1. Vitamin D Related/Nuclear Receptor
  2. Thyroid Hormone Receptor
  3. Glutaurine

Glutaurine containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine, as a hormone, is isolated from parathyroid gland oxyphil cells. Glutaurine can be used for the research of antiepileptic and anti-amnesia.

For research use only. We do not sell to patients.

Glutaurine Chemical Structure

Glutaurine Chemical Structure

CAS No. : 56488-60-9

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Description

Glutaurine containing glutamine and taurine residues is an orally active hormone of the parathyroid. Glutaurine, as a hormone, is isolated from parathyroid gland oxyphil cells. Glutaurine can be used for the research of antiepileptic and anti-amnesia[1][2][3][4].

In Vivo

Glutaurine (1, 10, 20 or 50 μg/rat; p.o.) significantly restores the latency of entry in both the 24 and 48 hours tests at the dose of 50 μg/rat[2].
Glutaurine (100~3000 ug/kg; i.p.) significantly reduces T3 blood levels in a dose-dependent manner, but does not significantly raise T4 blood levels[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: CFY male rats (170~250g)[2]
Dosage: 1, 10, 20 or 50 μg/rat
Administration: P.o.
Result: Significantly restored the latency of entry in both the 24 and 48 h tests at the dose of 50 μg/rat.
Animal Model: Fischer 344 rats[3]
Dosage: 100~3000 ug/kg
Administration: I.p.
Result: Significantly reduced T3 blood levels in a dose-dependent manner, but did not significantly raise T4 blood levels.
Molecular Weight

254.26

Formula

C7H14N2O6S

CAS No.
SMILES

OC([C@@H](N)CCC(NCCS(=O)(O)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (491.62 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9330 mL 19.6649 mL 39.3298 mL
5 mM 0.7866 mL 3.9330 mL 7.8660 mL
View the Complete Stock Solution Preparation Table

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.9330 mL 19.6649 mL 39.3298 mL 98.3246 mL
5 mM 0.7866 mL 3.9330 mL 7.8660 mL 19.6649 mL
10 mM 0.3933 mL 1.9665 mL 3.9330 mL 9.8325 mL
15 mM 0.2622 mL 1.3110 mL 2.6220 mL 6.5550 mL
20 mM 0.1966 mL 0.9832 mL 1.9665 mL 4.9162 mL
25 mM 0.1573 mL 0.7866 mL 1.5732 mL 3.9330 mL
30 mM 0.1311 mL 0.6555 mL 1.3110 mL 3.2775 mL
40 mM 0.0983 mL 0.4916 mL 0.9832 mL 2.4581 mL
50 mM 0.0787 mL 0.3933 mL 0.7866 mL 1.9665 mL
60 mM 0.0655 mL 0.3277 mL 0.6555 mL 1.6387 mL
80 mM 0.0492 mL 0.2458 mL 0.4916 mL 1.2291 mL
100 mM 0.0393 mL 0.1966 mL 0.3933 mL 0.9832 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Glutaurine
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HY-106608
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