41 Results for "

white mice

" in MedChemExpress (MCE) Product Catalog:
Products (41)

41 Results for "white mice" in MCE Product Catalog:

9
9 Publications Verification
Cat. No.: HY-B0227
CAS No.: 22071-15-4
Synonyms: RP-19583
Target:  

COX

Ketoprofen (RP-19583) is a non-steroidal anti-inflammatory agent. Ketoprofen can inhibits the activity of cyclooxygenase with IC50 values of 2 nM (COX-1) and 26 nM (COX-2). which is potential in the research of inflammation, immunology, and metabolic disease such as obesity .
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5
5 Cited Publications
Cat. No.: HY-W250978
CAS No.: 9006-59-1
Ovalbumins are the major proteins in egg white. Ovalbumins act as an allergen and inducer, and can be applied to mouse models of allergic diseases. Ovalbumins can induce allergic rhinitis in mice via sensitization and nasal challenge. Ovalbumins can be used to establish asthma models.
Ovalbumin, low endotoxin (HY-W250978A) is recommended for model establishment .
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2
2 Cited Publications
Cat. No.: HY-112726
CAS No.: 1478364-68-9
Purity:  98.79%
Synonyms: BI-1467335
Target:  

VAP-1 MMP

PXS-4728A is an orally active, selective VAP-1/SSAO inhibitor with an IC50 of 5 nM and a Ki of 175 nM. PXS-4728A inhibits the expression of MMP-9. It reduces cell rolling, adhesion and migration, decreases cell infiltration levels, pro-inflammatory cytokines, chemokines and collagen deposition, and improves pulmonary function. PXS-4728A reduces the formation and progression of atherosclerotic plaques, and decreases blood lipid and blood glucose levels as well as body weight gain. PXS-4728A can be used in research related to chronic obstructive pulmonary disease, cystic fibrosis, acute pulmonary inflammation, acute lung injury, bronchiolitis obliterans syndrome, rhinovirus-exacerbated asthma, sepsis, Klebsiella pneumoniae pulmonary infection and atherosclerosis .
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1
1 Cited Publications
Cat. No.: HY-A0022A
CAS No.: 63302-99-8
Synonyms: Azafen dihydrochloride monohydrate; Pipofezin dihydrochloride monohydrate; Pipofezine dihydrochloride monohydrate; Azaphenonxazine dihydrochloride monohydrate
Target:  

Serotonin Transporter

Research Areas:  

