SIRT5 inhibitor 5
SIRT5 inhibitor 5 is a potent SIRT5 inhibitor with an IC50 value of 0.21 µM. SIRT5 inhibitor 5 does not occupy the NNAD+ -binding pocket and acts as a substrate-competitive inhibitor.
For research use only. We do not sell to patients.
- CAS No.: 2883730-60-5
- Formula: C21H14ClN3O3S
- Molecular Weight:423.87
-
Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
SIRT5 0.21 μM (IC50) |
In Vitro
SIRT5 inhibitor 5 (compound 47) (0-10 µM) shows no significant change in the inhibitory activity in different concentrations of NAD+ (50, 100, 200, 400, 800 µM) and decreases the inhibitory activity in the presence of increased concentrations of Ac-K(Suc)-AMC (10, 30, 90, 270 µM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2883730-60-5
-
Appearance Solid
-
Molecular Weight 423.87
-
Formula C21H14ClN3O3S
-
Color Off-white to light brown
-
SMILES
CC1=NN(C(/C1=C/C2=CC=C(C=C2)C(O)=O)=O)C3=NC(C4=CC=C(C=C4)Cl)=CS3
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
-
Data Sheet (267 KB)
-
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SIRT5 inhibitor 5 Related Classifications
HY-152214 Related Classifications
Powered by Bioz