1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W012634R
    Benzothiazole (Standard) 95-16-9
    Benzothiazole (Standard) is the analytical standard of Benzothiazole. This product is intended for research and analytical applications. Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent.
    Benzothiazole (Standard)
  • HY-W012999R
    Tiglic acid (Standard) 80-59-1 98%
    Tiglic acid (Standard) is the analytical standard of Tiglic acid (HY-W012999). This product is intended for research and analytical applications. Tiglic acid is a monocarboxylic unsaturated organic acid. Tiglic acid can be isolated from croton oil. Tiglic acid agonizes FFA2 and upregulates PYY expression. Tiglic acid derivatives have anti-inflammatory activity. Tiglic acid can be used in the research of obesity, diabetes, and inflammatory diseases.
    Tiglic acid (Standard)
  • HY-W013186S
    Lansoprazole sulfide-d4 1216682-38-0 99.0%
    Lansoprazole sulfide-d4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 μM intracellularly and 0.46 μM in broth.
    Lansoprazole sulfide-d4
  • HY-W013242R
    Gondoic acid (Standard) 5561-99-9
    Gondoic acid (Standard) is an analytical standard for Gondoic acid. This product is used for research and analytical applications. Gondoic acid (cis-11-Eicosenoic acid), a monounsaturated long-chain fatty acid, is contained in a variety of plant oils and nuts. Gondoic acid can exert anti-inflammatory activity by inhibiting the production of ROS and the PKCθ/ERK/STAT3 signaling pathway. Gondoic acid can be used as a raw material for medical supplies and a moisturizing ingredient in cosmetic creams.
    Gondoic acid (Standard)
  • HY-W013573R
    S-Allyl-L-cysteine (Standard) 21593-77-1
    S-Allyl-L-cysteine (Standard) is the analytical standard of S-Allyl-L-cysteine. This product is intended for research and analytical applications. S-Allyl-L-cysteine, one of the organosulfur compounds found in AGE, possess various biological effects including neurotrophic activity, anti-cancer activity, anti-inflammatory activity.
    S-Allyl-L-cysteine (Standard)
  • HY-W013724S
    Inosine-5'-diphosphate-15N4 dilithium 98%
    Inosine-5'-diphosphate-15N4 dilithium (IDP-15N4 dilithium) is 15N labeled Inosine-5'-diphosphate dilithium. Inosine-5'-diphosphate (IDP) is a decoy substrate of NM23-H2. Inosine-5'-diphosphate has a superior bond capacity on GDP-binding pocket of NM23-H2 (KD: 5.0 μM). Inosine-5'-diphosphate abrogates c-MYC transcription, induces apoptosis and G2/M cell cycle arrest by disrupting NM23-H2-Pu27-GQ interactions without affecting NM23-H2-mediated kinase properties. Inosine-5'-diphosphate has antihypoxic, antihyperthermic and antiarrhythmic activity and protects animals against the noxious effects of γ-irradiation. Inosine-5'-diphosphate can be used for cancers like Burkitt's lymphoma and cardiovascular diseases research.
    Inosine-5'-diphosphate-15N4 dilithium
  • HY-W013973S
    p-Terphenyl-d14 1718-51-0 99.8%
    p-Terphenyl-d14 is the deuterium labeled p-Terphenyl (HY-W013973). p-Terphenyl is a specialty material, and may be used in ionized radiation detectors, nonpolar laser dye, and single molecule optical probe of scanning near-field microscopy. p-Terphenyl can be used to synthesis p-Terphenyl derivatives, for the research of cancer and inflammatory diseases.
    p-Terphenyl-d14
  • HY-W014075R
    1-Hydroxypyrene (Standard) 5315-79-7 98%
    1-Hydroxypyrene (Standard) is the analytical standard of 1-Hydroxypyrene (HY-W014075). This product is intended for research and analytical applications. 1-Hydroxypyrene, a biomarker of exposure to polycyclic aromatic hydrocarbons (PAHs), is analyzed in urine samples. 1-Hydroxypyrene is the major biomarker of exposure to pyrenes. 1-Hydroxypyrene is the orally active agonist for aryl hydrocarbon receptor (AhR) and can lead to renal fibrosis.
