5875-41-2
5875-41-2
Chemical Structure
γ-L-Glutamyl-L-alanine
Synonym(s): γ-Glu-Ala
- CAS No.: 5875-41-2
- Formula:C8H14N2O5
- Molecular Weight:218.21
IUPAC Name: N5-((S)-1-carboxyethyl)-L-glutamine
InChIKey: WQXXXVRAFAKQJM-WHFBIAKZSA-N
SMILES: OC([C@@H](N)CCC(N[C@@H](C)C(O)=O)=O)=O
Biological Activity: γ-L-Glutamyl-L-alanine (γ-Glu-Ala), composed of gamma-glutamate and alanine, is a proteolytic breakdown product of larger proteins. γ-L-Glutamyl-L-alanine is a natural substrate of the γ-Glutamylcyclotransferase. γ-L-Glutamyl-L-alanine is a positive modulator of calcium-sensing receptor (CaR) function[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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γ-L-Glutamyl-L-alanine | 98.0% | γ-L-Glutamyl-L-alanine (γ-Glu-Ala), composed of gamma-glutamate and alanine, is a proteolytic breakdown product of larger proteins. γ-L-Glutamyl-L-alanine is a natural substrate of the γ-Glutamylcyclotransferase. γ-L-Glutamyl-L-alanine is a positive modulator of calcium-sensing receptor (CaR) function. | ||||||||||||||||||||
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γ-L-Glutamyl-L-alanine (Standard) | 99.29% | γ-L-Glutamyl-L-alanine (Standard) is the analytical standard of γ-L-Glutamyl-L-alanine. This product is intended for research and analytical applications. γ-L-Glutamyl-L-alanine, composed of gamma-glutamate and alanine, is a proteolytic breakdown product of larger proteins. γ-L-Glutamyl-L-alanine is a natural substrate of the γ-Glutamylcyclotransferase. γ-L-Glutamyl-L-alanine is a positive modulator of calcium-sensing receptor (CaR) function. | ||||||||||||||||||||
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gamma-DGG | 99.16% | gamma-DGG is a competitive AMPA receptor blocker. | ||||||||||||||||||||
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H-Ala-Glu-OH | 98.0% | Ala-Glu-OH is an agent of the dipeptide. | ||||||||||||||||||||
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N-Succinyl-D-alanine | N-Succinyl-D-alanine, a natural cell wall precursor analogue, is a peptide ligand of antibiotic Ristocetin A. | |||||||||||||||||||||
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γ-Glu-Gly | 98.0% | γ-Glu-Gly, a γ-glutamyl dipeptide, is a human lipid metabolite.γ-Glu-Gly has a similar structure to GABA (γ-aminobutyric acid) and can act as an antagonist of excitatory amino acids. | ||||||||||||||||||||
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β-Aspartylalanine | 98.99% | β-Aspartylalanine is a substrate for β-aspartyl peptidase and used to measure β-aspartyl peptidase activity in fecal supernatants. | ||||||||||||||||||||
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H-Asp-Ala-OH | H-Asp-Ala-OH is adipeptide. | |||||||||||||||||||||
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Ala-d-Gln | Ala-d-Gln is adipeptide. | |||||||||||||||||||||
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d-Ala-Gln | d-Ala-Gln is adipeptide. | |||||||||||||||||||||
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L-Alanyl-L-glutamine | 99.84% | L-Alanyl-L-glutamine, a glutamine dipeptide, is benefit for the antioxidant system, attenuating inflammation, and may modulate the heat shock protein (HSP) response in catabolic situations. | ||||||||||||||||||||
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Glycyl-L-glutamic acid | 99.82% | Glycyl-L-glutamic acid is a neurotrophic factor (NF) in vivo, and exerts function of maintenance of AChE content and activity. Glycyl-L-glutamic acid doesn’t act directly on AChE synthesis, and may prevent preganglionic neuronal degeneration. | ||||||||||||||||||||
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References
- [1]. Ovchinnikova OG, et al. Structure of a polysaccharide from Providencia rustigianii O11 containing a novel amide of 2-acetamido-2-deoxygalacturonic acid with L-glutamyl-L-alanine. Carbohydr Res. 2012 Feb 15;349:95-102. [Content Brief]
- [2]. York MJ, et al. gamma-Glutamylcyclotransferase: inhibition by D-beta-aminoglutaryl-L-alanine and analysis of the solvent kinetic isotope effect. Eur J Biochem. 1989 Sep 1;184(1):97-101. [Content Brief]
- [3]. Broadhead GK, et al. Allosteric modulation of the calcium-sensing receptor by gamma-glutamyl peptides: inhibition of PTH secretion, suppression of intracellular cAMP levels, and a common mechanism of action with L-amino acids. J Biol Chem. 2011 Mar 18;286(11):8786-97.
- [4]. Tatsuo Yamamoto, et al. Further Characterization of Glutaminase Isozymes from Pseudomonas aeruginosa.
