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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
33 Results for "
phosphatidylglycerol
" in MedChemExpress (MCE) Product Catalog:
Products (33)
33 Results for "phosphatidylglycerol" in MCE Product Catalog:
1
Synonyms: DSPG sodium
1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium) is the component of liposomes for drug delivery .
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(Rac)-1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium) is an anionic phospholipid, can be studied for drug delivery and the synthesis of liposomes. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol-containing liposomes can induce Tregs that are specific for the liposomes’ cargo. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol is taken up by antigen-presenting cells mediated via complement component 1q (C1q) .
Cat. No.: HY-142980
CAS No.: 62700-69-0
Synonyms: Dioleoylphosphatidylglycerol
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DOPG (Dioleoylphosphatidylglycerol) is a negatively charged phosphatidylglycerol phospholipid. DOPG is abundant in prokaryotic cell membranes and mitochondria, and has a low phase transition temperature and a tendency to form stable vesicles. DOPG inhibits the production of inflammatory mediators in macrophages in response to heat shock protein B4 (HSPB4)-activated toll-like receptor 2 (TLR2). DOPG is applicable to studies of membrane biology, drug-membrane interactions (especially in systems targeting negatively charged membranes), construction of drug delivery carriers, as well as research on sterile corneal inflammation and wound healing promotion .
Cat. No.: HY-174940
CAS No.: 1240502-50-4
Cat. No.: HY-142991
CAS No.: 185435-28-3
Synonyms: POPG
1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol (POPG) is an anionic phosphatidylglycerol that often serves as a key component to co-construct model phospholipid bilayers with phosphatidylcholine (e.g., at a 3:1 POPC:POPG ratio) for investigating the structure and dynamics of transmembrane proteins. 1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphatidylglycerol acts as a fundamental material for mimicking the physicochemical properties of biological membranes and enables the elucidation of membrane protein interaction mechanisms .
Cat. No.: HY-148601
CAS No.: 217939-97-4
Synonyms: DSPG
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1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (DSPG) is an anionic (negatively charged) phospholipid . 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol is used to prepare lipid microbubbles as ultrasound contrast agents. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol can be used to construct liposomes as vaccine carriers for the treatment of atherosclerosis. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol is applicable to the research of drug delivery and diagnostic preparations .
Cat. No.: HY-146047
CAS No.: 1666134-58-2
Antibacterial agent 94 (compound 5b) is a potent antibacterial agent. Antibacterial agent 94 show antibacterial activities and show the capability of eradicating MRSA persisters. Antibacterial agent 94 has an effect on bacterial membrane. Antibacterial agent 94 interferes in phosphatidylglycerol (PG) synthesis pathway .
Cat. No.: HY-178476
CAS No.: 3096122-10-7
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Anti-MRSA agent 36 (Compound III13) is an antibacterial agent with strong anti MRSA activity (MIC = 1 μg/mL). Anti-MRSA agent 36 targets phosphatidylglycerol (PG) on bacterial membranes, disrupting membrane integrity, leading to DNA leakage and increased ROS. Anti-MRSA agent 36 has advantages such as low cytotoxicity, low hemolysis, difficulty in inducing drug resistance, and good plasma stability. Anti-MRSA agent 36 can be used for the study of skin abscess and systemic infection models .
Cat. No.: HY-145742S
CAS No.: 326495-47-0
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1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol-d70 (sodium) is deuterium labeled 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol. 1,2-Distearoyl-sn-Glycero-3-Phosphatidylglycerol (sodium) is the component of liposomes for drug delivery .
Cat. No.: HY-W344927
CAS No.: 799268-52-3
Synonyms: (2R)-2,3-Bis(heptadecanoyloxy)propyl 2,3-dihydroxypropyl phosphate sodium
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1,2-Diheptadecanoyl-sn-Glycero-3-Phosphatidylglycerol (sodium) ((2R)-2,3-Bis(heptadecanoyloxy)propyl 2,3-dihydroxypropyl phosphate (sodium)) is an ester product.
Cat. No.: HY-175295A
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Anti-MRSA agent 33 iodide is an anti-Methicillin (HY-121544)-resistant Staphylococcus aureus (MRSA) agent, with MIC values of 2-4 μg/mL. Anti-MRSA agent 33 iodide demonstrates effective biofilm eradication and minimal cytotoxicity toward mammalian cells. Anti-MRSA agent 33 iodide specifically binds to phosphatidylglycerol (PG) on bacterial membranes, leading to membrane disruption, excessive production of ROS, and metabolic collapse, ultimately resulting in bacterial cell death. Anti-MRSA agent 33 iodide reduces bacterial load in a murine skin infection model .
Cat. No.: HY-170423
CAS No.: 322647-40-5
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18:1 (Δ9-Trans) PG is a phosphatidylglycerol with a phosphoglycerol backbone .
Cat. No.: HY-173587
Synonyms: 1,2-Bis(heptanoylthio) glycerophosphatidylglycerol sodium
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1,2-Bis(heptanoylthio)-sn-glycero-3-PG (1,2-Bis(heptanoylthio) glycerophosphatidylglycerol) sodium is a fatty acylthioesterified phosphatidylglycerol derivative that can be used to mimic the action of phospholipases or as a probe molecule for membrane fusion studies .
Cat. No.: HY-169160
Anti-MRSA agent 18 (E17) is an inhibitor of MRSA with MIC values of 2 μg/mL for S. aureus and 4 μg/mL for MRSA, respectively. Anti-MRSA agent 18 interacts with bacterial cell membrane phosphatidylglycerol and cardiolipin, causing changes in cell membrane permeability and polarization, increased intracellular ROS, and DNA and protein leakage, thereby accelerating bacterial death .
Cat. No.: HY-174158
Antibacterial agent 270 (Compound 3e) is an antibacterial agent that acts on bacterial membrane components phosphatidylglycerol (PG), cardiolipin (CL), and bacterial DNA. Antibacterial agent 270 disrupts bacterial membrane structure and binds to DNA to interfere with genetic information transmission. Antibacterial agent 270 is promising for research of infections caused by methicillin-resistant Staphylococcus aureus (MRSA) .
Cat. No.: HY-153924
CAS No.: 319003-15-1
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Di-22:6-BMP is a bisphospholipid and also a structural isomer of phosphatidylglycerol. Di-22:6-BMP serves as a biomarker for drug-induced phospholipidosis in rats .
Cat. No.: HY-183340
CAS No.: 3023862-30-5
Antibacterial agent 341 is an anti-bacterial agent. Antibacterial agent 341 shows broad-spectrum Gram-positive antibacterial activity. Antibacterial agent 341 targets phosphatidylglycerol (PG) and cardiolipin (CL) in bacterial cell membranes, induces sustained depolarization of membranes, and disrupts the cell membrane integrity. Antibacterial agent 341 exhibits anti-infection activity against S. aureus-induced subcutaneous abscesses in mice .
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9,12,15-Octadecatrienoic acid, (1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester, monosodium salt, (9Z,9′Z,12Z,12′Z,15Z,15′Z)-
Cat. No.: HY-147075
CAS No.: 474943-20-9
Synonyms: PG(18:3(9Z,12Z,15Z)/18:3(9Z,12Z,15Z)) sodium
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Tridecanoic acid, (2R)-3-[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]-2-hydroxypropyl ester, sodium salt (1:1)
Cat. No.: HY-W753643
CAS No.: 1246298-10-1
Synonyms: PG(13:0/0:0) sodium
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
