SIRT5 inhibitor 5
SIRT5 inhibitor 5 is a potent SIRT5 inhibitor with an IC50 value of 0.21 µM. SIRT5 inhibitor 5 does not occupy the NNAD+ -binding pocket and acts as a substrate-competitive inhibitor.
For research use only. We do not sell to patients.
- CAS No.: 2883730-60-5
- Formula: C21H14ClN3O3S
- Molecular Weight:423.87
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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SIRT5 0.21 μM (IC50) |
SIRT5 inhibitor 5 (compound 47) (0-10 µM) shows no significant change in the inhibitory activity in different concentrations of NAD+ (50, 100, 200, 400, 800 µM) and decreases the inhibitory activity in the presence of increased concentrations of Ac-K(Suc)-AMC (10, 30, 90, 270 µM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2883730-60-5
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Molecular Weight 423.87
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Formula C21H14ClN3O3S
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SMILES
CC1=NN(C(/C1=C/C2=CC=C(C=C2)C(O)=O)=O)C3=NC(C4=CC=C(C=C4)Cl)=CS3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SIRT5 inhibitor 5 Related Classifications
HY-152214 Related Classifications
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