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vitamin K2

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By Targets:	Apoptosis (1) Autophagy (1) Bacterial (1) Biochemical Assay Reagents (1) Drug Derivative (3) Endogenous Metabolite (8) Environmental Pollutants (1) Interleukin Related (1) Isotope-Labeled Compounds (7) Liposome (1) NF-κB (3) Reference Standards (5) TGF-beta/Smad (1)
By Research Areas:	Cancer (6) Cardiovascular Disease (4) Infection (1) Inflammation/Immunology (4) Metabolic Disease (4)
Oligonucleotides:	Liposome (1)

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Isotope-Labeled Compounds

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Targets Recommended: VD/VDR VKOR

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

HY-B0332

Menadione 25+ Cited Publications vitamin K3	Environmental Pollutants Endogenous Metabolite	Cancer
Menadione is a naphthoquinone that is converted into active vitamin K2 in the body. Menadione is a potential anticancer agent and radiosensitizer .

HY-112499

Menaquinone-7 3 Publications Verification vitamin K2-7; vitamin K2(35); vitamin MK-7	TGF-beta/Smad	Cardiovascular Disease
Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs (orally active), is originally discovered as the anti-hemorrhagic factors. Menaquinone-7 inhibits osteoclast bone resorption in vitro and stimulates bone formation in femoral tissue of aged female rats. Menaquinone-7 has a well-researched potential in the prevention of aging-induced bone degeneration. Menaquinone-7 is also a pharmacological option for activating Gla matrix protein and intervening in the progression of calcific aortic stenosis (CAVS) .

HY-W011474

Geranylgeraniol	NF-κB	Inflammation/Immunology
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model .

HY-B2156

Menaquinone-4 5+ Cited Publications vitamin K2(MK-4); Menaquinone K4	Endogenous Metabolite	Cancer
Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.

HY-109569

Vitamin K2	Autophagy Apoptosis Interleukin Related	Metabolic Disease Inflammation/Immunology Cancer
Vitamin K2 is an orally active proliferation inhibitor. Vitamin K2 induces Autophagy and Apoptosis. Vitamin K2 reduces the levels of proinflammatory cytokines (such as IL-1β, TNF-α, and IL-6). Vitamin K2 inhibits cell growth in leukemia cells. Vitamin K2 can be used for the research of involutional osteoporosis, non-alcoholic fatty liver disease, ulcerative colitis, acute myeloid leukemia, myelodysplastic syndromes, and hepatocellular carcinoma .

HY-B0332R

Menadione (Standard) vitamin K3 (Standard)	Reference Standards Endogenous Metabolite	Others
Menadione (Standard) is the analytical standard of Menadione. This product is intended for research and analytical applications. Menadione is a naphthoquinone that is converted into active vitamin K2 in the body. Menadione is a potential anticancer agent and radiosensitizer .

HY-131501

Menaquinone 9	Drug Derivative	Metabolic Disease
Menaquinone 9 is a vitamin K2 (HY-109569) analog. Menaquinone 9 acts as a prothrombogenic agent and functional electron transfer component in nitrate reductase .

HY-B2156S

Menaquinone-4-d7 vitamin K2(MK-4)-d₇; Menaquinone K4-d₇	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
Menaquinone-4-d₇ (Vitamin K2(MK-4)-d7) is the deuterium labeled Menaquinone-4. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.

HY-B0332S

Menadione-d3 vitamin K3-d₃	Isotope-Labeled Compounds Endogenous Metabolite	Others
Menadione-d₃ is the deuterium labeled Menadione. Menadione, a synthetic naphthoquinone, can be converted to active vitamin K2 in vivo.

HY-112499S

Menaquinone-7-d7 vitamin K2-7-d₇; vitamin K2(35)-d₇; vitamin MK-7-d₇	Isotope-Labeled Compounds	Cardiovascular Disease
Menaquinone-7-d₇ is the deuterium labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors . Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins . Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS) .

HY-W011474R

Geranylgeraniol (Standard)	Reference Standards NF-κB	Inflammation/Immunology
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model [4].

HY-112499R

Menaquinone-7 (Standard) 3 Publications Verification vitamin K2-7(Standard); vitamin K2(35)(Standard); vitamin MK-7 (Standard)	Endogenous Metabolite Reference Standards	Cardiovascular Disease
Menaquinone-7 (Standard) is the analytical standard of Menaquinone-7. This product is intended for research and analytical applications. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs (orally active), is originally discovered as the anti-hemorrhagic factors. Menaquinone-7 inhibits osteoclast bone resorption in vitro and stimulates bone formation in femoral tissue of aged female rats. Menaquinone-7 has a well-researched potential in the prevention of aging-induced bone degeneration. Menaquinone-7 is also a pharmacological option for activating Gla matrix protein and intervening in the progression of calcific aortic stenosis (CAVS) .

