1. Anti-infection
  2. Bacterial
    Fungal
  3. Antifungal agent 38

Antifungal agent 38 

Cat. No.: HY-151284
Handling Instructions

Antifungal agent 38 is a geterocyclic disulfide, an antifungal and antibacterial agent. Antifungal agent 38 induces the shrinkage of hyphae, disrupts the integrity of the plasma membrane, and causes the damage and leakage of cell contents.

For research use only. We do not sell to patients.

Antifungal agent 38 Chemical Structure

Antifungal agent 38 Chemical Structure

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Antifungal agent 38 is a geterocyclic disulfide, an antifungal and antibacterial agent. Antifungal agent 38 induces the shrinkage of hyphae, disrupts the integrity of the plasma membrane, and causes the damage and leakage of cell contents[1].

In Vitro

Antifungal agent 38 (50 μg/mL) shows anti-fungal activity against 10 pathogenic fungi with inhibition rates of 56.57% (R. solani), 100% (S. sclerotiorum), 55.09% (B. cinerea), 71.23% (F. graminearum), 37.32% (M. oryzae), 50.87% (P. capsici), 100% (A. flavus), 59.75% (P. expansum), 100% (M. fructicola), 65.78% (R. stolonifer), respectively[1].
Antifungal agent 38 (5 μg/mL) damages plasma membrane integrity of M. fructicola[1].
Antifungal agent 38 (100 μg/mL) displays excellent anti-bacterial activity against X. oryzae accc 11602, X. axonpodis[1].
Antifungal agent 38 inhibits fungus growth with EC50s of 17.09 μg/mL (R. solani), 6.34 μg/mL (S. sclerotiorum), 25.24 μg/mL (F. graminearum), >10 μg/mL (A. flavus), 10.42 μg/mL (M. fructicola), 45.71 μg/mL (B. cinerea), respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: M. fructicola
Concentration: 10, 25, 50 μg/mL
Incubation Time: 2, 4, 6 days
Result: Inhibited M. fructicola growth.
In Vivo

Antifungal agent 38 (compound S8) (200 μg/mL) displays equivalent curative and higher protective effects as the positive drug Thiophanate-Methyl (HY-B0842) in vivo[1].
Antifungal agent 38 (50, 100, 200 μg/mL, 30 mL; sprinkling) applies on pears and inhibits M. fructicola growth in vivo[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

200.32

Formula

C8H12N2S2

SMILES

CC(CSSC1=NC=CC=N1)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Antifungal agent 38
Cat. No.:
HY-151284
Quantity:
MCE Japan Authorized Agent: