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skin tumor model

" in MedChemExpress (MCE) Product Catalog:

By Targets:	TNF Receptor (1) Apoptosis (2) Bacterial (1) Biochemical Assay Reagents (7) Calcium Channel (1) DNA/RNA Synthesis (2) Drug Intermediate (1) EBV (1) Endogenous Metabolite (3) Environmental Pollutants (2) Glutathione S-transferase (1) HIV (2) Interleukin Related (3) Isotope-Labeled Compounds (2) Keap1-Nrf2 (1) Lactate Dehydrogenase (1) MMP (3) PKA (3) Quinone Reductase (1) Reactive Oxygen Species (ROS) (1) Reference Standards (2)
By Research Areas:	Cancer (16) Infection (6) Inflammation/Immunology (4) Metabolic Disease (3)

By Targets:

TNF Receptor (1)

Apoptosis (2)

Bacterial (1)

Biochemical Assay Reagents (7)

Calcium Channel (1)

DNA/RNA Synthesis (2)

Drug Intermediate (1)

EBV (1)

Endogenous Metabolite (3)

Environmental Pollutants (2)

Glutathione S-transferase (1)

HIV (2)

Interleukin Related (3)

Isotope-Labeled Compounds (2)

Keap1-Nrf2 (1)

Lactate Dehydrogenase (1)

MMP (3)

PKA (3)

Quinone Reductase (1)

Reactive Oxygen Species (ROS) (1)

Reference Standards (2)

By Research Areas:

Cancer (16)

Infection (6)

Inflammation/Immunology (4)

Metabolic Disease (3)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Targets Recommended: Large Tumor Suppressor (LATS) TNF Receptor BRK

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N1420

Rhamnose 1 Publications Verification L-Rhamnose	Environmental Pollutants Endogenous Metabolite PKA MMP Interleukin Related	Infection Metabolic Disease Cancer
Rhamnose (L-Rhamnose ) is an orally active deoxysugar. Rhamnose can inhibit levels of pro-inflammatory interleukin and matrix metalloproteinases (MMPs) in skin aging models. Rhamnose can promote the phosphorylation levels of PKA substrates and HSL in SVF-derived adipocytes, stimulating PKA signaling. Rhamnose can act against obesity in mice by stimulating fat dopamine receptors and inducing thermogenesis. Rhamnose shows anti-aging effects. Rhamnose monohydrate can be used in the study of Ehrlich’s solid tumors and sarcomas .

HY-W088065

Sodium formate	Environmental Pollutants DNA/RNA Synthesis	Others
Sodium formate acts as a key promoter for heterogeneous nucleation of ZIF crystals and thin film synthesis. It is also recognized as a GRAS substance by the FDA, and serves as a cosmetic preservative and food additive. Sodium formate has low acute oral toxicity (acute oral LD₅₀=7410 mg/kg and acute intravenous LD₅₀=807 mg/kg in mice), with no heritable or carcinogenic effects, but exhibits embryonic developmental toxicity and teratogenicity at high concentrations. Sodium formate may cause moderate irritation to rabbit eyes, is relatively safe to the skin, and does not induce tumor formation in rats in vivo. Sodium formate is rapidly absorbed and oxidized to carbon dioxide in vivo, and forms DNA adducts in specific metabolic deficiency models or upon high-dose exposure .

HY-W010098

Terephthalic acid 1 Publications Verification	Drug Intermediate	Cancer
Terephthalic acid is an isomer and a precursor of polyester PET, which can be used to make clothing and plastics. Terephthalic acid can be used to build skin tumor models .

HY-B1637

Ditiocarb sodium 4 Publications Verification Sodium diethyldithiocarbamate	HIV Biochemical Assay Reagents	Infection Inflammation/Immunology Cancer
Ditiocarb sodium (Sodium diethyldithiocarbamate) is an orally active copper reagent. Ditiocarb sodium exhibits activities such as antioxidation, chelation, anti-tumor effects, immunomodulation, and anti-HIV properties. Ditiocarb sodium can be used in the research of tumors, inflammatory, and immune-related diseases .

