2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. O-Desmethylangolensin

O-Desmethylangolensin 

Cat. No.: HY-N4075 Purity: 98.70%
COA Handling Instructions

O-Desmethylangolensin is a metabolite of soy isoflavone, daidzein metabolized by gut microbiota. O-Desmethylangolensin possesses antioxidant activity.

For research use only. We do not sell to patients.

O-Desmethylangolensin Chemical Structure

O-Desmethylangolensin Chemical Structure

CAS No. : 21255-69-6

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 110 In-stock
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 110 In-stock
Solid
5 mg USD 100 In-stock
10 mg USD 150 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

O-Desmethylangolensin is a metabolite of soy isoflavone, daidzein metabolized by gut microbiota. O-Desmethylangolensin possesses antioxidant activity[1][2].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

O-Desmethylangolensin (O-DMA) inhibits the growth of HepG2 cells at higher doses (~30% decrease at 75 μM)[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

258.27

Appearance

Solid

Formula

C15H14O4
CAS No.
SMILES

CC(C1=CC=C(O)C=C1)C(C2=CC=C(O)C=C2O)=O
Structure Classification
Source

lactic acid bacteria and Bifidobacterium strains
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (241.99 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8719 mL 19.3596 mL 38.7192 mL
5 mM 0.7744 mL 3.8719 mL 7.7438 mL
10 mM 0.3872 mL 1.9360 mL 3.8719 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (8.05 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (8.05 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (8.05 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: 98.70%

COA (245 KB) HNMR (273 KB) LCMS (271 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

O-Desmethylangolensin21255-69-6Endogenous MetaboliteInhibitorinhibitorinhibit

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