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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
thyroid-stimulating hormone (TSH)
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "thyroid-stimulating hormone (TSH)" in MCE Product Catalog:
4
4 Cited Publications
Cat. No.: HY-P0002
CAS No.: 24305-27-9
Synonyms: Thyrotropin-releasing-hormone; TRH
4
4 Cited Publications
Cat. No.: HY-P0002A
CAS No.: 120876-23-5
Synonyms: Thyrotropin-releasing-hormone acetate; TRH acetate
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Research Areas:
Metabolic Disease Inflammation/Immunology Endocrinology Cancer
Thyrotropin (TSH, Pretiron) is a thyroid-stimulating hormone produced by thyrotrope cells in the anterior pituitary gland. Thyrotropin regulates the endocrine function of the thyroid. Thyrotropin induces transcriptional regulation of TH-gatekeeper genes in tanycytes through the Tshr/Gαq/PKC pathway. Thyrotropin prevents Apoptosis. Thyrotropin has an association of low levels with increased bone remodeling, reduced bone mass and a high fracture risk in mice. Thyrotropin is promising for research of skeletal remodeling, hyperthyroidism .
Cat. No.: HY-P991202
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Doxylamine succinate is a first-generation antihistamine and acts as a histamine H1 receptor antagonist. Doxylamine succinate is orally active, possessing analgesic and hypnotic activities. Doxylamine succinate enhances the activities of CYP2B, CYP2A, CYP3A and thyroxine-glucuronosyltransferase via promoting substrate hydroxylation and thyroxine metabolic pathways. Doxylamine succinate decreases serum thyroxine (T4) level and elevates serum thyroid-stimulating hormone (TSH) level. Doxylamine succinate induces liver enlargement and increases the activities of hepatic microsomal cytochrome P450, cytochrome b5 and NADPH-cytochrome c reductase. Doxylamine succinate can be used for the research of nausea, allergy, insomnia .
Cat. No.: HY-153213A
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Org 274178-0 is a selective thyroid-stimulating hormone receptor (TSHR) antagonist with a pIC50 value for TSHR is 5.03. Org 274178-0 inhibits the activation of cAMP signaling pathway and phospholipase C (PLC) signaling pathway mediated by thyroid-stimulating hormone (TSH) and TSH receptor-stimulating immunoglobulins (TSIs). Org 274178-0 is promising for research of Graves’ disease and Graves’ ophthalmopathy .
Cat. No.: HY-164764
CAS No.: 1067189-44-9
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ADX61623 is a potent follicle stimulating hormone (FSH) receptor (FSHR) negative allosteric modulator (NAM). ADX61623 shows luteinizing hormone receptor (LH-R) activity and is not active on thyroid-stimulating hormone (TSH) receptors. ADX61623 can be used for the study of estrogen dependent disease .
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Bovine Thyrotropin is a pituitary glycoprotein hormone derived from cattle, with identical properties to thyroid-stimulating hormone (TSH). Bovine Thyrotropin stimulates thyroid function and is used to differentiate between primary and secondary hypothyroidism. Bovine Thyrotropin can induce increased radioactive iodine uptake in metastatic thyroid cancer lesions, and long-term administration leads to the production of neutralizing antibodies and hemagglutinating antibodies. Bovine Thyrotropin is applicable to research related to metastatic thyroid cancer .
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Doxylamine is a first-generation antihistamine and acts as a histamine H1 receptor antagonist. Doxylamine is orally active, possessing analgesic and hypnotic activities. Doxylamine enhances the activities of CYP2B, CYP2A, CYP3A and thyroxine-glucuronosyltransferase via promoting substrate hydroxylation and thyroxine metabolic pathways. Doxylamine decreases serum thyroxine (T4) level and elevates serum thyroid-stimulating hormone (TSH) level. Doxylamine induces liver enlargement and increases the activities of hepatic microsomal cytochrome P450, cytochrome b5 and NADPH-cytochrome c reductase. Doxylamine can be used for the research of nausea, allergy, insomnia .
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Doxylamine succinate (Standard) is the analytical standard of Doxylamine succinate (HY-A0069). This product is intended for research and analytical applications. Doxylamine succinate is a first-generation antihistamine and acts as a histamine H1 receptor antagonist. Doxylamine succinate is orally active, possessing analgesic and hypnotic activities. Doxylamine succinate enhances the activities of CYP2B, CYP2A, CYP3A and thyroxine-glucuronosyltransferase via promoting substrate hydroxylation and thyroxine metabolic pathways. Doxylamine succinate decreases serum thyroxine (T4) level and elevates serum thyroid-stimulating hormone (TSH) level. Doxylamine succinate induces liver enlargement and increases the activities of hepatic microsomal cytochrome P450, cytochrome b5 and NADPH-cytochrome c reductase. Doxylamine succinate can be used for the research of nausea, allergy, insomnia .
Cat. No.: HY-107380A
Purity: 99.69%
Synonyms: A-42872 TFA
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Cat. No.: HY-P81507A
Synonyms: LGR3; TSHR; Thyrotropin Receptor; thyroid-stimulating hormone receptor (TSH-R)
Cat. No.: HY-P706294
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ¹⁵N-Thyrotropin; ¹⁵N-Thyrotropic hormone; ¹⁵N-thyroid-stimulating hormone; ¹⁵N-TSH; TSHB; thyroid stimulating hormone Beta; thyroid stimulating hormone Subunit Beta; TSH-B; Thyrotropin Subunit Beta; Thyrotropin Alfa; Thyrotropin Beta Chain; TSH-BETA; thyroid-stimulating hormone Subunit Beta; TSH-Beta
Species:
Human
Source:
E. coli
Cat. No.: HY-A0069AS
CAS No.: 1173020-59-1
Cat. No.: HY-P704946
Purity: Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: TSHR; LGR3; Thyrotropin receptor; thyroid-stimulating hormone receptor; TSH-R; CHNG1; HTSHR-I; TSHR Protein; Thyrotropin Receptor-I, HTSHR-I; Seven Transmembrane Helix Receptor; TSH Receptor; thyroid stimulating hormone Receptor
Species:
Human
Source:
HEK293
Cat. No.: HY-A0069S
CAS No.: 1216840-94-6
Cat. No.: HY-P74486Y
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: TSHR; LGR3; Thyrotropin receptor; thyroid-stimulating hormone receptor; TSH-R; CHNG1; HTSHR-I; TSHR Protein; Thyrotropin Receptor-I, HTSHR-I; Seven Transmembrane Helix Receptor; TSH Receptor; thyroid stimulating hormone Receptor
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-187261S
Cat. No.: HY-P85956
Synonyms: Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin subunit alpha, Follicle-stimulating hormone alpha chain, Follitropin alpha chain, Luteinizing hormone alpha chain, Lutropin alpha chain, thyroid-stimulating hormone alpha chain, Thyrotropin alpha chain, CG-alpha, FSH-alpha, LSH-alpha, TSH-alpha, CGA
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