HY-N1420A

Rhamnose monohydrate 1 Publications Verification L-Rhamnose monohydrate	Endogenous Metabolite MMP Interleukin Related PKA	Infection Metabolic Disease Cancer
Rhamnose monohydrate (L-Rhamnose monohydrate) is an orally active deoxysugar. Rhamnose monohydrate can inhibit levels of pro-inflammatory interleukin and matrix metalloproteinases (MMPs) in skin aging models. Rhamnose can promote the phosphorylation levels of PKA substrates and HSL in SVF-derived adipocytes, stimulating PKA signaling. Rhamnose monohydrate can act against obesity in mice by stimulating fat dopamine receptors and inducing thermogenesis. Rhamnose monohydrate shows anti-aging effects. Rhamnose monohydrate can be used in the study of Ehrlich’s solid tumors and sarcomas .

HY-B1637A

Ditiocarb sodium,98% 4 Publications Verification Sodium diethyldithiocarbamate,98%	HIV Biochemical Assay Reagents	Infection Inflammation/Immunology Cancer
Ditiocarb sodium,98% (Sodium diethyldithiocarbamate,98%) is an orally active copper reagent. Ditiocarb sodium,98% exhibits activities such as antioxidation, chelation, anti-tumor effects, immunomodulation, and anti-HIV properties. Ditiocarb sodium,98% can be used in the research of tumors, inflammatory, and immune-related diseases .

HY-W010098S1

Terephthalic acid-13C2 1 Publications Verification	Isotope-Labeled Compounds Biochemical Assay Reagents	Cancer
Terephthalic acid- ¹³C₂ is the ¹³C-labeled Terephthalic acid. Terephthalic acid is an isomer and a precursor of polyester PET, which can be used to make clothing and plastics. Terephthalic acid can be used to build skin tumor models .

HY-W250127

Disodium terephthalate 1 Publications Verification Terephthalic acid disodium salt	Biochemical Assay Reagents	Cancer
Disodium terephthalate (Terephthalic acid disodium salt) is an isomer and a precursor of polyester PET, which can be used to make clothing and plastics. Disodium terephthalate can be used to build skin tumor models .

HY-W010098S

Terephthalic acid-d4	Isotope-Labeled Compounds Biochemical Assay Reagents	Cancer
Terephthalic acid-d₄ is the deuterium labeled Terephthalic acid. Terephthalic acid is an isomer and a precursor of polyester PET, which can be used to make clothing and plastics. Terephthalic acid can be used to build skin tumor models .

HY-176798

NCI-006	Lactate Dehydrogenase Reactive Oxygen Species (ROS) Apoptosis	Cancer
NCI-006 is an orally active lactate dehydrogenase (LDH) inhibitor (LDHA IC₅₀ = 0.06 μM; LDHB IC₅₀ = 0.03 μM). NCI-006 inhibits intratumoral LDH activity, lactate production, and tumor growth in a mouse pancreatic cancer model. NCI-006 inhibits glycolysis and induces apoptosis in vitro. NCI-006 enhances the radiosensitivity of glycolytic tumor cell lines while sparing non-glycolytic/normal cells (1522, skin fibroblasts) in combination with ionizing radiation (IR). NCI-006 exhibits synergistic antitumor effects in combination with IACS-010759 (HY-112037) against colorectal and gastric cancers. NCI-006 targets glycolysis by inhibiting lactate dehydrogenase impairs tumor growth in an Ewing sarcoma model .

HY-W010098R

Terephthalic acid (Standard)	Reference Standards Biochemical Assay Reagents	Cancer
Terephthalic acid (Standard) is the analytical standard of Terephthalic acid. This product is intended for research and analytical applications. Terephthalic acid is an isomer and a precursor of polyester PET, which can be used to make clothing and plastics. Terephthalic acid can be used to build skin tumor models .

