Terephthalic acid-13C2
Based on 1 publication(s) in Google Scholar
Terephthalic acid-13C2 is the 13C-labeled Terephthalic acid. Terephthalic acid is an isomer and a precursor of polyester PET, which can be used to make clothing and plastics. Terephthalic acid can be used to build skin tumor models.
For research use only. We do not sell to patients.
- Purity: 99.60%
- CAS No.: 121191-53-5
- Formula: C613C2H6O4
- Molecular Weight:168.12
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Terephthalic acid-13C2
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 121191-53-5
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Unlabeled Cas 100-21-0
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Appearance Solid
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Molecular Weight 168.12
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Formula C613C2H6O4
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Color White to off-white
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SMILES
O[13C](C1=CC=C(C=C1)[13C](O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Environ Sci Technol
Complementary Bacterial Functions Enhance Mineralization of Aromatic Aliphatic Copolyesters within a Marine Microbial Consortium. [Abstract]2026 Feb 28. PMID: 41762619
Solvent & Solubility
DMSO : 125 mg/mL (743.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Heck HD, et al. The induction of bladder stones by terephthalic acid, dimethyl terephthalate, and melamine (2,4,6-triamino-s-triazine) and its relevance to risk assessment. Regul Toxicol Pharmacol. 1985 Sep;5(3):294-313. [Content Brief]
[3]. Cui L, et al. Deregulation of the p16-cyclin D1/cyclin-dependent kinase 4-retinoblastoma pathway involved in the rat bladder carcinogenesis induced by terephthalic acid-calculi. Urol Res. 2006 Oct;34(5):321-8. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.9481 mL | 29.7407 mL | 59.4813 mL | 148.7033 mL |
| 5 mM | 1.1896 mL | 5.9481 mL | 11.8963 mL | 29.7407 mL | |
| 10 mM | 0.5948 mL | 2.9741 mL | 5.9481 mL | 14.8703 mL | |
| 15 mM | 0.3965 mL | 1.9827 mL | 3.9654 mL | 9.9136 mL | |
| 20 mM | 0.2974 mL | 1.4870 mL | 2.9741 mL | 7.4352 mL | |
| 25 mM | 0.2379 mL | 1.1896 mL | 2.3793 mL | 5.9481 mL | |
| 30 mM | 0.1983 mL | 0.9914 mL | 1.9827 mL | 4.9568 mL | |
| 40 mM | 0.1487 mL | 0.7435 mL | 1.4870 mL | 3.7176 mL | |
| 50 mM | 0.1190 mL | 0.5948 mL | 1.1896 mL | 2.9741 mL | |
| 60 mM | 0.0991 mL | 0.4957 mL | 0.9914 mL | 2.4784 mL | |
| 80 mM | 0.0744 mL | 0.3718 mL | 0.7435 mL | 1.8588 mL | |
| 100 mM | 0.0595 mL | 0.2974 mL | 0.5948 mL | 1.4870 mL |
Terephthalic acid-13C2 Related Classifications
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