2. Anti-infection Metabolic Enzyme/Protease
  3. HIV HIV Integrase
  4. LEDGIN6

LEDGIN6  (Synonyms: CX05168; CX04328)

Cat. No.: HY-10522 Purity: 98.80%
COA Handling Instructions

LEDGIN6 (CX05168) is a quinoline-based protein-protein interaction inhibitor of LEDGF/p75 and HIV integrase.

For research use only. We do not sell to patients.

LEDGIN6 Chemical Structure

LEDGIN6 Chemical Structure

CAS No. : 957890-42-5

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 385 In-stock
Solution
10 mM * 1 mL in DMSO USD 385 In-stock
Solid
5 mg USD 350 In-stock
10 mg USD 550 In-stock
50 mg USD 1600 In-stock
100 mg   Get quote  
200 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 4 publication(s) in Google Scholar

Other Forms of LEDGIN6:

LEDGIN6 Related Antibodies

Top Publications Citing Use of Products

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  • Purity & Documentation

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Description

LEDGIN6 (CX05168) is a quinoline-based protein-protein interaction inhibitor of LEDGF/p75 and HIV integrase[1].

Molecular Weight

353.84

Appearance

Solid

Formula

C21H20ClNO2
CAS No.
SMILES

ClC1=CC=C(N=C(C)C(C(CCC)C(O)=O)=C2C3=CC=CC=C3)C2=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (282.61 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8261 mL 14.1307 mL 28.2614 mL
5 mM 0.5652 mL 2.8261 mL 5.6523 mL
10 mM 0.2826 mL 1.4131 mL 2.8261 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (7.07 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 2.5 mg/mL (7.07 mM); Clear solution

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation
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LEDGIN6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

LEDGIN6957890-42-5CX05168 CX04328LEDGIN 6LEDGIN-6CX 05168CX-05168CX04328CX 04328CX-04328HIVHIV IntegraseHuman immunodeficiency virusInhibitorinhibitorinhibit

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