Reagents
|
|
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.
|
- HY-155902E
-
|
Maleimide-PEG20000-Hydroxy
|
Biochemical Assay Reagents
|
|
Mal-PEG20000-OH (Maleimide-PEG20000-Hydroxy) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG20000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .
|
- HY-155902H
-
|
Maleimide-PEG40000-Hydroxy
|
Biochemical Assay Reagents
|
|
Mal-PEG40000-OH (Maleimide-PEG40000-Hydroxy) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG40000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .
|
- HY-155902D
-
|
Maleimide-PEG10000-Hydroxy
|
Biochemical Assay Reagents
|
|
Mal-PEG10000-OH (Maleimide-PEG10000-Hydroxy) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG10000-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .
|
- HY-155902C
-
|
Maleimide-PEG3400-Hydroxy
|
Biochemical Assay Reagents
|
|
Mal-PEG3400-OH (Maleimide-PEG3400-Hydroxy) is a linear heteroterminal bifunctional PEG product with maleimide and hydroxyl groups. Mal-PEG3400-OH can be used as a macroinitiator to obtain amphiphilic diblock copolymers through ring-opening polymerization of Lactate (Lactic Acid) (HY-B2227). Nanoparticles prepared using amphiphilic block copolymers can form active drug delivery systems .
|
- HY-174914
-
|
|
Biochemical Assay Reagents
|
|
Biotin-PEG4-mal is a PEG derivative composed of Biotin, 4 PEG units and Maleimide. Biotin can form a stable non-covalent bond with streptavidin.
|
- HY-W1049129D
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG40000-mal is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG40000-mal can be used for drug delivery .
|
- HY-W020780C
-
|
mPEG3400-Maleimide
|
Biochemical Assay Reagents
|
|
mPEG3400-Mal is a PEG derivative used for thiol pegylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
- HY-W1049129C
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG20000-mal is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG20000-mal can be used for drug delivery .
|
- HY-W020780A
-
|
mPEG350-Maleimide
|
Biochemical Assay Reagents
|
|
mPEG350-Mal is a PEG derivative used for thiol PEGylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
- HY-W1049129B
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG10000-mal is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG10000-mal can be used for drug delivery .
|
- HY-W020780B
-
|
mPEG750-Maleimide
|
Biochemical Assay Reagents
|
|
mPEG750-Mal is a PEG derivative used for thiol pegylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
- HY-W1048552
-
|
|
Biochemical Assay Reagents
|
|
Mal-PEG1000-mal is a linear bifunctional PEG reagent with reactive maleimide groups. Mal-PEG1000-mal can be used for drug delivery .
|
- HY-W440897
-
|
|
Biochemical Assay Reagents
|
|
DSPE-PEG3400-SH is a maleimide reactive PEG lipid. The amphiphilic polymer forms lipid bilayer in water and can be used to prepare liposomes for drug nanocarriers to deliver mRNA, DNA or siRNA.
|
- HY-179205B
-
|
|
Biochemical Assay Reagents
|
|
PLA5000-PEG3400-MAL is a PEG derivative with a maleimide group at the end. PLA5000-PEG3400-MAL can be used for drug delivery .
|
- HY-179198C
-
|
|
Biochemical Assay Reagents
|
|
PLA2000-PEG5000-MAL is a PEG derivative with a maleimide group at the end. PLA2000-PEG5000-MAL can be used for drug delivery .
|
- HY-W440722
-
|
|
Biochemical Assay Reagents
|
|
Cholesterol-PEG1000-Thiol is a PEGylated lipid that forms micelles in water and can be used to prepare liposomes or nanoparticles as drug delivery systems. The thiol moiety reacts with maleimide to form a stable thioether bond .
|
- HY-179198A
-
|
|
Biochemical Assay Reagents
|
|
PLA2000-PEG2000-MAL is a PEG derivative with a maleimide group at the end. PLA2000-PEG2000-MAL can be used for drug delivery .
|
- HY-179205
-
|
|
Biochemical Assay Reagents
|
|
PLA5000-PEG1000-MAL is a PEG derivative with a maleimide group at the end. PLA5000-PEG1000-MAL can be used for drug delivery .
|
- HY-179205C
-
|
|
Biochemical Assay Reagents
|
|
PLA5000-PEG5000-MAL is a PEG derivative with a maleimide group at the end. PLA5000-PEG5000-MAL can be used for drug delivery .
|
- HY-179198
-
|
|
Biochemical Assay Reagents
|
|
PLA2000-PEG1000-MAL is a PEG derivative with a maleimide group at the end. PLA2000-PEG1000-MAL can be used for drug delivery .
|
- HY-179206B
-
|
|
Biochemical Assay Reagents
|
|
PLA10000-PEG3400-MAL is a PEG derivative with a maleimide group at the end. PLA10000-PEG3400-MAL can be used for drug delivery .
|
- HY-179206
-
|
|
Biochemical Assay Reagents
|
|
PLA10000-PEG1000-MAL is a PEG derivative with a maleimide group at the end. PLA10000-PEG1000-MAL can be used for drug delivery .