HY-N8492

Monascorubrin	Bacterial Calcium Channel	Infection Inflammation/Immunology Cancer
Monascorubrin is a compound that can be isolated from Monascus mycelia. Monascorubrin has activities such as anti-inflammatory, anti-tumor, antibacterial, and immunomodulatory. Monascorubrin also has certain embryotoxicity, with an ED₅₀ of 4.3 μg for chicken embryos. Monascorubrin can be used for the research of tumors and inflammatory diseases .

HY-N1420AR

Rhamnose monohydrate (Standard) L-Rhamnose monohydrate (Standard)	Reference Standards Endogenous Metabolite MMP Interleukin Related PKA	Infection Metabolic Disease Cancer
Rhamnose monohydrate (Standard) is the analytical standard of Rhamnose monohydrate (HY-N1420A). Rhamnose monohydrate (L-Rhamnose monohydrate) is an orally active deoxysugar. Rhamnose monohydrate can inhibit levels of pro-inflammatory interleukin and matrix metalloproteinases (MMPs) in skin aging models. Rhamnose can promote the phosphorylation levels of PKA substrates and HSL in SVF-derived adipocytes, stimulating PKA signaling. Rhamnose monohydrate can act against obesity in mice by stimulating fat dopamine receptors and inducing thermogenesis. Rhamnose monohydrate shows anti-aging effects. Rhamnose monohydrate can be used in the study of Ehrlich’s solid tumors and sarcomas .

HY-141439

TBE 31	Keap1-Nrf2 Quinone Reductase Glutathione S-transferase Apoptosis TNF Receptor	Inflammation/Immunology Cancer
TBE 31 is an orally active Keap1/Nrf2 pathway activator and NQO1 inducer with a D_m value of 1.1 nM for NQO1. TBE 31 binds to cysteine residues of Keap1, inhibits ubiquitination and degradation of Nrf2, thereby activating the expression of ARE-dependent genes. TBE 31 induces cytoprotective enzymes including NQO1 and GST isoforms, promotes Nrf2 accumulation, and upregulates Nrf2-regulated genes related to antioxidation and lipid metabolism. TBE 31 inhibits pro-inflammatory responses, formation of AFB1-DNA adducts, endoplasmic reticulum stress, cell apoptosis (apoptosis), hepatic fibrosis, oxidative stress, and the expression of ChREBP. TBE 31 reduces the number of tumors in a mouse model of ultraviolet-induced skin carcinogenesis. TBE 31 enhances nerve growth factor-induced neurite outgrowth. TBE 31 attenuates LPS-induced serum TNF-α levels and immobility time in mice. TBE 31 can be used in research related to liver cancer, skin cancer, inflammation-related depression, and non-alcoholic steatohepatitis .

HY-Y1356

2,4-Dimethoxybenzaldehyde	Biochemical Assay Reagents	Cancer
2,4-Dimethoxybenzaldehyde is a tumor initiator with genotoxic property. 2,4-Dimethoxybenzaldehyde can induce benign papilloma development and converse to squamous cell carcinoma in the skin of susceptible mouse models. 2,4-Dimethoxybenzaldehyde can be used for skin cancer research .

HY-P11417

Epidermal mitosis inhibiting pentapeptide	DNA/RNA Synthesis	Cancer
Epidermal mitosis inhibiting pentapeptide is a five-peptide that acts as a physiological inhibitor of epidermal cell proliferation. This pentapeptide can significantly reduce the DNA synthesis rate and mitotic rate of epidermal keratinocytes. Epidermal mitosis inhibiting pentapeptide moderately enhances the occurrence of skin tumors in skin cancer models, but also shows a higher tendency to promote the regression of already formed tumors. Epidermal mitosis inhibiting pentapeptide can be hydrolyzed by angiotensin-converting enzyme (ACE). Epidermal mitosis inhibiting pentapeptide can be used in cancer process research .

HY-N18106

Amygdalinic acid	EBV	Cancer
Amygdalinic acid (Compound 3) is a glycoside. Amygdalinic acid can be isolated from Persicae Semen. Amygdalinic acid inhibits Epstein-Barr virus early antigen activation. Amygdalinic acid delays two-stage chemical carcinogenesis in mouse skin, reduces papilloma incidence .

