Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
palmitoyl protein thioesterase
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "palmitoyl protein thioesterase" in MCE Product Catalog:
6
3
Research Areas:
Ezurpimtrostat (GNS561) is an orally active PPT1 inhibitor, autophagy inhibitor, immunomodulator, anti-inflammatory agent, and anticancer agent. Ezurpimtrostat inhibits PPT1, dysregulates lysosomal function, redistributes mTOR, and induces apoptosis. Ezurpimtrostat reduces IFN‑α, CRP, immune complex deposition, and SARS‑CoV‑2 viral load. Ezurpimtrostat can be used for the study of systemic lupus erythematosus, SARS‑CoV‑2, hepatocellular carcinoma, fibrosis, and related disorders .
1
1 Cited Publications
Cat. No.: HY-P71230
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: PPT1; INCL; Prev. PPT; Ceroid-Lipofuscinosis, Neuronal 1, Infantile; CLN1; PPT-1; palmitoyl-protein Hydrolase 1; palmitoyl-protein thioesterase 1; Ceroid-palmitoyl-palmitoyl-protein thioesterase 1
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P700622
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PPT1; INCL; Prev. PPT; Ceroid-Lipofuscinosis, Neuronal 1, Infantile; CLN1; PPT-1; palmitoyl-protein Hydrolase 1; palmitoyl-protein thioesterase 1; Ceroid-palmitoyl-palmitoyl-protein thioesterase 1
Species:
Mouse
Source:
HEK293
Cat. No.: HY-145519
CAS No.: 229644-17-1
Target:
Research Areas:
Mu-6S-Palm-β-Glc is a fluorogenic substrate for palmitoyl-protein thioesterase (PPT). Mu-6S-Palm-β-Glc can be used for the research of neuronal ceroid lipofuscin disease in infants .
Target:
Research Areas:
ABC44 is a potent serine hydrolase inhibitor with IC50s of 0.1 μM and 6.5 μM for palmitoyl protein thioesterase 1 (PPT1) in situ and in vitro, respectively. ABC44 can be used for researching infantile neuronal ceroid lipofuscinosis .
Cat. No.: HY-118621
CAS No.: 126062-19-9
JCP174 is an inhibitor of palmitoyl protein thioesterase-1 (TgPPT1), a depalmitoylase in the parasite T. gondii . JCP174 is also an inhibitor of porcine pancreatic elastase and human leukocyte elastase .
Cat. No.: HY-P7452
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ACOT13; Hotdog-Fold thioesterase Superfamily Member 2; Prev. THEM2; palmitoyl-CoA Hydrolase; thioesterase Superfamily Member 2; Hypothalamus protein HT012; HT012; PNAS-27; Acyl-CoA thioesterase 13; Acyl-Coenzyme A thioesterase 13
Species:
Human
Source:
HEK293
Cat. No.: HY-P70221
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LYPLA2; APT2; Lysophospholipase 2; LysoPLA II; APT-2; LPL-II; Acyl-protein thioesterase 2; Testicular Tissue protein Li 3; palmitoyl-protein Hydrolase; DJ886K2.4; Lysophospholipase II
Species:
Human
Source:
E. coli
Cat. No.: HY-P7539
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: LYPLA1; palmitoyl-protein Hydrolase; Lysophospholipase 1; APT1; Acyl-protein thioesterase 1; LysoPLA I; Lysophospholipase I; LPL-I; APT-1; HAPT1; LPL1; Lysophospholipid-Specific Lysophospholipase
Species:
Human
Source:
E. coli
Cat. No.: HY-P706190
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Bis(monoacylglycero)phosphate synthase CLN5; BMP synthase CLN5; Ceroid-lipofuscinosis neuronal protein 5 (protein CLN5); palmitoyl protein thioesterase CLN5; S-depalmitoylase CLN5; Bis(monoacylglycero)phosphate synthase CLN5, secreted form; CLN5; BMPS
Species:
Human
Source:
E. coli
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
