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Pathways Recommended: Metabolic Enzyme/Protease
Results for "

matrix metalloproteinase enzymes

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Natural
Products

1

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-100211
    TAPI-2
    5 Publications Verification

    TNF Protease Inhibitor 2

    		 MMP SARS-CoV Cancer
    TAPI-2 (TNF Protease Inhibitor 2) is a broad-spectrum inhibitor of matrix metalloprotease (MMP), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM), with an IC50 of 20 μM for MMP . TAPI-2 blocks the entry of infectious SARS-CoV .
    TAPI-2
  • HY-19518
    Latanoprostene bunod

    NCX116; LBN

    		 Prostaglandin Receptor Neurological Disease
    Latanoprostene bunod (NCX116; LBN) is a nitric oxide-releasing prostaglandin F2α analog. Latanoprostene bunod is a prodrug that, upon instillation into the eye, is hydrolyzed by corneal esterases into two active metabolites: Latanoprost (HY-B0577) and NO. Latanoprost activates the prostaglandin FP receptor to increase the outflow of aqueous humor through the uveoscleral pathway. NO increases aqueous humor drainage through the trabecular meshwork pathway, achieving synergistic enhancement targeting the dual pathways of aqueous humor outflow. Latanoprostene bunod can be used in research related to open-angle glaucoma and ocular hypertension .
    Latanoprostene bunod
  • HY-W041193
    3-Hydroxy-2-pyrone

    		MMP Lipoxygenase Tyrosinase Infection Inflammation/Immunology Cancer
    3-Hydroxy-2-pyrone (Compound 12d) is a metalloenzyme inhibitor. 3-Hydroxy-2-pyrone shows an inhibition rate of approximately 50% for matrix metalloproteinases (MMP) and the inhibition rate for non-heme iron enzyme 5-lipoxygenase (5-LOX) was over 70% at 1 mM. 3-Hydroxy-2-pyrone also has certain inhibitory activity against copper-dependent enzyme tyrosinase. 3-Hydroxy-2-pyrone can be used for the research of cancer, infection and inflammation .
    3-Hydroxy-2-pyrone
  • HY-136885
    (S,S)-TAPI-0

    		MMP Infection
    (S,S)-TAPI-0 is a matrix metalloproteinase (MMP) inhibitor that inhibits the growth of Chlamydia trachomatis by inhibiting PDF enzyme activity. (S,S)-TAPI-0 can be used to study Chlamydia infection .
    (S,S)-TAPI-0
  • HY-115351
    GW-3333

    		TNF Receptor MMP Inflammation/Immunology
    GW-3333 is a potent and orally active TNF-alpha-converting enzyme (TACE) and matrix metalloproteinases (MMP) inhibitor. GW-3333 inhibits tumor necrosis factor-alpha (TNF-alpha) production. GW-3333 can be used in research of arthritis .
    GW-3333
  • HY-174750
    Human CCL7 mRNA

    		mRNA Inflammation/Immunology
    Human CCL7 mRNA encodes the human C-C motif chemokine ligand 7 (CCL7) protein, a member of the CC subfamily which is characterized by two adjacent cysteine residues. CCL7 is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix.
    Human CCL7 mRNA
  • HY-100211A
    (R)-TAPI-2

    (R)-TNF Protease Inhibitor 2

    		 SARS-CoV MMP Cancer
    (R)-TAPI-2 is the isomer of TAPI-2 (HY-100211A). TAPI-2 (TNF Protease Inhibitor 2) is a broad-spectrum inhibitor of matrix metalloprotease (MMP), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM), with an IC50 of 20 μM for MMP . TAPI-2 blocks the entry of infectious SARS-CoV .
    (R)-TAPI-2
  • HY-111172
    Inotilone

    		MMP NF-κB Cancer
    Inotilone is an inhibitor of matrix metalloproteinase MMP-2 and MMP-9, to against metastatic in lung cancer cells. Inotilone enhances the activity of the antioxidant enzymes to support its anti-metastatic activity. Inotilone also inhibits IκBα phosphorylation and NFκB p65 nuclear translocation, involving in FAK, PI3K/AKT, MAPKs and NFκB pathways .
    Inotilone
  • HY-100211R
    TAPI-2 (Standard)

    TNF Protease Inhibitor 2 (Standard)

    		 MMP Reference Standards SARS-CoV Cancer
    TAPI-2 (Standard) is the analytical standard of TAPI-2 (HY-100211). This product is intended for research and analytical applications. TAPI-2 (TNF Protease Inhibitor 2) is a broad-spectrum inhibitor of matrix metalloprotease (MMP), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM), with an IC50 of 20 μM for MMP . TAPI-2 blocks the entry of infectious SARS-CoV .
    TAPI-2 (Standard)

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