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  2. Bacterial Antibiotic Isotope-Labeled Compounds
  3. Sulfameter-d4

Sulfameter-d4  (Synonyms: Sulfametoxydiazine-d4; 5-Methoxysulfadiazine-d4; NSC 683528-d4)

Art. -Nr.: HY-B0213S Reinheit: 99.58%
Handling Instructions Technical Support

Sulfameter-d4 (Sulfametoxydiazine-d4) is the deuterium labeled Sulfameter (HY-B0213). Sulfameter (Sulfametoxydiazine) is an orally active long-acting sulfonamide antibiotic. Sulfameter is active against both Gram-positive and Gram-negative bacteria. Sulfameter can be used for the research of diseases such as respiratory and urinary tract infections.

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Sulfameter-d<sub>4</sub>

Sulfameter-d4 Chemische Struktur

CAS. Nr. : 1189483-96-2

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1 mg Angebot einholen 2-4 weeks 2-4 weeks 2-4 weeks 2-4 weeks
5 mg   Angebot einholen  
10 mg   Angebot einholen  
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Beschreibung

Sulfameter-d4 (Sulfametoxydiazine-d4) is the deuterium labeled Sulfameter (HY-B0213)[1]. Sulfameter (Sulfametoxydiazine) is an orally active long-acting sulfonamide antibiotic. Sulfameter is active against both Gram-positive and Gram-negative bacteria. Sulfameter can be used for the research of diseases such as respiratory and urinary tract infections[1].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molekulargewicht

284.33

Formel

C11H8D4N4O3S

CAS. Nr.
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

O=S(C1=C([2H])C([2H])=C(N)C([2H])=C1[2H])(NC2=NC=C(OC)C=N2)=O

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro: 

DMSO : 50 mg/mL (175.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5170 mL 17.5852 mL 35.1704 mL
5 mM 0.7034 mL 3.5170 mL 7.0341 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molaritätsrechner

  • Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Reinheit & Dokumentation
Verweise

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5170 mL 17.5852 mL 35.1704 mL 87.9260 mL
5 mM 0.7034 mL 3.5170 mL 7.0341 mL 17.5852 mL
10 mM 0.3517 mL 1.7585 mL 3.5170 mL 8.7926 mL
15 mM 0.2345 mL 1.1723 mL 2.3447 mL 5.8617 mL
20 mM 0.1759 mL 0.8793 mL 1.7585 mL 4.3963 mL
25 mM 0.1407 mL 0.7034 mL 1.4068 mL 3.5170 mL
30 mM 0.1172 mL 0.5862 mL 1.1723 mL 2.9309 mL
40 mM 0.0879 mL 0.4396 mL 0.8793 mL 2.1982 mL
50 mM 0.0703 mL 0.3517 mL 0.7034 mL 1.7585 mL
60 mM 0.0586 mL 0.2931 mL 0.5862 mL 1.4654 mL
80 mM 0.0440 mL 0.2198 mL 0.4396 mL 1.0991 mL
100 mM 0.0352 mL 0.1759 mL 0.3517 mL 0.8793 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Sulfameter-d4
Art. -Nr.:
HY-B0213S
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