2883730-60-5
2883730-60-5
Chemical Structure
SIRT5 inhibitor 5
- CAS No.: 2883730-60-5
- Formula:C21H14ClN3O3S
- Molecular Weight:423.87
IUPAC Name: (E)-4-((1-(4-(4-chlorophenyl)thiazol-2-yl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)methyl)benzoic acid
InChIKey: BASVBEFRHZKYIH-LICLKQGHSA-N
SMILES: CC1=NN(C(/C1=C/C2=CC=C(C=C2)C(O)=O)=O)C3=NC(C4=CC=C(C=C4)Cl)=CS3
Biological Activity: SIRT5 inhibitor 5 is a potent SIRT5 inhibitor with an IC50 value of 0.21 µM. SIRT5 inhibitor 5 does not occupy the NNAD+ -binding pocket and acts as a substrate-competitive inhibitor[1].
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SIRT5 inhibitor 5 | SIRT5 inhibitor 5 is a potent SIRT5 inhibitor with an IC50 value of 0.21 µM. SIRT5 inhibitor 5 does not occupy the NNAD+ -binding pocket and acts as a substrate-competitive inhibitor. | |||||||||||||||||||||
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References
Keywords
