Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
serotonin 2A (5-HT2A) receptor
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "serotonin 2A (5-HT2A) receptor" in MCE Product Catalog:
Synonyms: VVZ-149 hydrochloride
Target:
Research Areas:
Opiranserin (VVZ-149) hydrochloride, a non-opioid and non-NSAID analgesic candidate, is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, respectively. Opiranserin hydrochloride shows antagonistic activity on rP2X3 (IC50=0.87 μM). Opiranserin hydrochloride is development as an injectable agent for the treatment of postoperative pain .
Cat. No.: HY-168809
CAS No.: 21420-59-7
Target:
Research Areas:
Norbaeocystin is an intermediate/minor metabolite naturally present in the psilocybin biosynthetic pathway of hallucinogenic mushrooms (Psilocybe spp.). Norbaeocystin has weak or no affinity for the serotonin 2A (5-HT2A) receptor and does not induce receptor activation. Norbaeocystin is rapidly metabolized by monoamine oxidase, and thus does not participate in centrally mediated psychedelic effects. Norbaeocystin can be used for studies on biological pathways associated with hallucinogenic effects .
Cat. No.: HY-175511
CAS No.: 2864368-10-3
Target:
Research Areas:
5-HT2A agonist 7 (Compound 45) is an orally active and highly selective serotonin receptor 2A (5-HT2A) agonist (EC50=12 nM). 5-HT2A agonist 7 is promising for research of psychiatric disorders such as depression .
Cat. No.: HY-109067
CAS No.: 1441000-45-8
Synonyms: VVZ-149
Target:
Research Areas:
Opiranserin (VVZ-149), a non-opioid and non-NSAID analgesic candidate, is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, respectively. Opiranserin shows antagonistic activity on rP2X3 (IC50=0.87 μM). Opiranserin is development as an injectable agent for the treatment of postoperative pain .
Cat. No.: HY-P703149
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: HTR2A; serotonin receptor 2A; Prev. HTR2; serotonin 5-HT-2A receptor; 5-HT2A; 5-HT2 receptor; 5-Hydroxytryptamine (serotonin) receptor 2A, G Protein-Coupled; 5-HT-2A; 5-Hydroxytryptamine (serotonin) receptor 2A; 5-Hydroxytryptamine receptor 2A; 5-HT-2
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P703150
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HTR2A; serotonin receptor 2A; Prev. HTR2; serotonin 5-HT-2A receptor; 5-HT2A; 5-HT2 receptor; 5-Hydroxytryptamine (serotonin) receptor 2A, G Protein-Coupled; 5-HT-2A; 5-Hydroxytryptamine (serotonin) receptor 2A; 5-Hydroxytryptamine receptor 2A; 5-HT-2
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-P810892
Synonyms: HTR2; 5-hydroxytryptamine receptor 2A; 5-HT-2; 5-HT-2A; serotonin receptor 2A
Cat. No.: HY-W682464
CAS No.: 96096-53-6
Target:
Research Areas:
4-MeO-MiPT is a serotonin transporter (SERT) inhibitor and serotonin 2A receptor (5-HT2A) agonist with pIC50 and IC50 values of 57 nM and 0.43 nM for human SERT, and pEC50 and EC50 values of 23 nM and 2.3 nM for human 5-HT2A, respectively. 4-MeO-MiPT blocks serotonin uptake via SERT, acts as an agonist at 5-HT2A receptors, and exhibits agonist activity at 5-HT1A, 5-HT1D, 5-HT2B, and 5-HT2C receptors. 4-MeO-MiPT can be used for the research of depression .
Cat. No.: HY-109067AR
CAS No.: 1440796-75-7
Synonyms: VVZ-149 hydrochloride (Standard)
Research Areas:
Opiranserin hydrochloride (Standard) is the analytical standard of Opiranserin (hydrochloride) (HY-109067A). This product is intended for research and analytical applications. Opiranserin (VVZ-149) hydrochloride, a non-opioid and non-NSAID analgesic candidate, is a dual antagonist of glycine transporter type 2 (GlyT2) and serotonin receptor 2A (5HT2A), with IC50s of 0.86 and 1.3 μM, respectively. Opiranserin hydrochloride shows antagonistic activity on rP2X3 (IC50=0.87 μM). Opiranserin hydrochloride is development as an injectable agent for the treatment of postoperative pain .
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