|
- HY-179206A
-
|
|
Biochemical Assay Reagents
|
|
PLA10000-PEG2000-MAL is a PEG derivative with a maleimide group at the end. PLA10000-PEG2000-MAL can be used for drug delivery .
|
- HY-179205A
-
|
|
Biochemical Assay Reagents
|
|
PLA5000-PEG2000-MAL is a PEG derivative with a maleimide group at the end. PLA5000-PEG2000-MAL can be used for drug delivery .
|
- HY-179206C
-
|
|
Biochemical Assay Reagents
|
|
PLA10000-PEG5000-MAL is a PEG derivative with a maleimide group at the end. PLA10000-PEG5000-MAL can be used for drug delivery .
|
- HY-179198B
-
|
|
Biochemical Assay Reagents
|
|
PLA2000-PEG3400-MAL is a PEG derivative with a maleimide group at the end. PLA2000-PEG3400-MAL can be used for drug delivery .
|
- HY-W1048510B
-
|
|
Biochemical Assay Reagents
|
|
2-Arm PEG20000-Mal is a multi-arm PEG derivative with maleimide groups at each end of the 2 arms. 2-Arm PEG20000-Mal can be used for drug delivery .
|
- HY-W1048605C
-
|
|
Biochemical Assay Reagents
|
|
8-Arm PEG40000-Mal is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG40000-Mal can be used for drug delivery .
|
- HY-W1048510C
-
|
|
Biochemical Assay Reagents
|
|
2-Arm PEG40000-Mal is a multi-arm PEG derivative with maleimide groups at each end of the 2 arms. 2-Arm PEG40000-Mal can be used for drug delivery .
|
- HY-W441007
-
|
|
Biochemical Assay Reagents
|
|
DSPE-MAL is a phospholipid compound with a maleimide reactive group. DSPE-MAL contains two saturated fatty acids and can self-assemble in water to form a lipid bilayer. DSPE-MAL can be used to prepare liposomes as nanocarriers for active molecules .
|
- HY-W1048510D
-
|
|
Biochemical Assay Reagents
|
|
2-Arm PEG5000-Mal is a multi-arm PEG derivative with maleimide groups at each end of the two arms. 2-Arm PEG5000-Mal can be used for drug delivery .
|
- HY-W1048605B
-
|
|
Biochemical Assay Reagents
|
|
8-Arm PEG10000-Mal is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG10000-Mal can be used for drug delivery .
|
- HY-W1048605A
-
|
|
Biochemical Assay Reagents
|
|
8-Arm PEG20000-Mal is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG20000-Mal can be used for drug delivery .
|
- HY-W1048510A
-
|
|
Biochemical Assay Reagents
|
|
2-Arm PEG10000-Mal is a multi-arm PEG derivative with maleimide groups at each end of the 2 arms. 2-Arm PEG10000-Mal can be used for drug delivery .
|
- HY-W1048605
-
|
|
Biochemical Assay Reagents
|
|
8-Arm PEG5000-Mal is a multi-arm PEG derivative with maleimide groups at each end of the eight arms. 8-Arm PEG5000-Mal can be used for drug delivery .
|
- HY-155901
-
|
Maleimide-NH-PEG2000-amine TFA
|
Biochemical Assay Reagents
|
|
Mal-NH-PEG2000-NH2TFA is a PEG derivative that may be used for thiol PEGylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
- HY-174809A
-
|
|
Biochemical Assay Reagents
|
|
6-Arm-PEG600-Mal is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-174809E
-
|
|
Biochemical Assay Reagents
|
|
6-Arm-PEG5000-Mal is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-174809H
-
|
|
Biochemical Assay Reagents
|
|
6-Arm-PEG10000-Mal is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-174809
-
|
|
Biochemical Assay Reagents
|
|
6-Arm-PEG400-Mal is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-174809C
-
|
|
Biochemical Assay Reagents
|
|
6-Arm-PEG2000-Mal is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-174809D
-
|
|
Biochemical Assay Reagents
|
|
6-Arm-PEG3400-Mal is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-174809B
-
|
|
Biochemical Assay Reagents
|
|
6-Arm-PEG1000-Mal is a PEG derivative modified with Maleimide (HY-W007324), which forms a stable thioether bond with sulfhydryl (-SH). PEG modification can improve solubility and stability and reduce the immunogenicity of proteins and peptides .
|
- HY-W001851
-
|
N-Benzylmaleimide
|
Biochemical Assay Reagents
|
|
1-Benzylpyrrole-2,5-dione (N-Benzylmaleimide) is a heterocyclic compound containing a maleimide ring and a benzyl group. 1-Benzylpyrrole-2,5-dione can be used as a key reactant for the green chemical modification of cellulose nanocrystals (CNC).
