1 Result for "

sclerodermatous

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "sclerodermatous" in MCE Product Catalog:

Cat. No.: HY-17606
CAS No.: 1262414-04-9
Synonyms: ACT-334441
Target:  

LPL Receptor

Research Areas:  

Inflammation/Immunology

Cenerimod (ACT-334441) is a potent, selective and orally active S1P1 receptor modulator, with an EC50 of 1 nM. Cenerimod shows more than 36 fold selctivity for hS1P1 over hS1P2, hS1P3, hS1P4, and hS1P5 receptor subtypes (EC50s=>10000, 228, 2134, and 36 nM, respectively). Cenerimod can attenuate murine experimental autoimmune encephalomyelitis (EAE) and murine sclerodermatous .
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