Cat. No.	Product Name	Type

HY-W088065

Sodium formate	Biochemical Assay Reagents
Sodium formate acts as a key promoter for heterogeneous nucleation of ZIF crystals and thin film synthesis. It is also recognized as a GRAS substance by the FDA, and serves as a cosmetic preservative and food additive. Sodium formate has low acute oral toxicity (acute oral LD₅₀=7410 mg/kg and acute intravenous LD₅₀=807 mg/kg in mice), with no heritable or carcinogenic effects, but exhibits embryonic developmental toxicity and teratogenicity at high concentrations. Sodium formate may cause moderate irritation to rabbit eyes, is relatively safe to the skin, and does not induce tumor formation in rats in vivo. Sodium formate is rapidly absorbed and oxidized to carbon dioxide in vivo, and forms DNA adducts in specific metabolic deficiency models or upon high-dose exposure .

Sodium formate

Biochemical Assay Reagents

Sodium formate acts as a key promoter for heterogeneous nucleation of ZIF crystals and thin film synthesis. It is also recognized as a GRAS substance by the FDA, and serves as a cosmetic preservative and food additive. Sodium formate has low acute oral toxicity (acute oral LD₅₀=7410 mg/kg and acute intravenous LD₅₀=807 mg/kg in mice), with no heritable or carcinogenic effects, but exhibits embryonic developmental toxicity and teratogenicity at high concentrations. Sodium formate may cause moderate irritation to rabbit eyes, is relatively safe to the skin, and does not induce tumor formation in rats in vivo. Sodium formate is rapidly absorbed and oxidized to carbon dioxide in vivo, and forms DNA adducts in specific metabolic deficiency models or upon high-dose exposure .

HY-W250127

Disodium terephthalate 1 Publications Verification Terephthalic acid disodium salt	Biochemical Assay Reagents
Disodium terephthalate (Terephthalic acid disodium salt) is an isomer and a precursor of polyester PET, which can be used to make clothing and plastics. Disodium terephthalate can be used to build skin tumor models .

Cat. No.	Product Name	Target	Research Area

HY-P11417

Epidermal mitosis inhibiting pentapeptide	DNA/RNA Synthesis	Cancer
Epidermal mitosis inhibiting pentapeptide is a five-peptide that acts as a physiological inhibitor of epidermal cell proliferation. This pentapeptide can significantly reduce the DNA synthesis rate and mitotic rate of epidermal keratinocytes. Epidermal mitosis inhibiting pentapeptide moderately enhances the occurrence of skin tumors in skin cancer models, but also shows a higher tendency to promote the regression of already formed tumors. Epidermal mitosis inhibiting pentapeptide can be hydrolyzed by angiotensin-converting enzyme (ACE). Epidermal mitosis inhibiting pentapeptide can be used in cancer process research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1420

Rhamnose 1 Publications Verification L-Rhamnose	Structural Classification Classification of Application Fields Plants Endogenous metabolite Sweeteners Monosaccharides Food Research Microorganisms other families Disease Research Fields Saccharides Source Classification Cancer	Environmental Pollutants Endogenous Metabolite PKA MMP Interleukin Related
Rhamnose (L-Rhamnose ) is an orally active deoxysugar. Rhamnose can inhibit levels of pro-inflammatory interleukin and matrix metalloproteinases (MMPs) in skin aging models. Rhamnose can promote the phosphorylation levels of PKA substrates and HSL in SVF-derived adipocytes, stimulating PKA signaling. Rhamnose can act against obesity in mice by stimulating fat dopamine receptors and inducing thermogenesis. Rhamnose shows anti-aging effects. Rhamnose monohydrate can be used in the study of Ehrlich’s solid tumors and sarcomas .

HY-W010098

Terephthalic acid 1 Publications Verification	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields	Drug Intermediate
Terephthalic acid is an isomer and a precursor of polyester PET, which can be used to make clothing and plastics. Terephthalic acid can be used to build skin tumor models .

