Z-VAD-FMK (Standard)

[1]. Slee EA, et al. Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD.FMK) inhibits apoptosis by blocking the processing of CPP32. Biochem J. 1996 Apr 1;315 ( Pt 1)(Pt 1):21-4. [Content Brief]

[2]. Martinet W, et al. Z-VAD-FMK-induced non-apoptotic cell death of macrophages: possibilities and limitations for atherosclerotic plaque stabilization. Autophagy. 2006 Oct-Dec;2(4):312-4. [Content Brief]

[3]. Pero ME, Zullo G, Esposito L, Iannuzzi A, Lombardi P, De Canditiis C, Neglia G, Gasparrini B. Inhibition of apoptosis by caspase inhibitor Z-VAD-FMK improves cryotolerance of in vitro derived bovine embryos. Theriogenology. 2018 Mar 1;108:127-135. [Content Brief]

[4]. Lawrence CP, Chow SC. Suppression of human T cell proliferation by the caspase inhibitors, Z-VAD-FMK and z-IETD-FMK is independent of their caspase inhibition properties. Toxicol Appl Pharmacol. 2012 Nov 15;265(1):103-12. [Content Brief]

[5]. Rajah T, Chow SC. The inhibition of human T cell proliferation by the caspase inhibitor Z-VAD-FMK is mediated through oxidative stress. Toxicol Appl Pharmacol. 2014 Jul 15;278(2):100-6. [Content Brief]

[6]. He M, et al. Effects of Z-VaD-Ala-Asp-Fluoromethyl Ketone (Z-VAD-FMK) and Acetyl-Asp-Glu-Val-Asp-Aldehyde(Ac-DEVD-CHO) on Inflammation and Mucus Secretion in Mice Exposed to Cigarette Smoke. Int J Chron Obstruct Pulmon Dis. 2023 Feb 5;18:69-78. [Content Brief]

[7]. Liu M, et al. Caspase inhibitor zVAD-fmk protects against acute pancreatitis-associated lung injury via inhibiting inflammation and apoptosis. Pancreatology. 2016 Sep-Oct;16(5):733-8. [Content Brief]

[8]. Liu HR, et al. Antiproliferative activity of the total saponin of Solanum lyratum Thunb in Hela cells by inducing apoptosis. Pharmazie. 2008 Nov;63(11):836-42. [Content Brief]

[9]. Davies CW, et al. The co-crystal structure of ubiquitin carboxy-terminal hydrolase L1 (UCHL1) with a tripeptide fluoromethyl ketone (Z-VAE(OMe)-FMK). Bioorg Med Chem Lett. 2012 Jun 15;22(12):3900-4. [Content Brief]