HY-138137

Menaquinone 6	Bacterial	Infection
Menaquinone 6 is a active product found in Wolinella succinogenes. Menaquinone 6 is a form of vitamin K2 (HY-109569) that has antimicrobial activity .

HY-177831

*Liposomal Vitamin* K2**	Liposome	Metabolic Disease
Liposomal Vitamin K2 is a specialized delivery system that encapsulates vitamin K2 within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of vitamin K2. Vitamin K2 (menaquinone-7) is?a fat-soluble nut

HY-B2156R

Menaquinone-4 (Standard) vitamin K2(MK-4) (Standard); Menaquinone K4 (Standard)	Reference Standards Endogenous Metabolite	Cancer
Menaquinone-4 (Standard) is the analytical standard of Menaquinone-4. This product is intended for research and analytical applications. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.

HY-112499S1

Menaquinone-7-13C6 vitamin K2-7-¹³C₆; vitamin K2(35)-¹³C₆; vitamin MK-7-¹³C₆	Isotope-Labeled Compounds	Cardiovascular Disease
Menaquinone-7- ¹³C₆ is the ¹³C-labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors . Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins . Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS) .

HY-W769519

Vitamin K2(5)-D7	Isotope-Labeled Compounds	Others
Vitamin K2(5)-d₇ is the deuterium labeled Vitamin K2(5) (HY-134537).

HY-134537

Vitamin K2(5)	Drug Derivative	Others
Vitamin K2 (5) (Compound 1) is a prenylogue of the Vitamin K2 (HY-109569) series that can be found in the heartwood of Tabebuia avellanedae .

HY-131501R

Menaquinone 9 (Standard)	Drug Derivative Reference Standards	Metabolic Disease
Menaquinone 9 (Standard) is the analytical standard of Menaquinone 9. This product is intended for research and analytical applications. Menaquinone 9 is a vitamin K2 (HY-109569) analog. Menaquinone 9 acts as a prothrombogenic agent and functional electron transfer component in nitrate reductase .

HY-W011474S

Geranylgeraniol-d5	Isotope-Labeled Compounds NF-κB	Inflammation/Immunology
Geranylgeraniol-d₅ is the deuterium labeled Geranylgeraniol (HY-W011474). Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model .

HY-E71158

1,4-Dihydroxy-2-naphthoyl-CoA synthase	Biochemical Assay Reagents	Others
1,4-Dihydroxy-2-naphthoyl-CoA synthase (EC 4.1.3.36) is involved in the synthesis of 1,4-Dihydroxy-2-naphthoate, a branch point metabolite leading to the biosynthesis of menaquinone (vitamin K2, in bacteria) , phylloquinone (vitamin K1 in plants) , and many plant pigments.The coenzyme A group is subsequently removed from the product by EC 3.1.2.28, 1,4-Dihydroxy-2-naphthoyl-CoA hydrolase.

HY-B2156S1

Menaquinone-4-13C6 vitamin K2(MK-4)-¹³C₆; Menaquinone K4-¹³C₆	Isotope-Labeled Compounds Endogenous Metabolite	Cancer
Menaquinone-4- ¹³C₆ is the ¹³C-labeled Menaquinone-4. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.

Cat. No.	Nombre del producto	Category	Target	Chemical Structure

HY-B0332

Menadione 25+ Cited Publications vitamin K3	Quinones Structural Classification Microorganisms Classification of Application Fields Other Diseases Endogenous metabolite Naphthalene Quinones Disease Research Fields Source Classification	Environmental Pollutants Endogenous Metabolite
Menadione is a naphthoquinone that is converted into active vitamin K2 in the body. Menadione is a potential anticancer agent and radiosensitizer .

HY-W011474

Geranylgeraniol	Productos naturales Microorganisms	NF-κB
Geranylgeraniol is an orally acitve vitamin K₂ sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model .

HY-B2156

Menaquinone-4 5+ Cited Publications vitamin K2(MK-4); Menaquinone K4	Quinones Microorganisms other families Classification of Application Fields Plants Endogenous metabolite Naphthalene Quinones Disease Research Fields Source Classification Cancer	Endogenous Metabolite
Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.

