15 Results for "

plasma membrane damage

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "plasma membrane damage" in MCE Product Catalog:

Cat. No.: HY-D0259
CAS No.: 16423-68-0
Synonyms: Erythrosin extra bluish; Tetraiodofluorescein disodium
Research Areas:  

Infection

Erythrosine B (Erythrosin extra bluish; Tetraiodofluorescein) is a visible red dye and insecticide with colorimetric and fluorescent properties. Erythrosine B serves as a membrane-impermeant live-cell dye for Gram-positive and Gram-negative bacteria, primarily staining dead cells with damaged plasma membranes. Erythrosine B exhibits photosensitive larvicidal toxicity against Culex pipiens quinquefasciatus larvae. Erythrosine B is used in live/dead bacterial assays in colorimetric and fluorescent measurements for low-, medium-, and high-throughput experiments, as well as in research related to mosquito-borne diseases and food coloring .
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Cat. No.: HY-B0633D
CAS No.: 9067-32-7
Hyaluronic acid sodium (MW 200-1560) is a biopolymer composed of repeating disaccharide units, with a molecular weight of 200-1560. Hyaluronic acid sodium is a major component of the extracellular matrix (ECM). It is synthesized on the plasma membrane. Hyaluronic acid sodium exerts its effects by binding to receptors CD44 and RHAMM. Hyaluronic acid sodium activates PI3K-Akt signaling. Hyaluronic acid sodium also enhances cell invasion and angiogenesis by promoting or stimulating the binding of proteolytic MMP-9 to the cell surface. Elevated hyaluronic acid levels are associated with tumor cell growth, adhesion, migration, invasion, and angiogenesis in digestive system cancers. Hyaluronic acid sodium is involved in tissue remodeling and rapid cell proliferation in several physiological processes, including embryonic morphogenesis and wound healing. Hyaluronic acid sodium can be used as a regulator of cancer-associated lymphangiogenesis. Hyaluronic acid sodium can be used as a drug delivery carrier for sodium butyrate, enhancing its anti-proliferative activity against breast cancer cell lines. Hyaluronic acid sodium can lubricate the corneal endothelium. Hyaluronic acid sodium can improve tissue hydration and enhance the resistance of cells to mechanical damage. Hyaluronic acid sodium has been conjugated with antibodies to ensure that the active compound continues to exert its effects at the site of inflammation. Hyaluronic acid sodium can be used in research in the fields of osteoarthritis, ophthalmology, cosmetic dermatology, oncology, and liver diseases .
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Cat. No.: HY-B0633E
CAS No.: 9004-61-9
Synonyms: Hyaluronan, low endotoxin; Hyaluronate, low endotoxin
Hyaluronic acid, low endotoxin (Hyaluronan, low endotoxin) is a biopolymer composed of repeating disaccharide units containing low levels of endotoxin. Hyaluronic acid is a major component of the extracellular matrix (ECM). It is synthesized on the plasma membrane. Hyaluronic acid exerts its effects by binding to receptors CD44 and RHAMM. Hyaluronic acid activates PI3K-Akt signaling. Hyaluronic acid also enhances cell invasion and angiogenesis by promoting or stimulating the binding of proteolytic MMP-9 to the cell surface. Elevated hyaluronic acid levels are associated with tumor cell growth, adhesion, migration, invasion, and angiogenesis in digestive system cancers. Hyaluronic acid is involved in tissue remodeling and rapid cell proliferation in several physiological processes, including embryonic morphogenesis and wound healing. Hyaluronic acid can be used as a regulator of cancer-associated lymphangiogenesis. Hyaluronic acid can be used as a drug delivery carrier for sodium butyrate, enhancing its anti-proliferative activity against breast cancer cell lines. Hyaluronic acid can lubricate the corneal endothelium. Hyaluronic acid can improve tissue hydration and enhance the resistance of cells to mechanical damage. Hyaluronic acid has been conjugated with antibodies to ensure that the active compound continues to exert its effects at the site of inflammation. Hyaluronic acid can be used in research in the fields of osteoarthritis, ophthalmology, cosmetic dermatology, oncology, and liver diseases .
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Cat. No.: HY-W087928
CAS No.: 115-40-2
Bromocresol purple is a pH indicator, whose color changes from yellow to purple when the pH increases from 5.2 to 6.8. Bromocresol purple can be used for detecting yeast cells with plasma membrane damage and measuring serum albumin concentrations .
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Cat. No.: HY-D0920
CAS No.: 166196-17-4
TOTO-3 is a cyanine nucleic acid intercalating fluorescent probe that binds to both RNA and DNA (Ex=642 nm, Em=660 nm). TOTO-3 cannot enter intact cells, but can penetrate cells with permeabilized plasma membranes, staining cytoplasmic RNA and nucleoli to distinguish intact cells from damaged ones. TOTO-3 is taken up by macrophages in an ultrasound-independent manner. TOTO-3 accumulates in tumor cells via ultrasound-mediated enhancement of plasma membrane permeability. TOTO-3 supports optical imaging for real-time assessment of plasma membrane integrity, nucleic acid detection, and monitoring of ultrasound-mediated intracellular delivery processes. TOTO-3 is applicable to studies related to rectal cancer .
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Cat. No.: HY-107864
CAS No.: 15905-32-5
Purity:  99.07%
Synonyms: Erythrosin extra bluish free acid; Tetraiodofluorescein
Research Areas:  

