9 Results for "

matrix metalloproteinase enzymes

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "matrix metalloproteinase enzymes" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-100211
CAS No.: 187034-31-7
Purity:  97.41%
Synonyms: TNF Protease Inhibitor 2
Target:  

MMP SARS-CoV

Research Areas:  

Cancer

TAPI-2 (TNF Protease Inhibitor 2) is a broad-spectrum inhibitor of matrix metalloprotease (MMP), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM), with an IC50 of 20 μM for MMP . TAPI-2 blocks the entry of infectious SARS-CoV .
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Cat. No.: HY-19518
CAS No.: 860005-21-6
Synonyms: NCX116; LBN
Research Areas:  

Neurological Disease

Latanoprostene bunod (NCX116; LBN) is a nitric oxide-releasing prostaglandin F2α analog. Latanoprostene bunod is a prodrug that, upon instillation into the eye, is hydrolyzed by corneal esterases into two active metabolites: Latanoprost (HY-B0577) and NO. Latanoprost activates the prostaglandin FP receptor to increase the outflow of aqueous humor through the uveoscleral pathway. NO increases aqueous humor drainage through the trabecular meshwork pathway, achieving synergistic enhancement targeting the dual pathways of aqueous humor outflow. Latanoprostene bunod can be used in research related to open-angle glaucoma and ocular hypertension .
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Cat. No.: HY-W041193
CAS No.: 496-64-0
3-Hydroxy-2-pyrone (Compound 12d) is a metalloenzyme inhibitor. 3-Hydroxy-2-pyrone shows an inhibition rate of approximately 50% for matrix metalloproteinases (MMP) and the inhibition rate for non-heme iron enzyme 5-lipoxygenase (5-LOX) was over 70% at 1 mM. 3-Hydroxy-2-pyrone also has certain inhibitory activity against copper-dependent enzyme tyrosinase. 3-Hydroxy-2-pyrone can be used for the research of cancer, infection and inflammation .
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Cat. No.: HY-136885
CAS No.: 143457-40-3
Target:  

MMP

Research Areas:  

Infection

(S,S)-TAPI-0 is a matrix metalloproteinase (MMP) inhibitor that inhibits the growth of Chlamydia trachomatis by inhibiting PDF enzyme activity. (S,S)-TAPI-0 can be used to study Chlamydia infection .
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Cat. No.: HY-115351
CAS No.: 212609-68-2
Target:  

TNF Receptor MMP

Research Areas:  

Inflammation/Immunology

GW-3333 is a potent and orally active TNF-alpha-converting enzyme (TACE) and matrix metalloproteinases (MMP) inhibitor. GW-3333 inhibits tumor necrosis factor-alpha (TNF-alpha) production. GW-3333 can be used in research of arthritis .
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Cat. No.: HY-174750
Target:  

mRNA

Research Areas:  

Inflammation/Immunology

Human CCL7 mRNA encodes the human C-C motif chemokine ligand 7 (CCL7) protein, a member of the CC subfamily which is characterized by two adjacent cysteine residues. CCL7 is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix.
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Cat. No.: HY-100211A
CAS No.: 689284-12-6
Synonyms: (R)-TNF Protease Inhibitor 2
Target:  

SARS-CoV MMP

Research Areas:  

Cancer

(R)-TAPI-2 is the isomer of TAPI-2 (HY-100211A). TAPI-2 (TNF Protease Inhibitor 2) is a broad-spectrum inhibitor of matrix metalloprotease (MMP), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM), with an IC50 of 20 μM for MMP . TAPI-2 blocks the entry of infectious SARS-CoV .
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Cat. No.: HY-111172
CAS No.: 906366-79-8
Target:  

MMP NF-κB

Research Areas:  

Cancer

Inotilone is an inhibitor of matrix metalloproteinase MMP-2 and MMP-9, to against metastatic in lung cancer cells. Inotilone enhances the activity of the antioxidant enzymes to support its anti-metastatic activity. Inotilone also inhibits IκBα phosphorylation and NFκB p65 nuclear translocation, involving in FAK, PI3K/AKT, MAPKs and NFκB pathways .
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Cat. No.: HY-100211R
CAS No.: 187034-31-7
Synonyms: TNF Protease Inhibitor 2 (Standard)
Research Areas:  

Cancer

TAPI-2 (Standard) is the analytical standard of TAPI-2 (HY-100211). This product is intended for research and analytical applications. TAPI-2 (TNF Protease Inhibitor 2) is a broad-spectrum inhibitor of matrix metalloprotease (MMP), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM), with an IC50 of 20 μM for MMP . TAPI-2 blocks the entry of infectious SARS-CoV .
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