906366-79-8
906366-79-8
Chemical Structure
Inotilone
- CAS No.: 906366-79-8
- Formula:C12H10O4
- Molecular Weight:218.21
IUPAC Name: (Z)-2-(3,4-dihydroxybenzylidene)-5-methylfuran-3(2H)-one
InChIKey: NLZQGBCUKNUDED-SDQBBNPISA-N
SMILES: O=C1/C(OC(C)=C1)=C/C2=CC=C(O)C(O)=C2
Biological Activity: Inotilone is an inhibitor of matrix metalloproteinase MMP-2 and MMP-9, to against metastatic in lung cancer cells. Inotilone enhances the activity of the antioxidant enzymes to support its anti-metastatic activity. Inotilone also inhibits IκBα phosphorylation and NFκB p65 nuclear translocation, involving in FAK, PI3K/AKT, MAPKs and NFκB pathways[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Inotilone | 95.26% | Inotilone is an inhibitor of matrix metalloproteinase MMP-2 and MMP-9, to against metastatic in lung cancer cells. Inotilone enhances the activity of the antioxidant enzymes to support its anti-metastatic activity. Inotilone also inhibits IκBα phosphorylation and NFκB p65 nuclear translocation, involving in FAK, PI3K/AKT, MAPKs and NFκB pathways. | ||||||||||||||||||||
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