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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
25 Results for "
somatostatin analog
" in MedChemExpress (MCE) Product Catalog:
Products (25)
25 Results for "somatostatin analog" in MCE Product Catalog:
17
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Cardiovascular Disease Inflammation/Immunology Endocrinology Cancer
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1 Cited Publications
Cat. No.: HY-P1206
CAS No.: 174688-78-9
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CH 275 is a peptidic somatostatin analog that acts as an agonist of SST1 (IC50 = 30.9 nM, Ki = 52 nM). The IC50 values of CH 275 for sst3, sst4, sst2, and sst5 are 345 nM, >1 μM, >10 μM, and >10 μM, respectively. CH 275 binds to SSTR1 via the IAmp9-Asp137 ion pair interaction and the hydrophobic interaction between the isopropyl group of IAmp9 and Leu107, and reduces the extracellular acidification rate. CH 275 induces weak sst1 internalization, exerts immunosuppressive effects on macrophages, and decreases macrophage viability, MCP-1 expression/secretion, and IL-8 secretion, but does not alter proMMP-9 secretion or IL-8 mRNA levels. CH 275 reduces hippocampal β-amyloid levels and alleviates plaque pathology without inducing hippocampal microglial activation. CH 275 is used in research on Alzheimer's disease, Parkinson's disease, and depression .
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Synonyms: MK-678; L-363586
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Cat. No.: HY-P10239
CAS No.: 302794-43-0
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Cat. No.: HY-P3124A
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Cat. No.: HY-P2022
CAS No.: 138661-02-6
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Cat. No.: HY-P3901
CAS No.: 77909-99-0
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Cat. No.: HY-P3124
CAS No.: 182153-96-4
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Cat. No.: HY-W035399S
Cat. No.: HY-P4555
CAS No.: 340821-13-8
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Cat. No.: HY-P10239A
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Cat. No.: HY-P2434
CAS No.: 846569-60-6
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Cat. No.: HY-P2229
CAS No.: 119719-11-8
Synonyms: SDZ CO 611
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Cat. No.: HY-P3902
CAS No.: 58976-46-8
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Cat. No.: HY-P3955
CAS No.: 139668-78-3
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Cat. No.: HY-W106325
CAS No.: 2044709-90-0
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Cat. No.: HY-W035399S1
CAS No.: 2708340-91-2
Cat. No.: HY-Y1804S
CAS No.: 2714413-18-8
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
