24853-80-3

Azaphen Chemical Structure
24853-80-3

Chemical Structure

Azaphen

Synonym(s): Azafen; Pipofezin hydrochloride; Pipofezine hydrochloride

  • CAS No.: 24853-80-3
  • Formula:C16H21Cl2N5O
  • Molecular Weight:370.28

IUPAC Name: 5-methyl-3-(4-methylpiperazin-1-yl)-5H-benzo[b]pyridazino[4,3-e][1,4]oxazine dihydrochloride

InChIKey: ZZVWCKAYZSAUKR-UHFFFAOYSA-N

SMILES: [H]Cl.[H]Cl.CN1C2=CC=CC=C2OC3=C1C=C(N4CCN(C)CC4)N=N3

Biological Activity: Azaphen (Azafen) is an orally active tricyclic antidepressant that inhibits the reuptake of serotonin and monoamines, regulates the 5-HT2c receptor, and exerts sedative, antidepressant and anxiolytic effects. Azaphen increases the bioavailability of serotonin in the synaptic cleft, does not block muscarinic receptors or affect monoamine oxidase activity, and binds to the human serotonin transporter via salt bridges, π-stacking, π-cation and hydrophobic interactions. Azaphen can be used in studies related to depression[1][2][3].

Cat. No. Product Name Purity Description Pricing
HY-A0022
Azaphen Azaphen (Azafen) is an orally active tricyclic antidepressant that inhibits the reuptake of serotonin and monoamines, regulates the 5-HT2c receptor, and exerts sedative, antidepressant and anxiolytic effects. Azaphen increases the bioavailability of serotonin in the synaptic cleft, does not block muscarinic receptors or affect monoamine oxidase activity, and binds to the human serotonin transporter via salt bridges, π-stacking, π-cation and hydrophobic interactions. Azaphen can be used in studies related to depression.
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