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Cat. No.: HY-146631S

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4-Hydroxy-17β-estradiol-1,2,16,16,17-d₅

Name: 4-Hydroxy-17β-estradiol-1,2,16,16,17-d5
Brand: MedChemExpress
SKU: HY-146631S
Price: 1620.00 USD
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1 Cited Publications

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Based on 1 publication(s) in Google Scholar

4-Hydroxy-17β-estradiol-1,2,16,16,17-d₅ is the deuterium labeled 4-Hydroxy-17β-estradiol-1,2,16,16,17.

For research use only. We do not sell to patients.

CAS No.: 221093-38-5
Formula: C₁₈H₁₉D₅O₃
Molecular Weight:293.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

4-Hydroxy-17β-estradiol-1,2,16,16,17-d₅ Chemical Structure

CAS No.: 221093-38-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Publications (1)
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Biological Activity

Description

4-Hydroxy-17β-estradiol-1,2,16,16,17-d₅ is the deuterium labeled 4-Hydroxy-17β-estradiol-1,2,16,16,17^[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS No. 221093-38-5
Unlabeled Cas 5976-61-4
Molecular Weight 293.41
Formula C₁₈H₁₉D₅O₃
SMILES

C[C@@]12[C@](CC([2H])([2H])[C@]2([2H])O)([H])[C@@]3([H])[C@@](CC1)([H])C4=C([2H])C([2H])=C(O)C(O)=C4CC3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Journal Impact Factor

Cell Rep Med

Profiling the metabolome of uterine fluid for early detection of ovarian cancer. [Abstract]

2023 Jun 20;4(6):101061. PMID: 37267943

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

4-Hydroxy-17β-estradiol-1,2,16,16,17-d₅

1 Cited Publications

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Biological Activity
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Publications (1)
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4-Hydroxy-17β-estradiol-1,2,16,16,17-d₅

Ethynyl Estradiol-d4

Estradiol-d3

Publications Citing Use of MedChemExpress (MCE) 4-Hydroxy-17β-estradiol-1,2,16,16,17-d₅

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4-Hydroxy-17β-estradiol-1,2,16,16,17-d5

Ethynyl Estradiol-d4

Estradiol-d3

Publications Citing Use of MedChemExpress (MCE) 4-Hydroxy-17β-estradiol-1,2,16,16,17-d5

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Chemical Information

Publications (1)

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4-Hydroxy-17β-estradiol-1,2,16,16,17-d5 Related Classifications

HY-146631S Related Classifications

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4-Hydroxy-17β-estradiol-1,2,16,16,17-d₅

Publications Citing Use of MedChemExpress (MCE) 4-Hydroxy-17β-estradiol-1,2,16,16,17-d₅

4-Hydroxy-17β-estradiol-1,2,16,16,17-d₅ Related Classifications