6 Results for "

nonsense-mediated mRNA decay

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "nonsense-mediated mRNA decay" in MCE Product Catalog:

  • Targets Recommended:
Cat. No.: HY-P811808
Synonyms: nonsense-mediated mRNA decay factor SMG5; EST1B; KIAA1089

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, FC

Reactivity:  

Human

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Cat. No.: HY-P811962
Synonyms: C19orf61, SMG9, nonsense-mediated mRNA decay factor SMG9

Host:  

Mouse

Application:  

WB, FC, ICC/IF

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P811808A
Synonyms: nonsense-mediated mRNA decay factor SMG5; EST1B; KIAA1089

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, FC

Reactivity:  

Human

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Cat. No.: HY-P811962A
Synonyms: C19orf61, SMG9, nonsense-mediated mRNA decay factor SMG9

Host:  

Mouse

Application:  

WB, FC, ICC/IF

Reactivity:  

Human, Mouse, Rat

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MDM4-targeting ASO sodium
0 Images
MDM4-targeting ASO (sodium)
Cat. No.: HY-158830
MDM4-targeting ASO sodium is a 25mer antisense oligonucleotide targeting MDM4. MDM4-targeting ASO sodium induced exon 6 skipping, leading to nonsense-mediated decay of the mRNA transcript that excludes exon-6. In multiple human melanoma cell lines and in melanoma patient-derived xenograft (PDX) mouse models, MDM4-targeting ASO-mediated skipping of exon 6 decreased MDM4 abundance, inhibited melanoma growth, and enhanced sensitivity to MAPK-targeting therapeutics.
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Cat. No.: HY-P703303
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SMG6; Smg-6 Homolog, nonsense mediated mRNA decay Factor (C. Elegans); Prev. C17orf31; Smg-6 Homolog, nonsense mediated mRNA decay Factor; EST1A; SMG6, nonsense mediated mRNA decay Factor; KIAA0732; Chromosome 17 Open Reading Frame 31; SMG-6; EST1 Telomer
Species:  
Human
Source:  
E. coli
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