    1-Hydroxypyrene (Standard)
  • HY-W014423R
    L-Histidine hydrochloride hydrate (Standard) 5934-29-2 98%
    L-Histidine hydrochloride hydrate (Standard) is the analytical standard of L-Histidine hydrochloride hydrate (HY-W014423). This product is intended for research and analytical applications. L-Histidine hydrochloride hydrate is an endogenous metabolite. L-Histidine hydrochloride hydrate scavenges hydroxyl radicals and singlet oxygen, regulate the absorption of zinc, copper and iron, exhibits anti-inflammatory and antioxidant activities. L-Histidine hydrochloride hydrate is blood brain barrier penetrable.
    L-Histidine hydrochloride hydrate (Standard)
  • HY-W014589S
    2,4-Di-tert-butylphenol-d19 1577233-55-6 98%
    2,4-Di-tert-butylphenol-d19 (2,4-DTBP-d19) is the deuterium labeled 2,4-Di-tert-butylphenol (HY-W014589). 2,4-Di-tert-butylphenol (2,4-DTBP) is an orally active RXRα activator and a human estrogen receptor ligand with anti-inflammatory and antioxidant activities, which can induce apoptosis in tumor cells. 2,4-Di-tert-butylphenol can activate the RXRα subtype in LXRα/RXRα, PPARγ/RXRα, and hormone receptor β/RXRα. 2,4-Di-tert-butylphenol also has antiviral and antifungal activities and has the potential to inhibit Aβ-induced neurotoxicity. 2,4-Di-tert-butylphenol can be used as an intermediate in the preparation of antioxidants and UV stabilizers, and is also used in the manufacture of drugs and fragrances.
    2,4-Di-tert-butylphenol-d19
  • HY-W014605R
    Diphenylcyclopropenone (Standard) 886-38-4 98%
    Diphenylcyclopropenone (Standard) is the analytical standard of Diphenylcyclopropenone. This product is intended for research and analytical applications. Diphenylcyclopropenone (Diphencyprone) is a topical immunomodulatory agent that can be used for alopecia areata research.
    Diphenylcyclopropenone (Standard)
  • HY-W014612R
    Eugenol acetate (Standard) 93-28-7 99.83%
    Eugenol acetate (Standard) is the analytical standard of Eugenol acetate. This product is intended for research and analytical applications. Eugenol acetate (Eugenyl acetate) is an antibacterial, anticancer, anti-inflammatory and antioxidant. Eugenol acetate inhibits NF-κB and enhances the expression of p53 and p21 (WAF1). Eugenol acetate can prevent chemically induced skin cancer, inhibit cancer cell proliferation and induce apoptosis.
    Eugenol acetate (Standard)
  • HY-W014701R
    1,4-Dihydroxy-2-naphthoic acid (Standard) 31519-22-9 98%
    1,4-Dihydroxy-2-naphthoic acid (Standard) is the analytical standard for 1,4-Dihydroxy-2-naphthoic acid (HY-W014701). 1,4-Dihydroxy-2-naphthoic acid is an orally active aryl hydrocarbon receptor (AhR) agonist and a bifidogenic growth stimulator. 1,4-Dihydroxy-2-naphthoic acid can improve the motor dysfunction in parkinson's disease (PD) model through AhR-dependent and -independent pathways. 1,4-Dihydroxy-2-naphthoic acid exerts anti-inflammatory effects by regulating the gut microbiota (such as promoting the proliferation of Bifidobacterium) and directly regulating the host immune system. 1,4-Dihydroxy-2-naphthoic acid induces apoptosis through G0/G1 cell cycle arrest in human keratinocyte to inhibit psoriasis.
    1,4-Dihydroxy-2-naphthoic acid (Standard)
  • HY-W015240R
    N-Acetyl-L-glutamic acid (Standard) 1188-37-0 98%
    N-Acetyl-L-glutamic acid (Standard) is the analytical standard of N-Acetyl-L-glutamic acid (HY-W015240). This product is intended for research and analytical applications. N-Acetyl-L-glutamic acid is a type of glutamic acid that can serve as a component of cell culture media. When combined with media containing inorganic salts, carbohydrates, vitamins, and amino acids, N-Acetyl-L-glutamic acid plays roles in promoting cell growth, enhancing antibody production, etc. N-Acetyl-L-glutamic acid is also an endogenous metabolite that can be found in the brain. Additionally, as an IgE blocker, N-Acetyl-L-glutamic acid can be used in the research of allergic diseases.
