Infection
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Infection Related Products (18883)
Related Products (18883)
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Antibodies (22)
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Tigemonam
0 ImagesCat. No.: HY-U00380CAS No.: 102507-71-1Tigemonam is an orally active monobactam antibiotic with a Ki of 0.86 μM against Enterobacter cloacae P99 β-lactamase and 50.8 μM against Escherichia coli TEM-1 β-lactamase. Tigemonam binds to penicillin-binding proteins 1a, 3, and 4, inhibits bacterial cell wall synthesis, and exhibits bactericidal activity against aerobic gram-negative bacteria including Enterobacteriaceae, Haemophilus influenzae, and Neisseria gonorrhoeae. Tigemonam resists hydrolysis by multiple β-lactamase enzymes, reduces bacterial load in systemic, pyelonephritic, lung, and thigh muscle infections in rodents, and shows minimal difference between minimum inhibitory and bactericidal concentrations. Tigemonam can be used for the research of gram-negative bacterial infections, acute pyelonephritis, lung infection, and thigh muscle infection.
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Antibacterial compound 1
0 ImagesCat. No.: HY-101819CAS No.: 232951-56-3Antibacterial compound 1 is a oxazolidinone extracted from patent WO1999037630A1 with antibacterial activities.
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Aliconazole
0 ImagesCat. No.: HY-U00311CAS No.: 63824-12-4Aliconazole is an antifungal imidazole derivative.
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0 ImagesCat. No.:Synonyms:-
Host:
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Application:
Human,
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Isotype:
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Reactivity:
,
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