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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
transfer RNA
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "transfer RNA" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-N7068
CAS No.: 115074-43-6
Synonyms: BRL-4910A calcium hydrate; Pseudomonic acid calcium hydrate
Category:
Microorganisms Antibiotics Disease Research Antibacterial Disease Research Fields Inflammation/Immunology Other Antibiotics
Target:
Cat. No.: HY-W008915
CAS No.: 34393-59-4
Synonyms: CDP
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-W244398
CAS No.: 13239-97-9
Research Areas:
2-Thiocytidine is a natural thionucleoside in prokaryotic tRNA, which is biosynthesized under the catalysis of intracellular sulfur transferase systems and possesses multiple activities such as metal coordination and nucleic acid conformation regulation. 2-Thiocytidine forms stable Zn 2+ and Cd 2+ complexes via its (C2) S group, with partial involvement of N3; metal binding acidifies the deprotonation process of (C4) NH2. 2-Thiocytidine can be used in related research in various fields including nanotechnology and click chemistry for interstrand DNA crosslinking .
Synonyms: DEAE-dextran, MW 500000 hydrochloride, from bacterial (Leuconostoc mesenteroides); Diethylaminoethyl-dextran, MW 500000 hydrochloride
Target:
Research Areas:
3'-NH2-ATP, an ATP analogue, is a potent and competitive inhibitor of ATP, with a Ki of 2.3 μM. 3'-NH2-ATP can be used to synthesis of 3′-Amino-3′-deoxy transfer RNA by incorporation into the 3' terminus of tRNA-C-C .
Cat. No.: HY-W008915R
CAS No.: 34393-59-4
Synonyms: CDP (Standard)
Target:
Cat. No.: HY-100496
CAS No.: 24751-69-7
Synonyms: 4'-Fluoro-5'-O-sulfamoyladenosine; NSC 521007
Category:
Infection Microorganisms Antibiotics Anti-parasitic Disease Research Disease Research Fields Other Antibiotics
Target:
Cat. No.: HY-175454
Research Areas:
YH-0623 is an orally active mitochondrial RNA polymerase (POLRMT) inhibitor (IC50 = 50.48 nM, Nanoluciferase Bioluminescence Resonance Energy Transfer (NanoBRET) assay). YH-0623 exhibits antiproliferative effects on 22Rv1 cells by reducing the expression of mitochondrial-related genes. YH-0623 inhibits 22Rv1 cell growth, colony formation, and the expression of OXPHOS-related proteins. YH-0623 significantly inhibits tumor growth in a prostate cancer xenograft mouse model. YH-0623 is indicated for prostate cancer research .
Cat. No.: HY-B0958A
CAS No.: 104486-81-9
Synonyms: BRL-4910A calcium; Pseudomonic acid calcium
Target:
Research Areas:
Mupirocin (BRL-4910A, Pseudomonic acid) calcium is an orally active antibiotic isolated from Pseudomonas fluorescens. Mupirocin calcium apparently exerts its antimicrobial activity by reversibly inhibiting isoleucyl-transfer RNA, thereby inhibiting bacterial protein and RNA synthesis .
Target:
Research Areas:
Histidyl-tRNA synthetase, human is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. Histidyl-tRNA synthetase has been found to act as a particularly important antigen in autoimmune diseases such as rheumatic arthritis or myositis .
Cat. No.: HY-N7068R
CAS No.: 115074-43-6
Synonyms: BRL-4910A calcium hydrate (Standard); Pseudomonic acid calcium hydrate (Standard)
Target:
Cat. No.: HY-E71729
Synonyms: RNA m22G Demethylase (D135S/L118V)
Target:
Research Areas:
AlkB (D135S/L118V), Nuclease-free (RNA m22G Demethylase (D135S/L118V)) is a nuclease-free modified demethylase. AlkB (D135S/L118V), Nuclease-free exhibits catalytic activity toward N2,N2-dimethylguanosine (m22G), N1-methylguanosine (m1G) and N1-methyladenosine (m1A). AlkB (D135S/L118V), Nuclease-free efficiently removes m1G and m1A modifications on RNA, and can also selectively convert m22G to N2-methylguanosine (m2G), thereby significantly reducing the level of m22G in transfer RNA (tRNA). AlkB (D135S/L118V), Nuclease-free greatly reduces sequencing bias and improves the efficiency of high-throughput tRNA sequencing .
Cat. No.: HY-W746941
CAS No.: 52049-48-6
Synonyms: ms2io6A; cis-2-Methylthioribosylzeatin
Target:
Research Areas:
2-Methylthio-cis-zeatin riboside (ms2io6A) , a hypermodified adenosine derivative, is present in the transfer RNA of Salmonella ryphimurium.
Cat. No.: HY-D3364
Research Areas:
RL480 is a green-emitting RNA fluorescent dye used for selective RNA labeling and imaging. RL480 contains an acylimidazole reactive group that undergoes selective acylation with the 2′-OH group of RNA ribose, and restricts intramolecular rotation through covalent binding to relieve the TICT quenching effect, thereby generating a fluorescence enhancement signal. RL480 enables selective fluorescent labeling of RNA over DNA, and is applicable to RNA gel detection, real-time RNA synthesis monitoring and live-cell RNA imaging. The detection wavelengths are Ex/Em = 480 nm/514 nm .
Cat. No.: HY-D3365
Target:
Research Areas:
RL560 is a red-emitting RNA fluorescent dye used for RNA-selective labeling and live-cell RNA imaging. RL560 achieves RNA-selective fluorescence turn-on via covalent acylation between its acylimidazole reactive group and the 2′-OH of RNA ribose, as well as fluorescence signal enhancement through restriction of TICT molecular motion. RL560 is applicable for RNA imaging and multicolor RNA detection, with detection wavelengths of Ex/Em = 560/639 nm .
Cat. No.: HY-202273
CAS No.: 37280-35-6
Capreomycin IA is a bactericidal agent targeting bacterial ribosomes, with activity limited primarily to mycobacteria. Capreomycin IA blocks translocation of peptidyl-transfer RNA from the A to the P site to inhibit protein synthesis. Capreomycin IA exerts activity against Mycobacterium tuberculosis. Capreomycin IA can be used for the research of tuberculosis .
Cat. No.: HY-D3362
Research Areas:
RL420 is an RNA-selective fluorescent covalent probe that binds covalently to the 2′-hydroxyl group of RNA via an acylimidazole-mediated reaction. RL420 has excitation/emission wavelengths of 420/452 nm, exhibits a 150-fold selectivity for RNA over DNA, and shows high labeling efficiency. RL420 can be used in studies related to in vitro RNA labeling, gel imaging, and blue fluorescent imaging of RNA in fixed cells (e.g., nucleoli) .
Cat. No.: HY-W090961
CAS No.: 1192027-04-5
Target:
Research Areas:
DDTT is a highly efficient sulfur transfer reagent for the synthesis of phosphorothioate oligonucleotides. DDTT serves as a collective detection indicator for total organochlorine pesticide residues consisting of DDT, DDE and DDD .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