HY-N1420A

Rhamnose monohydrate 1 Publications Verification L-Rhamnose monohydrate	Microorganisms other families Classification of Application Fields Plants Disease Research Fields Saccharides Monosaccharides Source Classification Cancer	Endogenous Metabolite MMP Interleukin Related PKA
Rhamnose monohydrate (L-Rhamnose monohydrate) is an orally active deoxysugar. Rhamnose monohydrate can inhibit levels of pro-inflammatory interleukin and matrix metalloproteinases (MMPs) in skin aging models. Rhamnose can promote the phosphorylation levels of PKA substrates and HSL in SVF-derived adipocytes, stimulating PKA signaling. Rhamnose monohydrate can act against obesity in mice by stimulating fat dopamine receptors and inducing thermogenesis. Rhamnose monohydrate shows anti-aging effects. Rhamnose monohydrate can be used in the study of Ehrlich’s solid tumors and sarcomas .

HY-W010098R

Terephthalic acid (Standard)	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Reference Standards Biochemical Assay Reagents
Terephthalic acid (Standard) is the analytical standard of Terephthalic acid. This product is intended for research and analytical applications. Terephthalic acid is an isomer and a precursor of polyester PET, which can be used to make clothing and plastics. Terephthalic acid can be used to build skin tumor models .

HY-N8492

Monascorubrin	Infection Microorganisms Classification of Application Fields Ketones, Aldehydes, Acids Disease Research Fields Source Classification	Bacterial Calcium Channel
Monascorubrin is a compound that can be isolated from Monascus mycelia. Monascorubrin has activities such as anti-inflammatory, anti-tumor, antibacterial, and immunomodulatory. Monascorubrin also has certain embryotoxicity, with an ED₅₀ of 4.3 μg for chicken embryos. Monascorubrin can be used for the research of tumors and inflammatory diseases .

HY-N1420AR

Rhamnose monohydrate (Standard) L-Rhamnose monohydrate (Standard)	Structural Classification Microorganisms other families Plants Saccharides Monosaccharides Source Classification	Reference Standards Endogenous Metabolite MMP Interleukin Related PKA
Rhamnose monohydrate (Standard) is the analytical standard of Rhamnose monohydrate (HY-N1420A). Rhamnose monohydrate (L-Rhamnose monohydrate) is an orally active deoxysugar. Rhamnose monohydrate can inhibit levels of pro-inflammatory interleukin and matrix metalloproteinases (MMPs) in skin aging models. Rhamnose can promote the phosphorylation levels of PKA substrates and HSL in SVF-derived adipocytes, stimulating PKA signaling. Rhamnose monohydrate can act against obesity in mice by stimulating fat dopamine receptors and inducing thermogenesis. Rhamnose monohydrate shows anti-aging effects. Rhamnose monohydrate can be used in the study of Ehrlich’s solid tumors and sarcomas .

HY-N18106

Amygdalinic acid	Structural Classification Prunus persica L. Ketones, Aldehydes, Acids Rosaceae Plants Source Classification	EBV
Amygdalinic acid (Compound 3) is a glycoside. Amygdalinic acid can be isolated from Persicae Semen. Amygdalinic acid inhibits Epstein-Barr virus early antigen activation. Amygdalinic acid delays two-stage chemical carcinogenesis in mouse skin, reduces papilloma incidence .

Cat. No.	Product Name	Chemical Structure

HY-W010098S1

Terephthalic acid-13C2 1 Publications Verification
Terephthalic acid- ¹³C₂ is the ¹³C-labeled Terephthalic acid. Terephthalic acid is an isomer and a precursor of polyester PET, which can be used to make clothing and plastics. Terephthalic acid can be used to build skin tumor models .

HY-W010098S

Terephthalic acid-d4
Terephthalic acid-d₄ is the deuterium labeled Terephthalic acid. Terephthalic acid is an isomer and a precursor of polyester PET, which can be used to make clothing and plastics. Terephthalic acid can be used to build skin tumor models .

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skin tumor model

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