|
- HY-W588728
-
|
|
Biochemical Assay Reagents
|
|
DBCO-PEG8-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
- HY-W588736
-
|
|
Biochemical Assay Reagents
|
|
DBCO-PEG23-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
- HY-W1048849B
-
|
4-Arm PEG-thiol (MW 10000)
|
Biochemical Assay Reagents
|
|
4-Arm PEG-SH (MW 10000) (4-Arm PEG-thiol (MW 10000)) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
|
- HY-W020780
-
|
mPEG5000-Maleimide
|
Biochemical Assay Reagents
|
|
mPEG5000-Mal (mPEG5000-Maleimide) is a PEG-derived selective covalent binding agent for sulfhydryl groups (RSGs), which can form irreversible thioether bonds with sulfhydryl groups under near-neutral conditions via the maleimide group. The mechanism of action of mPEG5000-Mal can be divided into two categories: firstly, as an enzyme modifier, it binds to target proteins through hydrophobic interactions, hydrogen bonds, and van der Waals forces, altering the protein's secondary structure; secondly, as a nanoparticle surface modifier, it covalently binds to sulfhydryl groups on the surface of red blood cells, changing the surface properties and morphology of the red blood cells, leading to their phagocytosis by macrophages of the reticuloendothelial system. mPEG5000-Mal can react with free cysteine in proteins, increasing the apparent molecular weight of the modified protein by 10-15 kDa for detection purposes. mPEG5000-Mal can enhance the thermal stability and catalytic activity of enzymes, and improve the macrophage targeting of nanoparticles, enabling targeted drug delivery. mPEG5000-Mal can be applied in enzyme engineering research in the food industry and in oncology, assisting radiotherapy by inhibiting tumor-associated macrophage infiltration and enhancing anti-tumor immune responses .
|
- HY-W1048849D
-
|
4-Arm PEG40000-thiol
|
Biochemical Assay Reagents
|
|
4-Arm PEG40000-SH (4-Arm PEG40000-thiol) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
|
- HY-W1048849A
-
|
4-Arm PEG5000-thiol
|
Biochemical Assay Reagents
|
|
4-Arm PEG5000-SH (4-Arm PEG5000-thiol) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
|
- HY-W1048849C
-
|
4-Arm PEG20000-thiol
|
Biochemical Assay Reagents
|
|
4-Arm PEG20000-SH (4-Arm PEG20000-thiol) is a multi-arm PEG derivative with thiol groups at each end of the four arms. The reactive free thiol, SH or sulfhydryl groups react selectively with maleimide and transition metal surfaces including gold and silver .
|
- HY-171337B
-
|
|
Biochemical Assay Reagents
|
|
C18-PEG5000-Mal is a conjugate composed of a octadecyl (C18 aliphatic chain), a PEG chain, and maleimide (Mal). C18-PEG5000-Mal combines the membrane compatibility of lipids with the specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183135
-
|
|
Biochemical Assay Reagents
|
|
C16-PEG2000-Mal is a conjugate composed of a hexadecyl (C16 aliphatic chain), a PEG chain, and maleimide (Mal). C16-PEG2000-Mal combines the membrane compatibility of lipids with the specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), making it suitable for research in biomaterial construction and drug delivery.
|
- HY-171337
-
|
|
Biochemical Assay Reagents
|
|
C18-PEG2000-Mal is a conjugate composed of a octadecyl (C18 aliphatic chain), a PEG chain, and maleimide (Mal). C18-PEG2000-Mal combines the membrane compatibility of lipids with the specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183135A
-
|
|
Biochemical Assay Reagents
|
|
C16-PEG3400-Mal is a conjugate composed of a hexadecyl (C16 aliphatic chain), a PEG chain, and maleimide (Mal). C16-PEG3400-Mal combines the membrane compatibility of lipids with the specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), making it suitable for research in biomaterial construction and drug delivery.
|
- HY-183135B
-
|
|
Biochemical Assay Reagents
|
|
C16-PEG5000-Mal is a conjugate composed of a hexadecyl (C16 aliphatic chain), a PEG chain, and maleimide (Mal). C16-PEG5000-Mal combines the membrane compatibility of lipids with the specific Michael addition reaction with thiol-containing (-SH) biomolecules (such as peptides, antibodies, and aptamers), making it suitable for research in biomaterial construction and drug delivery.
|
- HY-13631EG
-
|
MC-GGFG-DXD
|
Biochemical Assay Reagents
|
|
Deruxtecan (GMP) (MC-GGFG-DXD (GMP)) is Deruxtecan (HY-13631E) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing Trastuzumab deruxtecan (HY-138298A) and Patritumab deruxtecan (HY-P99813) .
|
- HY-W1048545H
-
|
Amine-PEG1000-Thiol hydrochloride
|
Biochemical Assay Reagents
|
|
H2N-PEG1000-SH (Amine-PEG1000-Thiol) hydrochloride is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG1000-SH hydrochloride is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
- HY-W1048545I
-
|
Amine-PEG3400-Thiol hydrochloride
|
Biochemical Assay Reagents
|
|
H2N-PEG3400-SH (Amine-PEG3400-Thiol) hydrochloride is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG3400-SH hydrochloride is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
- HY-W1048545E
-
|
Amine-PEG20000-Thiol hydrochloride
|
Biochemical Assay Reagents
|
|
H2N-PEG20000-SH (Amine-PEG20000-Thiol) hydrochloride is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG20000-SH hydrochloride is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
- HY-W1048545D
-
|
Amine-PEG10000-Thiol hydrochloride
|
Biochemical Assay Reagents
|
|
H2N-PEG10000-SH (Amine-PEG10000-Thiol) hydrochloride is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG10000-SH hydrochloride is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
- HY-W1048545A
-
|
Amine-PEG2000-Thiol hydrochloride
|
Biochemical Assay Reagents
|
|
H2N-PEG2000-SH (Amine-PEG2000-Thiol) hydrochloride is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG2000-SH hydrochloride is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
- HY-W1048545J
-
|
Amine-PEG40000-Thiol hydrochloride
|
Biochemical Assay Reagents
|
|
H2N-PEG40000-SH (Amine-PEG40000-Thiol) hydrochloride is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG40000-SH hydrochloride is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
- HY-42360G
-
|
|
Biochemical Assay Reagents
|
|
SMCC (GMP) is the GMP level of SMCC (HY-42360). GMP guidelines are used to produce SMCC (HY-42360) (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. SMCC (GMP) is a protein crosslinker. SMCC (GMP) contains an amine-reactive N-hydroxysuccinimide ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses.
|
- HY-W1048545C
-
|
Amine-PEG5000-Thiol hydrochloride
|
Biochemical Assay Reagents
|
|
H2N-PEG5000-SH (Amine-PEG5000-Thiol) hydrochloride is a linear heterobifunctional PEGylated product containing thiol and amine. H2N-PEG5000-SH hydrochloride is an important cross-linking or bioconjugation reagent with PEG chains. Thiol or SH, sulfhydryl or thiol selectively reacts with maleimide, OPSS, vinyl sulfone and transition metal surfaces (including gold, silver, etc.) .
|
| Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P4113
-
|
|
Peptides
|
Neurological Disease
|
|
TAT-NSF700 Fusion Peptide is a potent N-ethyl-maleimide-sensitive factor (NSF) inhibitor. TAT-NSF700 Fusion Peptide can readily permeate the cell membrane and interact with the intracellular organelle directly .
|
-
- HY-P1801
-
|
Cys-[HIV-Tat (47-57)]
|
HIV
Drug Derivative
|
Others
|
|
Cys-TAT(47-57) (Cys-[HIV-Tat (47-57)]), TAT (HY-P0281) derivative, is a Cysteine (HY-Y0337)-tagged cell-penetrating peptide (CPP) derived from the HIV TAT protein. Cys-TAT(47-57) can be used for the research for the research of drug delivery .
|
-
- HY-P11697
-
|
|
Drug Intermediate
|
Others
|
|
Fmoc-PNA-maleimide-OH is a Fmoc-protected functionalized peptide nucleic acid monomer featuring a maleimide group for thiol-reactive conjugation. Fmoc-PNA-maleimide-OH can be used in constructing PNA conjugates for molecular assembly applications.
|
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-W007324
-
-
-
- HY-N16290
-
|
|
Lipid
|
Biochemical Assay Reagents
|
|
Chol-PEG2000-maleimide is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
-
- HY-N16289
-
|
|
Lipid
|
Biochemical Assay Reagents
|
|
DSPE-PEG8 Maleimide sodium is a PEG lipid containing DSPE, a polyethylene glycol chain consisting of eight ethylene glycol units (PEG8), and a maleimide group (Mal). DSPE-PEG8 Maleimide sodium can be used to prepare lipid nanoparticles for drug delivery .
|
-
-
- HY-N16291
-
-
-
- HY-N16237
-
|
|
Lipid
|
Biochemical Assay Reagents
|
|
Chol-PEG1000-maleimide is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
-
- HY-N15951
-
|
|
Lipid
|
Biochemical Assay Reagents
|
|
C16 Ceramide-suc-PEG2K-maleimide is functionalized PEG lipid that can be used to synthesize lipid nanoparticles for drug delivery.
|
-
-
- HY-N16328
-
|
|
Structural Classification
Lipid
|
Fluorescent Dye
|
|
Cy7.5 maleimide chloride is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
-
- HY-N15791
-
|
|
Structural Classification
Lipid
|
Fluorescent Dye
|
|
Cyanine3.5 maleimide chloride is a CY dye. CY, short for Cyanine, is a compound consisting of two nitrogen atoms connected by an odd number of methyl units. Cyanine compounds have the characteristics of long wavelength, adjustable absorption and emission, high extinction coefficient, good water solubility and relatively simple synthesis . CY dyes are of en used for the labeling of proteins, antibodies and small molecular compounds. For the labeling of protein antibodies, the combination can be completed through a simple mixing reaction. Below, we introduce the labeling method of protein antibody labeling, which has certain reference significance .
