7-Amino-4-methylcoumarin-d4
7-Amino-4-methylcoumarin-d4 (Coumarin 120-d4) is the deuterium labeled 7-Amino-4-methylcoumarin (HY-D0027). 7-Amino-4-methylcoumarin belongs to the coumarin class, can be isolated from the endophytic fungus Xylaria sp. and has a broad spectrum of antibacterial activity. 7-Amino-4-methylcoumarin is also commonly used as an important laser dye that emits in the blue region, capable of analyzing glycoprotein monosaccharides and N-linked oligosaccharides, and is also utilized in tissue pathology analysis, enzyme activity measurement, and copper ion detection. The excitation wavelength and emission wavelength are 351 nm and 430 nm, respectively.
For research use only. We do not sell to patients.
- Formula: C10H5D4NO2
- Molecular Weight:179.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 26093-31-2
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Molecular Weight 179.21
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Formula C10H5D4NO2
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SMILES
O=C1C([2H])=C(C([2H])([2H])[2H])C2=CC=C(N)C=C2O1
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Synonyms
Coumarin 120-d4; AMC-d4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Żamojć K, et al. Fluorescence quenching of 7-amino-4-methylcoumarin by different TEMPO derivatives. Spectrochim Acta A Mol Biomol Spectrosc. 2015 Feb 5;136 Pt C:1875-80. [Content Brief]
[2]. Hiroshi Takase, et al. 7-Amino-4-methylcoumarin as a fluorescent substitute for Schiff's reagent: a new method that can be combined with hemalum and eosin staining on the same tissue section. Biotech Histochem. 2023 Jan;98(1):54-61. [Content Brief]
[4]. Xiaoyan Sun, wt al. A highly sensitive and selective ratiometric sensing platform based on 7-amino-4-methylcoumarin for naked-eye visual fluorescence sensing of Cu2. Spectrochim Acta A Mol Biomol Spectrosc. 2022 Feb 15;267(Pt 2):120627. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
7-Amino-4-methylcoumarin-d4 Related Classifications
HY-D0027S1 Related Classifications
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