3 Results for "

porcine liver microsome

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "porcine liver microsome" in MCE Product Catalog:

Cat. No.: HY-N4031
CAS No.: 82375-29-9
Humantenine is a highly toxic indole alkaloid from Gelsemium elegans (Gardn. & Champ.) Benth. that binds to RNA m6A modification regulatory proteins (ALKBH5, METTL). Humantenine stably binds via hydrogen bonding and hydrophobic interactions and disrupts the m6A methylation level of target genes, thereby impairing the expression of intestinal epithelial cell tight junction and cytoskeleton-related genes, causing intestinal barrier dysfunction and significant intestinal cytotoxicity. The intraperitoneal injection LD50 values of Humantenine are <1 mg/kg in mice, 1.2 mg/kg in male rats and 1.5 mg/kg in female rats, respectively. Species differences exist in the metabolism of Humantenine in human, porcine, goat and rat liver microsomes, and demethylation, dehydrogenation and oxidation occur in liver microsomes .
loading...
    loading...
Cat. No.: HY-12835
CAS No.: 1324003-64-6
Purity:  99.64%
Target:  

LPL Receptor

Research Areas:  

Inflammation/Immunology

S1P1 agonist III is an orally active hS1P1 agonist with an EC50 value of 18 nM. S1P1 agonist III shows limited activity against hS1P3. S1P1 agonist III can be used in the research of multiple sclerosis .
loading...
    loading...
Cat. No.: HY-W351643
CAS No.: 1309112-13-7
Target:  

Endogenous Metabolite

Research Areas:  

Others

Repaglinide acyl-beta-D-glucuronide is an acyl glucuronide metabolite of Repaglinide (HY-15209) .
loading...
    loading...