|
-
-
- HY-W007324R
-
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-13631ES4
-
|
|
|
Deruxtecan-d5 is deuterium labeled Deruxtecan (HY-13631E). Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
|
-
-
- HY-13631ES3
-
|
|
|
Deruxtecan-d2 is the deuterium labeled Deruxtecan (HY-13631E) . Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
|
-
-
- HY-A0023AS2
-
|
|
|
Sulfo DBCO-PEG4-Maleimide TEA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
-
- HY-13631ES
-
|
|
|
Deruxtecan-d4 is deuterium labeled Deruxtecan (HY-13631E). Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
|
-
-
- HY-13631ES2
-
|
|
|
Deruxtecan-d4-1 is the deuterium labeled Adenosine Deruxtecan (HY-13631E) . Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-120770
-
|
|
|
DBCO
ADC Synthesis
|
|
DBCO-PEG4-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-116270
-
|
|
|
DBCO
ADC Synthesis
|
|
DBCO-Maleimide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . DBCO-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-151696
-
|
|
|
TCO
|
|
TCO-PEG3-maleimide (TCO-PEG3-NEM) is a click chemistry reagent. TCO-PEG3-maleimide efficiently binds TCO (trans-cyclooctene) moiety to thiol-containing molecules (such as antibodies, cysteine-containing peptides) .
|
-
- HY-156311
-
|
|
|
ADC Synthesis
BCN
|
|
BCN-endo-PEG2-maleimide is an ADC Linker containing 4 PEG units. BCN-endo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-141278
-
|
|
|
PROTAC Synthesis
Tetrazine
|
|
Methyltetrazine-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG4-maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-136104
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Methyltetrazine-Maleimide is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Methyltetrazine-Maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-134734
-
|
|
|
BCN
|
|
BCN-exo-PEG7-maleimide is an ADC Linker containing 7 PEG units. BCN-exo-PEG7-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-133399
-
|
|
|
Alkynes
PROTAC Synthesis
|
|
Alkyne-PEG4-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Alkyne-PEG4-maleimide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
|
-
- HY-140307
-
|
|
|
DBCO
PROTAC Synthesis
|
|
Sulfo DBCO-PEG4-Maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Sulfo DBCO-PEG4-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-W879048
-
|
|
|
DBCO
|
|
DBCO-PEG24-Maleimide contains a maleimide and a DBCO group. DBCO-PEG24-Maleimide can be used for thiol-containing biomolecule conjugations. DBCO-PEG24-Maleimide can be used in click chemistry with azide-bearing biomolecules .
|
-
- HY-W872575
-
|
|
|
TCO
PROTAC Synthesis
|
|
TCO4-PEG3-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG3-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
|
-
- HY-156322
-
|
|
|
BCN
|
|
BCN-exo-PEG3-maleimide is an ADC Linker containing 3 PEG units. BCN-exo-PEG3-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which enables the further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-133374
-
|
|
|
PROTAC Synthesis
DBCO
|
|
DBCO-PEG12-Maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-PEG12-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-140307A
-
|
|
|
DBCO
|
|
Sulfo DBCO-PEG4-Maleimide TEA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Sulfo DBCO-PEG4-Maleimide (TEA) is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-156320
-
|
|
|
BCN
|
|
BCN-exo-PEG2-maleimide is an ADC Linker containing 2 PEG units. BCN-exo-PEG2-maleimide contains the lyophilic bidentate macrocyclic ligand BCN, which allows for further synthesis of macrocyclic complexes. In click chemistry, BCN reacts with molecules containing azide groups to form stable triazoles in the absence of catalysts. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-141184
-
|
|
|
TCO
|
|
TCO-PEG9-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs .
|
-
- HY-156488
-
|
|
|
TCO
|
|
TCO-PEG7-Maleimide contains TCO groups, and can undergo specific "click" reactions with tetrazine groups.
|
-
- HY-156308
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Me-Tet-PEG4-Maleimide is an ADC Linker containing 4 PEG units. Me-Tet-PEG4-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-156392
-
|
|
|
TCO
PROTAC Synthesis
|
|
TCO4-PEG7-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG7-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
|
-
- HY-W879049
-
|
DBCO-NHCO-PEG3-maleimide
|
|
DBCO
|
|
DBCO-PEG3-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG3-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
|
-
- HY-156317
-
|
|
|
BCN
|
|
BCN-endo-PEG7-maleimide is an ADC Linker containing 7 PEG units. BCN-endo-PEG7-maleimide contains the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
|
-
- HY-156307
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Me-Tet-PEG3-Maleimide is an ADC Linker containing 3 PEG units. Me-Tet-PEG3-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-156312
-
|
|
|
ADC Synthesis
Tetrazine
|
|
Me-Tet-PEG8-Maleimide is an ADC Linker containing 8 PEG units. Me-Tet-PEG8-Maleimide can utilize its own Tetrazine group to undergo a specific inverse electron demand Diels-Alder reaction (iEDDA) with compounds with TCO groups. Its maleimide group (-Maleimide) degrades in aqueous media and has been used in drug delivery studies.
|
-
- HY-174927E
-
|
DBCO-PEG3400-Mal
|
|
DBCO
|
|
DBCO-PEG3400-Maleimide (DBCO-PEG3400-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG3400-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927B
-
|
DBCO-PEG600-Mal
|
|
DBCO
|
|
DBCO-PEG600-Maleimide (DBCO-PEG600-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG600-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927A
-
|
DBCO-PEG400-Mal
|
|
DBCO
|
|
DBCO-PEG400-Maleimide (DBCO-PEG400-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG400-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927D
-
|
DBCO-PEG2000-Mal
|
|
DBCO
|
|
DBCO-PEG2000-Maleimide (DBCO-PEG2000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG2000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927H
-
|
DBCO-PEG10000-Mal
|
|
DBCO
|
|
DBCO-PEG10000-Maleimide (DBCO-PEG10000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG10000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-W879036
-
|
|
|
DBCO
|
|
DBCO-PEG8-Maleimide is a PEG derivative consisting of DBCO, PEG units, and Maleimide (HY-W007324). NMaleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG8-Maleimide contains a DBCO group, which can undergo a strain-promoted alkyne-azide cycloaddition reaction (SPAAC) with molecules containing an azide group .
|
-
- HY-133475
-
|
|
|
TCO
PROTAC Synthesis
|
|
TCO-PEG5-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . TCO-PEG5-maleimide is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-W588728
-
|
|
|
DBCO
|
|
DBCO-PEG8-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
-
- HY-156391
-
|
|
|
TCO
|
|
TCO4-PEG2-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG2-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
|
-
- HY-W872575A
-
|
|
|
TCO
|
|
TCO4-PEG3-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG3-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
|
-
- HY-156391A
-
|
|
|
TCO
|
|
TCO4-PEG2-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG2-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
|
-
- HY-174927
-
|
DBCO-PEG5000-Mal
|
|
DBCO
|
|
DBCO-PEG5000-Maleimide (DBCO-PEG5000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG5000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-174927C
-
|
DBCO-PEG1000-Mal
|
|
DBCO
|
|
DBCO-PEG1000-Maleimide (DBCO-PEG1000-Mal) is a PEG derivative composed of DBCO, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DBCO-PEG1000-Maleimide contains a DBCO group and can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing an azide group .
|
-
- HY-157008
-
|
|
|
TCO
ADC Synthesis
|
|
(S)-TCO-PEG2-Maleimide is an ADC linker containing 2 PEG units. (S)-TCO-PEG2-Maleimide can use its own TCO group to perform an inverse electron demand Diels-Alder reaction (iEDDA) with molecules with Tetrazine groups.
|
-
- HY-133372
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DBCO-NHCO-PEG2-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG2-maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133373
-
|
|
|
DBCO
PROTAC Synthesis
|
|
DBCO-NHCO-PEG6-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . DBCO-NHCO-PEG6-maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
|
-
- HY-133468
-
|
|
|
PROTAC Synthesis
Tetrazine
|
|
Methyltetrazine-PEG6-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Methyltetrazine-PEG6-maleimide is a click chemistry reagent, it contains a Tetrazine group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing TCO groups.
|
-
- HY-133477
-
|
|
|
PROTAC Synthesis
TCO
|
|
(S)-TCO-PEG3-maleimide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . (S)-TCO-PEG3-maleimide is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
|
-
- HY-163789
-
|
|
|
DBCO
|
|
Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Desthiobiotin-PEG3-triazole-DBCO-sulfo-Maleimide is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups .
|
-
- HY-W588736
-
|
|
|
DBCO
|
|
DBCO-PEG23-amine is a PEG derivative consisting of DBCO, PEG units and an amino group (Amine). Maleimide forms a stable thioether bond with sulfhydryl (-SH). The amino group can react with other chemical groups (such as carboxyl, aldehyde, etc.) to form stable chemical bonds.
|
-
- HY-186171
-
|
|
|
Alkynes
|
|
Mal-(1R,2S,3R,4S)-himic acid-alkyne is a trifunctional click chemistry scaffold containing complementary functionalities for copper catalyzed azide-alkyne (CuAAC), thiol-Michael addition, and inverse electron demand Diels-Alder (iEDDA) click reactions .
|
-
- HY-183022
-
|
|
|
Azide
|
|
1-(3-Azidopropyl)-1H-pyrrole-2,5-dione is a maleimide derivative with a 3-azidopropyl substituent, used to introduce an azide functional group to bovine serum albumin (BSA). 1-(3-Azidopropyl)-1H-pyrrole-2,5-dione reacts with the free, solvent-accessible thiol group of BSA to produce azide-functionalized BSA, which is used in click chemistry to form a TLL-BSA hetero-dimer .
|
| Cat. No. |
Product Name |
|
Classification |
-
- HY-144004
-
|
DSPE-PEG2000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-2000] ammonium
|
|
Pegylated Lipids
|
|
DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents .
|
-
- HY-140739
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-Maleimide sodium (purity>95%) is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide sodium (purity>95%) can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration .
|
-
- HY-166648
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-Maleimide sodium (purity>99%) is a functional lipid component and a thiol-reactive crosslinker. DSPE-PEG2000-Maleimide sodium (purity>99%) undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG2000-RGD. DSPE-PEG2000-Maleimide sodium (purity>99%) is applicable to research on drug delivery .
|
-
- HY-140740
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG5000-Maleimide, is a linker lipid containing DSPE phospholipid and Maleimide. DSPE-PEG-Maleimide is used in the synthesis of liposomes, including HELDC liposomes, sterically stabilized liposomes, and immunoliposomes .
|
-
- HY-144004A
-
|
DSPE-PEG5000 Maleimide ammonium; 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-[maleimide(polyethylene glycol)-5000] ammonium
|
|
Pegylated Lipids
|
|
DSPE-PEG-Maleimide has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG-Maleimide extends blood circulation time and higher stability for encapsulated agents . DSPE-PEG5000-Mal ammonium contains PEG5000.
|
-
- HY-W441007
-
|
|
|
Phospholipids
|
|
DSPE-MAL is a phospholipid compound with a maleimide reactive group. DSPE-MAL contains two saturated fatty acids and can self-assemble in water to form a lipid bilayer. DSPE-MAL can be used to prepare liposomes as nanocarriers for active molecules .
|
-
- HY-W440719
-
|
|
|
Pegylated Lipids
|
|
Cholesterol-PEG2000-MAL is a PEG derivative and can be used to prepare liposome or nanoparticle due to its ability to self-assemble in water. The maleimide moiety is reactive with thiol molecule to form a covalent thioether bond.
|
-
- HY-W441004
-
|
|
|
Phospholipids
|
|
DSPE-Thiol is a phophalipid capped with thiol group. The thiol capped head can selectively react with maleimide. DSPE-Thiol can also be used for the preparation of phospholipid dimers .
|
-
- HY-166648A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG-Maleimide ammonium (MW 2000) is a functional lipid component and a thiol-reactive crosslinker. DSPE-PEG-Maleimide ammonium (MW 2000) undergoes Michael addition with the thiol groups of thiolated or cyclic RGD peptides to form stable thioether bonds and DSPE-PEG (2000)-RGD. DSPE-PEG-Maleimide ammonium (MW 2000) is applicable to research on drug delivery .
|
-
- HY-W441009A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-Maleimide ammonium has DSPE phospholipid and maleimide to prepare nanostructured lipid carrier. DSPE-PEG3400-Maleimide ammonium can be used in drug delivery research .
|
-
- HY-N15976
-
|
|
|
Pegylated Lipids
|
|
DMG-pSar25 Maleimide is a lipid conjugated to DMG, Maleimide and pSar25 polymer. DMG-pSar25 Maleimide can be used to prepare lipid nanoparticles for drug delivery.
|
-
- HY-W020780C
-
|
mPEG3400-Maleimide
|
|
Polymers
|
|
mPEG3400-Mal is a PEG derivative used for thiol pegylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
-
- HY-155901
-
|
Maleimide-NH-PEG2000-amine TFA
|
|
Polymers
|
|
Mal-NH-PEG2000-NH2TFA is a PEG derivative that may be used for thiol PEGylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
-
- HY-140739A
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG2000-Maleimide free acid is a phospholipid-PEG conjugate. DSPE-PEG2000-Maleimide free acid utilizes the amphiphilicity of DSPE to insert into the lipid bilayer of liposomes or nanoparticles. DSPE-PEG2000-Maleimide free acid covalently couples to the sulfhydryl (-SH) of ligands (such as antibodies, peptides, or proteins) via thiol-maleimide click chemistry, giving the particles targeting capabilities. DSPE-PEG2000-Maleimide free acid can be used in the researches of breast cancer, lymphoma, and inherited retinal degeneration .
|
-
- HY-W800787
-
|
|
|
Phospholipids
|
|
18:1 PE MCC is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two oleic acid tails and a maleimide group.
|
-
- HY-W440718C
-
|
|
|
Pegylated Lipids
|
|
Cholesterol-PEG10000-Mal is a PEG derivative composed of Cholesterol, PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups .
|
-
- HY-167036C
-
|
|
|
Pegylated Lipids
|
|
DMG-PEG5000-Mal is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG5000-Mal can be used for drug delivery .
|
-
- HY-W590555
-
|
|
|
Pegylated Lipids
|
|
Thiol-PEG2000-DMG is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc.
|
-
- HY-W800786
-
|
N-MCC-PE
|
|
Phospholipids
|
|
16:0 PE MCC is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two palmitic acid tails and a maleimide group.
|
-
- HY-W800789
-
|
|
|
Phospholipids
|
|
16:0 MPB PE is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two palmitic acid tails and a phenyl maleimide group.
|
-
- HY-W800788
-
|
|
|
Phospholipids
|
|
18:1 MPB PE is a maleimide-functionalized thiol-reactive lipid with a phosphoethanolamine linked to two oleic acid tails and a phenyl maleimide group.
|
-
- HY-167036A
-
|
|
|
Pegylated Lipids
|
|
DMG-PEG1000-Mal is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG1000-Mal can be used for drug delivery .
|
-
- HY-W020780A
-
|
mPEG350-Maleimide
|
|
Polymers
|
|
mPEG350-Mal is a PEG derivative used for thiol PEGylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
-
- HY-W020780B
-
|
mPEG750-Maleimide
|
|
Polymers
|
|
mPEG750-Mal is a PEG derivative used for thiol pegylation of protein molecules. Its maleimide group (-Mal) degrades in aqueous media and finds application in drug delivery studies.
|
-
- HY-W440897
-
|
|
|
Pegylated Lipids
|
|
DSPE-PEG3400-SH is a maleimide reactive PEG lipid. The amphiphilic polymer forms lipid bilayer in water and can be used to prepare liposomes for drug nanocarriers to deliver mRNA, DNA or siRNA.
|
-
- HY-W440722
-
|
|
|
Pegylated Lipids
|
|
Cholesterol-PEG1000-Thiol is a PEGylated lipid that forms micelles in water and can be used to prepare liposomes or nanoparticles as drug delivery systems. The thiol moiety reacts with maleimide to form a stable thioether bond .
|
-
- HY-W440724
-
|
|
|
Pegylated Lipids
|
|
Cholesterol-PEG3400-Thiol is an amphiphatic PEG derivative which forms micelles in water and can be used to prepare liposomes or nanoparticles for drug delivery system. The thiol moiety is reactive with maleimide to form a stable thioether bond.
|
-
- HY-182132
-
-
- HY-167036D
-
|
|
|
Pegylated Lipids
|
|
DMG-PEG10000-Mal is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG10000-Mal can be used for drug delivery .
|
-
- HY-167036B
-
|
|
|
Pegylated Lipids
|
|
DMG-PEG3400-Mal is a PEG derivative composed of N,N-Dimethylglycine (DMG), PEG units and Maleimide (HY-W007324). Maleimide forms a stable thioether bond with sulfhydryl (-SH) groups. DMG-PEG3400-Mal can be used for drug delivery .
|
-
- HY-147262
-
|
|
|
siRNAs
siRNA drugs
|
|
Etedesiran is a component of the AOC drug Delpacibart etedesiran (HY-177565), formed by the reaction of an siRNA that induces cleavage of mRNA encoding myotonic dystrophy protein kinase (MTPK or DMPK) with SMCC linker (HY-42360). Etedesiran carries a maleimide group at its terminus, which can react with cysteine or lysine and is used for the synthesis of AOC drugs. Etedesiran is applicable to research related to myotonic dystrophy type 1 .
|
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-171561G
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DOTAM-Maleimide triTFA (GMP) is DOTAM-Maleimide triTFA (HY-171561) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. DOTAM-Maleimide triTFA is a bifunctional chelator .
|
-
-
- HY-133540G
-
|
Maleimido-mono-amide-DOTA
|
ADC Linker
|
Inflammation/Immunology
Cancer
|
|
Maleimide-DOTA (Maleimido-mono-amide-DOTA) (GMP) is Maleimide-DOTA (HY-133540) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Maleimide-DOTA is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) .
|
-
-
- HY-13631EG
-
|
MC-GGFG-DXD
|
Drug-Linker Conjugates for ADC
|
Cancer
|
|
Deruxtecan (GMP) (MC-GGFG-DXD (GMP)) is Deruxtecan (HY-13631E) in GMP grade. GMP-grade small molecules can be used as auxiliary reagents in cell therapy. Deruxtecan is an ADC drug-linker conjugate composed of an DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing Trastuzumab deruxtecan (HY-138298A) and Patritumab deruxtecan (HY-P99813) .
|
-
-
- HY-42360G
-
|
|
ADC Linker
|
Inflammation/Immunology
Cancer
|
|
SMCC (GMP) is the GMP level of SMCC (HY-42360). GMP guidelines are used to produce SMCC (HY-42360) (GMP). GMP small molecules works appropriately as an auxiliary reagent for cell research manufacture. SMCC (GMP) is a protein crosslinker. SMCC (GMP) contains an amine-reactive N-hydroxysuccinimide ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. SMCC-conjugated antigen coupled spleen cells to induce antigen-specific immune responses.
|
-
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent:
![N-[4-(2-Benzimidazolyl)phenyl]maleimide](http://file.medchemexpress.com/product_pic/hy-w278706.gif)
![Mal((3S,3aR,6S,6aR)-Hexahydrofuro[3,2-b]furan-3,6-diamine-PEG12)-β-Glu-PAB](http://file.medchemexpress.com/product_pic/hy-173635.gif)
![TGA-Val-Ala-NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT](http://file.medchemexpress.com/product_pic/hy-171946.gif)