HY-109569

Vitamin K2	Other Terpenoids Structural Classification Classification of Application Fields Terpenoids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Autophagy Apoptosis Interleukin Related
Vitamin K2 is an orally active proliferation inhibitor. Vitamin K2 induces Autophagy and Apoptosis. Vitamin K2 reduces the levels of proinflammatory cytokines (such as IL-1β, TNF-α, and IL-6). Vitamin K2 inhibits cell growth in leukemia cells. Vitamin K2 can be used for the research of involutional osteoporosis, non-alcoholic fatty liver disease, ulcerative colitis, acute myeloid leukemia, myelodysplastic syndromes, and hepatocellular carcinoma .

HY-B0332R

Menadione (Standard) vitamin K3 (Standard)	Quinones Structural Classification Microorganisms Endogenous metabolite Naphthalene Quinones Source Classification	Reference Standards Endogenous Metabolite
Menadione (Standard) is the analytical standard of Menadione. This product is intended for research and analytical applications. Menadione is a naphthoquinone that is converted into active vitamin K2 in the body. Menadione is a potential anticancer agent and radiosensitizer .

HY-W011474R

Geranylgeraniol (Standard)	Structural Classification Productos naturales Microorganisms	Reference Standards NF-κB
Geranylgeraniol (Standard) is the analytical standard of Geranylgeraniol. This product is intended for research and analytical applications. Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model [4].

HY-B2156R

Menaquinone-4 (Standard) vitamin K2(MK-4) (Standard); Menaquinone K4 (Standard)	Quinones Structural Classification Microorganisms other families Plants Endogenous metabolite Naphthalene Quinones Source Classification	Reference Standards Endogenous Metabolite
Menaquinone-4 (Standard) is the analytical standard of Menaquinone-4. This product is intended for research and analytical applications. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.

HY-134537

Vitamin K2(5)	Quinones Structural Classification Handroanthus impetiginosus (Mart. ex DC.) Mattos Bignoniaceae Plants Naphthalene Quinones Source Classification	Drug Derivative
Vitamin K2 (5) (Compound 1) is a prenylogue of the Vitamin K2 (HY-109569) series that can be found in the heartwood of Tabebuia avellanedae .

Cat. No.	Nombre del producto	Chemical Structure

HY-B2156S

Menaquinone-4-d7
Menaquinone-4-d₇ (Vitamin K2(MK-4)-d7) is the deuterium labeled Menaquinone-4. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.

HY-B0332S

Menadione-d3
Menadione-d₃ is the deuterium labeled Menadione. Menadione, a synthetic naphthoquinone, can be converted to active vitamin K2 in vivo.

HY-112499S

Menaquinone-7-d7
Menaquinone-7-d₇ is the deuterium labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors . Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins . Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS) .

Menaquinone-7-d7

Menaquinone-7-d₇ is the deuterium labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors . Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins . Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS) .

HY-112499S1

Menaquinone-7-13C6
Menaquinone-7- ¹³C₆ is the ¹³C-labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors . Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins . Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS) .

Menaquinone-7-13C6

Menaquinone-7- ¹³C₆ is the ¹³C-labeled Menaquinone-7. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors . Menaquinone-7 (Vitamin K2-7) is identified as the most bioactive cofactor for the carboxylation reaction of Gla-proteins . Supplementation with Menaquinone-7 (Vitamin K2-7) is a pharmacological option for activating matrix Gla protein and intervening in the progression of calcific aortic valve stenosis (CAVS) .

HY-W769519

Vitamin K2(5)-D7
Vitamin K2(5)-d₇ is the deuterium labeled Vitamin K2(5) (HY-134537).

HY-W011474S

Geranylgeraniol-d5
Geranylgeraniol-d₅ is the deuterium labeled Geranylgeraniol (HY-W011474). Geranylgeraniol is an orally acitve vitamin K2 sub-type, an intermediate of the mevalonate pathway. Geranylgeraniol targets NF-kB signaling pathway and could alleviate LPS-induced microglial inflammation in animal model .

HY-B2156S1

Menaquinone-4-13C6
Menaquinone-4- ¹³C₆ is the ¹³C-labeled Menaquinone-4. Menaquinone-4 is a vitamin K, used as a hemostatic agent, and also a adjunctive therapy for the pain of osteoporosis.

Cat. No.	Nombre del producto		Classification

HY-177831

*Liposomal Vitamin* K2**		Liposome
Liposomal Vitamin K2 is a specialized delivery system that encapsulates vitamin K2 within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of vitamin K2. Vitamin K2 (menaquinone-7) is?a fat-soluble nut

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