Infection

Erythrosine B free acid​ (Erythrosin extra bluish free acid; Tetraiodofluorescein) is a visible red dye and insecticide with colorimetric and fluorescent properties. Erythrosine B free acid serves as a membrane-impermeant live-cell dye for Gram-positive and Gram-negative bacteria, primarily staining dead cells with damaged plasma membranes. Erythrosine B free acid exhibits photosensitive larvicidal toxicity against Culex pipiens quinquefasciatus larvae. Erythrosine B free acid is used in live/dead bacterial assays in colorimetric and fluorescent measurements for low-, medium-, and high-throughput experiments, as well as in research related to mosquito-borne diseases and food coloring .
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Cat. No.: HY-W110790
CAS No.: 62625-30-3
Bromocresol purple sodium is a pH indicator, whose color changes from yellow to purple when the pH increases from 5.2 to 6.8. Bromocresol purple sodium can be used for detecting yeast cells with plasma membrane damage and measuring serum albumin concentrations .
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Cat. No.: HY-151284
CAS No.: 2833772-94-2
Target:  

Bacterial Fungal

Research Areas:  

Infection

Antifungal agent 38 is a geterocyclic disulfide, an antifungal and antibacterial agent. Antifungal agent 38 induces the shrinkage of hyphae, disrupts the integrity of the plasma membrane, and causes the damage and leakage of cell contents .
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Cat. No.: HY-D0259R
CAS No.: 16423-68-0
Synonyms: Erythrosin extra bluish (Standard); Tetraiodofluorescein disodium (Standard)
Research Areas:  

Infection

Erythrosine B (Standard) (Erythrosin extra bluish (Standard); Tetraiodofluorescein disodium (Standard)) is the analytical standard of Erythrosine B (HY-D0259). This product is intended for research and analytical applications. Erythrosine B (Erythrosin extra bluish; Tetraiodofluorescein) is a visible red dye and insecticide with colorimetric and fluorescent properties. Erythrosine B serves as a membrane-impermeant live-cell dye for Gram-positive and Gram-negative bacteria, primarily staining dead cells with damaged plasma membranes. Erythrosine B exhibits photosensitive larvicidal toxicity against Culex pipiens quinquefasciatus larvae. Erythrosine B is used in live/dead bacterial assays in colorimetric and fluorescent measurements for low-, medium-, and high-throughput experiments, as well as in research related to mosquito-borne diseases and food coloring .
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Cat. No.: HY-161823
Target:  

Bacterial

Research Areas:  

Infection

Anti-MRSA agent 13 (Compound 9b) is an agent against methicillin-resistant Staphylococcus aureus (MRSA), exhibiting a minimum inhibitory concentration (MIC) of 0.5–2 μg/mL against clinically isolated MRSA strains. Anti-MRSA agent 13 possesses favorable biosafety, plasma tolerance stability, and a low tendency to develop resistance. Anti-MRSA agent 13 disrupts cell walls and membranes, reduces metabolic activity, causes oxidative damage, affects DNA function, and ultimately leads to MRSA death through multi-target synergies .
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Cat. No.: HY-171936
CAS No.: 1329115-44-7
Synonyms: GM1 (d18:1/C18:0) ammonium; C18 Ganglioside GM1 (d18:1/18:0) ammonium
Target:  