Neurological Disease

Azaphen (Pipofezin) dihydrochloride monohydrate is an orally active serotonin reuptake inhibitor. Azaphen dihydrochloride monohydrate potentiates sympathomimetic compound effects. Azaphen dihydrochloride monohydrate can be used for the research of depressive states .
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Cat. No.: HY-W250978A
CAS No.: 9006-59-1
Ovalbumin, low endotoxin are the major proteins in egg white. Ovalbumin, low endotoxin act as an allergen and inducer, and can be applied to mouse models of allergic diseases. Ovalbumin, low endotoxin can induce allergic rhinitis in mice via sensitization and nasal challenge. Ovalbumin, low endotoxin can be used to establish asthma models .
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Cat. No.: HY-Y0095
CAS No.: 107-36-8
Synonyms: 2-Hydroxyethanesulfonic acid
Isethionic acid (2-Hydroxyethanesulfonic acid) is an endogenous mammalian Taurine (HY-B0351) metabolite. Isethionic acid forms covalent ester linkages with cholic acid. It acts as a larval settlement inhibitor for Balanus amphitrite with larval toxicity. Isethionic acid enables the low-temperature synthesis of highly hygroscopic water-soluble sulfonates, and its acylated derivatives serve as acidic wetting solubilizers. It is used in studies related to hepatic bile acid metabolism, biological control and organic synthesis .
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Cat. No.: HY-W012974
CAS No.: 144-90-1
Synonyms: β-Aminoisobutyric acid; BAIBA
3-Aminoisobutyric acid (β-Aminoisobutyric acid) has anti-inflammatory and antioxidant effects. 3-Aminoisobutyric acid increases the expression of brown adipocyte-specific genes in white adipose tissue and fatty acid β-oxidation in hepatocytes. 3-Aminoisobutyric acid attenuates insulin resistance and inflammation induced by palmitate or a high fat diet via an AMPK-PPARδ-dependent pathway in mice. 3-Aminoisobutyric acid is a catabolic metabolite of thymine and valine in skeletal muscle .
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Cat. No.: HY-126573
CAS No.: 538-24-9
Purity:  ≥98.0%
Trilaurin is an orally active triglyceride. Trilaurin inhibits DMBA-induced, croton oil-promoted skin tumor formation in Swiss Webster mice. Trilaurin increases plasma high-density lipoprotein cholesterol and apolipoprotein A-I concentrations. Trilaurin is used as an occlusive skin conditioning agent and/or non-aqueous thickener in cosmetics .
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Cat. No.: HY-P991736
Anti-IL11 Antibody (X203, Mouse IgG) is an antibody targeting IL-11. Anti-IL11 Antibody (X203, Mouse IgG) inhibits IL-11-mediated activation of the ERK-mTORC1 axis, inactivation of LKB1-AMPK, and pro-senescence pathways. Anti-IL11 Antibody (X203, Mouse IgG) alleviates age-related metabolic decline, improves muscle function, reduces tissue fibrosis, decreases the expression of senescence markers, and maintains telomere length and mtDNA copy number. Anti-IL11 Antibody (X203, Mouse IgG) restores browning of white adipose tissue, upregulates thermogenic and mitochondrial biogenesis gene programs, reduces lipid droplet size, and decreases immune cell infiltration in visceral white adipose tissue. Anti-IL11 Antibody (X203, Mouse IgG) extends the median lifespan of mice and reduces the incidence of age-related tumors. Anti-IL11 Antibody (X203, Mouse IgG) can be used in the research of age-related metabolic decline, sarcopenia and age-related cancers .
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Cat. No.: HY-W019151
CAS No.: 569-31-3
Meconine is the urinary metabolite of Noscapine (HY-13716) and also a phase I metabolite of Bromonoscapine. Meconine can serve as a complementary biomarker in addition to opioid metabolites .
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Cat. No.: HY-P3538
CAS No.: 9015-71-8
Synonyms: CRH (Sheep)
Target:  

Peptides

Research Areas:  

Neurological Disease

Corticotropin-releasing factor (CRH) (Sheep) is a brain-penetrant hypothalamic releasing factor and a peptide hormone with analgesic and arousal-inducing activity. Corticotropin-releasing factor (Sheep) mediates stress effects, including stress-induced analgesia. Corticotropin-releasing factor (Sheep) increases wakefulness, reduces slow wave sleep, alters EEG frequency content, stimulates ACTH and β-endorphin release, activates locomotor activity. Corticotropin-releasing factor (Sheep) can be used for the research of neurological disease .
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Cat. No.: HY-W009417
CAS No.: 77-54-3
Cedryl acetate is an orally active α-glucosidase inhibitor with an IC50 of 94 μM against yeast α-glucosidase. Cedryl acetate reduces high-fat diet-induced body weight gain, visceral fat pad weight, adipocyte hypertrophy, hepatic lipid accumulation, glucose intolerance, insulin resistance and gluconeogenesis. Cedryl acetate can be used in the research of obesity and obesity-related metabolic syndrome .
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Cat. No.: HY-Y1173
CAS No.: 1562-00-1
Synonyms: 2-Hydroxyethanesulfonic acid sodium; Sodium isethionate
Isethionic acid sodium salt (2-Hydroxyethanesulfonic acid sodium; Sodium isethionate) is an endogenous mammalian Taurine (HY-B0351) metabolite. Isethionic acid sodium salt forms covalent ester linkages with cholic acid. It acts as a larval settlement inhibitor for Balanus amphitrite with larval toxicity. Isethionic acid sodium salt enables the low-temperature synthesis of highly hygroscopic water-soluble sulfonates, and its acylated derivatives serve as acidic wetting solubilizers. It is used in studies related to hepatic bile acid metabolism, biological control and organic synthesis .
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Cat. No.: HY-W012865
CAS No.: 80-69-3
Tartronic acid, a dicarboxylic acid derive, is an inhibitor of the transformation of carbohydrates into fat under fat-deficient diet conditions. Tartronic acid promotes 3T3-L1 adipocyte differentiation by increasing the protein expression of FABP-4, PPARγ and SREBP-1. Tartronic acid promotes de novo lipogenesis and inhibits CPT-1β by upregulating acetyl-CoA and malonyl-CoA. Tartronic acid promotes weight gain and induces adipocyte hypertrophy in epididymal white adipose tissue and lipid accumulation in the livers of high-fat diet induced obese mice. Tartronic acid can be used for lipid metabolic disease research .
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Cat. No.: HY-W134301
CAS No.: 10043-67-1
Synonyms: Potassium alum
Research Areas:  

