Inflammation/Immunology

Embramine is a monoethanolamine used as an antihistamine and anticholinergic.

L-689502 is a potent inhibitor of HIV-l protease with an IC₅₀ of 1 nM.

CB1 antagonist 1 is an antagonist of CB1 receptor, used in the research of metabolic syndrome and obesity, neuroinflammatory disorders, cognitive disorders and psychosis, gastrointestinal disorders, and cardiovascular conditions.

Chymase-IN-2 is a chymase modulator which is useful in the treatment of inflammatory and serine protease mediated disorders.

Opigolix (ASP-1707) is a Gonadotropin-releasing hormone (GnRH) receptor antagonist, used for the research of endometriosis and rheumatoid arthritis.

3b,7a,17a-Trihydroxyandrost-5-ene is a immune modulator extracted from patent US20030060425.

Bronchospasmolytic agent 1, a synthetic flutropium bromide compound, acts as a bronchospasmolytic agent.

Tuftsin diacetate, a tetrapeptide, is a macrophage/microglial activator.

LTB4-IN-1 (Compound 6) is a leukotriene synthesis (LTB4) inhibitor with an IC₅₀ of 70 nM.

SC58451 is a potent and selective Cox-2 inhibitor.

TRPV antagonist 1 is a transient receptor potential vanilloid (TRPV) antagonist, with an IC₅₀ of < 250 nM.

CMI977 is a potent 5-Lipoxygenase (5-LO) inhibitor.

CI-949 is an allergic mediator release inhibitor, which inhibits histamine, leukotriene C₄/D₄ (LTC₄/LTD₄), and thromboxane B₂ (TXB₂) release with IC₅₀s of 11.4 μM, 0.5 μM and 0.1 μM, respectively.

Minocromil (FPL59360) is a new Anti-asthmatic agent.

Bunaprolast (U66858) is a potent inhibitor of LTB₄ production in human whole blood. Bunaprolast (U66858) also exhibits significant inhibition of lipoxygenase and TXB₂ release.

Aminochlorthenoxazin is an antipyretic and analgesic agent.

FRG-8701 is a new Histamine H₂-receptor antagonist with an IC₅₀ of ranging from 0.25 to 0.43 μM.

A2B receptor antagonist 1 is a potent A2B adenosine receptor antagonist extracted from patent WO 2009157938 A1 EXAMPLE 9B.

UP202-56 is an adenosine analogue, which is an adenosinergic agonist.

ZK-90055 hydrochloride is a β2 adrenergic receptor agonist.