24 Results for "

melanin biosynthesis

" in MedChemExpress (MCE) Product Catalog:
Products (24)

24 Results for "melanin biosynthesis" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-B0848
CAS No.: 41814-78-2
Tricyclazole is a pentaketone melanin biosynthesis inhibitor and a unique fungicide for controlling rice blast. Tricyclazole alters the structure and function of fungal cell walls, reduces fungal pathogenicity and penetration, and causes dose-dependent liver damage in animals .
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Cat. No.: HY-126052
CAS No.: 86361-55-9
Purity:  99.86%
Gnetol is a phenolic compound isolated from the root of Gnetum montanum . Gnetol potently inhibits COX-1 (IC50 of 0.78 μM) and HDAC. Gnetol is a potent tyrosinase inhibitor with an IC50 of 4.5 μM for murine tyrosinase and suppresses melanin biosynthesis. Gnetol has antioxidant, antiproliferative, anticancer and hepatoprotective activity. Gnetol also possesses concentration-dependent α-Amylase, α-glucosidase, and adipogenesis activities .
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Cat. No.: HY-N6243
CAS No.: 475-00-3
Veratrosine is a Trihydroxynapthalene reductase (THR) inhibitor and fungal plant pathogen inhibitor. Veratrosine interacts with THR, an enzyme in the DHN melanin biosynthesis pathway of Curvularia lunata. Veratrosine can be used for the research of leaf blight of rice, brown spot of rice, and blast disease of foxtail millet .
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Cat. No.: HY-N4265
CAS No.: 156009-80-2
Vinaginsenoside R4, isolated from the leaves of hydroponic Panax ginseng. It has an inhibitory effect on melanin biosynthesis without any cytotoxic effects on the melan-a cells, and enhances the depigmentation on the zebrafish .
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Cat. No.: HY-N9521
CAS No.: 110081-91-9
3-O-β-D-Glucopyranosyl(1→2)-[a-Lrhamnopyranosyl(1→3)]-β-D-glucopyranosyl 28-O-β-D-glucuronopyranoside, a saponin, is isolated from Polaskia chichipe Backbg. 3-O-β-D-Glucopyranosyl(1→2)-[a-Lrhamnopyranosyl(1→3)]-β-D-glucopyranosyl 28-O-β-D-glucuronopyranoside shows ability to inhibit melanin biosynthesis by B16 melanoma cell with inhibitory activity 84.2% at 100μM[1].
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Cat. No.: HY-W775186
CAS No.: 911499-62-2
Target:  

Fungal

Research Areas:  

Infection

Tolprocarb is an oomyces fungicide, which has a strong inhibitory effect on rice blast fungus Magnaporthe grisea by inhibiting polyketide synthase in melanin synthesis pathway .
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Cat. No.: HY-163326
Target:  

Tyrosinase

Research Areas:  

Cancer

Tyrosinase-IN-25 (compound 1l) is an inhibitor of tyrosinase and melanin biosynthesis in human melanoma cells .
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Cat. No.: HY-W050154R
CAS No.: 501-30-4
Kojic acid (Standard) is the analytical standard of Kojic acid. This product is intended for research and analytical applications. Kojic acid is a substance produced by Aspergillus oryzae, with various biological activities including antitumor, insecticidal, antibacterial, antioxidant, and radioprotective effects. Kojic acid exhibits tyrosinase inhibition activity by capturing copper ions that bind to the active site of tyrosinase, preventing its activation. Tyrosinase is a key enzyme in the biosynthesis of melanin, so kojic acid can block melanin production. Additionally, kojic acid shows potential inhibition of NF-κB activity in human keratinocytes, which may also be related to the anti-melanogenic effect induced by kojic acid. Kojic acid is effective when administered orally and can also be absorbed transdermally. Nano-carrier systems prepared with kojic acid demonstrate effective delivery of anticancer drugs. Kojic acid holds promise for research in cancer, infectious diseases, and skin whitening among other fields .
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Cat. No.: HY-161241
CAS No.: 3030420-71-1
Target:  