Endogenous Metabolite

Research Areas:  

Neurological Disease

Ganglioside GM1 (ammonium) is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue. Ganglioside GM1 (ammonium) is one of the most abundant gangliosides in the brain which provides neuroprotection. Ganglioside GM1 (ammonium) exhibits anti-inflammatory property. Ganglioside GM1 (ammonium) has a well-balanced amphiphilic behavior. Ganglioside GM1 (ammonium) can reduce the fluidity of the plasma membrane that implies a retention and enrichment of the ganglioside in specific membrane domains that are called lipid rafts. Ganglioside GM1 (ammonium) can modify the process of differentiation, amplifies responses to neurotrophic factors, protects against excitatory amino acid-related neurotoxicity. Ganglioside GM1 (ammonium) can alleviate acute nerve cell damage through blocking cytotoxicity and potentiating neurotophic factors. Ganglioside GM1 (ammonium) can be studied in neurodegenerative diseases such as Alzheimer’s disease .
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Cat. No.: HY-D3609
Target:  

Fluorescent Dye

Research Areas:  

Others

Sulfo-Cy5 HA (MW 200000) is a Sulfo-Cy5-labeled hyaluronic acid. Sulfo-Cy5 is a dye composed of a halogenated Cy5 fluorophore and two sulfonic acid groups .
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Cat. No.: HY-107864A
CAS No.: 12227-78-0
Synonyms: Erythrosin extra bluish aluminum; Tetraiodofluorescein aluminum
Research Areas:  

Infection

Erythrosine B aluminum​ (Erythrosin extra bluish aluminum; Tetraiodofluorescein aluminum) is a visible red dye and insecticide with colorimetric and fluorescent properties. Erythrosine B aluminum serves as a membrane-impermeant live-cell dye for Gram-positive and Gram-negative bacteria, primarily staining dead cells with damaged plasma membranes. Erythrosine B aluminum exhibits photosensitive larvicidal toxicity against Culex pipiens quinquefasciatus larvae. Erythrosine B aluminum is used in live/dead bacterial assays in colorimetric and fluorescent measurements for low-, medium-, and high-throughput experiments, as well as in research related to mosquito-borne diseases and food coloring .
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Cat. No.: HY-P11658
CAS No.: 620948-14-3
Synonyms: Peptoid 1
Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

Anticancer peptoid 1 (Peptoid 1) is a peptoid with antitumor activity. Anticancer peptoid 1 exerts cytotoxicity primarily via plasma membrane damage. Anticancer peptoid 1 exerts cytotoxicity against a broad range of cancer cell lines, including those with multidrug resistance. Anticancer peptoid 1 inhibits tumor growth in a human breast cancer xenotransplantation mouse model without noticeable acute adverse effects. Anticancer peptoid 1 can be used for the research of cancer, such as breast cancer, and prostate cancer .
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Cat. No.: HY-107864R
CAS No.: 15905-32-5
Synonyms: Erythrosin extra bluish free acid (Standard); Tetraiodofluorescein (Standard)
Research Areas:  

Infection

Erythrosine B free acid (Standard) (Erythrosin extra bluish free acid (Standard); Tetraiodofluorescein (Standard)) is the analytical standard of Erythrosine B free acid (HY-107864). This product is intended for research and analytical applications. Erythrosine B free acid​ (Erythrosin extra bluish free acid; Tetraiodofluorescein) is a visible red dye and insecticide with colorimetric and fluorescent properties. Erythrosine B free acid serves as a membrane-impermeant live-cell dye for Gram-positive and Gram-negative bacteria, primarily staining dead cells with damaged plasma membranes. Erythrosine B free acid exhibits photosensitive larvicidal toxicity against Culex pipiens quinquefasciatus larvae. Erythrosine B free acid is used in live/dead bacterial assays in colorimetric and fluorescent measurements for low-, medium-, and high-throughput experiments, as well as in research related to mosquito-borne diseases and food coloring .
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