Infection

Dictyopanine A is found in the strain of Dictylpanus sp. Hki 0181. The antibacterial spectrum is narrow, and it has moderate antibacterial activity only against some filamentous fungi and Gram-positive bacteria.

Micafungin (sodium) (Standard) is the analytical standard of Micafungin (sodium). This product is intended for research and analytical applications. Micafungin sodium (FK 463 sodium) is an antifungal agent which inhibits 1, 3-beta-D-glucan synthesis.

Ampicillin (trihydrate) (Standard) is the analytical standard of Ampicillin (trihydrate). This product is intended for research and analytical applications. Ampicillin trihydrate (D-(-)-α-Aminobenzylpenicillin trihydrate) is a broad-spectrum beta-lactam antibiotic against a variety of gram-positive and gram-negative bacteria.

Antibacterial agent 364 is an antibacterial agent. Antibacterial agent 364 inhibits the expression of the hrpY gene and downregulates the expression of prhG, phcA, prhA and prhR. Antibacterial agent 364 impairs the swimming motility of Ralstonia solanacearum, suppresses the T3SS-related regulatory network, and attenuates the virulence of Ralstonia solanacearum without inhibiting bacterial growth. Antibacterial agent 364 is applicable to studies related to plant infections.

(-)-cis-Myrtanol is a terpenoid compound derived from Artemisia dracunculus that exhibits effective antibacterial activity against harmful gut bacteria such as Bifidobacterium bifidum.

MMH409 is a selective HDAC8 inhibitor, with an IC₅₀ value of 23 nM and a K_d value of 3.5 nM against human HDAC8, and an IC₅₀ value of 11.64 μM against Schistosoma mansoni HDAC8. MMH409 reduces the viability of newly transformed schistosomula and adult worms of Schistosoma mansoni in vitro. MMH409 serves as a biological probe to investigate the pharmacological knockdown effect of HDAC8 in diseased cells. MMH409 can be used in studies related to neuroblastoma and schistosomiasis.

Bupirimate is a systemic fungicide that inhibits adenosine deaminase (ADA). Bupirimate is widely used in the cultivation of fruit trees, vegetables, flowers, and other crops to control powdery mildew.

Istamycin B has strong anti-Gram positive and negative bacteria actions.

Netilmicin sulfate (Standard) is the analytical standard of Netilmicin sulfate (HY-A0086). This product is intended for research and analytical applications. Netilmicin (Sch 20569) sulfate is a broad-spectrum semisynthetic aminoglycoside antibiotic. Netilmicin sulfate exhibits antibacterial activity against aminoglycoside-susceptible gram-negative strains and aminoglycoside-resistant strain, such as Escherichia coli, Pseudomonas aeruginosa, Proteus, Staphylococcus aureus, Streptococcus, Serratia, and Enterobacter, with MIC of 0.125-8 μg/mL.

RPX 7546 is a potent inhibitor of metallo-𝛽-lactamases (MBLs) with IC₅₀ values of 1.4 and 48 μM for IMP-1 and IMP-78, respectively. RPX 7546 has antibacterial activity.

(E)-Fagaramide is an amide and antifungal agent, can be found in the seeds and leaves of Piper tuberculatum, and inhibits growth of Cladosporium cladosporioides. (E)-Fagaramide can be used for the research of fungal infection (C. cladosporioides).

Kerriamycin A has anti-Gram-positive bacterial effect and can inhibits Ai's ascites cancer.

Himalomycin A is an anthraquinone antibiotic with strong activity against Staphylococcus aureus, Escherichia coli and Streptomyces vuridochromogenes.

Napyradiomycin B1 is an antibiotic with anti-Gram-positive bacteria and mycobacterial activity. Napyradiomycin B1 almost none to Gram-negative bacteria and fungi. IC₅₀ (μg/mL) of leukemia L-1210 cells is 2.2.

Octacosyl (E)-ferulate (Erythrinasinate B) (Compound 1) is an antiplasmodial compound. Octacosyl (E)-ferulate can be isolated from Erythrina.

WRS22, a derivative of Tirabrutinib (HY-15771), is a bacterial Tryptophanyl-tRNA synthetase (TrpRS) inhibitor with a K_d of 0.33 μM for EcTrpRS. WRS22 can be used for antibiotic resistance research.

(1-Aminopropyl) phosphonic acid is a phosphorus-containing amino acid fungicide with both protective and therapeutic effects, and it can be used in the research of fungus-related disorders.

Merulidial (Compound 1) is an antibiotic and cytotoxic agent with a sesquiterpene dialdehyde structure. Merulidial significantly inhibits the germination of spores and the hyphal growth of the wood-roting basidiomycete Heterobasidion annosum (H. annosum) and the saprophytic mould Cladosporium cucumerinum (C.cucumerinum). Merulidial also inhibits a variety of bacteria, algae and DNA synthesis of ECA cells. Merulidial shows a strong anticancer activity with IC₅₀ s of 20 and 10 μg/mL for ECA and L1210 cells, respectively .

Carbonic anhydrase-IN-36 (Compound 5p) is a MtCA 3 inhibitor with a K_i of 0.07 µM against MtCA 3. Carbonic anhydrase-IN-36 inhibits the β-class enzyme MtCA 3. Carbonic anhydrase-IN-36 demonstrates potent antimycobacterial activity, with an MIC of 8 µg/mL against Mtb. Carbonic anhydrase-IN-36 retains activity against Rifampicin (HY-B0272)-resistant M. tuberculosis.

Qianhucoumarin D, pyranocoumarin, is a nature product. Qianhucoumarin D can be isolated from the roots of Peucedanum praeruptorum. Qianhucoumarin D can be used for the research of inflammation and cancer.