Tyrosinase

Research Areas:  

Cancer

Tyrosinase-IN-23 (Compd 11m) is a tyrosinase inhibitor with an IC50 of 55.39±4.93 µM. Tyrosinase-IN-23 can be used for research of melanin biosynthesis .
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Cat. No.: HY-N14240
CAS No.: 670274-36-9
Melanocin A is a Melanin biosynthesis inhibitor. Melanocin A inhibits the biosynthesis of melanin and tyrosinase (IC50 is 9.0 nM, MIC is 0.9 μM). Melanocin A also has antioxidant effect .
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Cat. No.: HY-W725641
Tricyclazole-d3 is the deuterium labeled Tricyclazole. Tricyclazole is a pentaketide-derived melanin biosynthesis inhibitor.
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Cat. No.: HY-N13922
CAS No.: 208183-19-1
Scytalol A selectively inhibits biosynthesis of dihydroxynaphthalene melanin in Lachnellula sp. A32-89, but does not inhibit the growth of the strain .
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Cat. No.: HY-N14245
CAS No.: 178275-98-4
Melanoxazal is a Melanin biosynthesis inhibitor. Melanoxazal can inhibit melanin formation in the silkworm larva hemolymph (IC50 is 30.1 μg/mL), and also has stronger inhibitory effect against mushroom tyrosinase (IC50 is 4.2 μg/mL), but it has no antimicrobial effect .
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Cat. No.: HY-N1098R
CAS No.: 25739-41-7
Colchiceine (Standard) is the analytical standard of Colchiceine. This product is intended for research and analytical applications. Colchiceine is one of several metabolites of the anti-gout medication Colchicine (HY-16569). Colchicine is a tubulin inhibitor and a microtubule disrupting agent, and may protect rats from developing liver injury and fibrosis .
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Cat. No.: HY-N12431
CAS No.: 110269-50-6
Machilin A is a lignan isolated from the methanolic extract of Phoebe bark. Machilin A inhibits melanin biosynthesis in B-16 mouse melanoma cells with an IC50 of 39.9 μM.
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Cat. No.: HY-B0848R
CAS No.: 41814-78-2
Research Areas:  

Infection

Tricyclazole (Standard) is the analytical standard of Tricyclazole. This product is intended for research and analytical applications. Tricyclazole is a pentaketide-derived melanin biosynthesis inhibitor and a unique fungicide for control of Pyricularia oryzae on rice .
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Cat. No.: HY-111898
CAS No.: 93380-12-2
Purity:  99.38%
Category:  

Plants

Epirosmanol is a nature diterpene lactone from S. officinalis. Epirosmanol shows anti-cancer activity and inhibits melanin biosynthesis against melanoma cells. Epirosmanol also exhibits DPPH radical scavenging activity .
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Cat. No.: HY-143449
CAS No.: 180864-33-9
Purity:  99.71%
Target:  

Tyrosinase

Research Areas:  

Others

Tyrosinase-IN-2 (compound 67) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-2 has the potential for the research of skin whitening agents and food preservatives .
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Cat. No.: HY-143448
CAS No.: 1164200-43-4
Target:  

Tyrosinase

Research Areas:  

Others

Tyrosinase-IN-1 (compound 90) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-1 has the potential for the research of skin whitening agents and food preservatives .
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Cat. No.: HY-143450
CAS No.: 2409081-40-7
Target:  

Tyrosinase

Research Areas:  

Others

Tyrosinase-IN-3 (compound 54) is a potent inhibitor of tyrosinase. Tyrosinase is a copper-containing metalloenzyme that is responsible for the rate-limiting catalytic step in the melanin biosynthesis and enzymatic browning. Tyrosinase-IN-3 has the potential for the research of skin whitening agents and food preservatives .
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