Infection

Aluminum potassium sulfate (Potassium alum) is an egg white adjuvant. Aluminum potassium sulfate acts as a mordant to help dyes bind to tissue components, enhancing the staining effect and stability during staining. Aluminum potassium sulfate can induce allergic reactions in mice. Aluminum potassium sulfate can be used in research for bacterial and tissue staining .
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Cat. No.: HY-B2241A
CAS No.: 7784-24-9
Synonyms: Aluminum potassium sulfate dodecahydrate, for cell culture
Potassiumalum, for cell culture (Aluminum potassium sulfate dodecahydrate, for cell culture) is an egg white adjuvant. Potassiumalum, for cell culture acts as a mordant to help dyes bind to tissue components, enhancing the staining effect and stability during staining. Potassiumalum, for cell culture can induce allergic reactions in mice. Potassium alum, for cell culture can be used in research for bacterial and tissue staining .
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Cat. No.: HY-P10586A
Synonyms: MALP-2 TFA
Macrophage-activating lipopeptide 2 TFA is an agonist of Toll like receptors TLR-2/TLR-6. Macrophage-activating lipopeptide-2 enhances endothelial nitric oxide synthase (eNOS) phosphorylation and endothelial cell release of NO, thereby improving vasodilation. Macrophage-activating lipopeptide-2 enhances endothelial adhesion of white blood cells and improve perfusion recovery and collateral growth in the hind limbs of hypercholesterolemic Apoe deficient mice undergoing experimental femoral artery ligation (FAL) .
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Cat. No.: HY-W019151R
CAS No.: 569-31-3
Meconine (Standard) is the analytical standard of Meconine (HY-W019151). This product is intended for research and analytical applications. Meconine is the urinary metabolite of Noscapine (HY-13716) and also a phase I metabolite of Bromonoscapine. Meconine can serve as a complementary biomarker in addition to opioid metabolites .
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Cat. No.: HY-B1265
CAS No.: 57524-89-7
Synonyms: Cortisol 17-valerate
Hydrocortisone 17-valerate (Cortisol 17-valerate) is a 17α-ester derivative of Hydrocortisone (HY-N0583), an endogenous glucocorticoid with anti-inflammatory activity. Hydrocortisone 17-valerate can be used for research on skin inflammation .
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Cat. No.: HY-A0022
CAS No.: 24853-80-3
Synonyms: Azafen; Pipofezin hydrochloride; Pipofezine hydrochloride
Category:  

Natural Products Animals

Target:  

Serotonin Transporter

Azaphen (Pipofezin) is an orally active serotonin reuptake inhibitor. Azaphen potentiates sympathomimetic compound effects. Azaphen can be used for the research of depressive states .
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