4-Hydroxysphinganine ceramide fatty acyl 2-hydroxylase

4-Hydroxysphinganine ceramide fatty acyl 2-hydroxylase (EC 1.14.18.6) is an oxidoreductase that can catalyze multiple reactions, including reaction 1: convert an N-(1,2 saturated acyl)-(4R)-hydroxysphinganine, 2 Fe(II)- [cytochrome b5], O2 and 2 H+ into an N-(2R-hydroxyacyl)- 4R-hydroxysphinganine, 2 Fe(III)-[cytochrome b5] and H2O; reaction 2: convert an N-(1,2 saturated very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base, 2 Fe(II)-[cytochrome b5], O2 and 2 H+ into an N-(2R-hydroxy-very-long-chain fatty acyl)-(R)-4-hydroxysphingoid base, 2 Fe(III)-[cytochrome b5] and H2O.

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