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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
28 Results for "
parathyroid cell
" in MedChemExpress (MCE) Product Catalog:
Products (28)
28 Results for "parathyroid cell" in MCE Product Catalog:
4
Category:
Seeds of Cassia tora Linn. Plants Quinones other families Leguminosae Anthraquinones Phenols Polyphenols Disease Research Fields Cancer
Target:
3
Target:
Research Areas:
Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .
2
1
Category:
Human Gut Microbiota Metabolites Natural Products Other Diseases Endogenous metabolite Disease Research Fields
Target:
1
1 Cited Publications
Cat. No.: HY-P702687
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK6; cell Division Protein Kinase 6; Cyclin Dependent Kinase 6; Cyclin-Dependent Kinase 6; PLSTIRE; MCPH12; Serine/Threonine-Protein Kinase PLSTIRE; CDKN6; CCND1; B-cell CLL/Lymphoma 1; Prev. PRAD1; PRAD1 Oncogene; Prev. BCL1; parathyroid Adenomatosis 1
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Cat. No.: HY-P702682
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CDK4; Cyclin-Dependent Kinase 4; Cyclin Dependent Kinase 4; Cyclin-Dependent Kinase; PSK-J3; MCPH31; cell Division Protein Kinase 4; CMM3; CCND1; B-cell CLL/Lymphoma 1; Prev. PRAD1; PRAD1 Oncogene; Prev. BCL1; parathyroid Adenomatosis 1; Prev. D11S287E; C
Species:
Human
Source:
Sf9 insect cells
Synonyms: SK-1403; AJT240; PLS240
Target:
Research Areas:
Upacicalcet sodium is a non-peptide calcimimetic that acts as a CaSR agonist (EC50 = 10.8 nM). Upacicalcet sodium reduces serum intact parathyroid hormone (iPTH) and serum Ca 2+ levels, reducing hypocalcemia and gastrointestinal complications. Upacicalcet sodium sodium improves vascular calcification and bone disorders in the Adenine (HY-B0152)-induced secondary hyperparathyroidism (SHPT) rat model. Upacicalcet sodium sodium inhibits cortical pore formation and reduces bone fibrosis in rats with chronic kidney disease (CKD). Upacicalcet sodium is useful for studying SHPT .
Synonyms: Litoralon
Target:
Research Areas:
Glutaurine containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine, as a hormone, is isolated from parathyroid gland oxyphil cells. Glutaurine can be used for the research of antiepileptic and anti-amnesia .
Cat. No.: HY-16498
CAS No.: 848084-83-3
Synonyms: PCK-3145
Research Areas:
Cat. No.: HY-17613R
CAS No.: 870964-67-3
Synonyms: KHK7580 (Standard)
Target:
Research Areas:
Evocalcet (Standard) is the analytical standard of Evocalcet. This product is intended for research and analytical applications. Evocalcet (KHK7580) is an orally active calcium sensing receptor (CaSR) agonist. Evocalcet inhibits the secretion of parathyroid hormone (PTH) from parathyroid gland cells. Evocalcet can be used for the research of hyperparathyroidism .
Cat. No.: HY-B2097
CAS No.: 138330-18-4
Synonyms: YM 175; Bisphonal
Target:
Research Areas:
Incadronate disodium (YM 175) is a bisphosphonate with strong inhibitory activity on bone resorption. Incadronate disodium indirectly stimulates renal 25-hydroxyvitamin D-1-hydroxylase by increasing circulating parathyroid hormone. Incadronate disodium, a cholesterol-lowering agent, is a potent inhibitor of rat liver microsomal squalene synthase (Ki=57 nM). Incadronate disodium inhibits sterol biosynthesis in mouse macrophage J774 cells (IC50=64 μM). Incadronate disodium has the potential for malignant tumors research .
Cat. No.: HY-P4856
CAS No.: 120298-73-9
Research Areas:
Cat. No.: HY-179475
CAS No.: 1262781-19-0
Target:
Research Areas:
Cat. No.: HY-131206
CAS No.: 2460353-87-9
Target:
Research Areas:
DS37571084 is an orally active competitive antagonist of parathyroid hormone receptor 1 (PTH1R) with an IC50 value of 0.17 μM. DS37571084 is applicable to the research of bone diseases and calcium metabolism disorders associated with primary hyperparathyroidism .
Cat. No.: HY-P2510
Target:
Research Areas:
Cat. No.: HY-109106
CAS No.: 1333218-50-0
Synonyms: SK-1403 free acid; AJT240 free acid; PLS240 free acid
Target:
Research Areas:
Upacicalcet is a non-peptide calcimimetic that acts as a CaSR agonist (EC50 = 10.8 nM). Upacicalcet reduces serum intact parathyroid hormone (iPTH) and serum Ca2+ levels, reducing hypocalcemia and gastrointestinal complications. Upacicalcet improves vascular calcification and bone disorders in the Adenine (HY-B0152)-induced secondary hyperparathyroidism (SHPT) rat model. Upacicalcet inhibits cortical pore formation and reduces bone fibrosis in rats with chronic kidney disease (CKD). Upacicalcet is useful for studying SHPT .
Cat. No.: HY-106608A
Synonyms: Litoralon TFA
Target:
Research Areas:
Glutaurine (Litoralon) TFA containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine (Litoralon) TFA, as a hormone, is isolated from parathyroid gland oxyphil cells. Glutaurine (Litoralon) TFA can be used for the research of antiepileptic and anti-amnesia .
Cat. No.: HY-17613S
Synonyms: KHK7580-d4
Cat. No.: HY-112171R
CAS No.: 5875-41-2
Synonyms: γ-Glu-Ala (Standard)
Category:
Seeds of Cassia tora Linn. Quinones other families Leguminosae Anthraquinones Phenols Polyphenols Plants
Target:
- 1
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
