651-06-9
Chemical Structure
Sulfameter
Synonym(s): Sulfametoxydiazine; 5-Methoxysulfadiazine; NSC 683528
- CAS No.: 651-06-9
- Formula:C11H12N4O3S
- Molecular Weight:280.30
IUPAC Name: 4-amino-N-(5-methoxypyrimidin-2-yl)benzenesulfonamide
InChIKey: GPTONYMQFTZPKC-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(N)C=C1)(NC2=NC=C(OC)C=N2)=O
Biological Activity: Sulfameter (Sulfametoxydiazine) is an orally active long-acting sulfonamide antibiotic. Sulfameter is active against both Gram-positive and Gram-negative bacteria. Sulfameter can be used for the research of diseases such as respiratory and urinary tract infections[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Sulfameter | 99.94% | Sulfameter (Sulfametoxydiazine) is an orally active long-acting sulfonamide antibiotic. Sulfameter is active against both Gram-positive and Gram-negative bacteria. Sulfameter can be used for the research of diseases such as respiratory and urinary tract infections. | ||||||||||||||||||||
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Sulfameter (Standard) | ≥98% | Sulfameter (Standard) (Sulfametoxydiazine (Standard)) is the analytical standard of Sulfameter (HY-B0213). This product is intended for research and analytical applications. Sulfameter (Sulfametoxydiazine) is an orally active long-acting sulfonamide antibiotic. Sulfameter is active against both Gram-positive and Gram-negative bacteria. Sulfameter can be used for the research of diseases such as respiratory and urinary tract infections. | ||||||||||||||||||||
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Sulfameter-d4 | 99.58% | Sulfameter-d4 (Sulfametoxydiazine-d4) is the deuterium labeled Sulfameter (HY-B0213). Sulfameter (Sulfametoxydiazine) is an orally active long-acting sulfonamide antibiotic. Sulfameter is active against both Gram-positive and Gram-negative bacteria. Sulfameter can be used for the research of diseases such as respiratory and urinary tract infections. | ||||||||||||||||||||
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Sulfameter-13C6 | Sulfameter-13C6 (Sulfametoxydiazine-13C6) is the 13C6 labeled Sulfameter (HY-B0213). Sulfameter (Sulfametoxydiazine) is an orally active long-acting sulfonamide antibiotic. Sulfameter is active against both Gram-positive and Gram-negative bacteria. Sulfameter can be used for the research of diseases such as respiratory and urinary tract infections. | |||||||||||||||||||||
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Glymidine | Glymidine (Glidiazine) is a hypoglycaemic agent. Glymidine is a lipid soluble sulphapyrimidine derivative. Glymidine appears to stimulate insulin release from pancreas. Glymidine is a possible alternative to the sulphonylureas and biguanides for the research of diabetes mellitus. | |||||||||||||||||||||
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Sulfaperin | 99.87% | Sulfaperin (Methylsulfadiazin) is an antibacterial agent. | ||||||||||||||||||||
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Sulfamethazine (Standard) | 99.46% | Sulfamethazine (Standard) is the analytical standard of Sulfamethazine (HY-B0035). This product is intended for research and analytical applications. Sulfamethazine (Sulfadimidine) is a brain-penetrant sulfonamide antibiotic. Sulfamethazine inhibits bacterial growth by blocking the synthesis of folic acid. Sulfamethazine can be used for research on bacterial infections. | ||||||||||||||||||||
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Sulfamethazine-13C6 | 98.00% | Sulfamethazine-13C6 is a 13C-labeled Sulfamethazine (HY-A0178). Sulfamethazine (Sulfadimidine) is a brain-penetrant sulfonamide antibiotic. Sulfamethazine inhibits bacterial growth by blocking the synthesis of folic acid. Sulfamethazine can be used for research on bacterial infections. | ||||||||||||||||||||
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Sulfadiazine (Standard) | 99.84% | Sulfadiazine (Standard) is the analytical standard of Sulfadiazine (HY-B0273). This product is intended for research and analytical applications. Sulfadiazine is an orally active sulfonamide antibiotic. Sulfadiazine competitively inhibits p-aminobenzoic acid in the folic-acid-metabolism cycle, inhibiting multiplication of most Gram-positive and many Gram-negative bacteria. Sulfadiazine persists in soil long-term, and exerts selective pressure for sulfonamide-resistant microbial populations. Sulfadiazine targets Toxoplasma gondii DHPS enzyme. Sulfadiazine can be used for the research of congenital toxoplasmosis and bacterial infection. | ||||||||||||||||||||
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Sulfadiazine-13C6 | 99.18% | Sulfadiazine-13C6 is a labeled Sulfadiazine (HY-B0273). Sulfadiazine is an orally active sulfonamide antibiotic. Sulfadiazine competitively inhibits p-aminobenzoic acid in the folic-acid-metabolism cycle, inhibiting multiplication of most Gram-positive and many Gram-negative bacteria. Sulfadiazine persists in soil long-term, and exerts selective pressure for sulfonamide-resistant microbial populations. Sulfadiazine targets Toxoplasma gondii DHPS enzyme. Sulfadiazine can be used for the research of congenital toxoplasmosis and bacterial infection. | ||||||||||||||||||||
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Sulfamerazine (Standard) | 99.72% | Sulfamerazine (Standard) is the analytical standard of Sulfamerazine. This product is intended for research and analytical applications. Sulfamerazine (RP2632) is a brain-penetrant and orally active sulfonamide antibiotic and α-synuclein inhibitor with human α-synuclein KD of 352 μM. Sulfamerazine inhibits the synthesis of dihydrofolate by bacteria, thereby inhibiting bacterial growth. Sulfamerazine inhibits α-synuclein fibrillation, reduces α-synuclein aggregation-associated toxicity and α-synuclein aggregate accumulation. Sulfamerazine can be used for the research of Parkinson’s disease and bacterial infection. | ||||||||||||||||||||
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Sulfamerazine-13C6 | 99.11% | Sulfamerazine-13C6 (RP2632-13C6) is 13C labeled Sulfamerazine (HY-B0512). Sulfamerazine (RP2632) is a brain-penetrant and orally active sulfonamide antibiotic and α-synuclein inhibitor with human α-synuclein KD of 352 μM. Sulfamerazine inhibits the synthesis of dihydrofolate by bacteria, thereby inhibiting bacterial growth. Sulfamerazine inhibits α-synuclein fibrillation, reduces α-synuclein aggregation-associated toxicity and α-synuclein aggregate accumulation. Sulfamerazine can be used for the research of Parkinson’s disease and bacterial infection. | ||||||||||||||||||||
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Sulfamonomethoxine | 98.0% | Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity. | ||||||||||||||||||||
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Sulfamonomethoxine-13C6 | Sulfamonomethoxine-13C6 is the 13C6 labeled Sulfamonomethoxine (HY-B0946). Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity. | |||||||||||||||||||||
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References
- [1]. Douglas H.Nakahata, et al. Crystal structure, spectroscopic characterization and antibacterial activities of a silver complex with sulfameter. Journal of Molecular Structure. Volume 1125, 5 December 2016, Pages 609-615
- [2]. Seneca H. Sulfameter in clinical medicine. J Am Geriatr Soc. 1970 Jul;18(7):539-45. [Content Brief]