    N-Acetyl-L-glutamic acid (Standard)
  • HY-W015370R
    L-Lysine hydrate (Standard) 39665-12-8 98%
    Squalane (Standard) is the analytical standard of Squalane. This product is intended for research and analytical applications. Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities.
    L-Lysine hydrate (Standard)
  • HY-W015635R
    Diallyl disulfide (Standard) 2179-57-9
    Diallyl disulfide (Standard) is the analytical standard of Diallyl disulfide. This product is intended for research and analytical applications. Diallyl disulfide is an orally active decomposition product of allicin and has a pungent odor. Diallyl disulfide can act as a hydrogen sulfide donor. Diallyl disulfide has inhibitory activity against squalene monooxygenase with an IC50 of 400 μM. Diallyl disulfide can alleviate the cytotoxicity and apoptosis of intestinal and liver cells induced by Ethyl Carbamate (HY-B1207). Diallyl disulfide can prevent emphysema induced by cigarette smoke. Diallyl disulfide also has anti-colon cancer and anti-inflammatory neurogenic activities, and can reverse the depressive-like behavior of mice.
    Diallyl disulfide (Standard)
  • HY-W015820R
    Phthalide (Standard) 87-41-2 98%
    Phthalide (Standard) is an analytical standard of Phthalide. This product is intended for research and analytical applications. Phthalide is a chemical scaffold. Phthalide can be used to synthesize a variety of phthalate derivatives, including anti-inflammatory agents, antimicrobial agents, antioxidants and blood-tumor barrier regulators.
    Phthalide (Standard)
  • HY-W015879R
    2-Heptanol (Standard) 543-49-7 98%
    2-Heptanol (Standard) is the analytical standard of 2-Heptanol. This product is intended for research and analytical applications. 2-Heptanol is one of the chemical compounds identified in turmeric and turmeric rhizome essential oil. 2-Heptanol can speed up amino acid metabolism and slow down membrane transport, exhibiting antibacterial activity. The rhizome essential oil has good antibacterial and antioxidant properties[1][2].
    2-Heptanol (Standard)
  • HY-W016145S
    L-Glutamic acid-13C5 hydrate salt 202114-62-3 98%
    L-Glutamic acid-13C5 hydrate salt is the 13C labeled L-Glutamic acid hydrate salt. L-Glutamic acid monosodium hydrate is an excitatory amino acid neurotransmitter that acts as an agonist for all subtypes of glutamate receptors (metabolic rhodophylline, NMDA, and AMPA). L-Glutamic acid monosodium hydrate has an agonist effect on the release of DA from dopaminergic nerve endings. L-Glutamic acid monosodium hydrate can be used in the study of neurological diseases. L-Glutamic acid monosodium hydrate acts at ionotropic and?metabotropic glutamate receptors.
    L-Glutamic acid-13C5 hydrate salt
  • HY-W017443R
    L-Asparagine monohydrate (Standard) 5794-13-8 98%
    L-Asparagine monohydrate (Standard) is the analytical standard of L-Asparagine monohydrate (HY-W017443). This product is intended for research and analytical applications. L-Asparagine monohydrate is an essential amino acid for leukemic cells and a substrate for L-Asparaginase. L-Asparaginase is a potent anti-leukemic enzyme that promotes asparagine (Asn) and glutamine (Gln) depletion and inhibits protein biosynthesis in lymphoblasts. Removal of L-asparagine from plasma by L-Asparaginase results in inhibition of RNA and DNA synthesis and subsequent apoptosis. L-Asparaginase has cell-killing ability in vitro and in vivo, and selectively inhibits the growth of cancer cells with low asparagine synthetase (AASNS) expression. L-Asparagine monohydrate can be used as a biomarker and sensor for the study of childhood acute lymphoblastic leukemia.
    L-Asparagine monohydrate (Standard)
Cat. No. Product Name / Synonyms Application Reactivity