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Cat. No.: HY-119781

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Kaitocephalin

(Synonyms: PF1191)

Kaitocephalin (PF1191) is an ionotropic glutamate receptor (NMDAR) antagonist with K_i values of 7.8, 590, and 14000 nM for NMDAR, AMPAR, and KAR, respectively. Kaitocephalin protects neurons by inhibiting excitotoxicity, exhibiting neuroprotective effects. Kaitocephalin can be used in research on neurological diseases such as Alzheimer's disease.

For research use only. We do not sell to patients.

CAS No.: 198710-92-8
Formula: C₁₈H₂₁Cl₂N₃O₉
Molecular Weight:494.28

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Kaitocephalin Chemical Structure

CAS No.: 198710-92-8

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All iGluR Isoforms :

Chemical Information

CAS No. 198710-92-8
Molecular Weight 494.28
Formula C₁₈H₂₁Cl₂N₃O₉
SMILES

OC([C@H](N)[C@@H]([C@@]1(N[C@@H](C[C@@H](C(O)=O)NC(C2=CC(Cl)=C(O)C(Cl)=C2)=O)CC1)C(O)=O)O)=O
Synonyms

PF1191
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Yasuno Y, et al. Structure-activity relationship study at C9 position of kaitocephalin. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3543-6. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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Kaitocephalin

All iGluR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Kaitocephalin Related Classifications

HY-119781 Related Classifications