11032-49-8
11032-49-8
Chemical Structure
Biological Activity: Vitamin K2 is an orally active proliferation inhibitor. Vitamin K2 induces Autophagy and Apoptosis. Vitamin K2 reduces the levels of proinflammatory cytokines (such as IL-1β, TNF-α, and IL-6). Vitamin K2 inhibits cell growth in leukemia cells. Vitamin K2 can be used for the research of involutional osteoporosis, non-alcoholic fatty liver disease, ulcerative colitis, acute myeloid leukemia, myelodysplastic syndromes, and hepatocellular carcinoma[1][2][3][4].
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Vitamin K2 | Vitamin K2 is an orally active proliferation inhibitor. Vitamin K2 induces Autophagy and Apoptosis. Vitamin K2 reduces the levels of proinflammatory cytokines (such as IL-1β, TNF-α, and IL-6). Vitamin K2 inhibits cell growth in leukemia cells. Vitamin K2 can be used for the research of involutional osteoporosis, non-alcoholic fatty liver disease, ulcerative colitis, acute myeloid leukemia, myelodysplastic syndromes, and hepatocellular carcinoma. | |||||||||||||||||||||
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References
- [1]. Akedo Y, et al. Vitamin K2 modulates proliferation and function of osteoblastic cells in vitro. Biochem Biophys Res Commun. 1992;187(2):814-820. [Content Brief]
- [2]. Zhao P, et al. Vitamin K2 protects mice against non-alcoholic fatty liver disease induced by high-fat diet. Sci Rep. 2024;14(1):3075. Published 2024 Feb 6. [Content Brief]
- [3]. Hu S, et al. Ameliorating Effects of Vitamin K2 on Dextran Sulfate Sodium-Induced Ulcerative Colitis in Mice. Int J Mol Sci. 2023;24(3):2986. Published 2023 Feb 3. [Content Brief]
- [4]. Yokoyama T, et al. Vitamin K2 induces autophagy and apoptosis simultaneously in leukemia cells. Autophagy. 2008;4(5):629-640. [Content Brief]
